Abstract:
:A group of investigators met for two days in Santorini, Greece, to discuss progress in the field of identification and treatment of high risk/vulnerable atherosclerotic plaques and patients. Many differences in the manner in which terms are being utilized were noted. It was recognized that increased understanding of the pathophysiology of coronary thrombosis and onset of acute coronary syndromes has created the need for agreement on nomenclature. The participants spent considerable time discussing the topic and reached agreement on their own usage of the terms as described below. It is the hope that this usage might be of value to the larger community of scientists working in this field, and that widespread adoption of a common nomenclature would accelerate progress in the prevention of acute coronary events.
journal_name
Eur Heart Jjournal_title
European heart journalauthors
Schaar JA,Muller JE,Falk E,Virmani R,Fuster V,Serruys PW,Colombo A,Stefanadis C,Ward Casscells S,Moreno PR,Maseri A,van der Steen AFdoi
10.1016/j.ehj.2004.01.002subject
Has Abstractpub_date
2004-06-01 00:00:00pages
1077-82issue
12eissn
0195-668Xissn
1522-9645pii
S0195668X04000120journal_volume
25pub_type
共识发展会议,杂志文章,评审abstract:AIMS:Cardiovascular risk factors such as elevated serum lipid levels are important in the development of coronary atherosclerosis. Radiofrequency (RF) analysis of intravascular ultrasound [IVUS, Virtual histology (VH)] offers a unique tool to study the composition of coronary atherosclerotic plaque in vivo. We used dat...
journal_title:European heart journal
pub_type: 杂志文章,多中心研究
doi:10.1093/eurheartj/ehp428
更新日期:2010-01-01 00:00:00
abstract::We studied the effects of angiotensin (Ang) I and II in a variety of isolated human cardiac tissues contracting under physiological conditions (37 degrees C, 60 beats.min-1). Ang I and II consistently increased the peak developed force of human atrial muscles by 30-40%, an effect that was completely blocked by 10(-6) ...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/15.suppl_d.88
更新日期:1994-12-01 00:00:00
abstract:AIMS:To analyse the relationship between initial exercise parameters and peak oxygen consumption and prognosis in 96 patients with congestive heart failure. METHODS AND RESULTS:Comparison of responses during the initial 6 min of cardiopulmonary exercise testing (Naughton modified protocol) in patients stratified to th...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a015201
更新日期:1997-12-01 00:00:00
abstract:AIMS:Surgery in patients with infective endocarditis (IE) can be elective (upon completion of antibiotic treatment) or urgent (before antibiotic treatment has ended) when the clinical course is unfavourable. However, urgent surgery for left-sided endocarditis is associated with high mortality. The aims of this study we...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehl315
更新日期:2007-01-01 00:00:00
abstract::Among 369 patients with native valve infective endocarditis observed during a 14-year period, 17 were related to S: pneumoniae. Fourteen of them were observed in the last 7 years. At the time of admission 13 exhibited purulent meningitis, 6 of them being comatose. An apparent portal of entry was present in 13 patients...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/5.suppl_c.77
更新日期:1984-10-01 00:00:00
abstract::Aims Abciximab has previously been shown to enhance thrombolysis and improve myocardial perfusion when combined with reduced doses of alteplase. The purpose of the reteplase phase of TIMI 14 was to evaluate the effects of abciximab when used in combination with a reduced dose of reteplase for ST-elevation myocardial i...
journal_title:European heart journal
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1053/euhj.2000.2243
更新日期:2000-12-01 00:00:00
abstract:AIMS:The risk of gastrointestinal (GI) bleeding limits the use of antiplatelet and anticoagulant drugs. Risk factors for GI bleeding in post- myocardial infarction (MI) patients have not been well defined. We sought to identify risk factors for GI bleeding in patients following MI. METHODS AND RESULTS:The VALsartan In...
journal_title:European heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1093/eurheartj/ehp256
更新日期:2009-09-01 00:00:00
abstract:AIMS:We examined the adequacy of endogenous erythropoietin (EPO) levels for the degree of anaemia in patients with chronic heart failure (CHF) and its relation to prognosis. METHODS AND RESULTS:We studied 74 anaemic CHF patients from a cohort of 240 patients. The adequacy of endogenous EPO levels was assessed by deriv...
journal_title:European heart journal
pub_type: 杂志文章,多中心研究
doi:10.1093/eurheartj/ehn205
更新日期:2008-06-01 00:00:00
abstract::Intracranial mycotic aneurysms (IMA) occur in 1-3% of all infective endocarditis. Although spontaneous resolution was evidenced on serial angiograms in many asymptomatic cases, the prognosis, if they rupture, is reported to be worse and partly contingent on the therapeutic approach. Among 12 patients (six acute and si...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a059576
更新日期:1989-09-01 00:00:00
abstract:AIMS:Combined quantitative coronary angiography and intracoronary Doppler flow velocity measurements were performed to study the underlying haemodynamic mechanisms leading to myocardial ischaemia in patients with myocardial bridging in the absence of coronary artery disease. METHODS AND RESULTS:In 42 symptomatic patie...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a015263
更新日期:1997-03-01 00:00:00
abstract:AIM:Unstable coronary artery disease (CAD) is a multifactorial disease involving both thrombotic and inflammatory processes. We have assessed the time-course and the influence of thrombin inhibitors on changes in fibrinogen and C-reactive protein levels, and their relation to myocardial ischaemia in unstable CAD. METH...
journal_title:European heart journal
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0195-668x(02)00312-3
更新日期:2003-01-01 00:00:00
abstract::On the occasion of a routine medical check-up 256 out of 1100 individuals with an accumulation of coronary risk factors were screened for silent myocardial ischaemia by exercise testing and Holter monitoring. Of these individuals 5.5% had a pathological exercise test, 7.4% had ischaemia-like events on the Holter ECG, ...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/9.suppl_n.65
更新日期:1988-12-01 00:00:00
abstract:AIMS:To evaluate the predictive value and optimum dichotomy limits for different combinations of prognostic indicators for the prediction of arrhythmic events and cardiac mortality in post-infarction patients. BACKGROUND:Studies of new interventions based on risk stratification after myocardial infarction have often u...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a015439
更新日期:1997-08-01 00:00:00
abstract:AIMS:Anecdotal observations suggest that sub-clinical electrophysiological manifestations of arrhythmogenic right ventricular cardiomyopathy (ARVC) develop before detectable structural changes ensue on cardiac imaging. To test this hypothesis, we investigated a murine model with conditional cardiac genetic deletion of ...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehr472
更新日期:2012-08-01 00:00:00
abstract:AIMS:The management and outcomes of patients with functional moderate/severe mitral regurgitation and severe left ventricular (LV) systolic dysfunction are not well defined. We sought to determine the characteristics, management strategies, and outcomes of patients with moderate or severe mitral regurgitation (MR) and ...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehv343
更新日期:2015-10-21 00:00:00
abstract:AIMS:This study was designed to characterise both the systolic and diastolic mechanical properties of regions with different degrees of myocardial ischaemic injury after reperfused acute myocardial infarction (AMI). METHODS AND RESULTS:Fourteen dogs underwent 90-min coronary artery occlusion followed by reperfusion. I...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1016/j.ehj.2004.06.024
更新日期:2004-08-01 00:00:00
abstract:AIMS:The risk of stroke is greater among women with atrial fibrillation (AF) than men. Warfarin protects against stroke, but treatment-related bleeding occurs more often in women than in men. METHODS AND RESULTS:SPORTIF III (open label, n=3410) and V (double-blind, n=3922) included 2257 women with AF and one or more s...
journal_title:European heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1093/eurheartj/ehl103
更新日期:2006-08-01 00:00:00
abstract:AIMS:Growth differentiation factor 11 and/or its homologue growth differentiation factor 8 (GDF11/8) reverses age-related cardiac hypertrophy and vascular ageing in mice. We investigated whether GDF11/8 associates with cardiovascular outcomes, left ventricular hypertrophy (LVH), or age in humans. METHODS AND RESULTS:W...
journal_title:European heart journal
pub_type: 杂志文章,多中心研究
doi:10.1093/eurheartj/ehv385
更新日期:2015-12-21 00:00:00
abstract:AIMS:We designed this study in order to determine the effect of insulin on cardiac function in overweight and obese subjects during exercise. METHODS AND RESULTS:The cardiac function of 62 normal glucose tolerant subjects, aged 30-40 and divided into normal weight (group 1, n=22, BMI 20-24.9 kg/m(2)), overweight (grou...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehi271
更新日期:2005-06-01 00:00:00
abstract:AIMS:This investigation was set up to study the prevalence of left ventricular hypertrophy in a hypertensive population with reference to a normotensive control group. From the general population 3498 men and women aged 35, 45, 55 and 65 years old were invited to a health examination. Participants with blood pressure a...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a014672
更新日期:1996-01-01 00:00:00
abstract::Transthoracic echocardiography and continuous wave Doppler were prospectively performed in 132 out-patients with suspicion of pulmonary embolism, and who had no previous history of severe cardiac or pulmonary disease. Bedside echocardiography determined diagnosis other than pulmonary embolism in 55 patients. Further s...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a014946
更新日期:1996-05-01 00:00:00
abstract:AIMS:The very long-term outcome of patients who survive the first few years after receiving cardiac resynchronization therapy (CRT) has not been well described thus far. We aimed to provide long-term outcomes, especially with regard to the occurrence of sudden cardiac death (SCD), in CRT patients without (CRT-P) and wi...
journal_title:European heart journal
pub_type: 杂志文章,多中心研究
doi:10.1093/eurheartj/ehz238
更新日期:2019-07-01 00:00:00
abstract:AIMS :Individuals with low socioeconomic status (SES) face widespread prejudice in society. Whether SES disparities exist in treatment and survival following in-hospital cardiac arrest (IHCA) is unclear. The aim of the current retrospective registry study was to examine SES disparities in IHCA treatment and survival, a...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehaa954
更新日期:2020-12-21 00:00:00
abstract:BACKGROUND:Emerging evidence suggests that a mildly elevated body mass index (BMI), is related to improved survival and fewer cardiovascular events in patients with coronary artery disease (CAD). We hypothesize that these results are related to the poor diagnostic performance of BMI to detect adiposity, especially in t...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehm243
更新日期:2007-09-01 00:00:00
abstract::The European Myocardial Infarction Project (E.M.I.P.) participants have evaluated out-of-hospital coronary care services in different cities within the E.E.C. and concluded that these facilities would support a study within these European centres on pre-hospital intervention in myocardial infarction. Based on a pilot ...
journal_title:European heart journal
pub_type: 杂志文章
doi:
更新日期:1988-02-01 00:00:00
abstract:Aims:Canakinumab, a monoclonal antibody targeting interleukin (IL)-1β, reduces rates of recurrent cardiovascular events without lowering lipids. It is uncertain, however, to what extent these beneficial cardiovascular outcomes are mediated through interleukin-6 (IL-6) signalling, an issue with substantial pathophysiolo...
journal_title:European heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1093/eurheartj/ehy310
更新日期:2018-10-07 00:00:00
abstract:AIMS:Previous trials that investigated cell therapy as an adjunctive therapy after acute myocardial infarction (AMI) have shown conflicting results. We designed a randomized controlled trial to determine the effect of intracoronary infusion of mononuclear cells from bone marrow (BM) or peripheral blood in patients with...
journal_title:European heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1093/eurheartj/ehq449
更新日期:2011-07-01 00:00:00
abstract::The author reviews statistical methods commonly applied in economic evaluations that rely on individual patient-level data. The paper includes a review of foundational concepts, unique characteristics of health economic data, and methods developed to address them. The paper then highlights issues that should be consid...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehu174
更新日期:2014-07-01 00:00:00
abstract::Sequential alterations of left ventricular volumes and haemodynamics were studied in 29 patients between 4 days and 4 weeks after myocardial infarction. Left ventricular volume was determined by single photon emission computerized tomography (SPECT), infarct size by creatine kinase (CK) analysis, angiography and thall...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/11.suppl_b.139
更新日期:1990-04-01 00:00:00
abstract:Aims:Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by right ventricular myocardial replacement and life-threatening ventricular arrhythmias. Desmosomal gene mutations are sometimes identified, but clinical and genetic diagnosis remains challenging. Desmosomal skin disorders can be caused by de...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehy567
更新日期:2018-11-21 00:00:00