Terminology for high-risk and vulnerable coronary artery plaques. Report of a meeting on the vulnerable plaque, June 17 and 18, 2003, Santorini, Greece.

Abstract:

:A group of investigators met for two days in Santorini, Greece, to discuss progress in the field of identification and treatment of high risk/vulnerable atherosclerotic plaques and patients. Many differences in the manner in which terms are being utilized were noted. It was recognized that increased understanding of the pathophysiology of coronary thrombosis and onset of acute coronary syndromes has created the need for agreement on nomenclature. The participants spent considerable time discussing the topic and reached agreement on their own usage of the terms as described below. It is the hope that this usage might be of value to the larger community of scientists working in this field, and that widespread adoption of a common nomenclature would accelerate progress in the prevention of acute coronary events.

journal_name

Eur Heart J

journal_title

European heart journal

authors

Schaar JA,Muller JE,Falk E,Virmani R,Fuster V,Serruys PW,Colombo A,Stefanadis C,Ward Casscells S,Moreno PR,Maseri A,van der Steen AF

doi

10.1016/j.ehj.2004.01.002

subject

Has Abstract

pub_date

2004-06-01 00:00:00

pages

1077-82

issue

12

eissn

0195-668X

issn

1522-9645

pii

S0195668X04000120

journal_volume

25

pub_type

共识发展会议,杂志文章,评审
  • Do systemic risk factors impact invasive findings from virtual histology? Insights from the international virtual histology registry.

    abstract:AIMS:Cardiovascular risk factors such as elevated serum lipid levels are important in the development of coronary atherosclerosis. Radiofrequency (RF) analysis of intravascular ultrasound [IVUS, Virtual histology (VH)] offers a unique tool to study the composition of coronary atherosclerotic plaque in vivo. We used dat...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehp428

    authors: Philipp S,Böse D,Wijns W,Marso SP,Schwartz RS,König A,Lerman A,Garcia-Garcia HM,Serruys PW,Erbel R

    更新日期:2010-01-01 00:00:00

  • Functional significance of angiotensin receptors in human myocardium. Significant differences between atrial and ventricular myocardium.

    abstract::We studied the effects of angiotensin (Ang) I and II in a variety of isolated human cardiac tissues contracting under physiological conditions (37 degrees C, 60 beats.min-1). Ang I and II consistently increased the peak developed force of human atrial muscles by 30-40%, an effect that was completely blocked by 10(-6) ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/15.suppl_d.88

    authors: Holubarsch C,Schmidt-Schweda S,Knorr A,Duis J,Pieske B,Ruf T,Fasol R,Hasenfuss G,Just H

    更新日期:1994-12-01 00:00:00

  • Physiological parameters during the initial stages of cardiopulmonary exercise testing in patients with chronic heart failure. Their value in the assessment of clinical severity and prognosis.

    abstract:AIMS:To analyse the relationship between initial exercise parameters and peak oxygen consumption and prognosis in 96 patients with congestive heart failure. METHODS AND RESULTS:Comparison of responses during the initial 6 min of cardiopulmonary exercise testing (Naughton modified protocol) in patients stratified to th...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a015201

    authors: de Vries RJ,van Veldhuisen DJ,Dunselman PH,van der Veer N,Crijns HJ

    更新日期:1997-12-01 00:00:00

  • Clinical and prognostic profile of patients with infective endocarditis who need urgent surgery.

    abstract:AIMS:Surgery in patients with infective endocarditis (IE) can be elective (upon completion of antibiotic treatment) or urgent (before antibiotic treatment has ended) when the clinical course is unfavourable. However, urgent surgery for left-sided endocarditis is associated with high mortality. The aims of this study we...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehl315

    authors: Revilla A,López J,Vilacosta I,Villacorta E,Rollán MJ,Echevarría JR,Carrascal Y,Di Stefano S,Fulquet E,Rodríguez E,Fiz L,San Román JA

    更新日期:2007-01-01 00:00:00

  • Pneumococcal endocarditis.

    abstract::Among 369 patients with native valve infective endocarditis observed during a 14-year period, 17 were related to S: pneumoniae. Fourteen of them were observed in the last 7 years. At the time of admission 13 exhibited purulent meningitis, 6 of them being comatose. An apparent portal of entry was present in 13 patients...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/5.suppl_c.77

    authors: Wolff M,Regnier B,Witchitz S,Gibert C,Amoudry C,Vachon F

    更新日期:1984-10-01 00:00:00

  • Combination reperfusion therapy with abciximab and reduced dose reteplase: results from TIMI 14. The Thrombolysis in Myocardial Infarction (TIMI) 14 Investigators.

    abstract::Aims Abciximab has previously been shown to enhance thrombolysis and improve myocardial perfusion when combined with reduced doses of alteplase. The purpose of the reteplase phase of TIMI 14 was to evaluate the effects of abciximab when used in combination with a reduced dose of reteplase for ST-elevation myocardial i...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1053/euhj.2000.2243

    authors: Antman EM,Gibson CM,de Lemos JA,Giugliano RP,McCabe CH,Coussement P,Menown I,Nienaber CA,Rehders TC,Frey MJ,Van der Wieken R,Andresen D,Scherer J,Anderson K,Van de Werf F,Braunwald E

    更新日期:2000-12-01 00:00:00

  • Gastrointestinal bleeding in high risk survivors of myocardial infarction: the VALIANT Trial.

    abstract:AIMS:The risk of gastrointestinal (GI) bleeding limits the use of antiplatelet and anticoagulant drugs. Risk factors for GI bleeding in post- myocardial infarction (MI) patients have not been well defined. We sought to identify risk factors for GI bleeding in patients following MI. METHODS AND RESULTS:The VALsartan In...

    journal_title:European heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/eurheartj/ehp256

    authors: Moukarbel GV,Signorovitch JE,Pfeffer MA,McMurray JJ,White HD,Maggioni AP,Velazquez EJ,Califf RM,Scheiman JM,Solomon SD

    更新日期:2009-09-01 00:00:00

  • Adequacy of endogenous erythropoietin levels and mortality in anaemic heart failure patients.

    abstract:AIMS:We examined the adequacy of endogenous erythropoietin (EPO) levels for the degree of anaemia in patients with chronic heart failure (CHF) and its relation to prognosis. METHODS AND RESULTS:We studied 74 anaemic CHF patients from a cohort of 240 patients. The adequacy of endogenous EPO levels was assessed by deriv...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehn205

    authors: van der Meer P,Lok DJ,Januzzi JL,de la Porte PW,Lipsic E,van Wijngaarden J,Voors AA,van Gilst WH,van Veldhuisen DJ

    更新日期:2008-06-01 00:00:00

  • Prognosis of ruptured intracranial mycotic aneurysms: a review of 12 cases.

    abstract::Intracranial mycotic aneurysms (IMA) occur in 1-3% of all infective endocarditis. Although spontaneous resolution was evidenced on serial angiograms in many asymptomatic cases, the prognosis, if they rupture, is reported to be worse and partly contingent on the therapeutic approach. Among 12 patients (six acute and si...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a059576

    authors: Monsuez JJ,Vittecoq D,Rosenbaum A,Goujon C,Wolff M,Witchitz S,Modai J

    更新日期:1989-09-01 00:00:00

  • Functional characteristics of myocardial bridging. A combined angiographic and intracoronary Doppler flow study.

    abstract:AIMS:Combined quantitative coronary angiography and intracoronary Doppler flow velocity measurements were performed to study the underlying haemodynamic mechanisms leading to myocardial ischaemia in patients with myocardial bridging in the absence of coronary artery disease. METHODS AND RESULTS:In 42 symptomatic patie...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a015263

    authors: Schwarz ER,Klues HG,vom Dahl J,Klein I,Krebs W,Hanrath P

    更新日期:1997-03-01 00:00:00

  • Myocardial damage, inflammation and thrombin inhibition in unstable coronary artery disease.

    abstract:AIM:Unstable coronary artery disease (CAD) is a multifactorial disease involving both thrombotic and inflammatory processes. We have assessed the time-course and the influence of thrombin inhibitors on changes in fibrinogen and C-reactive protein levels, and their relation to myocardial ischaemia in unstable CAD. METH...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0195-668x(02)00312-3

    authors: Oldgren J,Wallentin L,Grip L,Linder R,Nørgaard BL,Siegbahn A

    更新日期:2003-01-01 00:00:00

  • Silent ischaemia in asymptomatic 'healthy' individuals with coronary risk factors.

    abstract::On the occasion of a routine medical check-up 256 out of 1100 individuals with an accumulation of coronary risk factors were screened for silent myocardial ischaemia by exercise testing and Holter monitoring. Of these individuals 5.5% had a pathological exercise test, 7.4% had ischaemia-like events on the Holter ECG, ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/9.suppl_n.65

    authors: Osterspey A,Treis-Müller I,Günther H,Eggeling T,Siglow C,Gedicke V,Höpp H,Diewitz M,Osterhues H,Hilger HH

    更新日期:1988-12-01 00:00:00

  • Selection of dichotomy limits for multifactorial prediction of arrhythmic events and mortality in survivors of acute myocardial infarction.

    abstract:AIMS:To evaluate the predictive value and optimum dichotomy limits for different combinations of prognostic indicators for the prediction of arrhythmic events and cardiac mortality in post-infarction patients. BACKGROUND:Studies of new interventions based on risk stratification after myocardial infarction have often u...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a015439

    authors: Redwood SR,Odemuyiwa O,Hnatkova K,Staunton A,Poloniecki I,Camm AJ,Malik M

    更新日期:1997-08-01 00:00:00

  • Electrophysiological abnormalities precede overt structural changes in arrhythmogenic right ventricular cardiomyopathy due to mutations in desmoplakin-A combined murine and human study.

    abstract:AIMS:Anecdotal observations suggest that sub-clinical electrophysiological manifestations of arrhythmogenic right ventricular cardiomyopathy (ARVC) develop before detectable structural changes ensue on cardiac imaging. To test this hypothesis, we investigated a murine model with conditional cardiac genetic deletion of ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehr472

    authors: Gomes J,Finlay M,Ahmed AK,Ciaccio EJ,Asimaki A,Saffitz JE,Quarta G,Nobles M,Syrris P,Chaubey S,McKenna WJ,Tinker A,Lambiase PD

    更新日期:2012-08-01 00:00:00

  • Management and outcomes in patients with moderate or severe functional mitral regurgitation and severe left ventricular dysfunction.

    abstract:AIMS:The management and outcomes of patients with functional moderate/severe mitral regurgitation and severe left ventricular (LV) systolic dysfunction are not well defined. We sought to determine the characteristics, management strategies, and outcomes of patients with moderate or severe mitral regurgitation (MR) and ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehv343

    authors: Samad Z,Shaw LK,Phelan M,Ersboll M,Risum N,Al-Khalidi HR,Glower DD,Milano CA,Alexander JH,O'Connor CM,Wang A,Velazquez EJ

    更新日期:2015-10-21 00:00:00

  • Persistent diastolic dysfunction despite complete systolic functional recovery after reperfused acute myocardial infarction demonstrated by tagged magnetic resonance imaging.

    abstract:AIMS:This study was designed to characterise both the systolic and diastolic mechanical properties of regions with different degrees of myocardial ischaemic injury after reperfused acute myocardial infarction (AMI). METHODS AND RESULTS:Fourteen dogs underwent 90-min coronary artery occlusion followed by reperfusion. I...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ehj.2004.06.024

    authors: Azevedo CF,Amado LC,Kraitchman DL,Gerber BL,Osman NF,Rochitte CE,Edvardsen T,Lima JA

    更新日期:2004-08-01 00:00:00

  • Anticoagulation in women with non-valvular atrial fibrillation in the stroke prevention using an oral thrombin inhibitor (SPORTIF) trials.

    abstract:AIMS:The risk of stroke is greater among women with atrial fibrillation (AF) than men. Warfarin protects against stroke, but treatment-related bleeding occurs more often in women than in men. METHODS AND RESULTS:SPORTIF III (open label, n=3410) and V (double-blind, n=3922) included 2257 women with AF and one or more s...

    journal_title:European heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/eurheartj/ehl103

    authors: Gomberg-Maitland M,Wenger NK,Feyzi J,Lengyel M,Volgman AS,Petersen P,Frison L,Halperin JL

    更新日期:2006-08-01 00:00:00

  • Association of growth differentiation factor 11/8, putative anti-ageing factor, with cardiovascular outcomes and overall mortality in humans: analysis of the Heart and Soul and HUNT3 cohorts.

    abstract:AIMS:Growth differentiation factor 11 and/or its homologue growth differentiation factor 8 (GDF11/8) reverses age-related cardiac hypertrophy and vascular ageing in mice. We investigated whether GDF11/8 associates with cardiovascular outcomes, left ventricular hypertrophy (LVH), or age in humans. METHODS AND RESULTS:W...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehv385

    authors: Olson KA,Beatty AL,Heidecker B,Regan MC,Brody EN,Foreman T,Kato S,Mehler RE,Singer BS,Hveem K,Dalen H,Sterling DG,Lawn RM,Schiller NB,Williams SA,Whooley MA,Ganz P

    更新日期:2015-12-21 00:00:00

  • Effects of insulin on left ventricular function during dynamic exercise in overweight and obese subjects.

    abstract:AIMS:We designed this study in order to determine the effect of insulin on cardiac function in overweight and obese subjects during exercise. METHODS AND RESULTS:The cardiac function of 62 normal glucose tolerant subjects, aged 30-40 and divided into normal weight (group 1, n=22, BMI 20-24.9 kg/m(2)), overweight (grou...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehi271

    authors: Sasso FC,Carbonara O,Nasti R,Marfella R,Esposito K,Rambaldi P,Mansi L,Salvatore T,Torella R,Cozzolino D

    更新日期:2005-06-01 00:00:00

  • Prevalence of left ventricular hypertrophy in a hypertensive population.

    abstract:AIMS:This investigation was set up to study the prevalence of left ventricular hypertrophy in a hypertensive population with reference to a normotensive control group. From the general population 3498 men and women aged 35, 45, 55 and 65 years old were invited to a health examination. Participants with blood pressure a...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a014672

    authors: Tingleff J,Munch M,Jakobsen TJ,Torp-Pedersen C,Olsen ME,Jensen KH,Jørgensen T,Kirchoff M

    更新日期:1996-01-01 00:00:00

  • Use of transthoracic Doppler echocardiography combined with clinical and electrocardiographic data to predict acute pulmonary embolism.

    abstract::Transthoracic echocardiography and continuous wave Doppler were prospectively performed in 132 out-patients with suspicion of pulmonary embolism, and who had no previous history of severe cardiac or pulmonary disease. Bedside echocardiography determined diagnosis other than pulmonary embolism in 55 patients. Further s...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a014946

    authors: Nazeyrollas P,Metz D,Jolly D,Maillier B,Jennesseaux C,Maes D,Chabert JP,Chapoutot L,Elaerts J

    更新日期:1996-05-01 00:00:00

  • Very long-term survival and late sudden cardiac death in cardiac resynchronization therapy patients.

    abstract:AIMS:The very long-term outcome of patients who survive the first few years after receiving cardiac resynchronization therapy (CRT) has not been well described thus far. We aimed to provide long-term outcomes, especially with regard to the occurrence of sudden cardiac death (SCD), in CRT patients without (CRT-P) and wi...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehz238

    authors: Barra S,Duehmke R,Providência R,Narayanan K,Reitan C,Roubicek T,Polasek R,Chow A,Defaye P,Fauchier L,Piot O,Deharo JC,Sadoul N,Klug D,Garcia R,Dockrill S,Virdee M,Pettit S,Agarwal S,Borgquist R,Marijon E,Boveda

    更新日期:2019-07-01 00:00:00

  • Discriminatory cardiac arrest care? Patients with low socioeconomic status receive delayed cardiopulmonary resuscitation and are less likely to survive an in-hospital cardiac arrest.

    abstract:AIMS :Individuals with low socioeconomic status (SES) face widespread prejudice in society. Whether SES disparities exist in treatment and survival following in-hospital cardiac arrest (IHCA) is unclear. The aim of the current retrospective registry study was to examine SES disparities in IHCA treatment and survival, a...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehaa954

    authors: Agerström J,Carlsson M,Bremer A,Herlitz J,Israelsson J,Årestedt K

    更新日期:2020-12-21 00:00:00

  • Diagnostic performance of body mass index to detect obesity in patients with coronary artery disease.

    abstract:BACKGROUND:Emerging evidence suggests that a mildly elevated body mass index (BMI), is related to improved survival and fewer cardiovascular events in patients with coronary artery disease (CAD). We hypothesize that these results are related to the poor diagnostic performance of BMI to detect adiposity, especially in t...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehm243

    authors: Romero-Corral A,Somers VK,Sierra-Johnson J,Jensen MD,Thomas RJ,Squires RW,Allison TG,Korinek J,Lopez-Jimenez F

    更新日期:2007-09-01 00:00:00

  • Potential time saving with pre-hospital intervention in acute myocardial infarction. Report of the European Myocardial Infarction Project (E.M.I.P) Sub-Committee.

    abstract::The European Myocardial Infarction Project (E.M.I.P.) participants have evaluated out-of-hospital coronary care services in different cities within the E.E.C. and concluded that these facilities would support a study within these European centres on pre-hospital intervention in myocardial infarction. Based on a pilot ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:

    authors:

    更新日期:1988-02-01 00:00:00

  • Modulation of the interleukin-6 signalling pathway and incidence rates of atherosclerotic events and all-cause mortality: analyses from the Canakinumab Anti-Inflammatory Thrombosis Outcomes Study (CANTOS).

    abstract:Aims:Canakinumab, a monoclonal antibody targeting interleukin (IL)-1β, reduces rates of recurrent cardiovascular events without lowering lipids. It is uncertain, however, to what extent these beneficial cardiovascular outcomes are mediated through interleukin-6 (IL-6) signalling, an issue with substantial pathophysiolo...

    journal_title:European heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/eurheartj/ehy310

    authors: Ridker PM,Libby P,MacFadyen JG,Thuren T,Ballantyne C,Fonseca F,Koenig W,Shimokawa H,Everett BM,Glynn RJ

    更新日期:2018-10-07 00:00:00

  • Intracoronary infusion of mononuclear cells from bone marrow or peripheral blood compared with standard therapy in patients after acute myocardial infarction treated by primary percutaneous coronary intervention: results of the randomized controlled HEBE

    abstract:AIMS:Previous trials that investigated cell therapy as an adjunctive therapy after acute myocardial infarction (AMI) have shown conflicting results. We designed a randomized controlled trial to determine the effect of intracoronary infusion of mononuclear cells from bone marrow (BM) or peripheral blood in patients with...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/ehq449

    authors: Hirsch A,Nijveldt R,van der Vleuten PA,Tijssen JG,van der Giessen WJ,Tio RA,Waltenberger J,ten Berg JM,Doevendans PA,Aengevaeren WR,Zwaginga JJ,Biemond BJ,van Rossum AC,Piek JJ,Zijlstra F,HEBE Investigators.

    更新日期:2011-07-01 00:00:00

  • Statistical considerations in economic evaluations: a guide for cardiologists.

    abstract::The author reviews statistical methods commonly applied in economic evaluations that rely on individual patient-level data. The paper includes a review of foundational concepts, unique characteristics of health economic data, and methods developed to address them. The paper then highlights issues that should be consid...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehu174

    authors: Reed SD

    更新日期:2014-07-01 00:00:00

  • Early remodelling of the left ventricle in patients with myocardial infarction.

    abstract::Sequential alterations of left ventricular volumes and haemodynamics were studied in 29 patients between 4 days and 4 weeks after myocardial infarction. Left ventricular volume was determined by single photon emission computerized tomography (SPECT), infarct size by creatine kinase (CK) analysis, angiography and thall...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/11.suppl_b.139

    authors: Gaudron P,Eilles C,Ertl G,Kochsiek K

    更新日期:1990-04-01 00:00:00

  • An autoantibody identifies arrhythmogenic right ventricular cardiomyopathy and participates in its pathogenesis.

    abstract:Aims:Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by right ventricular myocardial replacement and life-threatening ventricular arrhythmias. Desmosomal gene mutations are sometimes identified, but clinical and genetic diagnosis remains challenging. Desmosomal skin disorders can be caused by de...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehy567

    authors: Chatterjee D,Fatah M,Akdis D,Spears DA,Koopmann TT,Mittal K,Rafiq MA,Cattanach BM,Zhao Q,Healey JS,Ackerman MJ,Bos JM,Sun Y,Maynes JT,Brunckhorst C,Medeiros-Domingo A,Duru F,Saguner AM,Hamilton RM

    更新日期:2018-11-21 00:00:00