Natriuretic peptides in cardiovascular diseases: current use and perspectives.

abstract：:With the advent of therapeutic interventions to restore blood flow in patients with acute infarction, early identification of salvageable myocardium has gained clinical importance. It was the purpose of this study to define regional blood flow and glucose metabolism in patients with acute myocardial infarction as asse...

journal_title：European heart journal

authors： Schwaiger M,Brunken RC,Krivokapich J,Child JS,Tillisch JH,Phelps ME,Schelbert HR

更新日期：1987-09-01 00:00:00

abstract：:Patent foramen ovale (PFO) is implicated in the pathogenesis of a number of medical conditions but to date only one official position paper related to left circulation thromboembolism has been published. This interdisciplinary paper, prepared with the involvement of eight European scientific societies, reviews the ava...

journal_title：European heart journal

authors： Pristipino C,Germonpré P,Toni D,Sievert H,Meier B,D'Ascenzo F,Berti S,Onorato EM,Bedogni F,Mas JL,Scacciatella P,Hildick-Smith D,Gaita F,Kyrle PA,Thomson J,Derumeaux G,Sibbing D,Chessa M,Hornung M,Zamorano J,Dudek

更新日期：2021-01-28 00:00:00

abstract：AIMS:To test the hypothesis that increasing age in patients presenting with high-risk non-ST-segment elevation acute coronary syndromes (NSTE-ACS) does not adversely influence the benefit of an early invasive strategy on major adverse events at 6 months. METHODS AND RESULTS:We report clinical outcomes in young (<70), ...

journal_title：European heart journal

authors： Devlin G,Gore JM,Elliott J,Wijesinghe N,Eagle KA,Avezum A,Huang W,Brieger D,GRACE Investigators.

更新日期：2008-05-01 00:00:00

abstract：AIMS:This study investigated whether sedentary behaviour and different activity levels have an independent association with carotid intima-media thickness (IMT) and with the 3-year IMT progression in different carotid segments. METHODS AND RESULTS:The study population included 614 healthy men and women (mean age = 44 ...

journal_title：European heart journal

authors： Kozàkovà M,Palombo C,Morizzo C,Nolan JJ,Konrad T,Balkau B,RISC Investigators.

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:The syndrome with an electrocardiographic pattern of right bundle branch block, ST segment elevation in leads V(1)to V(3)and sudden death is genetically determined and caused by mutations in the cardiac sodium channel. The inheritance of the disease is autosomal dominant. Sudden death may, however, occur fro...

journal_title：European heart journal

authors： Brugada P,Brugada R,Brugada J

更新日期：2000-02-01 00:00:00

abstract：AIMS:The aim of this study was to compare on-thienopyridine platelet reactivity of elderly patients (≥75 years) vs. younger patients (<75 years). Elderly patients represent a growing and challenging segment of the coronary population for whom the effect of dual antiplatelet therapy on platelet inhibition has not been s...

journal_title：European heart journal

authors： Silvain J,Cayla G,Hulot JS,Finzi J,Kerneis M,O'Connor SA,Bellemain-Appaix A,Barthélémy O,Beygui F,Collet JP,Montalescot G

更新日期：2012-05-01 00:00:00

abstract：:Coronary heart disease (CHD) is the leading cause of death and disability in Europe. For patients presenting with an acute ST-segment elevation myocardial infarction (STEMI), timely myocardial reperfusion using either thrombolytic therapy or primary percutaneous coronary intervention (PPCI) is the most effective thera...

journal_title：European heart journal

authors： Fröhlich GM,Meier P,White SK,Yellon DM,Hausenloy DJ

更新日期：2013-06-01 00:00:00

abstract：:In seven patients with re-entry tachycardias and the implanted antitachycardia device Tachylog (Siemens Elema, Sweden) the variation in the termination window related to posture and exertion was investigated. The investigations were performed on an outpatient basis utilizing the interactive pacing mode of the implante...

journal_title：European heart journal

authors： Schmidinger H,Sowton E

更新日期：1988-09-01 00:00:00

abstract：:Chronic increases in haemodynamic load modify the expression of cardiac genes, leading to a new phenotype better adapted to the new functional demand. Several mechanisms such as the global activation of genes, the modulation of single genes and/or differential expression of multigene families may account for these mod...

journal_title：European heart journal

authors： Samuel JL,Dubus I,Contard F,Schwartz K,Rappaport L

更新日期：1990-11-01 00:00:00

abstract：AIMS:To assess the effect of experimentally induced atrial fibrillation on coronary flow in humans. METHODS AND RESULTS:In 16 patients (10 men, mean age 43+/-13 years) with normal coronary vessels, baseline and hyperaemic blood pressure and Doppler phasic coronary flow velocity were measured, using a 0.014 inch intrac...

journal_title：European heart journal

authors： Kochiadakis GE,Skalidis EI,Kalebubas MD,Igoumenidis NE,Chrysostomakis SI,Kanoupakis EM,Simantirakis EN,Vardas PE

更新日期：2002-05-01 00:00:00

abstract：:Bisoprolol is a new cardioselective beta-blocker with a long half-life. The efficacy of once daily bisoprolol (10 mg) and atenolol (100 mg) was assessed in 20 patients with stable angina using a placebo controlled double-blind randomized crossover protocol. Efficacy was assessed by computer assisted treadmill exercise...

journal_title：European heart journal

authors： Kohli RS,Khurmi NS,Kardash MM,Hughes LO,Lahiri A,Raftery EB

更新日期：1985-10-01 00:00:00

abstract：AIMS:we investigated the relationship between sublingual perfused capillary density (PCD) as a measure of tissue perfusion and outcome (i.e. occurrence of organ failure and mortality) in patients with cardiogenic shock from acute myocardial infarction. METHODS AND RESULTS:we performed a prospective study in 68 patient...

journal_title：European heart journal

authors： den Uil CA,Lagrand WK,van der Ent M,Jewbali LS,Cheng JM,Spronk PE,Simoons ML

更新日期：2010-12-01 00:00:00

abstract：AIMS:The aim of this study was to determine the outcome benefits in those originally assigned atorvastatin in the Anglo-Scandinavian Cardiac Outcomes Trial-8 years after closure of the lipid-lowering arm (LLA) of the trial (ASCOT-LLA) among the U.K. population. METHODS AND RESULTS:ASCOT-LLA was a factorially designed ...

journal_title：European heart journal

authors： Sever PS,Chang CL,Gupta AK,Whitehouse A,Poulter NR,ASCOT Investigators.

更新日期：2011-10-01 00:00:00

abstract：:Pilots and new applicants with asymptomatic 'safe' WPW syndrome should be allowed to fly but not as pilot in sole command. Professional pilots with tachyarrhythmia related to a pre-excitation syndrome should usually be disqualified . Personnel who have undergone successful surgical treatment by ablation of an accessor...

journal_title：European heart journal

authors： Ward D

更新日期：1984-03-01 00:00:00

abstract：:A recent report of the EuroHeart project has shown that women are still underrepresented in many cardiovascular clinical trials, while important gender differences are present within most areas of heart disease. As the burden of cardiovascular disease is increasing in middle-aged women relative to men, a more profound...

journal_title：European heart journal

authors： Maas AH,van der Schouw YT,Regitz-Zagrosek V,Swahn E,Appelman YE,Pasterkamp G,Ten Cate H,Nilsson PM,Huisman MV,Stam HC,Eizema K,Stramba-Badiale M

更新日期：2011-06-01 00:00:00

abstract：:In the interpretation of the effect of a drug or intervention in a single patient, it is desirable to know the spontaneous fluctuations of the variable under study. A few studies have determined pulmonary haemodynamic variability in acute and short-term intervals. It seems reasonable to adopt a confidence limit of 6 m...

journal_title：European heart journal

authors： Schrijen F,Jezková J

更新日期：1988-09-01 00:00:00

abstract：AIM:Previous studies have reported lifestyle and risk factor deterioration following completion of a cardiac rehabilitation program (CRP). We report the results of a one-year Extensive Lifestyle Management Intervention (ELMI) aimed at preventing these adverse changes. METHODS AND RESULTS:A total of 302 men and women w...

journal_title：European heart journal

authors： Lear SA,Ignaszewski A,Linden W,Brozic A,Kiess M,Spinelli JJ,Haydn Pritchard P,Frohlich JJ

更新日期：2003-11-01 00:00:00

abstract：:A possibility that can be advanced to explain the antihypertensive effect of beta-blocking drugs is that they act through the baroreflex control of the cardiovascular system. In 38 essential hypertensive patients we measured 1) The lengthening and shortening in R-R interval caused by stimulation or deactivation of art...

journal_title：European heart journal

authors： Parati G,Pomidossi G,Grassi G,Gavazzi C,Ramirez A,Gregorini L,Mancia G

更新日期：1983-07-01 00:00:00

abstract：Aims:Naturally secreted nanovesicles known as exosomes are required for the regenerative effects of cardiosphere-derived cells (CDCs), and exosomes mimic the benefits of CDCs in rodents. Nevertheless, exosomes have not been studied in a translationally realistic large-animal model. We sought to optimize delivery and as...

journal_title：European heart journal

authors： Gallet R,Dawkins J,Valle J,Simsolo E,de Couto G,Middleton R,Tseliou E,Luthringer D,Kreke M,Smith RR,Marbán L,Ghaleh B,Marbán E

更新日期：2017-01-14 00:00:00

abstract：Aims:Canakinumab, a monoclonal antibody targeting interleukin (IL)-1β, reduces rates of recurrent cardiovascular events without lowering lipids. It is uncertain, however, to what extent these beneficial cardiovascular outcomes are mediated through interleukin-6 (IL-6) signalling, an issue with substantial pathophysiolo...

journal_title：European heart journal

authors： Ridker PM,Libby P,MacFadyen JG,Thuren T,Ballantyne C,Fonseca F,Koenig W,Shimokawa H,Everett BM,Glynn RJ

更新日期：2018-10-07 00:00:00

abstract：:In 16 male patients with heart failure (NYHA II-III), the influence of a single dose of 25 mg captopril on the carotid sinus baroreceptor reflex was examined. Blood pressure fell significantly by 11 +/- 1.7 mm Hg (P less than 0.001), whereas heart rate remained unchanged (85 +/- 3 vs. 83 +/- 3 beats min-1). Carotid si...

journal_title：European heart journal

authors： Osterziel KJ,Röhrig N,Dietz R,Manthey J,Hecht J,Kübler W

更新日期：1988-10-01 00:00:00

abstract：:A 55-year-old woman presented with fever and malaise. Three blood cultures were positive for Streptococcus sanguis. A diagnosis of endocarditis was made and the patient was treated with intravenous penicillin and gentamicin. Endocardiography revealed a large left atrial tumour. At operation a myxoma covered by deposit...

journal_title：European heart journal

authors： ten Berg JM,Elbers HR,Defauw JJ,Plokker HW

更新日期：1992-11-01 00:00:00

abstract：:In the human heart the beta-adrenergic pathways are the primary means of increasing cardiac performance in response to acute or chronic stress. Control of beta pathway function is achieved by changes in the receptors themselves, and to a lesser degree by adjustments in the inhibitory G protein (Gi). In heart failure m...

journal_title：European heart journal

authors： Bristow MR,Port JD,Hershberger RE,Gilbert EM,Feldman AM

更新日期：1989-06-01 00:00:00

abstract：AIMS:Effects of the bradycardic agent ivabradine on regional blood flow, contractile function, and infarct size were studied in a pig model of myocardial ischaemia/reperfusion. Heart rate reduction by beta-blockade is associated with negative inotropism and unmasked alpha-adrenergic coronary vasoconstriction. Ivabradin...

journal_title：European heart journal

authors： Heusch G,Skyschally A,Gres P,van Caster P,Schilawa D,Schulz R

更新日期：2008-09-01 00:00:00

abstract：AIM:To describe the relative impact on survival of the delay from estimated time of collapse to call for an ambulance among patients who suffer from a bystander witnessed out of hospital cardiac arrest of a cardiac aetiology. METHODS:A majority of all ambulance organizations in Sweden (covering 85% of Sweden inhabitan...

journal_title：European heart journal

authors： Herlitz J,Engdahl J,Svensson L,Young M,Angquist KA,Holmberg S

更新日期：2003-10-01 00:00:00

abstract：:Left ventricular performance at rest and during supine symptom-limited exercise was determined by radionuclide ventriculography (RNV) in 65 subjects of the age of 65 years or older. Eleven subjects had no evidence of coronary artery disease (CAD) by history or submaximal stress ECG. In this control group left ventricu...

journal_title：European heart journal

authors： Pichler M,Mostbeck G,Fridrich L,Eghbalian F,Gassner A

更新日期：1984-11-01 00:00:00

abstract：AIMS:Real-time MRI creates images with superb tissue contrast that may enable radiation-free catheterization. Simple procedures are the first step towards novel interventional procedures. We aim to perform comprehensive transfemoral diagnostic right heart catheterization in an unselected cohort of patients entirely usi...

journal_title：European heart journal

authors： Ratnayaka K,Faranesh AZ,Hansen MS,Stine AM,Halabi M,Barbash IM,Schenke WH,Wright VJ,Grant LP,Kellman P,Kocaturk O,Lederman RJ

更新日期：2013-02-01 00:00:00

abstract：:Coronary revascularization procedures by means of percutaneous coronary interventions or coronary artery bypass graft surgeries are performed worldwide daily for the symptomatic treatment of patients with myocardial ischaemia. Nevertheless, angina remains a significant clinical problem. Management of angina recurring ...

journal_title：European heart journal

authors： Abbate A,Biondi-Zoccai GG,Agostoni P,Lipinski MJ,Vetrovec GW

更新日期：2007-05-01 00:00:00

abstract：:The electrocardiographic patterns, observed during 24-h Holter monitoring, of 10 patients (mean age 35 +/- 22 years) with first and second degree A-V block due to dual A-V nodal pathways are reported. Recordings were selected according to the presence of: sudden and persistent prolongation of the PR interval: sudden n...

journal_title：European heart journal

authors： Di Biase M,Tritto M,Sabato G,Pitzalis MV,Rizzon P

更新日期：1991-03-01 00:00:00

abstract：AIMS:A new generation of multidetector-row CT (MDCT) scanners allows complete coronary coverage using retrospective ECG gating and 1mm slices. The purpose of this study was to investigate the potential of high resolution MDCT angiography with retrospective gating for detection of coronary artery stenoses. METHODS AND ...

journal_title：European heart journal

authors： Kopp AF,Schroeder S,Kuettner A,Baumbach A,Georg C,Kuzo R,Heuschmid M,Ohnesorge B,Karsch KR,Claussen CD

更新日期：2002-11-01 00:00:00