High on-thienopyridine platelet reactivity in elderly coronary patients: the SENIOR-PLATELET study.

abstract：AIMS:Induced pluripotent stem cells (iPSCs) provide a unique opportunity for the generation of patient-specific cells for use in disease modelling, drug screening, and regenerative medicine. The aim of this study was to compare human-induced pluripotent stem cells (hiPSCs) derived from different somatic cell sources re...

journal_title：European heart journal

authors： Streckfuss-Bömeke K,Wolf F,Azizian A,Stauske M,Tiburcy M,Wagner S,Hübscher D,Dressel R,Chen S,Jende J,Wulf G,Lorenz V,Schön MP,Maier LS,Zimmermann WH,Hasenfuss G,Guan K

更新日期：2013-09-01 00:00:00

abstract：:Contradictory two-dimensional echocardiographic findings have been reported in relation to the role of prolapse of the mitral valve and lack of systolic leaflet coaptation in mitral regurgitation secondary to coronary heart disease. A prospective study of 22 patients with chronic coronary heart disease and mitral regu...

journal_title：European heart journal

authors： Ballester M,Tasca R,Marin L,Rees S,Rickards A,McDonald L

更新日期：1983-08-01 00:00:00

abstract：AIMS:We used the hospital discharge records of Piedmont region (northern Italy) to evaluate whether a national law banning smoking in public resulted in a short-term reduction in hospital admissions for acute myocardial infarction (AMI). METHODS AND RESULTS:Rates of admission for AMI before the ban (October-December 2...

journal_title：European heart journal

authors： Barone-Adesi F,Vizzini L,Merletti F,Richiardi L

更新日期：2006-10-01 00:00:00

abstract：AIMS:Subjects with lipoprotein(a) [Lp(a)] elevation have increased arterial wall inflammation and cardiovascular risk. In patients at increased cardiovascular risk, arterial wall inflammation is reduced following lipid-lowering therapy by statin treatment or lipoprotein apheresis. However, it is unknown whether lipid-l...

journal_title：European heart journal

authors： Stiekema LCA,Stroes ESG,Verweij SL,Kassahun H,Chen L,Wasserman SM,Sabatine MS,Mani V,Fayad ZA

更新日期：2019-09-01 00:00:00

abstract：:The aim of this study was to investigate the haemodynamic effects of amrinone in patients with pulmonary hypertension and impaired right ventricular function. Twelve patients with mitral stenosis (NYHA classification III and IV) took part in the study. The haemodynamic measurements were performed in the steady state u...

journal_title：European heart journal

authors： Hess W,Arnold B,Veit S

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:In the acute phase of myocardial infarction (acute MI) marked endothelial damage occurs within the first 24h following thrombolysis with streptokinase. We investigated whether this is associated with a change in levels of vascular endothelial growth factor (VEGF, possibly marking angiogenesis) in the first 2...

journal_title：European heart journal

authors： Chung NA,Lydakis C,Belgore F,Blann AD,Lip GY

更新日期：2002-10-01 00:00:00

abstract：AIMS:Morphological characteristics of non-significant coronary plaques (NSCPs) that develop rapid progression have not been fully elucidated. The aim of this study was to clarify the morphological characteristics of NSCPs in patients with coronary artery disease (CAD) using intravascular optical coherence tomography (O...

journal_title：European heart journal

authors： Uemura S,Ishigami K,Soeda T,Okayama S,Sung JH,Nakagawa H,Somekawa S,Takeda Y,Kawata H,Horii M,Saito Y

更新日期：2012-01-01 00:00:00

abstract：AIMS:LV reverse remodelling has been shown to be a favourable response after cardiac resynchronization therapy (CRT) in many clinical trials. This study investigated whether left ventricular (LV) reverse remodelling after CRT has any structural benefit, which include the improvement of LV mass or regional wall thicknes...

journal_title：European heart journal

authors： Zhang Q,Fung JW,Auricchio A,Chan JY,Kum LC,Wu LW,Yu CM

更新日期：2006-06-01 00:00:00

abstract：:Diastolic heart disease is common and appears to be the primary abnormality in a substantial proportion of all patients with CHF. The epidemiology and natural history of the condition appears different to that of systolic heart failure, resulting in significant morbidity although contributing little to overall mortali...

journal_title：European heart journal

authors： Wheeldon NM,Clarkson P,MacDonald TM

更新日期：1994-12-01 00:00:00

abstract：AIMS:The aim of this study was to evaluate the effect of valve surgery (VS) in infective endocarditis (IE) on 5-year mortality and to evaluate whether conflicting results reported by previous studies could be due to differences in their methodological approaches. METHODS AND RESULTS:Four hundred and forty-nine patient...

journal_title：European heart journal

authors： Bannay A,Hoen B,Duval X,Obadia JF,Selton-Suty C,Le Moing V,Tattevin P,Iung B,Delahaye F,Alla F,AEPEI Study Group.

更新日期：2011-08-01 00:00:00

abstract：:The electrocardiographic patterns, observed during 24-h Holter monitoring, of 10 patients (mean age 35 +/- 22 years) with first and second degree A-V block due to dual A-V nodal pathways are reported. Recordings were selected according to the presence of: sudden and persistent prolongation of the PR interval: sudden n...

journal_title：European heart journal

authors： Di Biase M,Tritto M,Sabato G,Pitzalis MV,Rizzon P

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:Maximal hyperaemia is paramount in the diagnosis of patients with coronary artery disease. However in these patients, enhanced alpha-adrenergic microvascular vasoconstriction may preclude adenosine to induce maximal hyperaemia. AIM:To assess the presence and the clinical relevance of residual microvascular ...

journal_title：European heart journal

authors： Barbato E,Bartunek J,Aarnoudse W,Vanderheyden M,Staelens F,Wijns W,Heyndrickx GR,Pijls NH,De Bruyne B

更新日期：2004-11-01 00:00:00

abstract：AIMS:Currently available non-invasive imaging methods frequently fail to detect alterations in left ventricular (LV) function despite histological evidence of injury. Tissue Doppler imaging (TDI) can detect subtle LV dysfunction. The aim of this study was to investigate whether TDI indices can predict LV systolic dysfu...

journal_title：European heart journal

authors： Neilan TG,Jassal DS,Perez-Sanz TM,Raher MJ,Pradhan AD,Buys ES,Ichinose F,Bayne DB,Halpern EF,Weyman AE,Derumeaux G,Bloch KD,Picard MH,Scherrer-Crosbie M

更新日期：2006-08-01 00:00:00

abstract：AIMS:To investigate the subacute effects of a sustained intravenous infusion of urocortin-I (Ucn-I) in experimental heart failure (HF). METHODS AND RESULTS:In eight sheep with pacing-induced HF, a 4-day infusion of Ucn-I (0.3 microg/kg/h) induced prompt (30 min) and sustained (4-day) increases in cardiac output (CO, D...

journal_title：European heart journal

authors： Rademaker MT,Charles CJ,Espiner EA,Frampton CM,Lainchbury JG,Richards AM

更新日期：2005-10-01 00:00:00

abstract：AIMS:Thrombin is an important factor in the pathogenesis of thrombotic diseases. To clarify whether smoking has an effect in platelet-dependent thrombogenesis, we studied the acute effects of smoking on platelet-dependent thrombin level in smokers. METHODS AND RESULTS:Subjects consisted of ten smokers and nine non-smo...

journal_title：European heart journal

authors： Hioki H,Aoki N,Kawano K,Homori M,Hasumura Y,Yasumura T,Maki A,Yoshino H,Yanagisawa A,Ishikawa K

更新日期：2001-01-01 00:00:00

abstract：:A case of severe iatrogenic fibrous left main coronary artery stenosis following aortic valve replacement (Hall-Kaster prosthesis) is documented clinically, angiographically and histologically. Reported histological data of this rare complication of valve replacement are reviewed. The onset of ischaemic symptoms in th...

journal_title：European heart journal

authors： Prachar H,Mühlbauer J,Pollak H,Enenkel W

更新日期：1988-10-01 00:00:00

abstract：:The effects of dexamethasone on cultured rat beating heart cells experimentally infected with coxsackievirus B2 were investigated at an early stage (1-3 days) post challenge. Changes in the release of the cardiac enzyme, aspartate amino-transferase (AST), beating %, cytopathic effect (CPE), virus titre, ultrastructure...

journal_title：European heart journal

authors： Yang YZ,Yuan WL,Guo Q,Gong ZX,Zhow TS,Shen JY,Chen HZ

更新日期：1991-08-01 00:00:00

abstract：:Hypertension induced in rats by suprarenal banding has a blood pressure elevating effect that is accompanied by the occurrence of cardiac hypertrophy and fibrosis. This phenomenon is already present at 2 weeks after banding and persists up to 1.5 years. The increase in cardiac weight is mostly due to the development o...

journal_title：European heart journal

authors： Nagasawa K,Zimmermann R,Münkel B,Linz W,Schölkens B,Schaper J

更新日期：1995-05-01 00:00:00

abstract：:Two patients with myocardial bridging of the left anterior descending coronary artery associated with myocardial infarction are described. One of them died from acute cerebral emboli related to cardiac thrombosis in a left ventricular aneurysm. The other died suddenly while sleeping. Both patients were found to have a...

journal_title：European heart journal

authors： Bestetti RB,Costa RS,Zucolotto S,Oliveira JS

更新日期：1989-06-01 00:00:00

abstract：AIMS:Aspirin combined with clopidogrel is the treatment of choice for acute coronary syndromes. Although the maintenance of aspirin until surgery does not affect postoperative bleeding after coronary artery bypass graft (CABG) surgery, the latter may be dramatically increased when clopidogrel is continued over a period...

journal_title：European heart journal

authors： Ouattara A,Bouzguenda H,Le Manach Y,Léger P,Mercadier A,Leprince P,Bonnet N,Montalescot G,Riou B,Coriat P

更新日期：2007-04-01 00:00:00

abstract：AIMS:Inflammatory markers are established risk factors for atrial fibrillation (AF), but the role of autoimmune diseases is unknown. The aim of the study was to examine the association between coeliac disease (CD) and AF in a large cohort of patients with biopsy-verified CD. METHODS AND RESULTS:We identified 28,637 pa...

journal_title：European heart journal

authors： Emilsson L,Smith JG,West J,Melander O,Ludvigsson JF

更新日期：2011-10-01 00:00:00

abstract：:This study was designed to evaluate the implantation of internal cardioverter/defibrillators under local anaesthesia by electrophysiologists and to compare this to our former experience of implants with general anaesthesia. Forty-seven internal cardioverter/defibrillators were implanted at our institution by electroph...

journal_title：European heart journal

authors： Schmitt C,Alt E,Plewan A,Schömig A

更新日期：1996-11-01 00:00:00

abstract：:A 22-year-old man who engaged in intense and regular physical exercise complained of atypical chest pain. The only remarkable abnormality found in the routine clinical work-up was a left posterior hemiblock. The echocardiogram and the magnetic resonance imaging (MRI) study showed a tumour in the posterior and superior...

journal_title：European heart journal

authors： Cola H,Hoffman R,Borrega NG,Lazzari JO

更新日期：1992-04-01 00:00:00

abstract：:We investigated whether left ventricular hypertrophy in elite cyclists is associated with functional changes or abnormal energy metabolism. Left ventricular hypertrophy is a powerful risk factor for sudden cardiac death with different prognostic significance among the various geometric forms. Cyclists may have a combi...

journal_title：European heart journal

authors： Pluim BM,Chin JC,De Roos A,Doornbos J,Siebelink HM,Van der Laarse A,Vliegen HW,Lamerichs RM,Bruschke AV,Van der Wall EE

更新日期：1996-08-01 00:00:00

abstract：AIMS:The totally subcutaneous implantable-defibrillator (S-ICD) is a new alternative to the conventional transvenous ICD system to minimize intravascular lead complications. There are limited data describing the long-term performance of the S-ICD. This paper presents the first large international patient population col...

journal_title：European heart journal

authors： Lambiase PD,Barr C,Theuns DA,Knops R,Neuzil P,Johansen JB,Hood M,Pedersen S,Kääb S,Murgatroyd F,Reeve HL,Carter N,Boersma L,EFFORTLESS Investigators.

更新日期：2014-07-01 00:00:00

abstract：:In the blood-vessel wall, the endothelium plays a key functional role by generating several substances that modulate vascular smooth muscle tone, as well as growth, and platelet function. This review focuses on the role of the endothelial L-arginine/nitric oxide signal transduction pathway in the maintenance of vascul...

journal_title：European heart journal

authors： Cosentino F,Lüscher TF

更新日期：1995-11-01 00:00:00

abstract：AIMS:Our aim was to follow changes in myocardial function and physiology in patients awaiting coronary artery bypass surgery (CABG) and relate changes to post-revascularisation functional response. METHODS AND RESULTS:In 21 patients with CAD and LV dysfunction, myocardial glucose utilisation (MGU) and blood flow (MBF)...

journal_title：European heart journal

authors： Pitt M,Dutka D,Pagano D,Camici P,Bonser R

更新日期：2004-03-01 00:00:00

abstract：:To assess the value of exercise stress testing and of mental stress as predictors of hypertension, we studied 130 normotensive males 14-18 years of age. Sixty-five had at least one hypertensive parent (SHT), while 65 had normotensive parents (SNT). Systolic (SBP) and diastolic (DBP) blood pressure, rate-pressure produ...

journal_title：European heart journal

authors： Radice M,Alli C,Avanzini F,Di Tullio M,Mariotti G,Taioli E,Zussino A,Folli G

更新日期：1985-06-01 00:00:00

abstract：AIMS:Benefits and complications of postoperative implantable cardioverter-defibrillator tests are controversial matters. This study sought to assess the necessity of defibrillation function tests after implantation. METHODS AND RESULTS:We retrospectively analysed 1007 implantable cardioverter-defibrillator tests in 58...

journal_title：European heart journal

authors： Brunn J,Böcker D,Weber M,Castrucci M,Gradaus R,Borggrefe M,Breithardt G,Block M

更新日期：2000-01-01 00:00:00

abstract：AIMS:Atrial fibrillation (AF) is associated with abnormal sarcoplasmic reticulum (SR) calcium release, which is promoted by adenosine A(2A) receptor (A(2A)R) activation. Here, we tested the hypothesis that abnormal calcium release in AF is linked to A(2A)R remodelling. METHODS AND RESULTS:Western blotting and quantita...

journal_title：European heart journal

authors： Llach A,Molina CE,Prat-Vidal C,Fernandes J,Casadó V,Ciruela F,Lluís C,Franco R,Cinca J,Hove-Madsen L

更新日期：2011-03-01 00:00:00