The impact of valve surgery on short- and long-term mortality in left-sided infective endocarditis: do differences in methodological approaches explain previous conflicting results?

Abstract:

AIMS:The aim of this study was to evaluate the effect of valve surgery (VS) in infective endocarditis (IE) on 5-year mortality and to evaluate whether conflicting results reported by previous studies could be due to differences in their methodological approaches. METHODS AND RESULTS:Four hundred and forty-nine patients with a definite left-sided IE were selected from a prospective, population-based study. Association between VS and 5-year mortality was examined with a Cox model. To determine the impact of different methodological approaches, we also analysed the relationship between VS and mortality in our database, according to each method used in the five previous studies. Valve surgery was performed in 240 patients (53%). It was associated with an increase in short-term mortality [within the first 14 post-operative days; adjusted hazard ratio (HR), 3.69; 95% confidence interval (CI), 2.17-6.25; P<0.0001] and a decrease in long-term mortality (adjusted HR, 0.55; 95% CI, 0.35-0.87; P=0.01). At least 188 days of follow-up were required for VS to provide an overall survival advantage. When applying each study's method to our database, we obtained results similar to those reported. CONCLUSION:Previous conflicting results appear to be related to differences in statistical methods. When using appropriate models, we found that VS was significantly associated with reduced long-term mortality.

journal_name

Eur Heart J

journal_title

European heart journal

authors

Bannay A,Hoen B,Duval X,Obadia JF,Selton-Suty C,Le Moing V,Tattevin P,Iung B,Delahaye F,Alla F,AEPEI Study Group.

doi

10.1093/eurheartj/ehp008

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

2003-15

issue

16

eissn

0195-668X

issn

1522-9645

pii

ehp008

journal_volume

32

pub_type

杂志文章
  • Quantitative analysis of the signal-averaged QRS in patients with arrhythmogenic right ventricular dysplasia.

    abstract::Temporal signal averaging of the surface QRS (V1 + V3 + V5) was performed in 16 patients with arrhythmogenic right ventricular dysplasia and in 16 normal subjects. The differences between ARVD patients and normals were large for the filtered QRS duration (FQRSd) (146.2 +/- 18.9 ms vs. 91.8 +/- 4.1 ms, P less than 0.00...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a062501

    authors: Blomström-Lundqvist C,Hirsch I,Olsson SB,Edvardsson N

    更新日期:1988-03-01 00:00:00

  • A double-blind, parallel-group comparison of flosequinan and enalapril in the treatment of chronic heart failure.

    abstract::The effects of flosequinan and enalapril on exercise capacity (bicycle exercise duration), quality-of-life symptomatology (visual analogue scales) and New York Heart Association (NYHA) grading, were compared in 61 patients with chronic heart failure (NYHA, grade III). Bicycle exercise duration improved similarly with ...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/oxfordjournals.eurheartj.a060320

    authors: Silke B,Tennet H,Fischer-Hansen J,Keller N,Heikkila J,Salminen K

    更新日期:1992-08-01 00:00:00

  • Impaired microcirculation predicts poor outcome of patients with acute myocardial infarction complicated by cardiogenic shock.

    abstract:AIMS:we investigated the relationship between sublingual perfused capillary density (PCD) as a measure of tissue perfusion and outcome (i.e. occurrence of organ failure and mortality) in patients with cardiogenic shock from acute myocardial infarction. METHODS AND RESULTS:we performed a prospective study in 68 patient...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehq324

    authors: den Uil CA,Lagrand WK,van der Ent M,Jewbali LS,Cheng JM,Spronk PE,Simoons ML

    更新日期:2010-12-01 00:00:00

  • High prevalence of right ventricular involvement in endurance athletes with ventricular arrhythmias. Role of an electrophysiologic study in risk stratification.

    abstract:BACKGROUND:Electrocardiographic abnormalities and premature ventricular contractions are common in athletes and are generally benign. However, the specific outcome of high-level endurance athletes with frequent and complex ventricular arrhythmias is unclear. Also, information on the predictive accuracy of different inv...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/s0195-668x(03)00282-3

    authors: Heidbüchel H,Hoogsteen J,Fagard R,Vanhees L,Ector H,Willems R,Van Lierde J

    更新日期:2003-08-01 00:00:00

  • Time-to-treatment significantly affects the extent of ST-segment resolution and myocardial blush in patients with acute myocardial infarction treated by primary angioplasty.

    abstract:AIMS:The prognostic role of time-to-treatment in primary angioplasty is still a matter of debate. The aim of our study was to evaluate the relationship between time-to-treatment and myocardial perfusion in patients with ST-segment-elevation myocardial infarction (STEMI) treated by primary angioplasty. METHODS AND RESU...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ehj.2004.03.021

    authors: De Luca G,van 't Hof AW,de Boer MJ,Ottervanger JP,Hoorntje JC,Gosselink AT,Dambrink JH,Zijlstra F,Suryapranata H

    更新日期:2004-06-01 00:00:00

  • Genes for blood pressure: an opportunity to understand hypertension.

    abstract::Hypertension (HTN) is quantitatively the major cardiovascular risk factor and responsible for ∼50% of cardiovascular morbidity and mortality. Blood pressure (BP) is also a classical complex genetic trait with heritability estimates of 30-50%. Although much is known about BP regulation, the intrinsic origin of essentia...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/ehs455

    authors: Ehret GB,Caulfield MJ

    更新日期:2013-04-01 00:00:00

  • Dietary counselling has no effect on cardiovascular risk factors among Chinese Grade 1 hypertensive patients: a randomized controlled trial.

    abstract:AIMS:To evaluate the effectiveness of Dietary Approaches to Stop Hypertension (DASH) by one-off dietary counselling on reducing cardiovascular risk factors among Chinese Grade 1 hypertensive patients in primary care. METHODS AND RESULTS:A parallel-group, randomized controlled trial (ChiCTR-TRC-13003014) was conducted ...

    journal_title:European heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/eurheartj/ehv329

    authors: Wong MC,Wang HH,Kwan MW,Fong BC,Chan WM,Zhang DX,Li ST,Yan BP,Coats AJ,Griffiths SM

    更新日期:2015-10-07 00:00:00

  • Quantifying the heart failure epidemic: prevalence, incidence rate, lifetime risk and prognosis of heart failure The Rotterdam Study.

    abstract:AIMS:To determine the prevalence, incidence rate, lifetime risk and prognosis of heart failure. METHODS AND RESULTS:The Rotterdam Study is a prospective population-based cohort study in 7983 participants aged > or =55. Heart failure was defined according to criteria of the European Society of Cardiology. Prevalence wa...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ehj.2004.06.038

    authors: Bleumink GS,Knetsch AM,Sturkenboom MC,Straus SM,Hofman A,Deckers JW,Witteman JC,Stricker BH

    更新日期:2004-09-01 00:00:00

  • What is the role of invasive intervention after coronary thrombolysis?

    abstract::Intervention to improve coronary flow after coronary patency has been restored by coronary thrombolysis is attractive in concept, but has been proved disappointing in practice. A number of randomized clinical trials which compared outcome after thrombolysis with and without early or delayed intervention has shown no b...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:

    authors: de Bono DP

    更新日期:1991-12-01 00:00:00

  • The ability of QRST isointegral maps to detect myocardial infarction in the presence of simulated left bundle branch block.

    abstract::The clinical value of QRST isointegral maps (I-maps) for the detection of myocardial infarction (MI) in the presence of left bundle branch block (LBBB) was investigated. We recorded I-maps during sinus rhythm and right ventricular (RV) pacing, which simulated LBBB, in 62 patients with MI (42 patients had at least one ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/14.8.1094

    authors: Suzuki A,Hirai M,Hayashi H,Tomita Y,Ichihara Y,Adachi M,Oguchi S,Takatsu F

    更新日期:1993-08-01 00:00:00

  • Assessment of endothelial function by non-invasive peripheral arterial tonometry predicts late cardiovascular adverse events.

    abstract:AIMS:There is growing need for the identification of novel non-invasive methodologies for the identification of individuals at risk for adverse cardiovascular (CV) events. We examined whether endothelial dysfunction, as detected by non-invasive peripheral arterial tonometry (EndoPAT), can predict late CV events. METHO...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehq010

    authors: Rubinshtein R,Kuvin JT,Soffler M,Lennon RJ,Lavi S,Nelson RE,Pumper GM,Lerman LO,Lerman A

    更新日期:2010-05-01 00:00:00

  • Clinical and economic impact of exercise electrocardiography and exercise echocardiography in clinical practice.

    abstract:BACKGROUND:Patients with known or suspected coronary disease are often investigated to facilitate risk assessment. We sought to examine the cost-effectiveness of strategies based on exercise echocardiography and exercise electrocardiography. METHODS AND RESULTS:We studied 7656 patients undergoing exercise testing; of ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1016/s0195-668x(03)00113-1

    authors: Marwick TH,Shaw L,Case C,Vasey C,Thomas JD

    更新日期:2003-06-01 00:00:00

  • Haemodynamic response to exercise in patients with chest pain and normal coronary angiograms.

    abstract::A series of 42 patients with chest pain but normal coronary angiograms and normal haemodynamics at rest were prospectively classified as typical angina (group 1, N = 9) or atypical angina (group 2, N = 16) or non-anginal chest pain (group 3, N = 17). All patients underwent radionuclide ventriculography and measurement...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a062119

    authors: Wieshammer S,Delagardelle C,Sigel HA,Henze E,Kress P,Bitter F,Adam WE,Stauch M

    更新日期:1986-08-01 00:00:00

  • Outbursts of anger as a trigger of acute cardiovascular events: a systematic review and meta-analysis.

    abstract:AIM:Short-term psychological stress is associated with an immediate physiological response and may be associated with a transiently higher risk of cardiovascular events. The aim of this study was to determine whether brief episodes of anger trigger the onset of acute myocardial infarction (MI), acute coronary syndromes...

    journal_title:European heart journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.1093/eurheartj/ehu033

    authors: Mostofsky E,Penner EA,Mittleman MA

    更新日期:2014-06-01 00:00:00

  • Beneficial effects of chronic low-frequency stimulation of thigh muscles in patients with advanced chronic heart failure.

    abstract:AIMS:Patients with chronic heart failure (CHF) exhibit detrimental changes in skeletal muscle that contribute to their impaired physical performance. This study investigates the possibility of counteracting these changes by chronic low-frequency electrical stimulation (CLFS) of left and right thigh muscles. METHODS AN...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.ehj.2003.09.027

    authors: Nuhr MJ,Pette D,Berger R,Quittan M,Crevenna R,Huelsman M,Wiesinger GF,Moser P,Fialka-Moser V,Pacher R

    更新日期:2004-01-01 00:00:00

  • Transdermal nitroglycerin in angina pectoris.

    abstract::The transdermal nitroglycerin patches have been very successful nitrate formulations since their introduction in 1982. Nevertheless, considerable controversy regarding efficacy and tolerance has arisen. Nitroglycerin has multiple mechanisms of action in angina pectoris. Transdermal nitroglycerin in ointment formulatio...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/10.suppl_a.11

    authors: Abrams J

    更新日期:1989-05-01 00:00:00

  • High-density lipoprotein, but not low-density lipoprotein cholesterol levels influence short-term prognosis after acute coronary syndrome: results from the MIRACL trial.

    abstract:AIMS:Patients with acute coronary syndrome (ACS) in the Myocardial Ischaemia Reduction with Aggressive Cholesterol Lowering (MIRACL) study had diminished cardiovascular events after 16 weeks of treatment of atorvastatin 80 mg daily. We determined whether plasma lipoproteins at baseline and then at 6 weeks after randomi...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/eurheartj/ehi186

    authors: Olsson AG,Schwartz GG,Szarek M,Sasiela WJ,Ezekowitz MD,Ganz P,Oliver MF,Waters D,Zeiher A

    更新日期:2005-05-01 00:00:00

  • Trans-fatty acids and mortality in patients referred for coronary angiography: the Ludwigshafen Risk and Cardiovascular Health Study.

    abstract:AIMS:Trans-fatty acids (TFAs) are generated by the food industry and also occur naturally in trace amounts in dairy products. For the latter, beneficial health effects have been claimed, while there are numerous reports about TFA of industrial origin being hazardous to human health. Therefore, we aimed to investigate t...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehv446

    authors: Kleber ME,Delgado GE,Lorkowski S,März W,von Schacky C

    更新日期:2016-04-01 00:00:00

  • Long-lasting sport practice and lone atrial fibrillation.

    abstract:AIMS:To analyse whether the proportion of patients with lone atrial fibrillation engaged in chronic sport practice was higher than that observed in the general population. METHODS AND RESULTS:The records of 1160 patients, seen at the arrhythmia outpatient clinic, were reviewed. A total of 70 patients (6%) suffered lon...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1053/euhj.2001.2802

    authors: Mont L,Sambola A,Brugada J,Vacca M,Marrugat J,Elosua R,Paré C,Azqueta M,Sanz G

    更新日期:2002-03-01 00:00:00

  • Randomized trial of an inhibitor of secretory phospholipase A2 on atherogenic lipoprotein subclasses in statin-treated patients with coronary heart disease.

    abstract:AIMS:To investigate the effects of secretory phospholipase A2 (sPLA(2)) inhibition on plasma lipoproteins. Secretory phospholipase A2 isoenzymes promote atherosclerosis by mechanisms that include lipoprotein modification, retention, and oxidation. METHODS AND RESULTS:Phospholipase Levels And Serological Markers of Ath...

    journal_title:European heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/eurheartj/ehq374

    authors: Rosenson RS,Elliott M,Stasiv Y,Hislop C,PLASMA II Investigators.

    更新日期:2011-04-01 00:00:00

  • Influence of high cardiovascular risk in asymptomatic people on the duration and cost of sick leave: results of the ICARIA study.

    abstract:AIMS:We investigated the potential influence of a moderate-to-high cardiovascular (CV) risk (CVR) (defined as a Systematic COronary Risk Evaluation model, or SCORE ≥ 4%), in the absence of an established CV disease, on the duration and cost of CV and non-CV sick leave (SL) resulting from common and occupational acciden...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/eht156

    authors: Calvo-Bonacho E,Ruilope LM,Sánchez-Chaparro MA,Cerezo C,Catalina-Romero C,Martínez-Muñoz P,Banegas JR,Waeber B,Gonzalez-Quintela A,Zanchetti A

    更新日期:2014-02-01 00:00:00

  • A double-blind comparison of the long-term efficacy of a potassium channel opener and a calcium antagonist in stable angina pectoris.

    abstract::The efficacies and safety of nicorandil, 20 mg b.d., and diltiazem, 60 mg t.d., in the treatment of stable angina pectoris were compared in a double-blind randomized parallel group study involving 123 patients. The duration of the study was 3 months. Exercise tolerance tests were performed by the patients when on plac...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/14.suppl_b.30

    authors: Guermonprez JL,Blin P,Peterlongo F

    更新日期:1993-07-01 00:00:00

  • Plans of the British Cardiovascular Society to seek patients' views on research may aid research grant applications.

    abstract::Priorities for unanswered questions concerning major areas of cardiovascular disease are being sought by the British Cardiovascular Society, using the methods of the James Lind Alliance, which involves clinicians and patients in an equal partnership, reports Barry Shurlock PhD. ...

    journal_title:European heart journal

    pub_type: 新闻

    doi:

    authors:

    更新日期:2015-06-01 00:00:00

  • Impact of final coronary flow velocity reserve on late outcome following stent implantation.

    abstract::Aims To assess whether coronary flow velocity reserve following stent implantation is predictive of the subsequent need of target lesion revascularization. Methods and Results The outcome was examined of 417 patients enrolled in a multicentre prospective randomized study (DESTINI), who received a successful single ves...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1053/euhj.2001.2734

    authors: Nishida T,Di Mario C,Kern MJ,Anderson TJ,Moussa I,Bonan R,Muramatsu T,Jain AC,Suarez de Lezo J,Cho SY,Meredith IT,Moses JW,Colombo A

    更新日期:2002-02-01 00:00:00

  • Do systemic risk factors impact invasive findings from virtual histology? Insights from the international virtual histology registry.

    abstract:AIMS:Cardiovascular risk factors such as elevated serum lipid levels are important in the development of coronary atherosclerosis. Radiofrequency (RF) analysis of intravascular ultrasound [IVUS, Virtual histology (VH)] offers a unique tool to study the composition of coronary atherosclerotic plaque in vivo. We used dat...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehp428

    authors: Philipp S,Böse D,Wijns W,Marso SP,Schwartz RS,König A,Lerman A,Garcia-Garcia HM,Serruys PW,Erbel R

    更新日期:2010-01-01 00:00:00

  • Electrocardiographic left ventricular hypertrophy in GUSTO IV ACS: an important risk marker of mortality in women.

    abstract:AIM:To examine the association of left ventricular hypertrophy (LVH) on admission electrocardiography with adverse outcomes in acute coronary syndrome (ACS) patients. METHODS AND RESULTS:A total of 7443 non-ST-elevation ACS patients in Global Utilization of STrategies to Open occluded arteries (GUSTO) IV ACS trial had...

    journal_title:European heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/eurheartj/ehm223

    authors: Westerhout CM,Lauer MS,James S,Fu Y,Wallentin L,Armstrong PW,GUSTO IV ACS Investigators.

    更新日期:2007-09-01 00:00:00

  • Angiographic dose-finding study with r-hirudin (HBW 023) for the improvement of thrombolytic therapy with streptokinase (HIT-SK). Interim results.

    abstract::To evaluate the efficacy and safety of hirudin, a direct thrombin inhibitor, in patients with acute myocardial infarction, a dose-finding, angiography study was carried out. After a pilot phase in 10 patients treated with a bolus of 0.1 mg.kg-1 and a continuous infusion of 0.06 mg.kg-1.h-1 (dose group I), two doses of...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/16.suppl_d.33

    authors: Molhoek GP,Laarman GJ,Lok DJ,Luz CM,Kingma JH,Van den Bos AA,Zijnen P,Bosma AH,Hertzberger DP,Takens LH

    更新日期:1995-07-01 00:00:00

  • Lipoproteins in chronic kidney disease: from bench to bedside.

    abstract::Chronic kidney disease (CKD) is associated with high cardiovascular risk. CKD patients exhibit a specific lipoprotein pattern termed 'uraemic dyslipidaemia', which is characterized by rather normal low-density lipoprotein cholesterol, low high-density lipoprotein cholesterol, and high triglyceride plasma levels. All t...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehaa1050

    authors: Speer T,Ridker PM,von Eckardstein A,Schunk SJ,Fliser D

    更新日期:2021-01-04 00:00:00

  • The codex of science: honesty, precision, and truth--and its violations.

    abstract::Science has made enormous achievements for our understanding of the world and for everyday life: we now know that we live on a spherical planet of the solar system, we understand the origin of the species, we can take a train, survive myocardial infarction, and fly to the moon. This has been made possible thanks to a ...

    journal_title:European heart journal

    pub_type: 历史文章,杂志文章

    doi:10.1093/eurheartj/eht063

    authors: Lüscher TF

    更新日期:2013-04-01 00:00:00

  • Intravascular ultrasound evaluation after sirolimus eluting stent implantation for de novo and in-stent restenosis lesions.

    abstract:AIMS:The aim of this study is to compare the efficacy of sirolimus-eluting stents (SES) on neointimal growth and vessel remodelling for in-stent restenosis versus de novo coronary artery lesions using serial intravascular ultrasound (IVUS). METHODS AND RESULTS:The study population consisted of 86 patients with in-sten...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ehj.2003.10.012

    authors: Degertekin M,Lemos PA,Lee CH,Tanabe K,Sousa JE,Abizaid A,Regar E,Sianos G,van der Giessen WJ,de Feyter PJ,Wuelfert E,Popma JJ,Serruys PW

    更新日期:2004-01-01 00:00:00