Angiographic dose-finding study with r-hirudin (HBW 023) for the improvement of thrombolytic therapy with streptokinase (HIT-SK). Interim results.

abstract：:We now have conclusive data that ACE inhibitors reduce mortality, morbidity, and symptoms in patients with low ejection fraction and/or heart failure. Therefore, ACE inhibitors should be routinely used in all such patients, as long as there are no clear contraindications. Routine use of ACE inhibitors will lead to pro...

journal_title：European heart journal

authors： McKelvie R,McConachie D,Yusuf S

更新日期：1994-05-01 00:00:00

abstract：:The importance of fibrinogen has been identified in two prospective observational studies. Reactive elevations in fibrinogen levels that occur within hours of a major stroke invalidate most cross-sectional case-control studies evaluating fibrinogen as a risk factor. However, as no elevation is seen following fresh epi...

journal_title：European heart journal

authors： Qizilbash N

更新日期：1995-03-01 00:00:00

abstract：:Supraventricular tachycardia is due to altered automaticity, triggered activity or most commonly, reentry. Atrial flutter is most frequently due to reentry with counterclockwise activation in the right atrium with the left atrium acting as a bystander. The small wavefronts demonstrated during atrial fibrillation are l...

journal_title：European heart journal

authors： Shakespeare CF,Anderson M,Camm AJ

更新日期：1993-09-01 00:00:00

abstract：AIMS:To evaluate the effects of cardiac resynchronization therapy (CRT) on long-term survival of patients without baseline left ventricular (LV) mechanical dyssynchrony. METHODS AND RESULTS:A total of 290 heart failure patients (age 67 ± 10 years, 77% males) without significant baseline LV dyssynchrony (<60 ms as asse...

journal_title：European heart journal

authors： Auger D,Bleeker GB,Bertini M,Ewe SH,van Bommel RJ,Witkowski TG,Ng AC,van Erven L,Schalij MJ,Bax JJ,Delgado V

更新日期：2012-04-01 00:00:00

abstract：AIMS:Monocytes are critical mediators of healing following acute myocardial infarction (AMI), making them an interesting target to improve myocardial repair. The purpose of this study was a gain of insight into the source and recruitment of monocytes following AMI in humans. METHODS AND RESULTS:Post-mortem tissue spec...

journal_title：European heart journal

authors： van der Laan AM,Ter Horst EN,Delewi R,Begieneman MP,Krijnen PA,Hirsch A,Lavaei M,Nahrendorf M,Horrevoets AJ,Niessen HW,Piek JJ

更新日期：2014-02-01 00:00:00

abstract：:Organic nitrates exert their effect by direct inhibition of vascular tone, resulting in decreased myocardial oxygen demand and improved oxygen supply. Less well known is the effect of nitrates on blood rheology. To evaluate the haemodiluting effect of intravenous nitroglycerin we studied 70 consecutive patients admitt...

journal_title：European heart journal

authors： Arend SM,Bax JJ,Hermans J,van der Wall EE,Sedney MI

更新日期：1994-01-01 00:00:00

abstract：AIMS:Long-term randomized comparisons of percutaneous coronary intervention (PCI) to coronary artery bypass grafting (CABG) in left main coronary (LM) disease and/or three-vessel disease (3VD) patients have been limited. This analysis compares 3-year outcomes in LM and/or 3VD patients treated with CABG or PCI with TAXU...

journal_title：European heart journal

authors： Kappetein AP,Feldman TE,Mack MJ,Morice MC,Holmes DR,Ståhle E,Dawkins KD,Mohr FW,Serruys PW,Colombo A

更新日期：2011-09-01 00:00:00

abstract：AIMS:Growth-differentiation factor-15 (GDF-15) has emerged as a biomarker of increased mortality and recurrent myocardial infarction (MI) in patients diagnosed with non-ST-elevation acute coronary syndrome. We explored the usefulness of GDF-15 for early risk stratification in 479 unselected patients with acute chest pa...

journal_title：European heart journal

authors： Eggers KM,Kempf T,Allhoff T,Lindahl B,Wallentin L,Wollert KC

更新日期：2008-10-01 00:00:00

abstract：:The present study was carried out to evaluate systolic and diastolic parameters in overweight and moderately obese, but otherwise healthy subjects, and in a lean control group, to determine whether degree and duration of obesity can influence left ventricular function. A total of 27 subjects, 17 overweight or with mod...

journal_title：European heart journal

authors： Scaglione R,Dichiara MA,Indovina A,Lipari R,Ganguzza A,Parrinello G,Capuana G,Merlino G,Licata G

更新日期：1992-06-01 00:00:00

abstract：:In 13 patients with chronic stable angina, left ventricular pressures were measured by catheter-tip micromanometer, and left cineventriculography was performed at matched atrial paced rates before and 20 min after administration of intravenous gallopamil (3 mg). Mean plasma concentration of gallopamil at the second ha...

journal_title：European heart journal

authors： Di Mario C,Iavernaro A,Cucchini F

更新日期：1991-09-01 00:00:00

abstract：AIMS:Cardiac biomarkers are routinely elevated after uncomplicated cardiac surgery to levels considered diagnostic of myocardial infarction in ambulatory populations. We investigated the diagnostic power of electrocardiogram (ECG) and cardiac biomarker criteria to predict clinically relevant myocardial injury using ben...

journal_title：European heart journal

authors： Muehlschlegel JD,Perry TE,Liu KY,Nascimben L,Fox AA,Collard CD,Avery EG,Aranki SF,D'Ambra MN,Shernan SK,Body SC,CABG Genomics Investigators.

更新日期：2009-07-01 00:00:00

abstract：:On the occasion of a routine medical check-up 256 out of 1100 individuals with an accumulation of coronary risk factors were screened for silent myocardial ischaemia by exercise testing and Holter monitoring. Of these individuals 5.5% had a pathological exercise test, 7.4% had ischaemia-like events on the Holter ECG, ...

journal_title：European heart journal

authors： Osterspey A,Treis-Müller I,Günther H,Eggeling T,Siglow C,Gedicke V,Höpp H,Diewitz M,Osterhues H,Hilger HH

更新日期：1988-12-01 00:00:00

abstract：AIMS:Cardiomyopathy produces significant mortality in patients with Friedreich ataxia (FA), a genetic disorder that produces intra-mitochondrial iron accumulation. We sought to test the hypothesis that abnormal myocardial perfusion reserve and fibrosis represent early manifestations of cardiomyopathy. METHODS AND RESU...

journal_title：European heart journal

authors： Raman SV,Phatak K,Hoyle JC,Pennell ML,McCarthy B,Tran T,Prior TW,Olesik JW,Lutton A,Rankin C,Kissel JT,Al-Dahhak R

更新日期：2011-03-01 00:00:00

abstract：:In 2008, The ESC Working Group on Myocardial and Pericardial Diseases proposed an updated classification of cardiomyopathies based on morphological and functional phenotypes and subcategories of familial/genetic and non-familial/non-genetic disease. In this position statement, we propose a framework for the clinical a...

journal_title：European heart journal

authors： Rapezzi C,Arbustini E,Caforio AL,Charron P,Gimeno-Blanes J,Heliö T,Linhart A,Mogensen J,Pinto Y,Ristic A,Seggewiss H,Sinagra G,Tavazzi L,Elliott PM

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Oral dipyridamole induces accumulation of endogenous adenosine, which in a hypoxic milieu exerts experimentally an angiogenic effect on coronary collateral circulation. A meta-analysis of 13 randomized placebo-controlled trials published between 1960 and 1992 showed evidence of benefit for dipyridamole in th...

journal_title：European heart journal

authors： Picano E,PISA (Persantin In Stable Angina) study group.

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Recent identification of mutations in the beta-myosin heavy chain gene (MYH7), a major responsible gene for HCM, has provided the opportunity to characterize genotype-phenotype correlation in HCM families. In this study we analysed the phenotypic expression of two beta-myosin heavy chain (beta MHC) mutations...

journal_title：European heart journal

authors： Marian AJ,Mares A Jr,Kelly DP,Yu QT,Abchee AB,Hill R,Roberts R

更新日期：1995-03-01 00:00:00

abstract：AIMS:Collagen degradation in atherosclerotic plaques with thin fibrous caps renders them more prone to rupture. Fibroblast activation protein (FAP) plays a role in arthritis and tumour formation through its collagenase activity. However, the significance of FAP in thin-cap human fibroatheromata remains unknown. METHOD...

journal_title：European heart journal

authors： Brokopp CE,Schoenauer R,Richards P,Bauer S,Lohmann C,Emmert MY,Weber B,Winnik S,Aikawa E,Graves K,Genoni M,Vogt P,Lüscher TF,Renner C,Hoerstrup SP,Matter CM

更新日期：2011-11-01 00:00:00

abstract：:Activation of the sympathetic nervous system may contribute to the renal vasoconstriction and sodium retention seen in congestive heart failure. Previous studies in congestive heart failure patients employing large doses of prazosin that lowered systemic blood pressure have been generally disappointing. The renal haem...

journal_title：European heart journal

authors： Lang CC,Choy AM,Rahman AR,Struthers AD

更新日期：1993-09-01 00:00:00

abstract：:To assess the prevalence of asymmetric septal hypertrophy (ASH) in hypertensive patients, 613 echocardiographic examinations performed over a period of one year were reviewed. Asymmetric septal hypertrophy (defined by an echocardiographic interventricular septum to left ventricular free wall thickness ratio of greater...

journal_title：European heart journal

authors： Wicker P,Roudaut R,Haissaguere M,Villega-Arino P,Clementy J,Dallocchio M

更新日期：1983-11-01 00:00:00

abstract：AIMS:Psoriasis is a chronic inflammatory disease and inflammation contributes to the pathogenesis of atrial fibrillation (AF) and ischaemic stroke. We therefore investigated the risk of these endpoints in patients with psoriasis. METHODS AND RESULTS:Cohort study of the entire Danish population followed from 1997 to 20...

journal_title：European heart journal

authors： Ahlehoff O,Gislason GH,Jørgensen CH,Lindhardsen J,Charlot M,Olesen JB,Abildstrøm SZ,Skov L,Torp-Pedersen C,Hansen PR

更新日期：2012-08-01 00:00:00

abstract：Aims:Bioresorbable scaffolds (BRS) provide short-term coronary artery scaffolding and drug delivery. Although prior trials showed a higher rate of device failure compared with conventional drug-eluting stents (DES), only a single trial investigated patients undergoing percutaneous coronary intervention (PCI) for acute ...

journal_title：European heart journal

authors： Byrne RA,Alfonso F,Schneider S,Maeng M,Wiebe J,Kretov E,Bradaric C,Rai H,Cuesta J,Rivero F,Hoppmann P,Schlichtenmaier J,Christiansen EH,Cassese S,Joner M,Schunkert H,Laugwitz KL,Kastrati A

更新日期：2019-01-07 00:00:00

abstract：AIMS:Although dilated cardiomyopathy is the most frequent form of cardiomyopathy, its aetiology is still poorly understood. In about 20-30% of cases the disease is familial with a large predominance of autosomal dominant transmission. Ten different chromosomal loci have been described for autosomal dominant forms of di...

journal_title：European heart journal

authors： Tesson F,Sylvius N,Pilotto A,Dubosq-Bidot L,Peuchmaurd M,Bouchier C,Benaiche A,Mangin L,Charron P,Gavazzi A,Tavazzi L,Arbustini E,Komajda M

更新日期：2000-11-01 00:00:00

abstract：:The aim of this study was to determine whether sudden cardiac death from pulmonary embolism exhibits any chronobiological rhythm. Five hundred and seven consecutive subjects dying suddenly outside of hospital and brought into our Emergency Department from January 1983 to December 1989 were studied. The time and date o...

journal_title：European heart journal

authors： Gallerani M,Manfredini R,Ricci L,Grandi E,Cappato R,Calò G,Pareschi PL,Fersini C

更新日期：1992-05-01 00:00:00

abstract：:A necessary part of the strategy of modification of hypercholesterolaemia to prevent coronary heart disease (CHD) is the detection and treatment, by diet or by drugs, of high risk individuals. There are several drawbacks to this approach: (1) the cost of screening to find individuals at risk and of monitoring by physi...

journal_title：European heart journal

authors： Marmot MG

更新日期：1987-08-01 00:00:00

abstract：:Anthony N. DeMaria discusses the journal's history, its focus,and innovative ideas for Internet reading. ...

journal_title：European heart journal

authors： Taylor J

更新日期：2012-02-01 00:00:00

abstract：:Left ventricular pressure overload results in the development of left ventricular hypertrophy (LVH) which is considered an adaptive mechanism of the heart to normalize systolic wall-stress. Impairment of both contractility and relaxation occurs, implying that the hypertrophied myocardium is very sensitive to ischaemia...

journal_title：European heart journal

authors： Viallard JF,Bonoron-Adele S,Dos Santos P,Coste P,Besse P

更新日期：1993-11-01 00:00:00

abstract：AIM:A genetic variant (rs20417) of the PTGS2 gene, encoding for COX-2, has been associated with decreased COX-2 activity and a decreased risk of cardiovascular disease (CVD). However, this genetic association and the role of COX-2 in CVD remain controversial. METHODS AND RESULTS:The association of rs20417 with CVD was...

journal_title：European heart journal

authors： Ross S,Eikelboom J,Anand SS,Eriksson N,Gerstein HC,Mehta S,Connolly SJ,Rose L,Ridker PM,Wallentin L,Chasman DI,Yusuf S,Paré G

更新日期：2014-09-01 00:00:00

abstract：:The immediate and short-term results of coronary angioplasty were analysed in 16 patients who presented with chest pain at rest associated with transient marked ST-segment elevation (greater than or equal to 0.5 mV). The number of in hospital ischaemic attacks was on average 2.8 (range 1-8). All patients had at least ...

journal_title：European heart journal

authors： de Feyter PJ,Serruys PW,van den Brand M,Soward A

更新日期：1987-06-01 00:00:00

abstract：AIMS :In the last decade, transcatheter aortic valve (TAV) replacement determined a paradigm shift in the treatment of patients with severe symptomatic aortic stenosis. Data on long-term TAV performance are still limited. We sought to evaluate the clinical and haemodynamic outcomes of the CoreValve self-expandable valv...

journal_title：European heart journal

authors： Testa L,Latib A,Brambilla N,De Marco F,Fiorina C,Adamo M,Giannini C,Angelillis M,Barbanti M,Sgroi C,Poli A,Ferrara E,Bruschi G,Russo CF,Matteo M,De Felice F,Musto C,Curello S,Colombo A,Tamburino C,Petronio AS,Be

更新日期：2020-05-21 00:00:00

abstract：AIMS:A small reference diameter may be the consequence of high plaque burden and diffuse disease. The reference vessel diameter in small coronary arteries may vary according to the method of measurement used. We endeavoured to confirm the difference between data from examinations conducted using angiography with that r...

journal_title：European heart journal

authors： Briguori C,Tobis J,Nishida T,Vaghetti M,Albiero R,Di Mario C,Colombo A

更新日期：2002-02-01 00:00:00