Psoriasis and risk of atrial fibrillation and ischaemic stroke: a Danish Nationwide Cohort Study.

Abstract:

AIMS:Psoriasis is a chronic inflammatory disease and inflammation contributes to the pathogenesis of atrial fibrillation (AF) and ischaemic stroke. We therefore investigated the risk of these endpoints in patients with psoriasis. METHODS AND RESULTS:Cohort study of the entire Danish population followed from 1997 to 2006 by individual-level-linkage of nationwide prospectively recorded registers. Multivariable Poisson's regression and sensitivity analyses were used to assess the psoriasis-related risk of AF and ischaemic stroke. A total of 36 765 patients with mild psoriasis and 2793 with severe psoriasis were compared with 4 478 926 individuals, i.e., the reference population. In patients with mild psoriasis, the adjusted rate ratios (RRs) for AF were 1.50 (1.21-1.86) and 1.16 (1.08-1.24) in patients aged <50 and ≥50 years, respectively. Patients with severe psoriasis had a higher risk of AF with RRs 2.98 (1.80-4.92) in patients aged <50 years and 1.29 (1.01-1.65) in patients aged ≥50 years. Patients with psoriasis also demonstrated a disease severity-dependent increased risk of ischaemic stroke, i.e. RRs 1.97 (1.66-2.34) and 2.80 (1.81-4.34) in patients aged <50 years with mild and severe psoriasis, and RRs 1.13 (1.04-1.21) and 1.34 (1.04-1.71) in patients aged ≥50 years with mild and severe psoriasis, respectively. A range of sensitivity analyses yielded comparable results. CONCLUSION:Psoriasis is associated with increased risk of AF and ischaemic stroke. These novel results add to a growing body of evidence, suggesting that patients with psoriasis could be considered at increased cardiovascular risk.

journal_name

Eur Heart J

journal_title

European heart journal

authors

Ahlehoff O,Gislason GH,Jørgensen CH,Lindhardsen J,Charlot M,Olesen JB,Abildstrøm SZ,Skov L,Torp-Pedersen C,Hansen PR

doi

10.1093/eurheartj/ehr285

subject

Has Abstract

pub_date

2012-08-01 00:00:00

pages

2054-64

issue

16

eissn

0195-668X

issn

1522-9645

pii

ehr285

journal_volume

33

pub_type

杂志文章
  • Prognostic value of right ventricular mass, volume, and function in idiopathic pulmonary arterial hypertension.

    abstract:AIMS:This study investigated the relationship between right ventricular (RV) structure and function and survival in idiopathic pulmonary arterial hypertension (IPAH). METHODS AND RESULTS:In 64 patients, cardiac magnetic resonance, right heart catheterization, and the six-minute walk test (6MWT) were performed at basel...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehl477

    authors: van Wolferen SA,Marcus JT,Boonstra A,Marques KM,Bronzwaer JG,Spreeuwenberg MD,Postmus PE,Vonk-Noordegraaf A

    更新日期:2007-05-01 00:00:00

  • International economic analysis of primary prevention of cardiovascular disease with pravastatin in WOSCOPS. West of Scotland Coronary Prevention Study.

    abstract:AIMS:The results of the West of Scotland Coronary Prevention Study (WOSCOPS) demonstrated the clinical benefit of using pravastatin for the primary prevention of cardiovascular disease in hypercholesterolaemic men. To inform decision makers, who must also consider costs, this study assesses the economic efficiency of s...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1053/euhj.1999.1193

    authors: Caro J,Klittich W,McGuire A,Ford I,Pettitt D,Norrie J,Shepherd J

    更新日期:1999-02-01 00:00:00

  • Strain rate imaging for functional quantification of the left atrium: atrial deformation predicts the maintenance of sinus rhythm after catheter ablation of atrial fibrillation.

    abstract:AIMS:The aim of the study was to investigate the atrial myocardial deformation properties using ultrasound strain rate (SR) imaging in patients after catheter ablation of atrial fibrillation (AF) and to compare its prognostic value in maintaining sinus rhythm. METHODS AND RESULTS:A total of 118 patients with AF (74 pa...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehn168

    authors: Schneider C,Malisius R,Krause K,Lampe F,Bahlmann E,Boczor S,Antz M,Ernst S,Kuck KH

    更新日期:2008-06-01 00:00:00

  • Transcoronary gradients of vascular miRNAs and coronary atherosclerotic plaque characteristics.

    abstract:AIMS:Circulating microRNAs (miRs) may reflect pathophysiologically relevant processes in the atherosclerotically diseased coronary arterial wall. Given the unmet medical need to identify patients with an unstable plaque phenotype, we determined the relation of circulating atherosclerosis-regulatory miRs with plaque phe...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehw047

    authors: Leistner DM,Boeckel JN,Reis SM,Thome CE,De Rosa R,Keller T,Palapies L,Fichtlscherer S,Dimmeler S,Zeiher AM

    更新日期:2016-06-07 00:00:00

  • Heart rate variability and ischaemia in patients with coronary heart disease and stable angina pectoris; influence of drug therapy and prognostic value. TIBBS Investigators Group. Total Ischemic Burden Bisoprolol Study.

    abstract:AIMS:Determination of the influence of therapy with bisoprolol and nifedipine on the heart rate variability of patients from the Total Ischemic Burden Bisoprolol Study and examination of the prognostic value. METHODS AND RESULTS:Four hundred and twenty-two patients with stable angina were included. The heart rate vari...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1053/euhj.1998.1272

    authors: Weber F,Schneider H,von Arnim T,Urbaszek W

    更新日期:1999-01-01 00:00:00

  • Prophylaxis of respiratory tract infection in patients on artificial respiration.

    abstract::In a pilot study, a prophylactic regimen including ciprofloxacin and amphotericin B was applied in 102 consecutive patients on artificial respiration for greater than or equal to 5 days to prevent respiratory tract infection with aerobic Gram-negative bacilli. Ciprofloxacin was given twice a day, as 500 mg through a g...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/10.suppl_h.22

    authors: Haverkorn MJ

    更新日期:1989-12-01 00:00:00

  • Electrocardiographic left ventricular hypertrophy in GUSTO IV ACS: an important risk marker of mortality in women.

    abstract:AIM:To examine the association of left ventricular hypertrophy (LVH) on admission electrocardiography with adverse outcomes in acute coronary syndrome (ACS) patients. METHODS AND RESULTS:A total of 7443 non-ST-elevation ACS patients in Global Utilization of STrategies to Open occluded arteries (GUSTO) IV ACS trial had...

    journal_title:European heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/eurheartj/ehm223

    authors: Westerhout CM,Lauer MS,James S,Fu Y,Wallentin L,Armstrong PW,GUSTO IV ACS Investigators.

    更新日期:2007-09-01 00:00:00

  • Increased risk of sudden and non-sudden cardiovascular death in patients with atrial fibrillation/flutter following acute myocardial infarction.

    abstract:AIMS:Atrial fibrillation (AF) is a common complication in patients with acute myocardial infarction and is associated with an increase in the risk of death. The excess mortality associated with AF complicating acute myocardial infarction has not been studied in detail. Observations indicate that AF facilitates inductio...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/ehi629

    authors: Pedersen OD,Abildstrøm SZ,Ottesen MM,Rask-Madsen C,Bagger H,Køber L,Torp-Pedersen C,TRACE Study Investigators.

    更新日期:2006-02-01 00:00:00

  • The left atrial appendage: from embryology to prevention of thromboembolism.

    abstract::The left atrial appendage (LAA) is the main source of thromboembolism in patients with non-valvular atrial fibrillation (AF). As such, the LAA can be the target of specific occluding device therapies. Optimal management of patients with AF includes a comprehensive knowledge of the many aspects related to LAA structure...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehw159

    authors: Patti G,Pengo V,Marcucci R,Cirillo P,Renda G,Santilli F,Calabrò P,De Caterina AR,Cavallari I,Ricottini E,Parato VM,Zoppellaro G,Di Gioia G,Sedati P,Cicchitti V,Davì G,Golia E,Pariggiano I,Simeone P,Abbate R,Prisco

    更新日期:2017-03-21 00:00:00

  • Inflammatory biomarkers, physical activity, waist circumference, and risk of future coronary heart disease in healthy men and women.

    abstract:AIMS:The aim of this study was to determine the contribution of physical activity and abdominal obesity to the variation in inflammatory biomarkers and incident coronary heart disease (CHD) in a European population. METHODS AND RESULTS:In a prospective case-control study nested in the European Prospective Investigatio...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehp010

    authors: Rana JS,Arsenault BJ,Després JP,Côté M,Talmud PJ,Ninio E,Wouter Jukema J,Wareham NJ,Kastelein JJ,Khaw KT,Boekholdt SM

    更新日期:2011-02-01 00:00:00

  • Management of atrial fibrillation: discrepancy between guideline recommendations and actual practice exposes patients to risk for complications.

    abstract:AIMS:To assess compliance to guidelines in the management of patients with atrial fibrillation. METHODS AND RESULTS:A total of 728 questionnaires were mailed to physicians with the intention of studying 'theoretical' compliance to practice guidelines. A retrospective evaluation of 200 records from consecutive patients...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1053/euhj.2000.2300

    authors: Frykman V,Beerman B,Rydén L,Rosenqvist M,Medical Products Agency.,Swedish Society of Cardiology.

    更新日期:2001-10-01 00:00:00

  • Endothelin-1 and acute myocardial infarction: a no-reflow mediator after successful percutaneous myocardial revascularization.

    abstract:AIMS:No-reflow after a primary percutaneous coronary intervention (PCI) is associated with a high incidence of left ventricular (LV) failure and a poor prognosis. Endothelin-1 (ET-1) is a potent endothelium-derived vasoconstrictor peptide and an important modulator of neutrophil function. Elevated systemic ET-1 levels ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehl119

    authors: Niccoli G,Lanza GA,Shaw S,Romagnoli E,Gioia D,Burzotta F,Trani C,Mazzari MA,Mongiardo R,De Vita M,Rebuzzi AG,Lüscher TF,Crea F

    更新日期:2006-08-01 00:00:00

  • Effect of revascularizing viable myocardium on left ventricular diastolic function in patients with ischaemic cardiomyopathy.

    abstract:AIMS:In patients with ischaemic left ventricular (LV) dysfunction and viable myocardium, revascularization improves systolic function. Diastolic dysfunction is also present in such patients; however, whether revascularization improves diastolic function also is largely unknown. METHODS:Twenty-six patients with chronic...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehp125

    authors: Carluccio E,Biagioli P,Alunni G,Murrone A,Leonelli V,Pantano P,Vincenti G,Giombolini C,Ragni T,Reboldi G,Gentile F,Ambrosio G

    更新日期:2009-06-01 00:00:00

  • New electrocardiographic leads and the procainamide test for the detection of the Brugada sign in sudden unexplained death syndrome survivors and their relatives.

    abstract:AIMS:Sudden unexplained death syndrome occurs in previously healthy South-east Asian young adults without any structural cause of death. The common electrocardiographic (ECG) change in sudden unexplained death syndrome survivors is right bundle branch block and ST elevations in leads V(1) to V(3), which are similar to ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1053/euhj.2001.2691

    authors: Sangwatanaroj S,Prechawat S,Sunsaneewitayakul B,Sitthisook S,Tosukhowong P,Tungsanga K

    更新日期:2001-12-01 00:00:00

  • Improved monitoring of myocardial ischaemia during major vascular surgery using transoesophageal echocardiography.

    abstract::As regional wall motion abnormality (RWA) is the first sign of ischaemia, transoesophageal echocardiography was evaluated as a monitoring device in 51 patients undergoing abdominal aortic surgery. Wall motion of the entire left ventricular wall (nine segments) was semiquantitatively evaluated 15 min before and after a...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a060309

    authors: Koolen JJ,Visser CA,Reichert SL,Jaarsma WJ,Kromhout JG,van Wezel HB,Dunning AJ

    更新日期:1992-08-01 00:00:00

  • Evolution of coronary atherosclerosis in patients with mild coronary artery disease studied by serial quantitative coronary angiography at 2 and 4 years follow-up. The Multicenter Anti-Atheroma Study (MAAS) Investigators.

    abstract:AIMS:Angiographic studies on the natural course of both focal and diffuse coronary atherosclerosis have not been performed before, but can both be assessed by quantitative coronary angiography. The objective of this study was to describe the natural course of focal and diffuse coronary atherosclerosis over time. METHO...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/oxfordjournals.eurheartj.a015401

    authors: Vos J,de Feyter PJ,Kingma JH,Emanuelsson H,Legrand V,Winkelmann B,Dumont JM,Simoons LM

    更新日期:1997-07-01 00:00:00

  • Indices of effectiveness of medical and surgical treatment in 40 cases of prosthetic valve endocarditis.

    abstract::Forty patients with prosthetic valve endocarditis (PVE) presenting during a 12-year period at a single hospital were studied. Twenty-six were male and 14 female and ages ranged from 19 to 67 years. During the first six post-operative months, most episodes were caused by staphylococci (38%) and Gram negative bacilli (2...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/5.suppl_c.133

    authors: Gayet JL,Etienne J,Malquarti V,Gruer LD,Didier B,Chuzel M,Champsaur G,Chassignolle J,Fleurette J,Delaye J

    更新日期:1984-10-01 00:00:00

  • Influence of high cardiovascular risk in asymptomatic people on the duration and cost of sick leave: results of the ICARIA study.

    abstract:AIMS:We investigated the potential influence of a moderate-to-high cardiovascular (CV) risk (CVR) (defined as a Systematic COronary Risk Evaluation model, or SCORE ≥ 4%), in the absence of an established CV disease, on the duration and cost of CV and non-CV sick leave (SL) resulting from common and occupational acciden...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/eht156

    authors: Calvo-Bonacho E,Ruilope LM,Sánchez-Chaparro MA,Cerezo C,Catalina-Romero C,Martínez-Muñoz P,Banegas JR,Waeber B,Gonzalez-Quintela A,Zanchetti A

    更新日期:2014-02-01 00:00:00

  • Sudden death in cardiac sarcoidosis: an analysis of nationwide clinical and cause-of-death registries.

    abstract:AIMS:The present study was done to assess the role of sudden cardiac death (SCD) among the presenting manifestations of and fatalities from cardiac sarcoidosis (CS). METHODS AND RESULTS:We analysed altogether 351 cases of CS presenting from year 1998 through 2015 in Finland. There were 262 patients with a clinical dia...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehz428

    authors: Ekström K,Lehtonen J,Nordenswan HK,Mäyränpää MI,Räisänen-Sokolowski A,Kandolin R,Simonen P,Pietilä-Effati P,Alatalo A,Utriainen S,Rissanen TT,Haataja P,Kokkonen J,Vihinen T,Miettinen H,Kaikkonen K,Kerola T,Kupari M

    更新日期:2019-10-01 00:00:00

  • In-hospital mortality of patients with atrial arrhythmias: insights from the German-wide Helios hospital network of 161 502 patients and 34 025 arrhythmia-related procedures.

    abstract:Aims:Atrial fibrillation (AFib) and atrial flutter (AFlut) are common arrhythmias with increased use of invasive procedures. A steady re-evaluation of relevant safety endpoints is recommended and both quality management and pay-for-performance programs are evolving. Therefore, the aims of this study were (i) to investi...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehy528

    authors: König S,Ueberham L,Schuler E,Wiedemann M,Reithmann C,Seyfarth M,Sause A,Tebbenjohanns J,Schade A,Shin DI,Staudt A,Zacharzowsky U,Andrié R,Wetzel U,Neuser H,Wunderlich C,Kuhlen R,Tijssen JGP,Hindricks G,Bollmann A

    更新日期:2018-11-21 00:00:00

  • Anomalous coronary arteries coursing between the aorta and pulmonary trunk: clinical indications for coronary artery bypass.

    abstract::Coronary arteries of anomalous origin with subsequent coursing between the aorta and pulmonary trunk can cause ischaemia, infarction or sudden death. However, reports of surgical correction are sparse due to the rarity of ante-mortem diagnosis. We report two cases in which symptoms were related to anomalous origin of ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/12.7.832

    authors: Thomas D,Salloum J,Montalescot G,Drobinski G,Artigou JY,Grosgogeat Y

    更新日期:1991-07-01 00:00:00

  • Genetic counselling and testing in cardiomyopathies: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases.

    abstract::Advances in molecular genetics present new opportunities and challenges for cardiologists who manage patients and families with cardiomyopathies. The aims of this position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases are to review the general issues related to ge...

    journal_title:European heart journal

    pub_type: 共识发展会议,杂志文章

    doi:10.1093/eurheartj/ehq271

    authors: Charron P,Arad M,Arbustini E,Basso C,Bilinska Z,Elliott P,Helio T,Keren A,McKenna WJ,Monserrat L,Pankuweit S,Perrot A,Rapezzi C,Ristic A,Seggewiss H,van Langen I,Tavazzi L,European Society of Cardiology Working Group on

    更新日期:2010-11-01 00:00:00

  • Metabolic management of ischaemic heart disease.

    abstract::The present review summarizes the available information on the effects of the three major classes of antianginal agents (nitrates, calcium and beta-blockers) on myocardial energy metabolism. It also discusses the role of some new molecules (L-carnitine, trimetazidine and ranolazine) that have been proposed as an alter...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/14.suppl_g.2

    authors: Chierchia SL,Fragasso G

    更新日期:1993-11-01 00:00:00

  • Diastolic mitral annular motion in normal subjects and patients with coronary artery disease.

    abstract::The purpose of this study was to evaluate the characteristics of mitral annular motion during diastole in 28 normal subjects, 40 patients with prior myocardial infarction (MI), and 23 patients with coronary artery disease but without prior MI. Mitral annular motion during diastole was obtained from the apex by M-mode ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a061029

    authors: Ohte N,Narita H,Hashimoto T,Kobayashi K,Akita S,Fujinami T

    更新日期:1995-07-01 00:00:00

  • Clinical value of digital radiographic coronary quantification: comparison with visual assessment and coronary flow reserve.

    abstract::The value of quantitative assessment of coronary artery dimensions at the site of the most critical coronary stenosis was assessed by comparison with the correspondent reactive hyperaemia as measured by digital subtraction angiography and with the functional results. Thirty-two coronary lesions were analysed and flow ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a060056

    authors: Legrand V,Mancini GB,Le Free MT,Vogel RA

    更新日期:1992-01-01 00:00:00

  • Fibrinogen predicts ischaemic stroke and advanced atherosclerosis but not echolucent, rupture-prone carotid plaques: the Copenhagen City Heart Study.

    abstract:AIMS:Whether the association between fibrinogen and cardiovascular events reflects an association with advanced atherosclerosis in general, or rupture-prone plaques in particular, is unclear. We examined whether fibrinogen predicts incidence of ischaemic stroke, advanced atherosclerosis (measured as carotid artery sten...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1016/s0195-668x(02)00467-0

    authors: Kofoed SC,Wittrup HH,Sillesen H,Nordestgaard BG

    更新日期:2003-03-01 00:00:00

  • Transoesophageal echocardiography for definitive diagnosis of haemodynamically significant pulmonary embolism.

    abstract::Transesophageal echocardiographic evaluation of right and left pulmonary arteries, up to the origin of their lobar branches, was prospectively performed with a single plane probe in 32 consecutive patients (18 M, 14 F, aged 55.5 +/- 14.6, from 32 to 80 years) with clinical or echocardiographic suspicion of pulmonary e...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a060947

    authors: Pruszczyk P,Torbicki A,Kuch-Wocial A,Chlebus M,Miśkiewicz ZC,Jedrusik P

    更新日期:1995-04-01 00:00:00

  • First month course of left ventricular asynergy after intracoronary thrombolysis in acute myocardial infarction. A longitudinal echocardiographic study.

    abstract::Can intracoronary thrombolytic therapy (ITT) reduce the infarct size and improve regional and global left ventricular function and if so how long after recanalization does this improvement develop? 42 patients were treated with ITT, of whom 25 showed successful recanalization (group A) and 17 had persistent occlusion ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a061937

    authors: Widimský P,Cervenka V,Gregor P,Vísek V,Sládková T,Dvorák J,Hrdlicka S

    更新日期:1985-09-01 00:00:00

  • Spectral mapping of the electrocardiogram with Fourier transform for identification of patients with sustained ventricular tachycardia and coronary artery disease.

    abstract::In time domain analysis, detection of late potentials is limited by high pass filtering, noise interference and the necessity to exclude patients with bundle branch block. We therefore used frequency analysis with Fourier transform of multiple segments of the surface electrocardiogram (25 segments, size 80 ms, time sh...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a059488

    authors: Haberl R,Jilge G,Pulter R,Steinbeck G

    更新日期:1989-04-01 00:00:00

  • Combined aortic, mitral and tricuspid surgery: results in 78 patients.

    abstract::Between 1968 and 1984, 78 patients (mean age 43, range 14 to 65 years) underwent combined aortic, mitral and tricuspid surgery (22 triple valve replacements, 56 aortic valve replacements with tricuspid conservative surgery and mitral valve replacement (N = 48), or commissuroplasty (N = 8). Pre-operative consequences o...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a062305

    authors: Michel PL,Houdart E,Ghanem G,Badaoui G,Hage A,Acar J

    更新日期:1987-05-01 00:00:00