Inflammatory biomarkers, physical activity, waist circumference, and risk of future coronary heart disease in healthy men and women.

abstract：:A previously described nitroglycerin-induced heparin resistance could not be verified by in-vitro experiments or in a randomized, double-blind, crossover trial in healthy volunteers. A clinically relevant attenuation of the anticoagulant effect of a heparin bolus (40 U.kg-1) by a concomitant infusion of nitroglycerin ...

journal_title：European heart journal

authors： Schoenenberger RA,Ménat L,Weiss P,Marbet GA,Ritz R

更新日期：1992-03-01 00:00:00

abstract：:Experience accumulated from several large trials strongly suggests that beta-blockers should be used for the management of chronic heart failure[87]. It is appropriate to add beta-blockade to conventional therapy such as diuretics, ACE inhibitors and digoxin, as this was the approach used in the major trials. It is ap...

journal_title：European heart journal

authors： Cleland JG,Bristow MR,Erdmann E,Remme WJ,Swedberg K,Waagstein F

更新日期：1996-11-01 00:00:00

abstract：:The resting and exertional haemodynamic effects of acute and chronic discontinuous (one tablet every 6 h) treatment with 5 mg of buccal nitroglycerin (BN) have been assessed in nine postinfarction heart failure patients. At rest, pulmonary artery (PAP), pulmonary wedge (PWP), and right atrial pressures (RAP) were redu...

journal_title：European heart journal

authors： Opasich C,Riccardi G,Febo O,Tramarin R,Lepore AM,Luca C,Cobelli F,Specchia G

更新日期：1988-03-01 00:00:00

abstract：AIMS:Matrix metalloproteinase-1 (MMP-1), a proteolytic enzyme able to degrade types I and III collagens, is present in atherosclerotic lesions but absent from the normal blood vessel wall. The recent observation that, in a transgenic mouse model, MMP-1 gene expression slows the development and progression of atheroscle...

journal_title：European heart journal

authors： Ye S,Gale CR,Martyn CN

更新日期：2003-09-01 00:00:00

abstract：AIMS:The purpose of this study was to develop a practical risk score to predict poor neurological outcome after out-of-hospital cardiac arrest (OOHCA) for use on arrival to a Heart Attack Centre. METHODS AND RESULTS:From May 2012 to December 2017, 1055 patients had OOHCA in our region, of whom 373 patients were includ...

journal_title：European heart journal

authors： Pareek N,Kordis P,Beckley-Hoelscher N,Pimenta D,Kocjancic ST,Jazbec A,Nevett J,Fothergill R,Kalra S,Lockie T,Shah AM,Byrne J,Noc M,MacCarthy P

更新日期：2020-12-14 00:00:00

abstract：UNLABELLED:Left atrial spontaneous echo contrast, detected by transoesophageal echocardiography in patients with non-valvular atrial fibrillation reflects slow blood flow and is associated with an increased risk of cardio-embolism. The purpose of this study was to find echo/Doppler predictors of left atrial spontaneous...

journal_title：European heart journal

authors： Pop GA,Meeder HJ,Roelandt JR,van Oudenaarden W,Bulens C,Verweij W,Gijsbers C,van Domburg R,Koudstaal PJ

更新日期：1994-11-01 00:00:00

abstract：AIMS:To analyse whether the proportion of patients with lone atrial fibrillation engaged in chronic sport practice was higher than that observed in the general population. METHODS AND RESULTS:The records of 1160 patients, seen at the arrhythmia outpatient clinic, were reviewed. A total of 70 patients (6%) suffered lon...

journal_title：European heart journal

authors： Mont L,Sambola A,Brugada J,Vacca M,Marrugat J,Elosua R,Paré C,Azqueta M,Sanz G

更新日期：2002-03-01 00:00:00

abstract：:Non-thrombotic PE does not represent a distinct clinical syndrome. It may be due to a variety of embolic materials and result in a wide spectrum of clinical presentations, making the diagnosis difficult. With the exception of severe air and fat embolism, the haemodynamic consequences of non-thrombotic emboli are usual...

journal_title：European heart journal

authors： Torbicki A,Perrier A,Konstantinides S,Agnelli G,Galiè N,Pruszczyk P,Bengel F,Brady AJ,Ferreira D,Janssens U,Klepetko W,Mayer E,Remy-Jardin M,Bassand JP,ESC Committee for Practice Guidelines (CPG).

更新日期：2008-09-01 00:00:00

abstract：:Transient ischaemic episodes, defined as chest pain with ST segment elevation resolving in less than 15 min, have been encountered in 18 out of 130 patients during or in the 12h following percutaneous transluminal angioplasty (PTCA). During PTCA, ischaemic episodes occurred in 11 patients (8.5%) along with complete co...

journal_title：European heart journal

authors： Danchin N,Cuilliere M,Cherrier F

更新日期：1984-05-01 00:00:00

abstract：:The value of measurements of the fibrinolytic factors, tissue plasminogen activator and plasminogen activator inhibitor, for predicting death and non-fatal cardiovascular events was studied in 213 consecutive patients with angiographically documented coronary artery disease. In the course of 4-year follow-up, 47 patie...

journal_title：European heart journal

authors： Jansson JH,Nilsson TK,Olofsson BO

更新日期：1991-02-01 00:00:00

abstract：AIMS:In the dual antiplatelet therapy (DAPT) study, continued thienopyridine beyond 12 months after drug-eluting stent placement was associated with increased mortality compared with placebo. We sought to evaluate factors related to mortality in randomized patients receiving either drug-eluting or bare metal stents in ...

journal_title：European heart journal

authors： Mauri L,Elmariah S,Yeh RW,Cutlip DE,Steg PG,Windecker S,Wiviott SD,Cohen DJ,Massaro JM,D'Agostino RB Sr,Braunwald E,Kereiakes DJ,DAPT Study Investigators.

更新日期：2016-01-21 00:00:00

abstract：AIMS:We sought to assess the effect of clopidogrel on clinical events 1 year after discharge in survivors of ST-elevation myocardial infarction (STEMI) in clinical practice. METHODS AND RESULTS:We analysed data of consecutive survivors of acute STEMI and either concomitant therapy with aspirin or aspirin plus clopidog...

journal_title：European heart journal

authors： Zeymer U,Gitt AK,Jünger C,Heer T,Wienbergen H,Koeth O,Bauer T,Mark B,Zahn R,Gottwik M,Senges J,Acute COronary Syndromes (ACOS) registry investigators.

更新日期：2006-11-01 00:00:00

abstract：AIMS:Targeting interleukin-1 (IL-1) represents a novel therapeutic approach to atherosclerosis. CANTOS demonstrated the benefits of IL-1β neutralization in patients post-myocardial infarction with residual inflammatory risk. Yet, some mouse data have shown a prominent role of IL-1α rather than IL-1β in atherosclerosis,...

journal_title：European heart journal

authors： Vromman A,Ruvkun V,Shvartz E,Wojtkiewicz G,Santos Masson G,Tesmenitsky Y,Folco E,Gram H,Nahrendorf M,Swirski FK,Sukhova GK,Libby P

更新日期：2019-08-07 00:00:00

abstract：OBJECTIVE:To examine the atherogenic risk-reducing effect of bezafibrate and lovastatin. DESIGN, SETTING, PATIENTS, INTERVENTIONS:Double-blind, randomized clinical trial of male and female patients with moderate hypercholesterolaemia with or without hypertriglyceridaemia. Two months dietary treatment followed by 400 m...

journal_title：European heart journal

authors： Sinzinger H,Pirich C,Kondor P,Etti H

更新日期：1995-11-01 00:00:00

abstract：:The early termination of clinical trials, for either benefit or harm, often generates undue enthusiasm or alarm. The enhanced publicity attending early termination of a trial promotes inappropriate interpretations because of the inherent difficulty of a prompt and comprehensive data review. Furthermore, the process of...

journal_title：European heart journal

authors：

更新日期：1994-06-01 00:00:00

abstract：AIMS:This study investigated the effects of irbesartan vs. enalapril, with early vs. late treatment, on markers of inflammation and ischaemic heart disease in patients with non-ST-segment elevation acute coronary syndrome (NSTEACS). METHODS AND RESULTS:Patients hospitalized with ischaemic symptoms and evidence of NSTE...

journal_title：European heart journal

authors： Montalescot G,Drexler H,Gallo R,Pearson T,Thoenes M,Bhatt DL

更新日期：2009-11-01 00:00:00

abstract：AIMS:Aldosterone plays a crucial role in cardiovascular disease. 'Systemic' inhibition of its mineralocorticoid receptor (MR) decreases atherosclerosis by reducing inflammation and oxidative stress. Obesity, an important cardiovascular risk factor, is an inflammatory disease associated with increased plasma aldosterone...

journal_title：European heart journal

authors： Schäfer N,Lohmann C,Winnik S,van Tits LJ,Miranda MX,Vergopoulos A,Ruschitzka F,Nussberger J,Berger S,Lüscher TF,Verrey F,Matter CM

更新日期：2013-12-01 00:00:00

abstract：AIM:Few epidemiological data are available describing the sudden death of persons in their prime. This study aims to elucidate when and how sudden death occurs among employees. METHODS:A total of 196775 employees from 10 workplaces in Central Japan were surveyed for non-traumatic sudden death during 1989-1995. Demogra...

journal_title：European heart journal

authors： Kawamura T,Kondo H,Hirai M,Wakai K,Tamakoshi A,Terazawa T,Osugi S,Ohno M,Okamoto N,Tsuchida T,Ohno Y,Toyama J

更新日期：1999-03-01 00:00:00

abstract：:The non-invasive quantification of mitral and aortic regurgitation using the left-to-right stroke count ratio (SCR) calculated with gated equilibrium radionuclide ventriculography (RNV), is affected by the overlap of atria and ventricles and the consequent difficult definition of the ventricular regions of interest (R...

journal_title：European heart journal

authors： Sciagrà R,Voth E,Tebbe U,Schicha H,Neuhaus KL

更新日期：1987-10-01 00:00:00

abstract：:The Alliance for Biomedical Research in Europe, co-founded by the European Society of Cardiology, has persuaded the European Parliament to move towards European Union-wide means of better directing and coordinating biomedical research, from the laboratory bench to the marketplace. ...

journal_title：European heart journal

authors： Shurlock B

更新日期：2014-04-01 00:00:00

abstract：Aims:Inhalation of nitric oxide (iNO) during myocardial ischaemia and after reperfusion confers cardioprotection in preclinical studies via enhanced cyclic guanosine monophosphate (cGMP) signalling. We tested whether iNO reduces reperfusion injury in patients with ST-elevation myocardial infarction (STEMI; NCT01398384)...

journal_title：European heart journal

authors： Janssens SP,Bogaert J,Zalewski J,Toth A,Adriaenssens T,Belmans A,Bennett J,Claus P,Desmet W,Dubois C,Goetschalckx K,Sinnaeve P,Vandenberghe K,Vermeersch P,Lux A,Szelid Z,Durak M,Lech P,Zmudka K,Pokreisz P,Vranckx

更新日期：2018-08-01 00:00:00

abstract：AIMS:Treatment of atrial fibrillation remains a major clinical challenge owing to the limited efficacy and safety of anti-arrhythmic drugs, particularly in patients with structural heart disease. METHODS AND RESULTS:To evaluate the efficacy of azimilide, a new class III anti-arrhythmic drug, we studied 658 patients wi...

journal_title：European heart journal

authors： Lombardi F,Borggrefe M,Ruzyllo W,Lüderitz B,A-COMET-II Investigators.

更新日期：2006-09-01 00:00:00

abstract：AIM:A genetic variant (rs20417) of the PTGS2 gene, encoding for COX-2, has been associated with decreased COX-2 activity and a decreased risk of cardiovascular disease (CVD). However, this genetic association and the role of COX-2 in CVD remain controversial. METHODS AND RESULTS:The association of rs20417 with CVD was...

journal_title：European heart journal

authors： Ross S,Eikelboom J,Anand SS,Eriksson N,Gerstein HC,Mehta S,Connolly SJ,Rose L,Ridker PM,Wallentin L,Chasman DI,Yusuf S,Paré G

更新日期：2014-09-01 00:00:00

abstract：AIMS:Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a key regulator of extracellular matrix degradation. We examined relations of plasma total TIMP-1 to cardiovascular risk factors and echocardiographic left ventricular (LV) structure and function in a community-based sample. METHODS AND RESULTS:We studied 1069 ...

journal_title：European heart journal

authors： Sundström J,Evans JC,Benjamin EJ,Levy D,Larson MG,Sawyer DB,Siwik DA,Colucci WS,Wilson PW,Vasan RS

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Patients with univentricular hearts have decreased exercise tolerance and may demonstrate exertional dyspnoea. It is not known if chronic hypoxaemia exacerbates exercise intolerance and contributes to symptomatic limitation. The extent to which surgical correction of a right-to-left shunt by a Fontan-type pr...

journal_title：European heart journal

authors： Iserin L,Chua TP,Chambers J,Coats AJ,Somerville J

更新日期：1997-08-01 00:00:00

abstract：:Cardiac hypertrophy was induced in rats either by isoprenaline treatment or by experimental abdominal aortic stenosis. In both models, the UTP content increased in the hypertrophying heart, while the ATP level remained depressed. The rate of net synthesis of uracil nucleotides, estimated by phosphate incorporation int...

journal_title：European heart journal

authors： Rossi A,Aussedat J,Olivarès J,Ray A,Verdys M

更新日期：1984-12-01 00:00:00

abstract：:In order to compare different criteria for the definition of late potentials in patients after myocardial infarction, three signal averaged ECG variables, duration of the signal-averaged QRS complex (QRS), root-mean-square voltage of the terminal 40 ms (RMS-40), and the duration of low amplitude signals less than 40 m...

journal_title：European heart journal

authors： Malik M,Odemuyiwa O,Poloniecki J,Kulakowski P,Farrell T,Staunton A,Camm AJ

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Maximal hyperaemia is paramount in the diagnosis of patients with coronary artery disease. However in these patients, enhanced alpha-adrenergic microvascular vasoconstriction may preclude adenosine to induce maximal hyperaemia. AIM:To assess the presence and the clinical relevance of residual microvascular ...

journal_title：European heart journal

authors： Barbato E,Bartunek J,Aarnoudse W,Vanderheyden M,Staelens F,Wijns W,Heyndrickx GR,Pijls NH,De Bruyne B

更新日期：2004-11-01 00:00:00

abstract：AIMS:Previous trials that investigated cell therapy as an adjunctive therapy after acute myocardial infarction (AMI) have shown conflicting results. We designed a randomized controlled trial to determine the effect of intracoronary infusion of mononuclear cells from bone marrow (BM) or peripheral blood in patients with...

journal_title：European heart journal

authors： Hirsch A,Nijveldt R,van der Vleuten PA,Tijssen JG,van der Giessen WJ,Tio RA,Waltenberger J,ten Berg JM,Doevendans PA,Aengevaeren WR,Zwaginga JJ,Biemond BJ,van Rossum AC,Piek JJ,Zijlstra F,HEBE Investigators.

更新日期：2011-07-01 00:00:00

abstract：AIMS:Anaemia is often observed in patients with chronic heart failure (CHF), and it may be associated with a worse prognosis. Aim of this study was to identify the individual mechanisms of anaemia in CHF patients. METHODS AND RESULTS:One hundred and forty-eight consecutive patients with haemoglobin concentration <13 g...

journal_title：European heart journal

authors： Opasich C,Cazzola M,Scelsi L,De Feo S,Bosimini E,Lagioia R,Febo O,Ferrari R,Fucili A,Moratti R,Tramarin R,Tavazzi L

更新日期：2005-11-01 00:00:00