Another step on the road to a European Council for Health Research.

abstract：AIMS:Aortic aneurysm/dissection (AAD) is a life-threatening disorder lacking effective pharmacotherapeutic remedies. Aldehyde dehydrogenase 2 (ALDH2) polymorphism is tied with various risk factors for AAD including hypertension, atherosclerosis, and hypercholesterolaemia although direct correlation between the two rema...

journal_title：European heart journal

authors： Yang K,Ren J,Li X,Wang Z,Xue L,Cui S,Sang W,Xu T,Zhang J,Yu J,Liu Z,Shang H,Pang J,Huang X,Chen Y,Xu F

更新日期：2020-07-07 00:00:00

abstract：:Three different bradycardic agents, alinidine, AQ-A39 and UL-FS49 increase the intrinsic cycle length of the isolated SA node preparation of the rabbit. This increase is mainly caused by a decrease in rate of diastolic depolarization. One of these agents, alinidine, was used to study the underlying ionic mechanism of ...

journal_title：European heart journal

authors： van Ginneken AC,Bouman LN,Jongsma HJ,Duivenvoorden JJ,Opthof T,Giles WR

更新日期：1987-12-01 00:00:00

abstract：AIMS:This study evaluated the predictive value of NT-proBNP for patients with diabetes mellitus and compared the prognostic aptitude of this neurohumoral marker to traditional markers of cardiovascular events. METHODS AND RESULTS:A prospective observational study was conducted in 631 diabetic patients. The composite e...

journal_title：European heart journal

authors： Huelsmann M,Neuhold S,Strunk G,Moertl D,Berger R,Prager R,Abrahamian H,Riedl M,Pacher R,Luger A,Clodi M

更新日期：2008-09-01 00:00:00

abstract：AIMS:Valve compliance might determine the onset of symptoms better than resting measures of aortic stenosis. This study compared valve compliance measured by dobutamine stress echocardiography with resting haemodynamic variables against the end-point of symptoms at low workload during exercise testing. METHODS AND RES...

journal_title：European heart journal

authors： Das P,Rimington H,Smeeton N,Chambers J

更新日期：2003-07-01 00:00:00

abstract：:Aims Abciximab has previously been shown to enhance thrombolysis and improve myocardial perfusion when combined with reduced doses of alteplase. The purpose of the reteplase phase of TIMI 14 was to evaluate the effects of abciximab when used in combination with a reduced dose of reteplase for ST-elevation myocardial i...

journal_title：European heart journal

authors： Antman EM,Gibson CM,de Lemos JA,Giugliano RP,McCabe CH,Coussement P,Menown I,Nienaber CA,Rehders TC,Frey MJ,Van der Wieken R,Andresen D,Scherer J,Anderson K,Van de Werf F,Braunwald E

更新日期：2000-12-01 00:00:00

abstract：:A recent report of the EuroHeart project has shown that women are still underrepresented in many cardiovascular clinical trials, while important gender differences are present within most areas of heart disease. As the burden of cardiovascular disease is increasing in middle-aged women relative to men, a more profound...

journal_title：European heart journal

authors： Maas AH,van der Schouw YT,Regitz-Zagrosek V,Swahn E,Appelman YE,Pasterkamp G,Ten Cate H,Nilsson PM,Huisman MV,Stam HC,Eizema K,Stramba-Badiale M

更新日期：2011-06-01 00:00:00

abstract：:The 18 month mortality rate in 2180 patients excluded from the Danish Verapamil Infarction Trail II (DAVIT II) was 25.6%. In non-consenters (n = 368) this was 15.0% compared with 13.85 in 897 placebo-treated patients (hazard ratio 1.09 [P = 0.60] when adjusting for sex and age). The increased mortality rate in exclude...

journal_title：European heart journal

authors： Madsen JK,Hansen JF

更新日期：1993-03-01 00:00:00

abstract：:The understanding of atrial fibrillation (AF) evolved from a sole rhythm disturbance towards the complex concept of a cardiomyopathy based on arrhythmia substrates. There is evidence that atrial fibrosis can be visualized using late gadolinium enhancement cardiac magnetic resonance imaging and that it is a powerful pr...

journal_title：European heart journal

authors： Sohns C,Marrouche NF

更新日期：2020-03-07 00:00:00

abstract：:Hypokalaemia commonly occurs in acute myocardial infarction (AMI) and may be caused by elevated serum levels of adrenaline, allegedly by beta 2-adrenergic mediated influx of potassium (K) into cells. We investigated the effect on serum K of intravenous acebutolol (a relatively beta 1-selective agent) in 50 patients wi...

journal_title：European heart journal

authors： Jardine RM,Obel IW,Smith AM

更新日期：1986-02-01 00:00:00

abstract：:In this study, two patterns of regional contract on of the left ventricle have been studied: endocardial motion and wall thickening, in order to check which of these was the most affected after myocardial infarction. The clinical relevance of this comparison was to assess which parameter of the regional contraction ab...

journal_title：European heart journal

authors： Germain P,Roul G,Constantinesco A,Coulbois PM,Baruthio J,Mossard JM,Bareiss P,Sacrez A

更新日期：1996-09-01 00:00:00

abstract：AIMS:Long-term randomized comparisons of percutaneous coronary intervention (PCI) to coronary artery bypass grafting (CABG) in left main coronary (LM) disease and/or three-vessel disease (3VD) patients have been limited. This analysis compares 3-year outcomes in LM and/or 3VD patients treated with CABG or PCI with TAXU...

journal_title：European heart journal

authors： Kappetein AP,Feldman TE,Mack MJ,Morice MC,Holmes DR,Ståhle E,Dawkins KD,Mohr FW,Serruys PW,Colombo A

更新日期：2011-09-01 00:00:00

abstract：:Advanced coronary artery disease (CAD), impaired left ventricular function and prolongation of the QT-interval are considered risk factors for sudden cardiac death in CAD-patients. So far, however, there are no studies investigating in detail whether there is a correlation between the QT-interval and changes in corona...

journal_title：European heart journal

authors： Krämer B,Brill M,Brühn A,Kübler W

更新日期：1986-01-01 00:00:00

abstract：AIMS:The purpose of this study was to calculate the prevalence of ectopic atrial tachycardia in a population of young asymptomatic males and to assess its natural course both in asymptomatic subjects and in symptomatic hospital patients. METHODS AND RESULTS:12-lead electrocardiograms (ECG) of 3554 consecutive males ap...

journal_title：European heart journal

authors： Poutiainen AM,Koistinen MJ,Airaksinen KE,Hartikainen EK,Kettunen RV,Karjalainen JE,Huikuri HV

更新日期：1999-05-01 00:00:00

abstract：AIMS:Although regular physical activity has beneficial cardiovascular effects, exercise can trigger an acute cardiac event. We aimed to determine the incidence and prognosis of exercise-related out-of-hospital cardiac arrest (OHCA) in the general population. METHODS AND RESULTS:We prospectively collected all OHCAs in ...

journal_title：European heart journal

authors： Berdowski J,de Beus MF,Blom M,Bardai A,Bots ML,Doevendans PA,Grobbee DE,Tan HL,Tijssen JG,Koster RW,Mosterd A

更新日期：2013-12-01 00:00:00

abstract：Aim:Hypertrophic cardiomyopathy (HCM) exhibits genetic heterogeneity that is dominated by variation in eight sarcomeric genes. Genetic variation in a large number of non-sarcomeric genes has also been implicated in HCM but not formally assessed. Here we used very large case and control cohorts to determine the extent t...

journal_title：European heart journal

authors： Walsh R,Buchan R,Wilk A,John S,Felkin LE,Thomson KL,Chiaw TH,Loong CCW,Pua CJ,Raphael C,Prasad S,Barton PJ,Funke B,Watkins H,Ware JS,Cook SA

更新日期：2017-12-07 00:00:00

abstract：:Thrombolytic treatment efficacy is greater when the delay between onset of pain and treatment is short. One way to shorten this delay is to give treatment at home, but one cannot recommend this technique if it has not been demonstrated first, that pre-hospital thrombolysis is feasible and safe, and second, that it is ...

journal_title：European heart journal

authors： Castaigne AD,Hervé C,Duval-Moulin AM,Gaillard M,Dubois-Randé JL,Lellouche D

更新日期：1990-08-01 00:00:00

abstract：:It is not yet clear whether 99mTc-methoxyisobutyl-isonitrile (MIBI)-uptake is a reliable indicator of myocardial viability, and a threshold value, differentiating viable from scarred myocardium, in comparison to a morphological and functional standard of reference has not been defined. MIBI-uptake was quantified in 80...

journal_title：European heart journal

authors： Baer FM,Smolarz K,Theissen P,Voth E,Schicha H,Sechtem U

更新日期：1994-01-01 00:00:00

abstract：AIMS:Assessment of N-terminal brain natriuretic peptide (NT-BNP) as a screening tool for heart failure in patients with a permanent pacemaker. METHODS AND RESULTS:Consecutive patients undergoing a routine permanent pacemaker assessment were enrolled. Patients underwent medical history and examination, echocardiography...

journal_title：European heart journal

authors： Thackray SD,Witte K,Ghosh J,Nikitin N,Anderson A,Rigby A,Goode K,Clark AL,Cleland JG

更新日期：2006-02-01 00:00:00

abstract：AIMS:Previous studies have suggested that a high body mass index (BMI) is associated with an improved outcome in congestive heart failure (CHF). However, the studies addressing this problem have not included enough patients with non-systolic heart failure to evaluate how left ventricular systolic function interacts wit...

journal_title：European heart journal

authors： Gustafsson F,Kragelund CB,Torp-Pedersen C,Seibaek M,Burchardt H,Akkan D,Thune JJ,Køber L,DIAMOND study group.

更新日期：2005-01-01 00:00:00

abstract：Aims:To characterize the relationship between blood pressure (BP) or heart rate and mortality and morbidity in chronic obstructive pulmonary disease (COPD). Methods and results:We performed post hoc analysis of baseline BP or heart rate and all-cause mortality and cardiovascular events in the SUMMIT trial. SUMMIT was ...

journal_title：European heart journal

authors： Byrd JB,Newby DE,Anderson JA,Calverley PMA,Celli BR,Cowans NJ,Crim C,Martinez FJ,Vestbo J,Yates J,Brook RD,SUMMIT Investigators.

更新日期：2018-09-01 00:00:00

abstract：AIMS:The extent to which hospital and geographic characteristics influence the time course of uptake of evidence from key clinical trials and practice guidelines is unknown. The gap between evidence and practice is well recognized but the factors influencing this disjunction, and the extent to which such factors are mo...

journal_title：European heart journal

authors： Fox KA,Goodman SG,Anderson FA Jr,Granger CB,Moscucci M,Flather MD,Spencer F,Budaj A,Dabbous OH,Gore JM,GRACE Investigators.

更新日期：2003-08-01 00:00:00

abstract：:A look back on the history of the European Society of Cardiology which officially came into existence in 1950. ...

journal_title：European heart journal

authors：

更新日期：2015-07-21 00:00:00

abstract：AIMS:Thrombin plays a key role in the clinical syndrome of unstable angina. We investigated the safety and efficacy of five dose levels of efegatran sulphate, a direct thrombin inhibitor, compared to heparin in patients with unstable angina. METHODS:Four hundred and thirty-two patients with unstable angina were enroll...

journal_title：European heart journal

authors： Klootwijk P,Lenderink T,Meij S,Boersma H,Melkert R,Umans VA,Stibbe J,Müller EJ,Poortermans KJ,Deckers JW,Simoons ML

更新日期：1999-08-01 00:00:00

abstract：:Several targets for heart failure therapy may be met through different mechanisms which are not necessarily associated. In the Australia/New Zealand Heart Failure Research Collaborative Group Study, patients with chronic stable heart failure of ischaemic aetiology on treatment including ACE inhibitors were randomized ...

journal_title：European heart journal

authors： Sharpe N,Doughty RN

更新日期：1998-02-01 00:00:00

abstract：:After years of stagnant finances for research, moves are under way to increase research funds in Europe. ...

journal_title：European heart journal

authors： Smith U,Sipido K,Dive C,Nicod L

更新日期：2011-09-01 00:00:00

abstract：:In single vessel disease angioplasty can replace surgery in the majority of patients. In cases of recurrence at the site of angioplasty or in the case of progression elsewhere, a second intervention can be performed. Thus, in the majority of patients surgery can be replaced; in the minority it can be delayed. In patie...

journal_title：European heart journal

authors： Kaltenbach M

更新日期：1987-09-01 00:00:00

abstract：AIMS:We explored the association between exposure to environmental tobacco smoke (ETS) and various cardiometabolic biomarkers in 10-year-old children. METHODS AND RESULTS:A population-based cross-sectional study was carried out. Data on ETS exposure and potential confounders were collected by parental questionnaire. A...

journal_title：European heart journal

authors： Nagel G,Arnold FJ,Wilhelm M,Link B,Zoellner I,Koenig W

更新日期：2009-08-01 00:00:00

abstract：:Late potentials detected by the signal-averaged ECG (SAECG) identify post-infarction patients at risk from sustained ventricular tachycardia (VT) and sudden death. Hypertrophic cardiomyopathy (HCM) is also associated with increased risk of sudden death. In adults, episodes of non-sustained VT on ambulatory ECG monitor...

journal_title：European heart journal

authors： Kulakowski P,Counihan PJ,Camm AJ,McKenna WJ

更新日期：1993-07-01 00:00:00

abstract：:After single chamber atrial pacemaker implantation, serial electrophysiologic studies were performed noninvasively at intervals of 3 months over a total period of 3 years in 24 patients with symptomatic sinus node dysfunction. All patients underwent invasive electrophysiologic studies before pacemaker implantation and...

journal_title：European heart journal

authors： van Mechelen R,Segers A,Hagemeijer F

更新日期：1984-08-01 00:00:00

abstract：AIMS:To evaluate the predictive value of high sensitivity (hs) C-reactive protein levels on long-term survival in patients with ST-elevation myocardial infarction (STEMI) treated with primary PCI. METHODS AND RESULTS:We conducted a retrospective analysis of 758 STEMI patients (from January 2003 to December 2005), with...

journal_title：European heart journal

authors： Ortolani P,Marzocchi A,Marrozzini C,Palmerini T,Saia F,Taglieri N,Baldazzi F,Silenzi S,Bacchi-Reggiani ML,Guastaroba P,Grilli R,Branzi A

更新日期：2008-05-01 00:00:00