Atrial fibrillation and cardiac fibrosis.

Abstract:

:The understanding of atrial fibrillation (AF) evolved from a sole rhythm disturbance towards the complex concept of a cardiomyopathy based on arrhythmia substrates. There is evidence that atrial fibrosis can be visualized using late gadolinium enhancement cardiac magnetic resonance imaging and that it is a powerful predictor for the outcome of AF interventions. However, a strategy of an individual and fibrosis guided management of AF looks promising but results from prospective multicentre trials are pending. This review gives an overview about the relationship between cardiac fibrosis and AF focusing on translational aspects, clinical observations, and fibrosis imaging to emphasize the concept of personalized paths in AF management taking into account the individual amount and distribution of fibrosis.

journal_name

Eur Heart J

journal_title

European heart journal

authors

Sohns C,Marrouche NF

doi

10.1093/eurheartj/ehz786

subject

Has Abstract

pub_date

2020-03-07 00:00:00

pages

1123-1131

issue

10

eissn

0195-668X

issn

1522-9645

pii

5622908

journal_volume

41

pub_type

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