Exercise-related out-of-hospital cardiac arrest in the general population: incidence and prognosis.

Abstract:

AIMS:Although regular physical activity has beneficial cardiovascular effects, exercise can trigger an acute cardiac event. We aimed to determine the incidence and prognosis of exercise-related out-of-hospital cardiac arrest (OHCA) in the general population. METHODS AND RESULTS:We prospectively collected all OHCAs in persons aged 10-90 years from January 2006 to January 2009 in the Dutch province North Holland. The relation between exercise during or within 1 h before OHCA and outcome was analysed using multivariable logistic regression, adjusted for age, gender, location, bystander witness, bystander cardiopulmonary resuscitation (CPR), automated external defibrillator (AED) use, initial rhythm, and Emergency Medical System response time. Of 2524 OHCAs, 143 (5.7%) were exercise related (7 ≤35 years, 93% men). Exercise-related OHCA incidence was 2.1 per 100 000 person-years overall and 0.3 per 100 000 person-years in those ≤35 years. Survival after exercise-related OHCA was distinctly better than after non-exercise related OHCA (46.2 vs. 17.2%) [unadjusted odds ratio (OR) 4.12; 95%CI 2.92-5.82; P < 0.001], even after adjustment for abovementioned variables (OR 2.63; 95%CI, 1.23-5.54; P = 0.01). In the 69 victims aged ≤35 years, exercise was not associated with better survival: 14.3 vs. 17.7% in non-exercise-related OHCA (OR 0.77; 95%CI 0.08-7.08; P = 0.82). CONCLUSION:Exercise-related OHCA has a low incidence, particularly in the young. Cardiac arrests occurring during or shortly after exercise carry a markedly better prognosis than non-exercise-related arrests in persons >35 years. This study establishes the favourable outcome of exercise-related OHCA and should have direct implications for public health programs to prevent exercise-related sudden death.

journal_name

Eur Heart J

journal_title

European heart journal

authors

Berdowski J,de Beus MF,Blom M,Bardai A,Bots ML,Doevendans PA,Grobbee DE,Tan HL,Tijssen JG,Koster RW,Mosterd A

doi

10.1093/eurheartj/eht401

subject

Has Abstract

pub_date

2013-12-01 00:00:00

pages

3616-23

issue

47

eissn

0195-668X

issn

1522-9645

pii

eht401

journal_volume

34

pub_type

杂志文章
  • Transoesophageal electrophysiological evaluation of paediatric patients with Wolff-Parkinson-White syndrome.

    abstract::Forty-one consecutive children with the Wolff-Parkinson-White (1-15 years: mean 8 years), 22 symptomatic [including 20 with supraventricular tachycardia (SVT) and one with ventricular fibrillation (VF) episode--Group A) and 19 asymptomatic (Group B)], underwent transoesophageal electrophysiological examination. The me...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a060150

    authors: Vignati G,Mauri L,Lunati M,Gasparini M,Figini A

    更新日期:1992-02-01 00:00:00

  • Prevalence and significance of an abnormal exercise ECG in asymptomatic males. Outcome of thallium myocardial scintigraphy.

    abstract::During a 3-year period 2500 asymptomatic male aviators were screened routinely for coronary artery disease by maximal bicycle exercise testing. In 55 cases (2.1%) the exercise ECG was abnormal (40 subjects exhibited ST depression, 14 ventricular ectopic activity and in one subject both abnormalities were observed). Fu...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/12.7.766

    authors: Pedersen F,Sandøe E,Laerkeborg A

    更新日期:1991-07-01 00:00:00

  • Acute vascular toxicity after combination chemotherapy with cisplatin, vinblastine, and bleomycin for testicular cancer.

    abstract::Twenty-one consecutive patients with testicular cancer treated with bleomycin, vinblastine, and cisplatin (PVB) were evaluated for acute vascular ischaemic events during chemotherapy. Angina pectoris occurred in 8/21 (38%) patients, a median 5.6 weeks after initiation of chemotherapy and persisted for 2-7 days. Raynau...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a062542

    authors: Stefenelli T,Kuzmits R,Ulrich W,Glogar D

    更新日期:1988-05-01 00:00:00

  • Myocardial perfusion imaging with positron emission tomography and single photon emission computed tomography: frequency and causes of disparate results.

    abstract::The purpose of this study was to compare rubidium-82 PET with thallium-201 SPECT imaging in 150 patients. Both techniques followed a single dipyridamole-handgrip stress, and images were displayed using the same 3-dimensional format and quantitative colour scale. Coronary arteriography was employed to assign the correc...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a059838

    authors: Marwick TH,Go RT,MacIntyre WJ,Saha GB,Underwood DA

    更新日期:1991-10-01 00:00:00

  • Inflammatory biomarkers, physical activity, waist circumference, and risk of future coronary heart disease in healthy men and women.

    abstract:AIMS:The aim of this study was to determine the contribution of physical activity and abdominal obesity to the variation in inflammatory biomarkers and incident coronary heart disease (CHD) in a European population. METHODS AND RESULTS:In a prospective case-control study nested in the European Prospective Investigatio...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehp010

    authors: Rana JS,Arsenault BJ,Després JP,Côté M,Talmud PJ,Ninio E,Wouter Jukema J,Wareham NJ,Kastelein JJ,Khaw KT,Boekholdt SM

    更新日期:2011-02-01 00:00:00

  • Comparison between abnormalities in segmental endocardial motion and abnormalities in segmental wall thickening after anterior myocardial infarction. A cine-magnetic resonance study.

    abstract::In this study, two patterns of regional contract on of the left ventricle have been studied: endocardial motion and wall thickening, in order to check which of these was the most affected after myocardial infarction. The clinical relevance of this comparison was to assess which parameter of the regional contraction ab...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/oxfordjournals.eurheartj.a015069

    authors: Germain P,Roul G,Constantinesco A,Coulbois PM,Baruthio J,Mossard JM,Bareiss P,Sacrez A

    更新日期:1996-09-01 00:00:00

  • Comparative study of echo- and angiocardiographically determined regional left ventricular wall motion in recent myocardial infarction.

    abstract::We have studied regional left ventricular (LV) wall motion with M-mode, cross-sectional (2D) echocardiography and LV angiography in 50 patients with a recent myocardial infarction. Regional LV wall motion was evaluated according to a 9-segment model. 2D echocardiography permitted information from all, M-mode echocardi...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a061703

    authors: Lindvall K,Hamsten A,Landou C,Szamosi A,de Faire U

    更新日期:1984-07-01 00:00:00

  • Low-density lipoprotein cholesterol targeting with pitavastatin + ezetimibe for patients with acute coronary syndrome and dyslipidaemia: the HIJ-PROPER study, a prospective, open-label, randomized trial.

    abstract:Aims:To elucidate the effects of intensive LDL-C lowering treatment with a standard dose of statin and ezetimibe in patients with dyslipidaemia and high risk of coronary events, targeting LDL-C less than 70 mg/dL (1.8 mmol/L), compared with standard LDL-C lowering lipid monotherapy targeting less than 100 mg/dL (2.6 mm...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/ehx162

    authors: Hagiwara N,Kawada-Watanabe E,Koyanagi R,Arashi H,Yamaguchi J,Nakao K,Tobaru T,Tanaka H,Oka T,Endoh Y,Saito K,Uchida T,Matsui K,Ogawa H

    更新日期:2017-08-01 00:00:00

  • Substantial between-hospital variation in outcome following first emergency admission for heart failure.

    abstract:BACKGROUND:Following hospitalization with a range of cardiovascular disorders, substantial variation has been noted in clinical outcome, both between and within countries. OBJECTIVES:To examine the variation, between hospitals, in the clinical outcomes of death and readmission following hospitalization with heart fail...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1053/euhj.2001.2890

    authors: Stewart S,Demers C,Murdoch DR,McIntyre K,MacLeod ME,Kendrick S,Capewell S,McMurray JJ

    更新日期:2002-04-01 00:00:00

  • Rate of telomere shortening and cardiovascular damage: a longitudinal study in the 1946 British Birth Cohort.

    abstract:AIM:Cross-sectional studies reported associations between short leucocyte telomere length (LTL) and measures of vascular and cardiac damage. However, the contribution of LTL dynamics to the age-related process of cardiovascular (CV) remodelling remains unknown. In this study, we explored whether the rate of LTL shorten...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehu226

    authors: Masi S,D'Aiuto F,Martin-Ruiz C,Kahn T,Wong A,Ghosh AK,Whincup P,Kuh D,Hughes A,von Zglinicki T,Hardy R,Deanfield JE,NSHD scientific and data collection teams.

    更新日期:2014-12-07 00:00:00

  • The long-term impact of the angiotensin-converting enzyme inhibitor trandolapril on mortality and hospital admissions in patients with left ventricular dysfunction after a myocardial infarction: follow-up to 12 years.

    abstract:AIMS:To investigate the long-term benefits of treatment with angiotensin-converting enzyme (ACE)-inhibitors in patients with myocardial infarction (MI) and left ventricular dysfunction (LVD). METHODS AND RESULTS:In the trandolapril cardiac evaluation (TRACE) study, 1749 patients with LVD (ejection fraction< or =35%) w...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/eurheartj/ehi021

    authors: Buch P,Rasmussen S,Abildstrom SZ,Køber L,Carlsen J,Torp-Pedersen C,TRACE investigators.

    更新日期:2005-01-01 00:00:00

  • Serial electrophysiologic studies after single chamber atrial pacemaker implantation in patients with symptomatic sinus node dysfunction.

    abstract::After single chamber atrial pacemaker implantation, serial electrophysiologic studies were performed noninvasively at intervals of 3 months over a total period of 3 years in 24 patients with symptomatic sinus node dysfunction. All patients underwent invasive electrophysiologic studies before pacemaker implantation and...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a061719

    authors: van Mechelen R,Segers A,Hagemeijer F

    更新日期:1984-08-01 00:00:00

  • Does implementation of the European guidelines based on the SCORE model double the number of Norwegian adults who need cardiovascular drugs for primary prevention? The Tromsø study 2001.

    abstract:AIMS:To study the implications of European guidelines on the use of antihypertensives and/or lipid-lowering drugs (LLDs) for primary prevention in a Norwegian population. METHODS AND RESULTS:The Tromsø study is a population-based study in the municipality Tromsø, Norway (from 1974 to till now). This analysis includes ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehi556

    authors: Hartz I,Njølstad I,Eggen AE

    更新日期:2005-12-01 00:00:00

  • Haemodynamically irrelevant pericardial effusion is associated with increased mortality in patients with chronic heart failure.

    abstract:AIMS:Pericardial effusion (PE) is a common finding in cardiac patients with chronic heart failure. The prognostic relevance of a small, haemodynamically non-compromising PE in such patients, however, remains to be determined. METHODS AND RESULTS:All patients referred to our heart failure clinic and having a baseline e...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/eht006

    authors: Fröhlich GM,Keller P,Schmid F,Wolfrum M,Osranek M,Falk C,Noll G,Enseleit F,Reinthaler M,Meier P,Lüscher TF,Ruschitzka F,Tanner FC

    更新日期:2013-05-01 00:00:00

  • Adipose dysplasia of the right ventricle: is endomyocardial biopsy useful?

    abstract::Right ventricular dysplasia (RVD) is a cardiac anomaly characterized by replacement of right ventricular myocardium by adipose and fibrous tissue that was first described at autopsy, and is now being recognized pre-mortem. Sudden death and ventricular arrhythmias are the most common clinical manifestation of the condi...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/10.suppl_d.84

    authors: Strain J

    更新日期:1989-09-01 00:00:00

  • Heterogeneity of endothelial dysfunction in hypertension.

    abstract::The endothelium may play a role as a target and mediator of hypertension. Due to its anatomical position, it is very exposed to mechanical forces; as a source of vasoactive material it may participate in increasing peripheral vascular resistance and in promoting local ischaemia in the heart and brain. Morphological an...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/13.suppl_d.50

    authors: Lüscher TF

    更新日期:1992-09-01 00:00:00

  • Randomized trial to determine the effect of nebivolol on mortality and cardiovascular hospital admission in elderly patients with heart failure (SENIORS).

    abstract:AIMS:Large randomized trials have shown that beta-blockers reduce mortality and hospital admissions in patients with heart failure. The effects of beta-blockers in elderly patients with a broad range of left ventricular ejection fraction are uncertain. The SENIORS study was performed to assess effects of the beta-block...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/ehi115

    authors: Flather MD,Shibata MC,Coats AJ,Van Veldhuisen DJ,Parkhomenko A,Borbola J,Cohen-Solal A,Dumitrascu D,Ferrari R,Lechat P,Soler-Soler J,Tavazzi L,Spinarova L,Toman J,Böhm M,Anker SD,Thompson SG,Poole-Wilson PA,SENIORS In

    更新日期:2005-02-01 00:00:00

  • Contraception and cardiovascular disease.

    abstract::Contraceptive counselling should begin early in females with heart disease, preferably directly after the start of menstruation. In coming to a decision about the method of contraception, the following issues should be considered: (i) the risk of pregnancy for the mother and the consequences of an unplanned pregnancy;...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/ehv141

    authors: Roos-Hesselink JW,Cornette J,Sliwa K,Pieper PG,Veldtman GR,Johnson MR

    更新日期:2015-07-14 00:00:00

  • Lipoproteins in chronic kidney disease: from bench to bedside.

    abstract::Chronic kidney disease (CKD) is associated with high cardiovascular risk. CKD patients exhibit a specific lipoprotein pattern termed 'uraemic dyslipidaemia', which is characterized by rather normal low-density lipoprotein cholesterol, low high-density lipoprotein cholesterol, and high triglyceride plasma levels. All t...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehaa1050

    authors: Speer T,Ridker PM,von Eckardstein A,Schunk SJ,Fliser D

    更新日期:2021-01-04 00:00:00

  • Non-invasive diagnosis of ischaemic heart failure using 64-slice computed tomography.

    abstract:AIMS:We evaluated the accuracy of 64-slice computed tomography (CT) to identify ischaemic aetiology of heart failure (IHF). METHODS AND RESULTS:Ninety-three consecutive patients in sinus rhythm with dilated cardiomyopathy but without suspicion of coronary artery disease (CAD) were enrolled when admitted for angiograph...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehn072

    authors: Ghostine S,Caussin C,Habis M,Habib Y,Clément C,Sigal-Cinqualbre A,Angel CY,Lancelin B,Capderou A,Paul JF

    更新日期:2008-09-01 00:00:00

  • Exercise-induced right ventricular dysfunction is associated with ventricular arrhythmias in endurance athletes.

    abstract:AIMS:Intense exercise places disproportionate strain on the right ventricle (RV) which may promote pro-arrhythmic remodelling in some athletes. RV exercise imaging may enable early identification of athletes at risk of arrhythmias. METHODS AND RESULTS:Exercise imaging was performed in 17 athletes with RV ventricular a...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehv202

    authors: La Gerche A,Claessen G,Dymarkowski S,Voigt JU,De Buck F,Vanhees L,Droogne W,Van Cleemput J,Claus P,Heidbuchel H

    更新日期:2015-08-07 00:00:00

  • The impact of cachexia on cardiorespiratory reflex control in chronic heart failure.

    abstract:BACKGROUND:The mechanism of persistent neurohormonal and cardiorespiratory reflex abnormalities in chronic heart failure remain unclear. Also, why chronic heart failure patients who develop cachexia demonstrate a particularly abnormal neurohormonal profile and have a high risk of death is not known. Impaired reflex con...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1053/euhj.1999.1525

    authors: Ponikowski P,Piepoli M,Chua TP,Banasiak W,Francis D,Anker SD,Coats AJ

    更新日期:1999-11-01 00:00:00

  • The acute effects of intravenous nisoldipine on left ventricular function within 24 h after acute myocardial infarction.

    abstract::Nisoldipine is a calcium antagonist with potent coronary vasodilating effects in patients with chronic stable angina pectoris. We studied the acute effects of nisoldipine in six patients within 24 h (mean 14 +/- 4 h) after the onset of myocardial infarction. Nisoldipine was administered as a 4.5 micrograms kg-1 intrav...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a060125

    authors: Chin JC,van der Wall EE,Manger Cats V,van der Laarse A,Blokland JA,Pauwels EJ,Bruschke AV

    更新日期:1992-12-01 00:00:00

  • The value of exercise-induced U-wave inversion on ECG chest wall mapping in the identification of individual coronary arterial lesions.

    abstract::Exercise-induced U-wave inversion on chest wall mapping was compared with coronary arteriographic findings in 160 consecutive patients who presented with chest pain suggestive of ischaemic heart disease. ECG recordings were made from 16 points on the chest wall before, during and after exercise. None of the 27 patient...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a061883

    authors: Salmasi AM,Salmasi SN,Nicolaides AN,Vecht RJ,Hendry WG,Kidner PH,Besterman EM

    更新日期:1985-05-01 00:00:00

  • An increase in sudden unexpected cardiac deaths among young Swedish orienteers during 1979-1992.

    abstract:BACKGROUND:Sixteen cases of sudden unexpected cardiac death, 15 males and one female, are known to have occurred among young Swedish orienteers from 1979 to 1992, of which seven cases occurred between 1989 and 1992. This is considered to be indicative of an increased death rate. RESULTS:Histopathological evaluation sh...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a014972

    authors: Wesslén L,Påhlson C,Lindquist O,Hjelm E,Gnarpe J,Larsson E,Baandrup U,Eriksson L,Fohlman J,Engstrand L,Linglöf T,Nyström-Rosander C,Gnarpe H,Magnius L,Rolf C,Friman G

    更新日期:1996-06-01 00:00:00

  • JACC, the Journal of the American College of Cardiology.

    abstract::Anthony N. DeMaria discusses the journal's history, its focus,and innovative ideas for Internet reading. ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:

    authors: Taylor J

    更新日期:2012-02-01 00:00:00

  • Reactive thrombocytosis and stroke following cardiopulmonary bypass surgery: case report on three patients.

    abstract::Reactive thrombocytosis following cardiopulmonary bypass surgery is generally considered to be a benign condition which is transient and does not require specific therapy. We describe three patients who developed stroke in association with reactive thrombocytosis in the late recovery period following cardiopulmonary b...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a060642

    authors: Crowley JJ,Hannigan M,Daly K

    更新日期:1994-08-01 00:00:00

  • Relation between serum N-terminal pro-brain natriuretic peptide and prognosis in patients with hypertrophic cardiomyopathy.

    abstract:AIMS:To determine the relation between serum concentrations of N-terminal pro-brain natriuretic peptide (NT-proBNP) and prognosis in patients with hypertrophic cardiomyopathy (HCM). METHODS AND RESULTS:In total, 847 patients (53 ± 15 years; 67% male) with HCM (28% with left ventricular outflow tract obstruction ≥ 30 m...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/eht070

    authors: Coats CJ,Gallagher MJ,Foley M,O'Mahony C,Critoph C,Gimeno J,Dawnay A,McKenna WJ,Elliott PM

    更新日期:2013-08-01 00:00:00

  • Time-to-treatment significantly affects the extent of ST-segment resolution and myocardial blush in patients with acute myocardial infarction treated by primary angioplasty.

    abstract:AIMS:The prognostic role of time-to-treatment in primary angioplasty is still a matter of debate. The aim of our study was to evaluate the relationship between time-to-treatment and myocardial perfusion in patients with ST-segment-elevation myocardial infarction (STEMI) treated by primary angioplasty. METHODS AND RESU...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ehj.2004.03.021

    authors: De Luca G,van 't Hof AW,de Boer MJ,Ottervanger JP,Hoorntje JC,Gosselink AT,Dambrink JH,Zijlstra F,Suryapranata H

    更新日期:2004-06-01 00:00:00

  • Therapeutic efficacy of cardiosphere-derived cells in a transgenic mouse model of non-ischaemic dilated cardiomyopathy.

    abstract:AIM:Cardiosphere-derived cells (CDCs) produce regenerative effects in the post-infarct setting. However, it is unclear whether CDCs are beneficial in non-ischaemic dilated cardiomyopathy (DCM). We tested the effects of CDC transplantation in mice with cardiac-specific Gαq overexpression, which predictably develop progr...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehu196

    authors: Aminzadeh MA,Tseliou E,Sun B,Cheng K,Malliaras K,Makkar RR,Marbán E

    更新日期:2015-03-21 00:00:00