A new Alliance: biomedical societies in Europe unite to support research.

abstract：:The early termination of clinical trials, for either benefit or harm, often generates undue enthusiasm or alarm. The enhanced publicity attending early termination of a trial promotes inappropriate interpretations because of the inherent difficulty of a prompt and comprehensive data review. Furthermore, the process of...

journal_title：European heart journal

authors：

更新日期：1994-06-01 00:00:00

abstract：:The immediate and short-term results of coronary angioplasty were analysed in 16 patients who presented with chest pain at rest associated with transient marked ST-segment elevation (greater than or equal to 0.5 mV). The number of in hospital ischaemic attacks was on average 2.8 (range 1-8). All patients had at least ...

journal_title：European heart journal

authors： de Feyter PJ,Serruys PW,van den Brand M,Soward A

更新日期：1987-06-01 00:00:00

abstract：:The non-invasive quantification of mitral and aortic regurgitation using the left-to-right stroke count ratio (SCR) calculated with gated equilibrium radionuclide ventriculography (RNV), is affected by the overlap of atria and ventricles and the consequent difficult definition of the ventricular regions of interest (R...

journal_title：European heart journal

authors： Sciagrà R,Voth E,Tebbe U,Schicha H,Neuhaus KL

更新日期：1987-10-01 00:00:00

abstract：Aims:The burden of cardiovascular disease is increasing worldwide, which has to be reflected by cardiovascular (CV) research in Europe. CardioScape, a FP7 funded project initiated by the European Society of Cardiology (ESC), identified where CV research is performed, how it is funded and by whom. It could be transforme...

journal_title：European heart journal

authors： Pries AR,Naoum A,Habazettl H,Dunkel M,Preissner R,Coats CJ,Tornada A,Orso F,Van de Werf F,Wood DA,CardioScape steering committee.,Van de Werf F,Wood DA,O'Kelly S,Craven J,Coats A,Sipido K,De Backer D,Wallentin L,Has

更新日期：2018-07-01 00:00:00

abstract：AIMS:Angiotensin-converting enzyme (ACE) inhibitors have been shown to reduce cardiovascular risk in different groups of patients. Whether these effects can be generalized to the broad group of patients with vascular disease is unknown. Therefore, we undertook a combined analysis using individual data from ADVANCE, EUR...

journal_title：European heart journal

authors： Brugts JJ,Ninomiya T,Boersma E,Remme WJ,Bertrand M,Ferrari R,Fox K,MacMahon S,Chalmers J,Simoons ML

更新日期：2009-06-01 00:00:00

abstract：:From 1978 to 1980, 260 healthy subjects, 40-79 years of age, underwent 24 h ambulatory electrocardiography in order to determine the prevalence and complexity of ventricular premature beats (VPBs) in adults without apparent heart disease. The number of types of VPBs seem in 5% or less were considered 'abnormal' and th...

journal_title：European heart journal

authors： Bjerregaard P,Sorensen KE,Molgaard H

更新日期：1991-05-01 00:00:00

abstract：AIMS:This study assessed the relationship between inflammatory mediators and indices of infarct size and left-ventricular (LV) remodelling following successful primary percutaneous coronary intervention (PCI) in patients with first time ST elevation myocardial infarction (MI). METHODS AND RESULTS:Forty-two patients ad...

journal_title：European heart journal

authors： Ørn S,Manhenke C,Ueland T,Damås JK,Mollnes TE,Edvardsen T,Aukrust P,Dickstein K

更新日期：2009-05-01 00:00:00

abstract：:To compare the blood pressure (BP) changes during a long-distance run with those during bicycle ergometry, nine normotensive and 18 hypertensive joggers were studied by means of ambulatory intra-arterial monitoring. In all subjects the ergometric test caused a progressive increase in systolic and little change in dias...

journal_title：European heart journal

authors： Palatini P,Mos L,Mormino P,Munari L,Del Torre M,Valle F,Scaldalai E,Pessina AC

更新日期：1990-04-01 00:00:00

abstract：:Cardiac output was measured in 11 patients undergoing routine cardiac catheterization using a carbon dioxide rebreathing technique and compared with cardiac output measured by direct Fick and thermodilution. The carbon dioxide rebreathing technique gave consistently lower values for cardiac output than the other two m...

journal_title：European heart journal

authors： Nugent AM,McParland J,McEneaney DJ,Steele I,Campbell NP,Stanford CF,Nicholls DP

更新日期：1994-03-01 00:00:00

abstract：:Despite therapeutic improvements, cardiogenic shock (CS) remains the most common cause of death in patients with acute myocardial infarction (AMI). In addition to percutaneous coronary intervention, inotropes, fluids, adjunctive medication, intra-aortic balloon counterpulsation, and also assist devices are widely used...

journal_title：European heart journal

authors： Thiele H,Allam B,Chatellier G,Schuler G,Lafont A

更新日期：2010-08-01 00:00:00

abstract：AIM:Cross-sectional studies reported associations between short leucocyte telomere length (LTL) and measures of vascular and cardiac damage. However, the contribution of LTL dynamics to the age-related process of cardiovascular (CV) remodelling remains unknown. In this study, we explored whether the rate of LTL shorten...

journal_title：European heart journal

authors： Masi S,D'Aiuto F,Martin-Ruiz C,Kahn T,Wong A,Ghosh AK,Whincup P,Kuh D,Hughes A,von Zglinicki T,Hardy R,Deanfield JE,NSHD scientific and data collection teams.

更新日期：2014-12-07 00:00:00

abstract：:Echocardiographic parameters of left ventricular (LV) function were compared with the electrocardiographic findings in 40 patients with chronic severe aortic regurgitation. Total 12-lead QRS amplitude was linearly correlated with LV mass and its 'relative reduction' (less than 250 mm) indicated LV hypertrophy. Patient...

journal_title：European heart journal

authors： Scognamiglio R,Fasoli G,Bruni A,Dalla-Volta S

更新日期：1988-01-01 00:00:00

abstract：AIMS:Carotid-femoral pulse wave velocity (PWV), a direct measure of aortic stiffness, has become increasingly important for total cardiovascular (CV) risk estimation. Its application as a routine tool for clinical patient evaluation has been hampered by the absence of reference values. The aim of the present study is t...

journal_title：European heart journal

authors： Reference Values for Arterial Stiffness' Collaboration.

更新日期：2010-10-01 00:00:00

abstract：AIMS:Experimental and clinical studies indicate that tea exerts protection against cardiovascular diseases. However, a question of much debate is whether addition of milk modifies the biological activities of tea. We studied the vascular effects of tea, with or without milk, in humans and elucidated the impact of indiv...

journal_title：European heart journal

authors： Lorenz M,Jochmann N,von Krosigk A,Martus P,Baumann G,Stangl K,Stangl V

更新日期：2007-01-01 00:00:00

abstract：:The endothelium may play a role as a target and mediator of hypertension. Due to its anatomical position, it is very exposed to mechanical forces; as a source of vasoactive material it may participate in increasing peripheral vascular resistance and in promoting local ischaemia in the heart and brain. Morphological an...

journal_title：European heart journal

authors： Lüscher TF

更新日期：1992-09-01 00:00:00

abstract：:Plasma neuropeptide Y-like immunoreactivity (NPY-LI) is elevated in patients with acute myocardial ischaemia and congestive heart failure (CHF) owing to increased activity of the sympathetic nervous system. The prognostic value of plasma NPY-LI with regard to mortality was studied in 324 random patients admitted to a ...

journal_title：European heart journal

authors： Ullman B,Hulting J,Lundberg JM

更新日期：1994-04-01 00:00:00

abstract：:Clinical studies suggest that neutrophil activation during acute myocardial infarction (MI) aggravates tissue injury. Activated neutrophils are an important source of oxygen free radicals (OFR), the injurious effects of which are counteracted by endogenous antioxidants. We have previously shown in healthy subjects tha...

journal_title：European heart journal

authors： Herbaczyńska-Cedro K,K+osiewicz-Wasek B,Cedro K,Wasek W,Panczenko-Kresowska B,Wartanowicz M

更新日期：1995-08-01 00:00:00

abstract：:Right ventricular dysplasia (RVD) is a cardiac anomaly characterized by replacement of right ventricular myocardium by adipose and fibrous tissue that was first described at autopsy, and is now being recognized pre-mortem. Sudden death and ventricular arrhythmias are the most common clinical manifestation of the condi...

journal_title：European heart journal

authors： Strain J

更新日期：1989-09-01 00:00:00

abstract：:Previous evidence indicates that cells generate molecules that alter transcription in response to stress. Accordingly, we conducted preliminary experiments to characterize these molecules. Extracts were prepared from normal and experimental canine hearts in which a 100 mmHg gradient was created across the ascending ao...

journal_title：European heart journal

authors： Hammond GL,Lai YK,Markert CL

更新日期：1984-12-01 00:00:00

abstract：:Twelve patients with the long QT syndrome were studied to determine the usefulness of 123I-metaiodobenzylguanidine (MIBG) single-photon emission tomography (SPECT) at 2 h and 6 h after injection; the results were compared to 10 healthy volunteers (controls). Uptake of MIBG in the left ventricle at 2 h after injection ...

journal_title：European heart journal

authors： Müller KD,Jakob H,Neuzner J,Grebe SF,Schlepper M,Pitschner HF

更新日期：1993-03-01 00:00:00

abstract：:The scientific assessment of diagnostic tests should not be based upon a small series of results published by the best academic institutions, but ought to require large scale, multicentre validation founded on grass roots institutions with real doctors, real patients and real problems. To this purpose, an internationa...

journal_title：European heart journal

authors： Picano E,Sicari R,Landi P,Raciti M,Pingitore A,Vassalle C,Mathias W Jr,Lowenstein J,Petix N,Gigli G

更新日期：1995-10-01 00:00:00

abstract：:The concentration of cholesterol in peripheral lymph is roughly one tenth of that in the blood plasma of the same subject. In lymph, there is virtually no very low density lipoprotein (VLDL), probably due to low permeability of the vascular endothelium for particles of this size. More than 95% of apo B-containing lipo...

journal_title：European heart journal

authors： Reichl D

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Electrocardiographic abnormalities and premature ventricular contractions are common in athletes and are generally benign. However, the specific outcome of high-level endurance athletes with frequent and complex ventricular arrhythmias is unclear. Also, information on the predictive accuracy of different inv...

journal_title：European heart journal

authors： Heidbüchel H,Hoogsteen J,Fagard R,Vanhees L,Ector H,Willems R,Van Lierde J

更新日期：2003-08-01 00:00:00

abstract：:AIMS More intense platelet-directed therapy for acute coronary syndrome (ACS) may increase bleeding risk. The aim of the current analysis was to determine the rate, clinical impact, and predictors of major and fatal bleeding complications in the PLATO study. METHODS AND RESULTS PLATO was a randomized, double-blind, ac...

journal_title：European heart journal

authors： Becker RC,Bassand JP,Budaj A,Wojdyla DM,James SK,Cornel JH,French J,Held C,Horrow J,Husted S,Lopez-Sendon J,Lassila R,Mahaffey KW,Storey RF,Harrington RA,Wallentin L

更新日期：2011-12-01 00:00:00

abstract：:24 hour ambulatory electrocardiography was performed in a representative group of people born in 1897. Out of 73 people included in the study, 22 were without known heart disease, 15 had definite ischaemic heart disease (IHD) and 36 symptoms of possible cardiac origin. An R-R interval in excess of 2000 ms was seen in ...

journal_title：European heart journal

authors： Ingerslev J,Bjerregaard P

更新日期：1986-07-01 00:00:00

abstract：AIM:We tested the hypothesis that dapagliflozin may regress left ventricular hypertrophy (LVH) in people with type 2 diabetes (T2D). METHODS AND RESULTS:We randomly assigned 66 people (mean age 67 ± 7 years, 38 males) with T2D, LVH, and controlled blood pressure (BP) to receive dapagliflozin 10 mg once daily or placeb...

journal_title：European heart journal

authors： Brown AJM,Gandy S,McCrimmon R,Houston JG,Struthers AD,Lang CC

更新日期：2020-09-21 00:00:00

abstract：AIMS:There is growing need for the identification of novel non-invasive methodologies for the identification of individuals at risk for adverse cardiovascular (CV) events. We examined whether endothelial dysfunction, as detected by non-invasive peripheral arterial tonometry (EndoPAT), can predict late CV events. METHO...

journal_title：European heart journal

authors： Rubinshtein R,Kuvin JT,Soffler M,Lennon RJ,Lavi S,Nelson RE,Pumper GM,Lerman LO,Lerman A

更新日期：2010-05-01 00:00:00

abstract：:A patient with a three-year history of recurrent pulmonary embolism is presented. Thromboembolic pulmonary hypertension was proven in the final stage of disease in the presence of repeated episodes of systemic embolic events. Paradoxical embolism was assumed to be present on the basis of blood-gas analysis and contras...

journal_title：European heart journal

authors： Lang I,Steurer G,Weissel M,Burghuber OC

更新日期：1988-06-01 00:00:00

abstract：:Science has made enormous achievements for our understanding of the world and for everyday life: we now know that we live on a spherical planet of the solar system, we understand the origin of the species, we can take a train, survive myocardial infarction, and fly to the moon. This has been made possible thanks to a ...

journal_title：European heart journal

authors： Lüscher TF

更新日期：2013-04-01 00:00:00

abstract：:Myocardial protection and the control of ischemic injury has been highly successful clinically in the field of cardiac surgery where hearts are made globally ischemic. By contrast, protection of the regionally ischemic myocardium, as found during evolving myocardial infarction, has been less successful and, despite nu...

journal_title：European heart journal

authors： Hearse DJ

更新日期：1983-05-01 00:00:00