Assessment of endothelial function by non-invasive peripheral arterial tonometry predicts late cardiovascular adverse events.

abstract：AIMS:Hypertrophic cardiomyopathy (HCM) is a disease with marked regional differences in wall thickness. However, the relation between myocardial function and wall thickness has not been well studied. Ultrasonic strain rate (SR) imaging makes it possible to study the regional myocardial deformation. We investigated whet...

journal_title：European heart journal

authors： Ganame J,Mertens L,Eidem BW,Claus P,D'hooge J,Havemann LM,McMahon CJ,Elayda MA,Vaughn WK,Towbin JA,Ayres NA,Pignatelli RH

更新日期：2007-12-01 00:00:00

abstract：:Hypertension induced in rats by suprarenal banding has a blood pressure elevating effect that is accompanied by the occurrence of cardiac hypertrophy and fibrosis. This phenomenon is already present at 2 weeks after banding and persists up to 1.5 years. The increase in cardiac weight is mostly due to the development o...

journal_title：European heart journal

authors： Nagasawa K,Zimmermann R,Münkel B,Linz W,Schölkens B,Schaper J

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Endocardial mapping of atrial fibrillation in humans is limited by its low resolution and by complexities in the arrhythmia and atrial anatomy. METHODS AND RESULTS:A catheter mounted non-contact multielectrode was deployed in the right atrium of 11 patients with atrial fibrillation and used to reconstruct 3...

journal_title：European heart journal

authors： Schilling RJ,Kadish AH,Peters NS,Goldberger J,Davies DW

更新日期：2000-04-01 00:00:00

abstract：:It is not yet clear whether 99mTc-methoxyisobutyl-isonitrile (MIBI)-uptake is a reliable indicator of myocardial viability, and a threshold value, differentiating viable from scarred myocardium, in comparison to a morphological and functional standard of reference has not been defined. MIBI-uptake was quantified in 80...

journal_title：European heart journal

authors： Baer FM,Smolarz K,Theissen P,Voth E,Schicha H,Sechtem U

更新日期：1994-01-01 00:00:00

abstract：:Nucleic acid-based therapeutics are currently developed at large scale for prevention and management of cardiovascular diseases (CVDs), since: (i) genetic studies have highlighted novel therapeutic targets suggested to be causal for CVD; (ii) there is a substantial recent progress in delivery, efficacy, and safety of ...

journal_title：European heart journal

authors： Landmesser U,Poller W,Tsimikas S,Most P,Paneni F,Lüscher TF

更新日期：2020-10-21 00:00:00

abstract：AIMS:Here, we aimed to determine the therapeutic effect of longevity-associated variant (LAV)-BPIFB4 gene therapy on atherosclerosis. METHODS AND RESULTS:ApoE knockout mice (ApoE-/-) fed a high-fat diet were randomly allocated to receive LAV-BPIFB4, wild-type (WT)-BPIFB4, or empty vector via adeno-associated viral vec...

journal_title：European heart journal

authors： Puca AA,Carrizzo A,Spinelli C,Damato A,Ambrosio M,Villa F,Ferrario A,Maciag A,Fornai F,Lenzi P,Valenti V,di Nonno F,Accarino G,Madonna M,Forte M,Calì G,Baragetti A,Norata GD,Catapano AL,Cattaneo M,Izzo R,Trimarc

更新日期：2020-07-07 00:00:00

abstract：:The Belgian Heart Disease Prevention Project was a controlled, randomized multifactorial intervention trial in middle-aged men which lasted 6 years. Significant net differences between intervention and control groups were observed in change in risk profile, in total mortality and in CHD incidence. The net difference i...

journal_title：European heart journal

authors： De Backer G,Kornitzer M,Dramaix M,Kittel F,Thilly C,Graffar M,Vuylsteek K

更新日期：1988-03-01 00:00:00

abstract：AIMS:Intense exercise places disproportionate strain on the right ventricle (RV) which may promote pro-arrhythmic remodelling in some athletes. RV exercise imaging may enable early identification of athletes at risk of arrhythmias. METHODS AND RESULTS:Exercise imaging was performed in 17 athletes with RV ventricular a...

journal_title：European heart journal

authors： La Gerche A,Claessen G,Dymarkowski S,Voigt JU,De Buck F,Vanhees L,Droogne W,Van Cleemput J,Claus P,Heidbuchel H

更新日期：2015-08-07 00:00:00

abstract：:Strong experimental evidence links ventricular fibrillation to an increased temporal dispersion of the recovery of excitability. The effect of an overall prolongation of repolarization and an increased basic dispersion of repolarization on premature dispersion was studied on ventricular surface in 10 dogs. Our observa...

journal_title：European heart journal

authors： Amlie JP,Kuo CS,Munakata K,Reddy PS,Surawicz B

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Emerging evidence suggests that a mildly elevated body mass index (BMI), is related to improved survival and fewer cardiovascular events in patients with coronary artery disease (CAD). We hypothesize that these results are related to the poor diagnostic performance of BMI to detect adiposity, especially in t...

journal_title：European heart journal

authors： Romero-Corral A,Somers VK,Sierra-Johnson J,Jensen MD,Thomas RJ,Squires RW,Allison TG,Korinek J,Lopez-Jimenez F

更新日期：2007-09-01 00:00:00

abstract：:Twenty-nine men with chronic stable angina pectoris were investigated using stress electrocardiography (ECG) and stress transthoracic echocardiography by means of transoesophageal stimulation of the left atrium. At rest and after each stimulated frequency, ECG and 2-dimensional echocardiography combined with Doppler w...

journal_title：European heart journal

authors： Meluzín J,Novák M,Julínek J,Rihácek I,Urbánek D,Koukalová H,Toman J

更新日期：1993-10-01 00:00:00

abstract：:This study analyses the immediate outcome and the risk of recurrent restenosis in patients who, at the time of repeat coronary angioplasty for a first restenosis, had unstable (n = 50), 19%) or stable (n = 218, 81%) angina. Successful angioplasty was accomplished in 250 (93%) patients, 222 (89%) of whom had follow-up ...

journal_title：European heart journal

authors： Bauters C,Lablanche JM,McFadden EP,Leroy F,Bertrand ME

更新日期：1993-02-01 00:00:00

abstract：:An elevation of the cardiopulmonary baroreflex control of the forearm vascular resistances due to an impairment of the arterial baroreflex has been postulated in borderline hypertension. The purpose of the study is to verify this hypothesis. The arterial baroreflex sensitivity, measured by the phenylephrine method is ...

journal_title：European heart journal

authors： Bovy P,Juchmes J,Fossion A

更新日期：1983-11-01 00:00:00

abstract：:Subclinical thyroid dysfunction comprises subclinical hypothyroidism (SHypo), defined as elevated thyroid-stimulating hormone (TSH) by normal free thyroxine (FT4), and subclinical hyperthyroidism (SHyper) with decreased or undetectable TSH and normal FT4. Up to 10% of the elderly have SHypo, which is usually asymptoma...

journal_title：European heart journal

authors： Floriani C,Gencer B,Collet TH,Rodondi N

更新日期：2018-02-14 00:00:00

abstract：AIMS:We used the hospital discharge records of Piedmont region (northern Italy) to evaluate whether a national law banning smoking in public resulted in a short-term reduction in hospital admissions for acute myocardial infarction (AMI). METHODS AND RESULTS:Rates of admission for AMI before the ban (October-December 2...

journal_title：European heart journal

authors： Barone-Adesi F,Vizzini L,Merletti F,Richiardi L

更新日期：2006-10-01 00:00:00

abstract：:In the initial phase of heart failure, cardiac output and pressure are maintained by increasing sympathetic drive and by cell hypertrophy. Elevated end-diastolic volume, a reduced ejection fraction and a higher filling pressure also occur. Only in more severe heart failure, when cardiac output cannot be maintained, do...

journal_title：European heart journal

authors： Burkart F

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Antiarrhythmic drugs are still used for the treatment of ventricular tachyarrhythmias, in combination with implantable cardioverter-defibrillators or without them. AIM OF THE STUDY:In a double-blind randomized crossover design, the short- and long-term efficacy and safety of oral dofetilide or oral sotalol ...

journal_title：European heart journal

authors： Boriani G,Lubinski A,Capucci A,Niederle R,Kornacewicz-Jack Z,Wnuk-Wojnar AM,Borggrefe M,Brachmann J,Biffi M,Butrous GS,Ventricular Arrhythmias Dofetilide Investigators.

更新日期：2001-12-01 00:00:00

abstract：AIMS:In acute coronary syndromes (ACS), the optimal revascularization strategy for unprotected left main coronary disease (ULMCD) has been little studied. The objectives of the present study were to describe the practice of ULMCD revascularization in ACS patients and its evolution over an 8-year period, analyse the pro...

journal_title：European heart journal

authors： Montalescot G,Brieger D,Eagle KA,Anderson FA Jr,FitzGerald G,Lee MS,Steg PG,Avezum A,Goodman SG,Gore JM,GRACE Investigators.

更新日期：2009-10-01 00:00:00

abstract：AIMS:Cardiomyopathies are a heterogeneous group of disorders associated with premature death due to ventricular arrhythmia or heart failure. The purpose of this study was to examine the characteristics of patients enrolled in the pilot phase of the EURObservational Research Programme (EORP) cardiomyopathy registry. ME...

journal_title：European heart journal

authors： Elliott P,Charron P,Blanes JR,Tavazzi L,Tendera M,Konté M,Laroche C,Maggioni AP,EORP Cardiomyopathy Registry Pilot Investigators.

更新日期：2016-01-07 00:00:00

abstract：BACKGROUND:Sixteen cases of sudden unexpected cardiac death, 15 males and one female, are known to have occurred among young Swedish orienteers from 1979 to 1992, of which seven cases occurred between 1989 and 1992. This is considered to be indicative of an increased death rate. RESULTS:Histopathological evaluation sh...

journal_title：European heart journal

authors： Wesslén L,Påhlson C,Lindquist O,Hjelm E,Gnarpe J,Larsson E,Baandrup U,Eriksson L,Fohlman J,Engstrand L,Linglöf T,Nyström-Rosander C,Gnarpe H,Magnius L,Rolf C,Friman G

更新日期：1996-06-01 00:00:00

abstract：AIMS:The association of body weight and weight change with mortality and cardiovascular (CV) outcome in patients with diabetes mellitus (DM) is not clearly established. We assessed the relationship between weight, weight change, and outcomes in patients with established CV risk factors and type 2 DM or pre-diabetes. M...

journal_title：European heart journal

authors： Doehner W,Gerstein HC,Ried J,Jung H,Asbrand C,Hess S,Anker SD

更新日期：2020-07-21 00:00:00

abstract：AIMS:Nuclear receptors and their cofactors regulate key pathophysiological processes in atherosclerosis development. The transcriptional activity of these nuclear receptors is controlled by the nuclear receptor corepressors (NCOR), scaffolding proteins that form the basis of large corepressor complexes. Studies with pr...

journal_title：European heart journal

authors： Oppi S,Nusser-Stein S,Blyszczuk P,Wang X,Jomard A,Marzolla V,Yang K,Velagapudi S,Ward LJ,Yuan XM,Geiger MA,Guillaumon AT,Othman A,Hornemann T,Rancic Z,Ryu D,Oosterveer MH,Osto E,Lüscher TF,Stein S

更新日期：2020-03-01 00:00:00

abstract：AIMS:Transplant-associated coronary artery disease (TxCAD) is a major cause of post-transplant graft failure. The aim of this study was to investigate a possible role of mannose-binding lectin (MBL) deficiency and complement activation in TxCAD. METHODS AND RESULTS:In a prospective study of heart transplant recipients...

journal_title：European heart journal

authors： Fiane AE,Ueland T,Simonsen S,Scott H,Endresen K,Gullestad L,Geiran OR,Haraldsen G,Heggelund L,Andreassen AK,Wergeland R,Frøland S,Aukrust P,Mollnes TE

更新日期：2005-08-01 00:00:00

abstract：AIMS:Recent randomized trials suggest that intensive glycaemic control fails to reduce heart failure-related events in patients with diabetes. The molecular cues underlying persistent myocardial damage despite normoglycaemia restoration remain elusive. MicroRNAs (miRNAs), a class of small non-coding RNAs, orchestrate t...

journal_title：European heart journal

authors： Costantino S,Paneni F,Lüscher TF,Cosentino F

更新日期：2016-02-07 00:00:00

abstract：BACKGROUND:Recently, a new exercise test criterion diagnosing coronary artery disease was proposed, based on a composite of changes in Q-, R- and S-waves: the QRS score. We compared this new criterion with conventional ST-segment depression and other compositions of Q-, R- and S-wave changes in patients and normals and...

journal_title：European heart journal

authors： van Campen CM,Visser FC,Visser CA

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVES:The primary objectives of this study were to assess the feasibility of temperature-controlled radiofrequency catheter ablation of left and right sided manifest accessory pathways in patients with Wolff-Parkinson-White syndrome and to gain more insights into biophysical aspects of temperature-controlled cathe...

journal_title：European heart journal

authors： Willems S,Chen X,Kottkamp H,Hindricks G,Haverkamp W,Rotman B,Shenasa M,Breithardt G,Borggrefe M

更新日期：1996-03-01 00:00:00

abstract：:Eight young healthy male subjects, members of a Himalayan expedition, underwent 24 h Holter monitoring before departure, after 1 and 4 weeks at high altitude (5000 m) and after return to sea level. At high altitude, the circadian reciprocal changes in low and high frequency (LF, HF) were absent, with no significant re...

journal_title：European heart journal

authors： Ponchia A,Noventa D,Bertaglia M,Carretta R,Zaccaria M,Miraglia G,Pascotto P,Buja G

更新日期：1994-11-01 00:00:00

abstract：AIMS:This study investigated whether sedentary behaviour and different activity levels have an independent association with carotid intima-media thickness (IMT) and with the 3-year IMT progression in different carotid segments. METHODS AND RESULTS:The study population included 614 healthy men and women (mean age = 44 ...

journal_title：European heart journal

authors： Kozàkovà M,Palombo C,Morizzo C,Nolan JJ,Konrad T,Balkau B,RISC Investigators.

更新日期：2010-06-01 00:00:00

abstract：AIMS:Positron emission tomography (PET) myocardial perfusion imaging (MPI) can non-invasively measure myocardial blood flow reserve (MBFR). We aimed to examine whether MBFR identifies patients with a survival benefit after revascularization, helping to guide post-test management. METHODS AND RESULTS:We examined all-ca...

journal_title：European heart journal

authors： Patel KK,Spertus JA,Chan PS,Sperry BW,Al Badarin F,Kennedy KF,Thompson RC,Case JA,McGhie AI,Bateman TM

更新日期：2020-02-01 00:00:00

abstract：AIMS:This study investigated the functional outcome of wall-thinned, akinetic myocardium after revascularization and evaluated the accuracy of dobutamine echocardiography in predicting post-revascularization functional recovery with the assessment of end-diastolic wall thickness in chronic ischaemic patients. METHODS ...

journal_title：European heart journal

authors： Furukawa T,Haque T,Takahashi M,Kinoshita M

更新日期：1997-05-01 00:00:00