Abstract:
AIMS:Intense exercise places disproportionate strain on the right ventricle (RV) which may promote pro-arrhythmic remodelling in some athletes. RV exercise imaging may enable early identification of athletes at risk of arrhythmias. METHODS AND RESULTS:Exercise imaging was performed in 17 athletes with RV ventricular arrhythmias (EA-VAs), of which eight (47%) had an implantable cardiac defibrillator (ICD), 10 healthy endurance athletes (EAs), and seven non-athletes (NAs). Echocardiographic measures included the RV end-systolic pressure-area ratio (ESPAR), RV fractional area change (RVFAC), and systolic tricuspid annular velocity (RV S'). Cardiac magnetic resonance (CMR) measures combined with invasive measurements of pulmonary and systemic artery pressures provided left-ventricular (LV) and RV end-systolic pressure-volume ratios (SP/ESV), biventricular volumes, and ejection fraction (EF) at rest and during intense exercise. Resting measures of cardiac function were similar in all groups, as was LV function during exercise. In contrast, exercise-induced increases in RVFAC, RV S', and RVESPAR were attenuated in EA-VAs during exercise when compared with EAs and NAs (P < 0.0001 for interaction group × workload). During exercise-CMR, decreases in RVESV and augmentation of both RVEF and RV SP/ESV were significantly less in EA-VAs relative to EAs and NAs (P < 0.01 for the respective interactions). Receiver-operator characteristic curves demonstrated that RV exercise measures could accurately differentiate EA-VAs from subjects without arrhythmias [AUC for ΔRVESPAR = 0.96 (0.89-1.00), P < 0.0001]. CONCLUSION:Among athletes with normal cardiac function at rest, exercise testing reveals RV contractile dysfunction among athletes with RV arrhythmias. RV stress testing shows promise as a non-invasive means of risk-stratifying athletes.
journal_name
Eur Heart Jjournal_title
European heart journalauthors
La Gerche A,Claessen G,Dymarkowski S,Voigt JU,De Buck F,Vanhees L,Droogne W,Van Cleemput J,Claus P,Heidbuchel Hdoi
10.1093/eurheartj/ehv202subject
Has Abstractpub_date
2015-08-07 00:00:00pages
1998-2010issue
30eissn
0195-668Xissn
1522-9645pii
ehv202journal_volume
36pub_type
杂志文章abstract::Clonidine administration by i.v. infusion in 12 patients with hypertension emergencies (diastolic blood pressure over 130 mmHg) resulted in the normalization of blood pressure (BP) in all patients. Lowering of BP was associated with a reduction in total and lower limb vascular resistance. Heart rate showed a slight an...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a061605
更新日期:1984-12-01 00:00:00
abstract::In a prospective study, an elderly group of patients (n = 63, 47 male, 16 female, age 40-65 years) was examined before and after open-heart surgery under cardiopulmonary bypass: postoperatively, 19 patients (30%) showed no clinical neuropsychiatric symptoms, whereas in 35 patients (56%) mild or transient neurological ...
journal_title:European heart journal
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doi:10.1093/eurheartj/14.7.885
更新日期:1993-07-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2013-07-01 00:00:00
abstract::The present review discusses the prognostic significance of post-infarction angina pectoris, and the significance of post-infarction intervention with verapamil on the prevalence of post-infarction ischaemia and prognosis. Angina pectoris during the first month after acute myocardial infarction (AMI) was found to be a...
journal_title:European heart journal
pub_type: 杂志文章,评审
doi:10.1093/eurheartj/16.suppl_h.13
更新日期:1995-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a059838
更新日期:1991-10-01 00:00:00
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journal_title:European heart journal
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doi:10.1093/eurheartj/ehi022
更新日期:2005-01-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章,评审
doi:10.1093/eurheartj/ehl381
更新日期:2006-12-01 00:00:00
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doi:10.1093/eurheartj/ehz667
更新日期:2020-03-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章,评审
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更新日期:1993-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a061937
更新日期:1985-09-01 00:00:00
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journal_title:European heart journal
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1994-12-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章,评审
doi:10.1093/eurheartj/16.suppl_k.4
更新日期:1995-11-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章
doi:
更新日期:1991-09-01 00:00:00
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journal_title:European heart journal
pub_type: 共识发展会议,杂志文章
doi:10.1093/eurheartj/ehy077
更新日期:2018-06-07 00:00:00
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更新日期:2013-09-01 00:00:00
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journal_title:European heart journal
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更新日期:1984-11-01 00:00:00
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更新日期:2016-03-07 00:00:00
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doi:10.1093/oxfordjournals.eurheartj.a062543
更新日期:1988-05-01 00:00:00
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journal_title:European heart journal
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更新日期:1987-10-01 00:00:00
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journal_title:European heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2006-01-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2017-11-07 00:00:00
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更新日期:2015-09-07 00:00:00
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pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a014946
更新日期:1996-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:2006-04-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2005-06-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1093/eurheartj/10.suppl_e.2
更新日期:1989-09-01 00:00:00