Experimental electrophysiology and arrhythmogenicity. Anisotropy and ventricular tachycardia.

abstract：AIMS:To test the hypothesis that diabetic status may be used as a prognostic indicator in heart failure (HF) patients. METHODS AND RESULTS:We studied 1246 consecutive patients with left ventricular dysfunction. All patients had a cardiopulmonary exercise test and an echocardiogram. Cardiac catheterisation was systemat...

journal_title：European heart journal

authors： De Groote P,Lamblin N,Mouquet F,Plichon D,McFadden E,Van Belle E,Bauters C

更新日期：2004-04-01 00:00:00

abstract：:We have conducted a randomized, double-blind, placebo-controlled multicentre trial of oral isosorbide 5-mononitrate (ISMN) in 360 patients with suspected acute myocardial infarction. Patients were stratified prior to analysis according to the presence or absence of left ventricular failure on admission. ISMN caused a ...

journal_title：European heart journal

authors： Fitzgerald LJ,Bennett ED

更新日期：1990-02-01 00:00:00

abstract：AIMS:Morphological characteristics of non-significant coronary plaques (NSCPs) that develop rapid progression have not been fully elucidated. The aim of this study was to clarify the morphological characteristics of NSCPs in patients with coronary artery disease (CAD) using intravascular optical coherence tomography (O...

journal_title：European heart journal

authors： Uemura S,Ishigami K,Soeda T,Okayama S,Sung JH,Nakagawa H,Somekawa S,Takeda Y,Kawata H,Horii M,Saito Y

更新日期：2012-01-01 00:00:00

abstract：:Falipamil hydrochloride (AQA 39) is a new antiarrhythmic agent structurally related to verapamil. We evaluated the electrophysiologic properties of intravenous falipamil (1.5 mg kg-1 within 20 minutes) in 12 patients. The spontaneous cycle length was significantly (P less than 0.001) prolonged (+79 +/- 59 ms). Atriove...

journal_title：European heart journal

authors： Lévy S,Mètge M,Hilaire J,Cointe R,Bru P,Eychenne JL,Gérard R

更新日期：1987-11-01 00:00:00

abstract：AIMS:Support with left ventricular assist devices (LVAD) improves cardiac performance in patients with end-stage heart failure. In some cases this strategy, combined with pharmacological treatment, has led to a clinical improvement which remained after LVAD explant. This study defines changes in Ca handling at the cell...

journal_title：European heart journal

authors： Terracciano CM,Harding SE,Adamson D,Koban M,Tansley P,Birks EJ,Barton PJ,Yacoub MH

更新日期：2003-07-01 00:00:00

abstract：:Twelve patients with the long QT syndrome were studied to determine the usefulness of 123I-metaiodobenzylguanidine (MIBG) single-photon emission tomography (SPECT) at 2 h and 6 h after injection; the results were compared to 10 healthy volunteers (controls). Uptake of MIBG in the left ventricle at 2 h after injection ...

journal_title：European heart journal

authors： Müller KD,Jakob H,Neuzner J,Grebe SF,Schlepper M,Pitschner HF

更新日期：1993-03-01 00:00:00

abstract：:AIMS More intense platelet-directed therapy for acute coronary syndrome (ACS) may increase bleeding risk. The aim of the current analysis was to determine the rate, clinical impact, and predictors of major and fatal bleeding complications in the PLATO study. METHODS AND RESULTS PLATO was a randomized, double-blind, ac...

journal_title：European heart journal

authors： Becker RC,Bassand JP,Budaj A,Wojdyla DM,James SK,Cornel JH,French J,Held C,Horrow J,Husted S,Lopez-Sendon J,Lassila R,Mahaffey KW,Storey RF,Harrington RA,Wallentin L

更新日期：2011-12-01 00:00:00

abstract：:Chronically ischaemic myocardium from patients with coronary heart disease was investigated by light and electron microscopy using tissue biopsies taken during cardiac surgery. Light microscopy showed a significantly increased amount of fibrotic material, cell size was variable. By electron microscopy, the most obviou...

journal_title：European heart journal

authors： Schaper J

更新日期：1988-01-01 00:00:00

abstract：AIMS:To identify changes in multidirectional strain and strain rate (SR) in patients with aortic stenosis (AS). METHODS AND RESULTS:A total of 420 patients (age 66.1 ± 14.5 years, 60.7% men) with aortic sclerosis, mild, moderate, and severe AS with preserved left ventricular (LV) ejection fraction [(EF), ≥50%] were in...

journal_title：European heart journal

authors： Ng AC,Delgado V,Bertini M,Antoni ML,van Bommel RJ,van Rijnsoever EP,van der Kley F,Ewe SH,Witkowski T,Auger D,Nucifora G,Schuijf JD,Poldermans D,Leung DY,Schalij MJ,Bax JJ

更新日期：2011-06-01 00:00:00

abstract：AIM:Decreasing cholesterol levels in Western populations is the main reason for decreasing mortality due to coronary heart disease. Our aim was to analyze trends in cholesterol levels in the population during a period of 20 years in relation to previous cardiovascular disease (CVD), other cardiovascular risk factors, a...

journal_title：European heart journal

authors： Eriksson M,Forslund AS,Jansson JH,Söderberg S,Wennberg M,Eliasson M

更新日期：2016-07-01 00:00:00

abstract：AIMS:This study investigated the relationship between right ventricular (RV) structure and function and survival in idiopathic pulmonary arterial hypertension (IPAH). METHODS AND RESULTS:In 64 patients, cardiac magnetic resonance, right heart catheterization, and the six-minute walk test (6MWT) were performed at basel...

journal_title：European heart journal

authors： van Wolferen SA,Marcus JT,Boonstra A,Marques KM,Bronzwaer JG,Spreeuwenberg MD,Postmus PE,Vonk-Noordegraaf A

更新日期：2007-05-01 00:00:00

abstract：AIMS:To present the design of ACTION (A Coronary disease Trial Investigating Outcome with Nifedipine GITS), an ongoing multicentre clinical outcome trial with nifedipine GITS (Gastro-Intestinal Therapeutic System) in patients with stable angina pectoris. METHODS:At least 6000 patients with optimally treated stable ang...

journal_title：European heart journal

authors： Lubsen J,Poole-Wilson PA,Pocock SJ,van Dalen FJ,Baumann J,Kirwan BA,Parker AB

更新日期：1998-08-01 00:00:00

abstract：:In the interpretation of the effect of a drug or intervention in a single patient, it is desirable to know the spontaneous fluctuations of the variable under study. A few studies have determined pulmonary haemodynamic variability in acute and short-term intervals. It seems reasonable to adopt a confidence limit of 6 m...

journal_title：European heart journal

authors： Schrijen F,Jezková J

更新日期：1988-09-01 00:00:00

abstract：AIMS:There is little evidence to inform routine practice in the use of coronary angiography and revascularization procedures after acute myocardial infarction. Large differences in the uptake of these procedures have been reported but representative data are scarce. Outcome studies have produced opposing conclusions co...

journal_title：European heart journal

authors： Woods KL,Ketley D,Agusti A,Hagn C,Kala R,Karatzas NB,Leizorowicz A,Reikvam A,Schilling J,Seabra-Gomes R,Vasiliauskas D,Wilhelmsen L

更新日期：1998-09-01 00:00:00

abstract：AIMS:Anticancer therapies have extended the lives of millions of patients with malignancies, but for some this benefit is tempered by adverse cardiovascular (CV) effects. Cardiotoxicity may occur early or late after treatment initiation or termination. The extent of this cardiotoxicity is variable, depending on the typ...

journal_title：European heart journal

authors： Lancellotti P,Suter TM,López-Fernández T,Galderisi M,Lyon AR,Van der Meer P,Cohen Solal A,Zamorano JL,Jerusalem G,Moonen M,Aboyans V,Bax JJ,Asteggiano R

更新日期：2019-06-07 00:00:00

abstract：AIMS:This study investigated the effects of irbesartan vs. enalapril, with early vs. late treatment, on markers of inflammation and ischaemic heart disease in patients with non-ST-segment elevation acute coronary syndrome (NSTEACS). METHODS AND RESULTS:Patients hospitalized with ischaemic symptoms and evidence of NSTE...

journal_title：European heart journal

authors： Montalescot G,Drexler H,Gallo R,Pearson T,Thoenes M,Bhatt DL

更新日期：2009-11-01 00:00:00

abstract：AIMS:Circulating progenitor cells (PC) may contribute to myocardial recovery following infarction. Growth factors including VEGF are produced during ischaemia and stimulate PC release and activation. In this study, we focused on the functional chemotactic response of PC to VEGF in subjects early after myocardial ischae...

journal_title：European heart journal

authors： Vöö S,Eggermann J,Dunaeva M,Ramakers-van Oosterhoud C,Waltenberger J

更新日期：2008-01-01 00:00:00

abstract：:Clinicians have long suspected that hypertrophied hearts have an inadequate coronary circulation. This clinical suspicion resulted from the observation that a large proportion of patients with left ventricular hypertrophy who have normal coronary arteriograms complain of angina and have ischaemia-like ST segment depre...

journal_title：European heart journal

authors： Kaski JC

更新日期：1993-11-01 00:00:00

abstract：AIMS:To investigate the association between neutrophil count, outcomes, and benefit of clopidogrel therapy in ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS:Baseline neutrophil count was measured in 2865 patients in CLARITY-TIMI 28, a randomized trial of clopidogrel vs. placebo in STEMI patients under...

journal_title：European heart journal

authors： O'Donoghue M,Morrow DA,Cannon CP,Guo W,Murphy SA,Gibson CM,Sabatine MS

更新日期：2008-04-01 00:00:00

abstract：:Brief hyperventilation is occasionally accompanied by repolarization abnormalities in subjects without apparent heart disease. However, the effect of prolonged hyperventilation on repolarization abnormalities is not clearly defined. We analysed the repolarization abnormalities induced by prolonged hyperventilation, co...

journal_title：European heart journal

authors： Alexopoulos D,Christodoulou J,Toulgaridis T,Sitafidis G,Manias O,Hahalis G,Vagenakis AG

更新日期：1996-09-01 00:00:00

abstract：AIMS:To evaluate efficacy and safety of intrapericardial treatment with the crystalloid corticosteroid triamcinolone in autoreactive pericardial effusion. METHODS AND RESULTS:Two hundred and sixty consecutive patients with pericarditis/myopericarditis underwent pericardiocentesis, pericardioscopy (Storz-AF1101B1), and...

journal_title：European heart journal

authors： Maisch B,Ristić AD,Pankuweit S

更新日期：2002-10-01 00:00:00

abstract：:Thrombolytic treatment efficacy is greater when the delay between onset of pain and treatment is short. One way to shorten this delay is to give treatment at home, but one cannot recommend this technique if it has not been demonstrated first, that pre-hospital thrombolysis is feasible and safe, and second, that it is ...

journal_title：European heart journal

authors： Castaigne AD,Hervé C,Duval-Moulin AM,Gaillard M,Dubois-Randé JL,Lellouche D

更新日期：1990-08-01 00:00:00

abstract：:In this double-blind placebo-controlled study with enalapril, 74 patients with acute myocardial infarction were followed at 0, 7, 30, 60 and 180 days after the event. Platelets and leukocytes were activated during the first 7 days. During the 6-month period fibrinogen, leukocytes, elastase, and B beta 30-43 remained e...

journal_title：European heart journal

authors： Sylvén C,Hagerman I,Karlberg KE,Chen J,Wallin R,Eneroth P,Bergström K,Saldeen T

更新日期：1995-12-01 00:00:00

abstract：AIMS:Coronary artery calcium (CAC) scoring has emerged as a tool for risk stratification and potentially for monitoring response to risk factor modification. Therefore, repeat measurements should provide robust results and low inter-scanner variability for allowing meaningful comparison. The purpose of this study was t...

journal_title：European heart journal

authors： Ghadri JR,Goetti R,Fiechter M,Pazhenkottil AP,Küest SM,Nkoulou RN,Windler C,Buechel RR,Herzog BA,Gaemperli O,Templin C,Kaufmann PA

更新日期：2011-08-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) can be a rapidly progressive disorder and is associated with high rate of mortality, despite medical intervention. With the availability of effective therapy, early disease detection is an important strategic objective to improve treatment outcomes. Resting echocardiography is cur...

journal_title：European heart journal

authors： Lau EM,Manes A,Celermajer DS,Galiè N

更新日期：2011-10-01 00:00:00

abstract：:Atrial fibrillation is a common arrhythmia and one which may cause pilot incapacitation. In many cases there may be no more than one episode and there will be no organic heart disease. Prediction of the risk of recurrence is not possible. Atrial fibrillation in both paroxysmal and persistent forms should be disqualify...

journal_title：European heart journal

authors： Bennett D

更新日期：1984-03-01 00:00:00

abstract：AIMS:The study set out to assess the relative contributions of donor heart rate, respiration and recipient atrial contraction on the mean of pulsed wave transmitral Doppler flow indices in orthotopic heart transplant recipients. This would provide information on the theoretical usefulness of pacemaker synchronization o...

journal_title：European heart journal

authors： Mannaerts H,Balk A,Roelandt J

更新日期：1997-10-01 00:00:00

abstract：AIM:This study reports on the results and safety of a simplified method of trans-septal catheterization for radiofrequency catheter ablation of cardiac arrhythmias. METHODS AND RESULTS:Over 5 years, 411 patients underwent trans-septal catheterization for radiofrequency catheter ablation: 388 patients had a left-sided ...

journal_title：European heart journal

authors： De Ponti R,Zardini M,Storti C,Longobardi M,Salerno-Uriarte JA

更新日期：1998-06-01 00:00:00

abstract：:Although the number of individuals reaching 80 who are considered to be healthy is increasing, the very elderly are likely to have long-term conditions, to report symptoms and/or be taking at least one regular medication. The impact of antihypertensive treatment has to be taken into account in this context. The treatm...

journal_title：European heart journal

authors： Peters R,Beckett N,McCormack T,Fagard R,Fletcher A,Bulpitt C

更新日期：2014-07-01 00:00:00

abstract：:To investigate the antianginal efficacy and tolerability of felodipine, a new dihydropyridine calcium antagonist, 20 patients with stable exertional angina, not completely controlled by beta-blocker monotherapy, entered a randomized, double-blind, placebo-controlled, crossover study. Patients on standard beta-blocker ...

journal_title：European heart journal

authors： Sangiorgio P,Di Pasquale G,Savonitto S,Urbinati S,Rubboli A,Cavallotti G,Pinelli G,Bracchetti D

更新日期：1990-11-01 00:00:00