Maternal MTHFR 677C>T is a risk factor for congenital heart defects: effect modification by periconceptional folate supplementation.

abstract：:During a 3-year period 2500 asymptomatic male aviators were screened routinely for coronary artery disease by maximal bicycle exercise testing. In 55 cases (2.1%) the exercise ECG was abnormal (40 subjects exhibited ST depression, 14 ventricular ectopic activity and in one subject both abnormalities were observed). Fu...

journal_title：European heart journal

authors： Pedersen F,Sandøe E,Laerkeborg A

更新日期：1991-07-01 00:00:00

abstract：:Strong experimental evidence links ventricular fibrillation to an increased temporal dispersion of the recovery of excitability. The effect of an overall prolongation of repolarization and an increased basic dispersion of repolarization on premature dispersion was studied on ventricular surface in 10 dogs. Our observa...

journal_title：European heart journal

authors： Amlie JP,Kuo CS,Munakata K,Reddy PS,Surawicz B

更新日期：1985-11-01 00:00:00

abstract：:The European Myocardial Infarction Project (E.M.I.P.) participants have evaluated out-of-hospital coronary care services in different cities within the E.E.C. and concluded that these facilities would support a study within these European centres on pre-hospital intervention in myocardial infarction. Based on a pilot ...

journal_title：European heart journal

authors：

更新日期：1988-02-01 00:00:00

abstract：:The transdermal nitroglycerin patches have been very successful nitrate formulations since their introduction in 1982. Nevertheless, considerable controversy regarding efficacy and tolerance has arisen. Nitroglycerin has multiple mechanisms of action in angina pectoris. Transdermal nitroglycerin in ointment formulatio...

journal_title：European heart journal

authors： Abrams J

更新日期：1989-05-01 00:00:00

abstract：AIMS:Supernatants of serum-free cultured mononuclear cells (MNC) contain a mix of immunomodulating factors (secretome), which have been shown to attenuate detrimental inflammatory responses following myocardial ischaemia. Inflammatory dilated cardiomyopathy (iDCM) is a common cause of heart failure in young patients. E...

journal_title：European heart journal

authors： Hoetzenecker K,Zimmermann M,Hoetzenecker W,Schweiger T,Kollmann D,Mildner M,Hegedus B,Mitterbauer A,Hacker S,Birner P,Gabriel C,Gyöngyösi M,Blyszczuk P,Eriksson U,Ankersmit HJ

更新日期：2015-03-14 00:00:00

abstract：:Acute myocardial infarction remains the principal cause of death in people aged over 40 years, despite the reductions in coronary heart disease (CHD) mortality that have been observed over the past 25 years in many European countries. Consequently, there is considerable potential to decrease further the risk of cardio...

journal_title：European heart journal

authors： Shepherd J

更新日期：1998-10-01 00:00:00

abstract：:The acute electrophysiologic effects of clinical doses of procainamide, lidocaine, metoprolol, digoxin and atropine upon the conduction of ventricular premature beats, were studied in 48 healthy volunteers. The conduction time of the first premature beat, induced 1 ms after the ventricular effective refractory period ...

journal_title：European heart journal

authors： Edvardsson N,Hirsch I,Olsson SB

更新日期：1985-01-01 00:00:00

abstract：:Adolescent CD-1 mice inoculated with coxsackievirus B3 (CVB3m) will develop acute myocarditis with focal lesions by 7 days post-inoculation (p.i.). Administration of murine sera containing anti-CVB3m-neutralizing antibodies into CVB3m-inoculated mice at 3 days p.i. will exacerbate myocarditis, suggesting the presence ...

journal_title：European heart journal

authors： Gauntt CJ,Arizpe HM,Higdon AL,Rozek MM,Crawley R,Cunningham MW

更新日期：1991-08-01 00:00:00

abstract：AIMS:To assess the prognostic significance of infarct core tissue characteristics using cardiac magnetic resonance (CMR) imaging in survivors of acute ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS:We performed an observational prospective single centre cohort study in 300 reperfused STEMI patients (m...

journal_title：European heart journal

authors： Carrick D,Haig C,Rauhalammi S,Ahmed N,Mordi I,McEntegart M,Petrie MC,Eteiba H,Hood S,Watkins S,Lindsay M,Mahrous A,Ford I,Tzemos N,Sattar N,Welsh P,Radjenovic A,Oldroyd KG,Berry C

更新日期：2016-04-01 00:00:00

abstract：UNLABELLED:Peripheral vessels provide a useful in vivo haemodynamic model allowing evaluation of local intravascular fluid dynamics. Velocity measurements using a 0.018 inch Doppler-tipped angioplasty guidewire, quantitative angiography and laboratory data were gathered from 45 patients with a total of 48 percutaneous ...

journal_title：European heart journal

authors： Wellnhofer E,Biamino G,Sauer HU,Trebeljahr A,Stalke J,Ragg C,Oswald H,Gotze S,Fleck E,Felix R

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:The calculation of valve resistance (R) rather than aortic valve area (AVA) has been proposed for the assessment of aortic stenosis (AS), based on the claim that it is less flow-dependent. Even more importantly, valve resistance has been reported to distinguish between truly severe and "pseudosevere" AS in p...

journal_title：European heart journal

authors： Mascherbauer J,Schima H,Rosenhek R,Czerny M,Maurer G,Baumgartner H

更新日期：2004-05-01 00:00:00

abstract：:Over two decades after the introduction of cardiac resynchronization therapy (CRT) into clinical practice, ∼30% of candidates continue to fail to respond to this highly effective treatment of drug-refractory heart failure (HF). Since the causes of this non-response (NR) are multifactorial, it will require multidiscipl...

journal_title：European heart journal

authors： Daubert C,Behar N,Martins RP,Mabo P,Leclercq C

更新日期：2017-05-14 00:00:00

abstract：:Human cytomegalovirus (CMV) can persist in many organs after primary infection. Not only is it suspected to cause morbidity during reactivation in patients under immunosuppression, but it may also induce long-term latency by chronic disease, e.g. in the myocardium. Endomyocardial biopsies of 27 patients with active my...

journal_title：European heart journal

authors： Schönian U,Crombach M,Maser S,Maisch B

更新日期：1995-12-01 00:00:00

abstract：AIM:A genetic variant (rs20417) of the PTGS2 gene, encoding for COX-2, has been associated with decreased COX-2 activity and a decreased risk of cardiovascular disease (CVD). However, this genetic association and the role of COX-2 in CVD remain controversial. METHODS AND RESULTS:The association of rs20417 with CVD was...

journal_title：European heart journal

authors： Ross S,Eikelboom J,Anand SS,Eriksson N,Gerstein HC,Mehta S,Connolly SJ,Rose L,Ridker PM,Wallentin L,Chasman DI,Yusuf S,Paré G

更新日期：2014-09-01 00:00:00

abstract：AIMS:Inflammatory markers are established risk factors for atrial fibrillation (AF), but the role of autoimmune diseases is unknown. The aim of the study was to examine the association between coeliac disease (CD) and AF in a large cohort of patients with biopsy-verified CD. METHODS AND RESULTS:We identified 28,637 pa...

journal_title：European heart journal

authors： Emilsson L,Smith JG,West J,Melander O,Ludvigsson JF

更新日期：2011-10-01 00:00:00

abstract：:During urgent cardiac catheterization total occlusion of a severe left main coronary artery stenosis occurred, leading to profound cardiogenic shock. The patient survived, after prompt left main coronary angioplasty was performed, followed by emergency coronary bypass surgery. ...

journal_title：European heart journal

authors： Groves PH,Ikram S,Hayward MW,Hall RJ

更新日期：1989-12-01 00:00:00

abstract：:An investigation was undertaken to assess the value of adding streptokinase therapy to standard penicillin treatment of artificially induced infective endocarditis due to Streptococcus sanguis. In pigs a low-grade infection could be induced which closely simulated streptococcal endocarditis in man, but for technical r...

journal_title：European heart journal

authors： Dewar HA,Jones MR,Barnes WS,Griffin SG

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Recent identification of mutations in the beta-myosin heavy chain gene (MYH7), a major responsible gene for HCM, has provided the opportunity to characterize genotype-phenotype correlation in HCM families. In this study we analysed the phenotypic expression of two beta-myosin heavy chain (beta MHC) mutations...

journal_title：European heart journal

authors： Marian AJ,Mares A Jr,Kelly DP,Yu QT,Abchee AB,Hill R,Roberts R

更新日期：1995-03-01 00:00:00

abstract：:Glycaemic control is an inadequate surrogate marker of cardiovascular event reduction in patients with type 2 diabetes. Clinical trials to date have been unsuccessful in identifying a therapeutic approach that addresses the underlying problem in diabetes (glycaemic control) and reduces cardiovascular risk. The potenti...

journal_title：European heart journal

authors： Zannad F,Stough WG,Pocock SJ,Sleight P,Cushman WC,Cleland JG,McMurray JJ,Lonn E,Geller NL,Wedel H,Abadie E,Alonso-Garcia A,Pitt B

更新日期：2012-05-01 00:00:00

abstract：:The primary success rate and incidence of major complications have been retrospectively assessed in a consecutive series of 224 patients undergoing percutaneous transluminal coronary angioplasty (PTCA) in one centre. The patients have been divided into three groups; those with angina and no previous myocardial infarct...

journal_title：European heart journal

authors： Perry RA,Seth A,Singh A,Shiu MF

更新日期：1988-01-01 00:00:00

abstract：:Falipamil hydrochloride (AQA 39) is a new antiarrhythmic agent structurally related to verapamil. We evaluated the electrophysiologic properties of intravenous falipamil (1.5 mg kg-1 within 20 minutes) in 12 patients. The spontaneous cycle length was significantly (P less than 0.001) prolonged (+79 +/- 59 ms). Atriove...

journal_title：European heart journal

authors： Lévy S,Mètge M,Hilaire J,Cointe R,Bru P,Eychenne JL,Gérard R

更新日期：1987-11-01 00:00:00

abstract：AIMS:There is little evidence to inform routine practice in the use of coronary angiography and revascularization procedures after acute myocardial infarction. Large differences in the uptake of these procedures have been reported but representative data are scarce. Outcome studies have produced opposing conclusions co...

journal_title：European heart journal

authors： Woods KL,Ketley D,Agusti A,Hagn C,Kala R,Karatzas NB,Leizorowicz A,Reikvam A,Schilling J,Seabra-Gomes R,Vasiliauskas D,Wilhelmsen L

更新日期：1998-09-01 00:00:00

abstract：AIMS:No-reflow after a primary percutaneous coronary intervention (PCI) is associated with a high incidence of left ventricular (LV) failure and a poor prognosis. Endothelin-1 (ET-1) is a potent endothelium-derived vasoconstrictor peptide and an important modulator of neutrophil function. Elevated systemic ET-1 levels ...

journal_title：European heart journal

authors： Niccoli G,Lanza GA,Shaw S,Romagnoli E,Gioia D,Burzotta F,Trani C,Mazzari MA,Mongiardo R,De Vita M,Rebuzzi AG,Lüscher TF,Crea F

更新日期：2006-08-01 00:00:00

abstract：:The effects of fentanyl at a dose of 100 micrograms.kg-1 on cardiac automaticity, refractoriness and conduction have been studied in a model of heterotopic heart transplantation which combines a denervated heart (donor) and a non-denervated heart (recipient) in each of 20 dogs employed. Once the surgical procedure had...

journal_title：European heart journal

authors： Alvarez L,Escudero C,Carmona JA,Silva L,Castillo-Olivares JL

更新日期：1992-09-01 00:00:00

abstract：AIMS:Several factors are known to increase risk for cerebrovascular disease and dementia, but there is limited evidence on associations between multiple vascular risk factors (VRFs) and detailed aspects of brain macrostructure and microstructure in large community-dwelling populations across middle and older age. METH...

journal_title：European heart journal

authors： Cox SR,Lyall DM,Ritchie SJ,Bastin ME,Harris MA,Buchanan CR,Fawns-Ritchie C,Barbu MC,de Nooij L,Reus LM,Alloza C,Shen X,Neilson E,Alderson HL,Hunter S,Liewald DC,Whalley HC,McIntosh AM,Lawrie SM,Pell JP,Tucker-Drob

更新日期：2019-07-21 00:00:00

abstract：AIMS:This study was designed to compare the degree of inhibition of platelet aggregation (IPA) of prasugrel with that of clopidogrel in stable aspirin-treated patients with coronary artery disease (CAD). METHODS AND RESULTS:Subjects (n=101) were randomly assigned to the following loading dose (LD) (day 1)/maintenance ...

journal_title：European heart journal

authors： Jernberg T,Payne CD,Winters KJ,Darstein C,Brandt JT,Jakubowski JA,Naganuma H,Siegbahn A,Wallentin L

更新日期：2006-05-01 00:00:00

abstract：Aims:Bioresorbable scaffolds (BRS) provide short-term coronary artery scaffolding and drug delivery. Although prior trials showed a higher rate of device failure compared with conventional drug-eluting stents (DES), only a single trial investigated patients undergoing percutaneous coronary intervention (PCI) for acute ...

journal_title：European heart journal

authors： Byrne RA,Alfonso F,Schneider S,Maeng M,Wiebe J,Kretov E,Bradaric C,Rai H,Cuesta J,Rivero F,Hoppmann P,Schlichtenmaier J,Christiansen EH,Cassese S,Joner M,Schunkert H,Laugwitz KL,Kastrati A

更新日期：2019-01-07 00:00:00

abstract：:Unstable angina is a high-risk phase of coronary heart disease defined by clinical symptoms. Electrocardiographic findings are heterogeneous and creatine kinase is only rarely elevated. However, troponin T and troponin I are found in about 30-40% of patients with angina at rest disclosing minor myocardial cell injury....

journal_title：European heart journal

authors： Hamm CW

更新日期：1998-11-01 00:00:00

abstract：AIMS:Our objectives were (i) to compare the discriminatory performance of the Thrombolysis in Myocardial Infarction risk score (TIMI RS), Platelet glycoprotein IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin Therapy risk score (PURSUIT RS), and Global Registry of Acute Cardiac Events risk score (GRAC...

journal_title：European heart journal

authors： Yan AT,Yan RT,Tan M,Casanova A,Labinaz M,Sridhar K,Fitchett DH,Langer A,Goodman SG

更新日期：2007-05-01 00:00:00

abstract：AIMS:The aim is to compare the coronary risk chart published by the European Task Force for Prevention of Coronary Heart Disease and produced using a Framingham risk function, with a risk function derived from an Italian population study. METHODS AND RESULTS:Coronary risk function in this study was the result of longi...

journal_title：European heart journal

authors： Menotti A,Puddu PE,Lanti M

更新日期：2000-03-01 00:00:00