Association of cyclooxygenase-2 genetic variant with cardiovascular disease.

abstract：AIMS:Mitral regurgitation (MR) following an acute myocardial infarction (AMI) confers an adverse prognosis during long-term follow-up. There are no studies evaluating the influence of pre-AMI MR in the short- and long-term prognosis of such patients. Our aim was to assess the prognostic value of pre-AMI MR in the short...

journal_title：European heart journal

authors： Zamorano J,de Isla LP,Oliveros L,Almería C,Rodrigo JL,Aubele A,Banchs J,Macaya C

更新日期：2005-02-01 00:00:00

abstract：AIMS:Cardiomyopathy produces significant mortality in patients with Friedreich ataxia (FA), a genetic disorder that produces intra-mitochondrial iron accumulation. We sought to test the hypothesis that abnormal myocardial perfusion reserve and fibrosis represent early manifestations of cardiomyopathy. METHODS AND RESU...

journal_title：European heart journal

authors： Raman SV,Phatak K,Hoyle JC,Pennell ML,McCarthy B,Tran T,Prior TW,Olesik JW,Lutton A,Rankin C,Kissel JT,Al-Dahhak R

更新日期：2011-03-01 00:00:00

abstract：AIMS:The ESC/ACC redefined myocardial infarction as any amount of necrosis caused by ischaemia. The aim of this study was to describe the management and outcomes using 'real-world' data taking the new definition of acute myocardial infarction into account. METHODS AND RESULTS:A total of 2,151 consecutive patients (76....

journal_title：European heart journal

authors： Montalescot G,Dallongeville J,Van Belle E,Rouanet S,Baulac C,Degrandsart A,Vicaut E,OPERA Investigators.

更新日期：2007-06-01 00:00:00

abstract：:In 13 patients with chronic stable angina, left ventricular pressures were measured by catheter-tip micromanometer, and left cineventriculography was performed at matched atrial paced rates before and 20 min after administration of intravenous gallopamil (3 mg). Mean plasma concentration of gallopamil at the second ha...

journal_title：European heart journal

authors： Di Mario C,Iavernaro A,Cucchini F

更新日期：1991-09-01 00:00:00

abstract：:Aims To assess whether coronary flow velocity reserve following stent implantation is predictive of the subsequent need of target lesion revascularization. Methods and Results The outcome was examined of 417 patients enrolled in a multicentre prospective randomized study (DESTINI), who received a successful single ves...

journal_title：European heart journal

authors： Nishida T,Di Mario C,Kern MJ,Anderson TJ,Moussa I,Bonan R,Muramatsu T,Jain AC,Suarez de Lezo J,Cho SY,Meredith IT,Moses JW,Colombo A

更新日期：2002-02-01 00:00:00

abstract：Aims:Pulmonary hypertension (PH) and pulmonary vascular disease (PVD) are common and associated with adverse outcomes in heart failure with preserved ejection fraction (HFpEF). Little is known about the impact of PVD on the pathophysiology of exercise intolerance. Methods and results:Heart failure with preserved eject...

journal_title：European heart journal

authors： Gorter TM,Obokata M,Reddy YNV,Melenovsky V,Borlaug BA

更新日期：2018-08-07 00:00:00

abstract：:Patients who have an accessory pathway (AP) of atrioventricular (AV) conduction may develop circus movement tachycardia otherwise known as atrioventricular re-entrant tachycardia (AVRT). Orthodromic AVRT is the most common form. It occurs as a result of antegrade conduction through the normal AV conduction system and ...

journal_title：European heart journal

authors： Obel OA,Camm AJ

更新日期：1998-05-01 00:00:00

abstract：:Both epidemiological studies and intervention trials support an important role of diet in reducing the risk of a variety of chronic diseases, including cardiovascular disease, and overall mortality. We discuss available evidence indicating that the generation of a pro-inflammatory milieu might be one mechanism through...

journal_title：European heart journal

authors： Esposito K,Giugliano D

更新日期：2006-01-01 00:00:00

abstract：AIMS:Support with left ventricular assist devices (LVAD) improves cardiac performance in patients with end-stage heart failure. In some cases this strategy, combined with pharmacological treatment, has led to a clinical improvement which remained after LVAD explant. This study defines changes in Ca handling at the cell...

journal_title：European heart journal

authors： Terracciano CM,Harding SE,Adamson D,Koban M,Tansley P,Birks EJ,Barton PJ,Yacoub MH

更新日期：2003-07-01 00:00:00

abstract：AIMS:This is a prospective, randomized study comparing transvenous cryoablation with radiofrequency (RF) ablation of atrioventricular nodal re-entrant tachycardia (AVNRT). METHODS AND RESULTS:In this pilot trial, 200 patients with AVNRT were randomized to undergo cryoablation or RF ablation of the slow pathway. A 7 Fr...

journal_title：European heart journal

authors： Zrenner B,Dong J,Schreieck J,Deisenhofer I,Estner H,Luani B,Karch M,Schmitt C

更新日期：2004-12-01 00:00:00

abstract：AIMS:The presence of residual thrombus following fibrinolytic therapy for ST-segment elevation myocardial infarction (STEMI) may predispose to greater embolization and microvascular dysfunction. METHODS AND RESULTS:We hypothesized that even in the presence of a patent epicardial artery, residual thrombus would be asso...

journal_title：European heart journal

authors： Kirtane AJ,Vafai JJ,Murphy SA,Aroesty JM,Sabatine MS,Cannon CP,Gibson CM,TIMI Study Group.

更新日期：2006-09-01 00:00:00

abstract：AIMS:We sought to investigate the effect of adenosine pretreatment on the incidence of myonecrosis after non-urgent percutaneous coronary intervention (PCI). METHODS AND RESULTS:This was a prospective, randomized, open-label study. Patients who were scheduled for non-urgent PCI in de novo native coronary arteries were...

journal_title：European heart journal

authors： Lee CH,Low A,Tai BC,Co M,Chan MY,Lim J,Lim YT,Tan HC

更新日期：2007-01-01 00:00:00

abstract：:Increased QT dispersion, which has been proposed as a marker of ventricular repolarization inhomogeneity, may predispose to ventricular arrhythmias. Data on QT dispersion in patients with congestive heart failure are scarce. In this study, conventional 12-lead ECGs were recorded in 135 consecutive patients with conges...

journal_title：European heart journal

authors： Fei L,Goldman JH,Prasad K,Keeling PJ,Reardon K,Camm AJ,McKenna WJ

更新日期：1996-02-01 00:00:00

abstract：:Temporal signal averaging of the surface QRS (V1 + V3 + V5) was performed in 16 patients with arrhythmogenic right ventricular dysplasia and in 16 normal subjects. The differences between ARVD patients and normals were large for the filtered QRS duration (FQRSd) (146.2 +/- 18.9 ms vs. 91.8 +/- 4.1 ms, P less than 0.00...

journal_title：European heart journal

authors： Blomström-Lundqvist C,Hirsch I,Olsson SB,Edvardsson N

更新日期：1988-03-01 00:00:00

abstract：:Since fatty acids provide the majority of myocardial energy requirements under basal conditions, an alteration in the global or regional utilization of these substrates may be an early indicator of myocardial disease. To determine areas of potential clinical utility of fatty acid imaging, we synthesized a radioiodinat...

journal_title：European heart journal

authors： Livni E,Elmaleh DR,Barlai-Kovach MM,Goodman MM,Knapp FF Jr,Strauss HW

更新日期：1985-08-01 00:00:00

abstract：AIMS:Habitual cigarette smokers, paradoxically, present improved short-term prognosis after acute myocardial infarction, a phenomenon often termed "smoker's paradox". We sought to examine cigarette smokers' post-infarction survival advantage in a countrywide survey of unselected, consecutive patients presenting with ac...

journal_title：European heart journal

authors： Andrikopoulos GK,Richter DJ,Dilaveris PE,Pipilis A,Zaharoulis A,Gialafos JE,Toutouzas PK,Chimonas ET

更新日期：2001-05-01 00:00:00

abstract：:In this double-blind placebo-controlled study with enalapril, 74 patients with acute myocardial infarction were followed at 0, 7, 30, 60 and 180 days after the event. Platelets and leukocytes were activated during the first 7 days. During the 6-month period fibrinogen, leukocytes, elastase, and B beta 30-43 remained e...

journal_title：European heart journal

authors： Sylvén C,Hagerman I,Karlberg KE,Chen J,Wallin R,Eneroth P,Bergström K,Saldeen T

更新日期：1995-12-01 00:00:00

abstract：AIMS:Treatment of atrial fibrillation remains a major clinical challenge owing to the limited efficacy and safety of anti-arrhythmic drugs, particularly in patients with structural heart disease. METHODS AND RESULTS:To evaluate the efficacy of azimilide, a new class III anti-arrhythmic drug, we studied 658 patients wi...

journal_title：European heart journal

authors： Lombardi F,Borggrefe M,Ruzyllo W,Lüderitz B,A-COMET-II Investigators.

更新日期：2006-09-01 00:00:00

abstract：:The slope and pressure half-time of the aortic regurgitant velocity spectrum have been used as non-invasive markers of regurgitant severity. Recent in vitro and theoretical work, however, has suggested a confounding effect of systemic vascular resistance and left ventricular compliance on these parameters. To study th...

journal_title：European heart journal

authors： Griffin BP,Flachskampf FA,Reimold SC,Lee RT,Thomas JD

更新日期：1994-05-01 00:00:00

abstract：AIMS:Release of progenitor cells is observed during inflammatory conditions and contributes to neovascularization. We, therefore, sought to investigate the relationship of circulating progenitor cells and interleukin (IL)-8 in acute myocardial infarction (AMI). METHODS AND RESULTS:From patients with stable angina and ...

journal_title：European heart journal

authors： Schömig K,Busch G,Steppich B,Sepp D,Kaufmann J,Stein A,Schömig A,Ott I

更新日期：2006-05-01 00:00:00

abstract：AIM:Short-term psychological stress is associated with an immediate physiological response and may be associated with a transiently higher risk of cardiovascular events. The aim of this study was to determine whether brief episodes of anger trigger the onset of acute myocardial infarction (MI), acute coronary syndromes...

journal_title：European heart journal

authors： Mostofsky E,Penner EA,Mittleman MA

更新日期：2014-06-01 00:00:00

abstract：AIMS:To perform a retrospective analysis of subgroups of patients enrolled into the European Myocardial Infarct Amiodarone Trial (EMIAT) in order to identify patients who might benefit from prophylactic amiodarone treatment and patients in whom amiodarone might be harmful. METHODS:Baseline characteristics of the 1486 ...

journal_title：European heart journal

authors： Janse MJ,Malik M,Camm AJ,Julian DG,Frangin GA,Schwartz PJ

更新日期：1998-01-01 00:00:00

abstract：:Left ventricular (LV) filling as assessed by Doppler transmitral flow velocity measurements was studied in 20 male patients with coronary artery disease (CAD) and in 18 normal individuals. Stroke volume, blood pressure and heart rate in the two groups were not significantly different. Compared to normals, the ratio be...

journal_title：European heart journal

authors： Myreng Y,Ihlen H,Nitter-Hauge S

更新日期：1988-11-01 00:00:00

abstract：:The effect of sublingually administered nitroglycerin (0.5 mg) on distribution of blood volume in 16 patients with congestive heart failure (NYHA class II and III), randomly assigned to placebo (N = 8) or nitroglycerin (N = 8) was studied 20 minutes after in vivo labelling of red blood cells with 99m-Tc pertechnetate....

journal_title：European heart journal

authors： Schneider AJ,Teule GJ,Groeneveld AB,Nauta J,Luth WJ,Thijs LG

更新日期：1987-10-01 00:00:00

abstract：AIMS:To compare effects of heparin and hirudin on biochemical markers of coagulation. METHODS AND RESULTS:Patients (n=395) with unstable angina or myocardial infarction without ST elevation were randomized to a 72-h infusion of one of three regimens: unfractionated heparin (bolus of 5000 IU followed by an infusion of ...

journal_title：European heart journal

authors： Flather MD,Weitz JI,Yusuf S,Pogue J,Sussex B,Campeau J,Gill J,Schuld R,Joyner CD,Morris AL,Lai C,Théroux P,Marquis JF,Chan YK,Venkatesh G,Jessel A

更新日期：2000-09-01 00:00:00

abstract：AIMS:Elevated blood pressure (EBP) is the most prevalent and potentially modifiable risk factor for AF, yet little is known of its atrial effects. We aimed to characterize the atrial electrical and structural changes in a chronic ovine model of EBP after prenatal corticosteroid exposure. METHODS AND RESULTS:Twelve she...

journal_title：European heart journal

authors： Kistler PM,Sanders P,Dodic M,Spence SJ,Samuel CS,Zhao C,Charles JA,Edwards GA,Kalman JM

更新日期：2006-12-01 00:00:00

abstract：:A necessary part of the strategy of modification of hypercholesterolaemia to prevent coronary heart disease (CHD) is the detection and treatment, by diet or by drugs, of high risk individuals. There are several drawbacks to this approach: (1) the cost of screening to find individuals at risk and of monitoring by physi...

journal_title：European heart journal

authors： Marmot MG

更新日期：1987-08-01 00:00:00

abstract：:Heart rate and age are independent variables associated with the pattern of normal left ventricular filling. Since heart rate variability also varies with age, the relationship between these and left ventricular filling in normal subjects was assessed. In 31 subjects (age range 21 to 71 years), power spectral analysis...

journal_title：European heart journal

authors： Finkelhor RS,Karwa P,Kaufman ES,Bahler RC

更新日期：1995-11-01 00:00:00

abstract：:Stephan Achenbach reviews the history of coronary computer tomography angiography and discusses its further evolution. ...

journal_title：European heart journal

authors： Achenbach S

更新日期：2016-02-21 00:00:00

abstract：:The concentration of cholesterol in peripheral lymph is roughly one tenth of that in the blood plasma of the same subject. In lymph, there is virtually no very low density lipoprotein (VLDL), probably due to low permeability of the vascular endothelium for particles of this size. More than 95% of apo B-containing lipo...

journal_title：European heart journal

authors： Reichl D

更新日期：1990-08-01 00:00:00