STEMI and NSTEMI: are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry).

abstract：:Two patients with myocardial bridging of the left anterior descending coronary artery associated with myocardial infarction are described. One of them died from acute cerebral emboli related to cardiac thrombosis in a left ventricular aneurysm. The other died suddenly while sleeping. Both patients were found to have a...

journal_title：European heart journal

authors： Bestetti RB,Costa RS,Zucolotto S,Oliveira JS

更新日期：1989-06-01 00:00:00

abstract：:In this double-blind placebo-controlled study with enalapril, 74 patients with acute myocardial infarction were followed at 0, 7, 30, 60 and 180 days after the event. Platelets and leukocytes were activated during the first 7 days. During the 6-month period fibrinogen, leukocytes, elastase, and B beta 30-43 remained e...

journal_title：European heart journal

authors： Sylvén C,Hagerman I,Karlberg KE,Chen J,Wallin R,Eneroth P,Bergström K,Saldeen T

更新日期：1995-12-01 00:00:00

abstract：:As a rule, left ventricular relaxation is impaired in patients with coronary artery disease and congestive heart failure. In addition, the passive elastic properties in early and late diastole change when the ventricle dilates. Diastolic properties of the left ventricle were studied in 11 patients with congestive hear...

journal_title：European heart journal

authors： Baur LH,Schipperheyn JJ,Cats VM,van der Wall EE,Baan J,van Dijk AD,Bruschke AV

更新日期：1992-11-01 00:00:00

abstract：AIMS:Obstructive sleep apnoea (OSA) is highly prevalent in patients with chronic heart failure (CHF) and may contribute to CHF progression. We aimed to determine whether treatment of OSA with continuous positive airway pressure (CPAP) would improve subjective and objective measures of heart failure severity in patients...

journal_title：European heart journal

authors： Smith LA,Vennelle M,Gardner RS,McDonagh TA,Denvir MA,Douglas NJ,Newby DE

更新日期：2007-05-01 00:00:00

abstract：:Myocardial protection and the control of ischemic injury has been highly successful clinically in the field of cardiac surgery where hearts are made globally ischemic. By contrast, protection of the regionally ischemic myocardium, as found during evolving myocardial infarction, has been less successful and, despite nu...

journal_title：European heart journal

authors： Hearse DJ

更新日期：1983-05-01 00:00:00

abstract：AIMS:In this study, we compared the clinical outcomes of elderly patients with unprotected left main coronary artery (ULMCA) stenosis treated with either coronary artery bypass grafting (CABG) or drug-eluting stent (DES). METHODS AND RESULTS:From January 2003 to April 2006, 259 patients with ULMCA stenosis and age > o...

journal_title：European heart journal

authors： Palmerini T,Barlocco F,Santarelli A,Bacchi-Reggiani L,Savini C,Baldini E,Alessi L,Ruffini M,Di Credico G,Piovaccari G,Di Bartolomeo R,Marzocchi A,Branzi A,De Servi S

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:The primary objectives of this study were to assess the feasibility of temperature-controlled radiofrequency catheter ablation of left and right sided manifest accessory pathways in patients with Wolff-Parkinson-White syndrome and to gain more insights into biophysical aspects of temperature-controlled cathe...

journal_title：European heart journal

authors： Willems S,Chen X,Kottkamp H,Hindricks G,Haverkamp W,Rotman B,Shenasa M,Breithardt G,Borggrefe M

更新日期：1996-03-01 00:00:00

abstract：:The value of quantitative assessment of coronary artery dimensions at the site of the most critical coronary stenosis was assessed by comparison with the correspondent reactive hyperaemia as measured by digital subtraction angiography and with the functional results. Thirty-two coronary lesions were analysed and flow ...

journal_title：European heart journal

authors： Legrand V,Mancini GB,Le Free MT,Vogel RA

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Patients with known or suspected coronary disease are often investigated to facilitate risk assessment. We sought to examine the cost-effectiveness of strategies based on exercise echocardiography and exercise electrocardiography. METHODS AND RESULTS:We studied 7656 patients undergoing exercise testing; of ...

journal_title：European heart journal

authors： Marwick TH,Shaw L,Case C,Vasey C,Thomas JD

更新日期：2003-06-01 00:00:00

abstract：:Chronically ischaemic myocardium from patients with coronary heart disease was investigated by light and electron microscopy using tissue biopsies taken during cardiac surgery. Light microscopy showed a significantly increased amount of fibrotic material, cell size was variable. By electron microscopy, the most obviou...

journal_title：European heart journal

authors： Schaper J

更新日期：1988-01-01 00:00:00

abstract：:The aim of the present investigation was to evaluate the type and the incidence of cardiac arrhythmias and ischaemic events in patients suffering from testicular cancer and submitted to combination chemotherapy with cisplatin, bleomycin and vinblastine (PVB) or etoposide (PEB). Forty-seven patients took part in the st...

journal_title：European heart journal

authors： Villani F,Misrachi D,Galimberti M

更新日期：1994-11-01 00:00:00

abstract：AIMS:Growth-differentiation factor-15 (GDF-15) has emerged as a biomarker of increased mortality and recurrent myocardial infarction (MI) in patients diagnosed with non-ST-elevation acute coronary syndrome. We explored the usefulness of GDF-15 for early risk stratification in 479 unselected patients with acute chest pa...

journal_title：European heart journal

authors： Eggers KM,Kempf T,Allhoff T,Lindahl B,Wallentin L,Wollert KC

更新日期：2008-10-01 00:00:00

abstract：AIMS:The aim of this study was to evaluate (1) homocysteinemia and the prevalence of the C677T MTHFR polymorphism in Marfan patients and (2) whether the severity of cardiovascular manifestations is associated with homocysteinemia and/or C677T polymorphism. METHODS AND RESULTS:We studied 107 patients subdivided into th...

journal_title：European heart journal

authors： Giusti B,Porciani MC,Brunelli T,Evangelisti L,Fedi S,Gensini GF,Abbate R,Sani G,Yacoub M,Pepe G

更新日期：2003-11-01 00:00:00

abstract：:The reperfusion era has dramatically and irrevocably transformed the management of ST-segment elevation myocardial infarction (STEMI). For the patient treated with fibrinolysis as the initial reperfusion strategy, subsequent options which are the subject of some controversy and the focus of this review are (i) facilit...

journal_title：European heart journal

authors： Kiernan TJ,Ting HH,Gersh BJ

更新日期：2007-07-01 00:00:00

abstract：:Diagnosis of myocarditis has improved with the application of new techniques such as immunohistochemistry, polymerase chain reaction, in situ hybridization and Southern blot in endomyocardial biopsies. Treatment of inflammatory heart disease is still difficult and not yet validated by a study with patient numbers suff...

journal_title：European heart journal

authors： Maisch B,Hufnagel G,Schönian U,Hengstenberg C

更新日期：1995-12-01 00:00:00

abstract：:This state-of-the-art review aims to provide an up-to-date look at breakthrough omic technologies that are helping to unravel heart failure (HF) disease mechanisms and heterogeneity. Genomics, transcriptomics, proteomics, and metabolomics in HF are reviewed in depth. In addition, there is a thorough, expert discussion...

journal_title：European heart journal

authors： Bayes-Genis A,Liu PP,Lanfear DE,de Boer RA,González A,Thum T,Emdin M,Januzzi JL

更新日期：2020-09-21 00:00:00

abstract：:Food constituents can either promote cardiovascular health or serve in its demise. In view of the lack of more effective pharmacological interventions in cardiovascular disease (CVDs), attention has focused on the potential protective effects of diet. Food components and their metabolites are emerging as major regulat...

journal_title：European heart journal

authors： Lionetti V,Tuana BS,Casieri V,Parikh M,Pierce GN

更新日期：2019-02-14 00:00:00

abstract：:The optimal length of clopidogrel therapy in patients with acute coronary syndromes or in those who have undergone percutaneous coronary intervention (PCI) remains controversial. We therefore sought to determine the risk of both perioperative and premature discontinuation of clopidogrel. PubMed and EMBASE databases we...

journal_title：European heart journal

authors： Gaglia MA Jr,Waksman R

更新日期：2011-10-01 00:00:00

abstract：:The Alliance for Biomedical Research in Europe, co-founded by the European Society of Cardiology, has persuaded the European Parliament to move towards European Union-wide means of better directing and coordinating biomedical research, from the laboratory bench to the marketplace. ...

journal_title：European heart journal

authors： Shurlock B

更新日期：2014-04-01 00:00:00

abstract：AIM:Unstable coronary artery disease (CAD) is a multifactorial disease involving both thrombotic and inflammatory processes. We have assessed the time-course and the influence of thrombin inhibitors on changes in fibrinogen and C-reactive protein levels, and their relation to myocardial ischaemia in unstable CAD. METH...

journal_title：European heart journal

authors： Oldgren J,Wallentin L,Grip L,Linder R,Nørgaard BL,Siegbahn A

更新日期：2003-01-01 00:00:00

abstract：AIMS:There have been substantial declines in cerebrovascular disease mortality across much of Europe, mirroring trends in deaths from cardiovascular disease as a whole. No study has investigated trends in cerebrovascular disease, and its subtypes within all European countries. This study aimed to examine sex-specific t...

journal_title：European heart journal

authors： Shah R,Wilkins E,Nichols M,Kelly P,El-Sadi F,Wright FL,Townsend N

更新日期：2019-03-01 00:00:00

abstract：:Nucleic acid-based therapeutics are currently developed at large scale for prevention and management of cardiovascular diseases (CVDs), since: (i) genetic studies have highlighted novel therapeutic targets suggested to be causal for CVD; (ii) there is a substantial recent progress in delivery, efficacy, and safety of ...

journal_title：European heart journal

authors： Landmesser U,Poller W,Tsimikas S,Most P,Paneni F,Lüscher TF

更新日期：2020-10-21 00:00:00

abstract：AIMS:We investigated the influence of type one cannabinoid receptor (CB1) deficiency on acute heart failure (AHF) and the underlying mechanism. Acute heart failure syndrome is an important clinical problem because of its high morbidity and mortality rates. Activation of CB1 induces vascular dilation and reinforces the ...

journal_title：European heart journal

authors： Liao Y,Bin J,Asakura M,Xuan W,Chen B,Huang Q,Xu D,Ledent C,Takashima S,Kitakaze M

更新日期：2012-12-01 00:00:00

abstract：:Thrombolytic therapy is a practical, effective approach to the management of acute myocardial infarction that is widely used in Europe today. Early European trials demonstrated a clear reduction in mortality in patients who received thrombolytic therapy compared with those given conventional treatment. The findings of...

journal_title：European heart journal

authors： Vahanian A

更新日期：1996-09-01 00:00:00

abstract：:In 13 patients with chronic stable angina, left ventricular pressures were measured by catheter-tip micromanometer, and left cineventriculography was performed at matched atrial paced rates before and 20 min after administration of intravenous gallopamil (3 mg). Mean plasma concentration of gallopamil at the second ha...

journal_title：European heart journal

authors： Di Mario C,Iavernaro A,Cucchini F

更新日期：1991-09-01 00:00:00

abstract：AIMS:The importance of heart rate in the pathophysiology of heart failure with reduced LVEF has recently attracted attention. In particular, the findings of the Systolic Heart failure treatment with the I(f) inhibitor ivabradine Trial (SHIFT) have put special emphasis on heart rate reduction with ivabradine for improve...

journal_title：European heart journal

authors： Castagno D,Petrie MC,Claggett B,McMurray J

更新日期：2012-05-01 00:00:00

abstract：AIMS:To examine the extent of platelet inhibition by prasugrel vs. clopidogrel in a TRITON-TIMI 38 substudy. METHODS AND RESULTS:TRITON-TIMI 38 randomized acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI) to prasugrel or standard dose clopidogrel. Selected sites prospectively e...

journal_title：European heart journal

authors： Michelson AD,Frelinger AL 3rd,Braunwald E,Downey WE,Angiolillo DJ,Xenopoulos NP,Jakubowski JA,Li Y,Murphy SA,Qin J,McCabe CH,Antman EM,Wiviott SD,TRITON-TIMI 38 Investigators.

更新日期：2009-07-01 00:00:00

abstract：:The purpose of this study was to evaluate the accuracy of adenosine Tc-99m sestamibi single photon emission computed tomography (SPECT) in the detection of jeopardized myocardium early after acute myocardial infarction. Coronary arteriography and myocardial scintigraphy were performed in 50 consecutive patients with a...

journal_title：European heart journal

authors： Claeys MJ,Vrints CJ,Krug B,Bosmans JM,Blockx PP,Bossaert LL,Snoeck JP

更新日期：1995-09-01 00:00:00

abstract：AIMS:The optimal timing of intervention in non-ST-elevation myocardial infarction (NSTEMI) remains uncertain. The aim of this multicentre trial was to assess whether an immediate invasive approach is superior to an early invasive or a selective invasive approach with respect to reduction of large infarction. METHODS A...

journal_title：European heart journal

authors： Thiele H,Rach J,Klein N,Pfeiffer D,Hartmann A,Hambrecht R,Sick P,Eitel I,Desch S,Schuler G,LIPSIA-NSTEMI Trial Group.

更新日期：2012-08-01 00:00:00

abstract：AIMS:The aim of this study is to simultaneously evaluate the incremental prognostic value of multiple cardiac biomarkers reflecting different underlying pathophysiological processes in a well-characterized population of patients with non-ST-segment acute coronary syndrome (NSTE-ACS). METHODS AND RESULTS:We measured ca...

journal_title：European heart journal

authors： Scirica BM,Sabatine MS,Jarolim P,Murphy SA,de Lemos JL,Braunwald E,Morrow DA

更新日期：2011-03-01 00:00:00