Comparison of the Framingham risk function-based coronary chart with risk function from an Italian population study.

abstract：:Some studies provide a link between the width of QRS complexes and late potentials occurring at the end of the QRS complex in signal-averaged recordings. The purpose of this study was to compare three methods of QRS duration measurement: the conventional 12 lead ECG, the Frank vectorcardiogram (VCG) and the signal-ave...

journal_title：European heart journal

authors： Brembilla-Perrot B

更新日期：1994-01-01 00:00:00

abstract：:In the blood-vessel wall, the endothelium plays a key functional role by generating several substances that modulate vascular smooth muscle tone, as well as growth, and platelet function. This review focuses on the role of the endothelial L-arginine/nitric oxide signal transduction pathway in the maintenance of vascul...

journal_title：European heart journal

authors： Cosentino F,Lüscher TF

更新日期：1995-11-01 00:00:00

abstract：:Large-scale trials have demonstrated a consistent mortality reduction from angiotensin converting enzyme (ACE) inhibitor therapy for chronic heart failure. Nonetheless, the pharmacologic and physiologic mechanisms of this favourable affect and the appropriate target population remain controversial. ACE inhibitors exer...

journal_title：European heart journal

authors： Cohn JN

更新日期：1995-12-01 00:00:00

abstract：:ST segment monitoring by Holter ECG was conducted in 80 consecutive patients 2-4 weeks before aortocoronary bypass surgery and three weeks and six months after surgery. Preoperatively, all patients were under maximal medical therapy. In 31 out of 80 patients medical therapy could be stopped and thus 24-h ST monitoring...

journal_title：European heart journal

authors： Droste C,Lemmen S,Nitsche R,Betz P,Birnbaum D,Roskamm H

更新日期：1988-12-01 00:00:00

abstract：:This study was designed to evaluate the implantation of internal cardioverter/defibrillators under local anaesthesia by electrophysiologists and to compare this to our former experience of implants with general anaesthesia. Forty-seven internal cardioverter/defibrillators were implanted at our institution by electroph...

journal_title：European heart journal

authors： Schmitt C,Alt E,Plewan A,Schömig A

更新日期：1996-11-01 00:00:00

abstract：AIMS:The optimal timing of intervention in non-ST-elevation myocardial infarction (NSTEMI) remains uncertain. The aim of this multicentre trial was to assess whether an immediate invasive approach is superior to an early invasive or a selective invasive approach with respect to reduction of large infarction. METHODS A...

journal_title：European heart journal

authors： Thiele H,Rach J,Klein N,Pfeiffer D,Hartmann A,Hambrecht R,Sick P,Eitel I,Desch S,Schuler G,LIPSIA-NSTEMI Trial Group.

更新日期：2012-08-01 00:00:00

abstract：:The transdermal nitroglycerin patches have been very successful nitrate formulations since their introduction in 1982. Nevertheless, considerable controversy regarding efficacy and tolerance has arisen. Nitroglycerin has multiple mechanisms of action in angina pectoris. Transdermal nitroglycerin in ointment formulatio...

journal_title：European heart journal

authors： Abrams J

更新日期：1989-05-01 00:00:00

abstract：AIM:Heart disease is recognized as a consequence of dysregulation of cardiac gene regulatory networks. Previously, unappreciated components of such networks are the long non-coding RNAs (lncRNAs). Their roles in the heart remain to be elucidated. Thus, this study aimed to systematically characterize the cardiac long no...

journal_title：European heart journal

authors： Ounzain S,Micheletti R,Beckmann T,Schroen B,Alexanian M,Pezzuto I,Crippa S,Nemir M,Sarre A,Johnson R,Dauvillier J,Burdet F,Ibberson M,Guigó R,Xenarios I,Heymans S,Pedrazzini T

更新日期：2015-02-07 00:00:00

abstract：AIMS:Thrombin plays a key role in the clinical syndrome of unstable angina. We investigated the safety and efficacy of five dose levels of efegatran sulphate, a direct thrombin inhibitor, compared to heparin in patients with unstable angina. METHODS:Four hundred and thirty-two patients with unstable angina were enroll...

journal_title：European heart journal

authors： Klootwijk P,Lenderink T,Meij S,Boersma H,Melkert R,Umans VA,Stibbe J,Müller EJ,Poortermans KJ,Deckers JW,Simoons ML

更新日期：1999-08-01 00:00:00

abstract：AIMS:Emerging evidence indicates that nuclear receptors play a critical regulatory role in cardiovascular physiology/pathology. Recently, farnesoid-X-receptor (FXR), a member of the metabolic nuclear receptor superfamily, has been demonstrated to be expressed in vascular cells, with important roles in vascular physiolo...

journal_title：European heart journal

authors： Pu J,Yuan A,Shan P,Gao E,Wang X,Wang Y,Lau WB,Koch W,Ma XL,He B

更新日期：2013-06-01 00:00:00

abstract：:The effects of a single oral dose of nisoldipine, 10 mg, were investigated in two groups of patients. Firstly, the effects of nisoldipine on exercise left ventricular function were assessed in 20 patients with chronic stable angina and coronary disease. Secondly, the effects of nisoldipine on the left ventricular resp...

journal_title：European heart journal

authors： Dymond DS,Caplin JL,O'Keefe JC,Banim S

更新日期：1987-11-01 00:00:00

abstract：AIMS:Major bleeding after percutaneous coronary intervention (PCI) is an independent risk factor for early and late mortality. We developed and validated a risk score predictive of major bleeding after PCI using the femoral approach. METHODS AND RESULTS:Baseline clinical and procedural variables from two contemporary,...

journal_title：European heart journal

authors： Nikolsky E,Mehran R,Dangas G,Fahy M,Na Y,Pocock SJ,Lincoff AM,Stone GW

更新日期：2007-08-01 00:00:00

abstract：:It is now recognised after many years of speculation regarding the role of mammalian atria in the direct regulation of intravascular volume, that atrial myocites produce a peptide hormone that results in natriuresis and diuresis, under the condition of atrial distention. This atrial natriuretic factor (ANF) is secrete...

journal_title：European heart journal

authors： Cody RJ,Atlas SA,Laragh JH

更新日期：1988-06-01 00:00:00

abstract：:Increased QT dispersion, which has been proposed as a marker of ventricular repolarization inhomogeneity, may predispose to ventricular arrhythmias. Data on QT dispersion in patients with congestive heart failure are scarce. In this study, conventional 12-lead ECGs were recorded in 135 consecutive patients with conges...

journal_title：European heart journal

authors： Fei L,Goldman JH,Prasad K,Keeling PJ,Reardon K,Camm AJ,McKenna WJ

更新日期：1996-02-01 00:00:00

abstract：AIMS:The role of cardiovascular risk factors and atherosclerosis in the aetiology of abdominal aortic aneurysms is not well understood. The aim of this study was to determine the association between atherosclerosis and aortic aneurysm in the general population and the extent to which cardiovascular risk factors might i...

journal_title：European heart journal

authors： Lee AJ,Fowkes FG,Carson MN,Leng GC,Allan PL

更新日期：1997-04-01 00:00:00

abstract：:Angiotensin II (AII) has been implicated as an important factor in the pathophysiology of heart diseases. Following the recent identification of two subtypes of the AII receptor in cardiac tissue of animals, we investigated the possible occurrence of these, or similar, subtypes in human atrial tissue. In right-atrial ...

journal_title：European heart journal

authors： Rogg H,de Gasparo M,Graedel E,Stulz P,Burkart F,Eberhard M,Erne P

更新日期：1996-07-01 00:00:00

abstract：:The impulses coming from the sinus node synchronically penetrate the AV node via the crista terminalis and inter-atrial septum. Studies in superfused rabbit AV preparations suggest that the crista terminalis is a more effective input than the inter-atrial septum, and that the summation of both inputs facilitates AV no...

journal_title：European heart journal

authors： Sanchis J,Chorro FJ,Such L,Matamoros J,Monmeneu JV,Cortina J,López Merino V

更新日期：1993-10-01 00:00:00

abstract：:The non-invasive quantification of mitral and aortic regurgitation using the left-to-right stroke count ratio (SCR) calculated with gated equilibrium radionuclide ventriculography (RNV), is affected by the overlap of atria and ventricles and the consequent difficult definition of the ventricular regions of interest (R...

journal_title：European heart journal

authors： Sciagrà R,Voth E,Tebbe U,Schicha H,Neuhaus KL

更新日期：1987-10-01 00:00:00

abstract：AIMS:To estimate the incidence of dementia after the first atrial fibrillation (AF), and its impact on survival in a community-based cohort. METHODS AND RESULTS:Olmsted County, Minnesota adult residents diagnosed with first AF during 1986-2000 were identified, and followed until 2004. The primary outcome was new detec...

journal_title：European heart journal

authors： Miyasaka Y,Barnes ME,Petersen RC,Cha SS,Bailey KR,Gersh BJ,Casaclang-Verzosa G,Abhayaratna WP,Seward JB,Iwasaka T,Tsang TS

更新日期：2007-08-01 00:00:00

abstract：:Acute myocardial infarction remains the principal cause of death in people aged over 40 years, despite the reductions in coronary heart disease (CHD) mortality that have been observed over the past 25 years in many European countries. Consequently, there is considerable potential to decrease further the risk of cardio...

journal_title：European heart journal

authors： Shepherd J

更新日期：1998-10-01 00:00:00

abstract：:We studied the effects of angiotensin (Ang) I and II in a variety of isolated human cardiac tissues contracting under physiological conditions (37 degrees C, 60 beats.min-1). Ang I and II consistently increased the peak developed force of human atrial muscles by 30-40%, an effect that was completely blocked by 10(-6) ...

journal_title：European heart journal

authors： Holubarsch C,Schmidt-Schweda S,Knorr A,Duis J,Pieske B,Ruf T,Fasol R,Hasenfuss G,Just H

更新日期：1994-12-01 00:00:00

abstract：:Large-scale randomized clinical trials have established the efficacy of cholesterol-lowering, blood pressure-lowering, and anti-platelet therapy to prevent cardiovascular diseases. A challenge for clinicians is to apply group-level evidence from these trials to individual patients. Trials typically report a single tre...

journal_title：European heart journal

authors： van der Leeuw J,Ridker PM,van der Graaf Y,Visseren FL

更新日期：2014-04-01 00:00:00

abstract：:Diastolic heart disease is common and appears to be the primary abnormality in a substantial proportion of all patients with CHF. The epidemiology and natural history of the condition appears different to that of systolic heart failure, resulting in significant morbidity although contributing little to overall mortali...

journal_title：European heart journal

authors： Wheeldon NM,Clarkson P,MacDonald TM

更新日期：1994-12-01 00:00:00

abstract：:Chronically ischaemic myocardium from patients with coronary heart disease was investigated by light and electron microscopy using tissue biopsies taken during cardiac surgery. Light microscopy showed a significantly increased amount of fibrotic material, cell size was variable. By electron microscopy, the most obviou...

journal_title：European heart journal

authors： Schaper J

更新日期：1988-01-01 00:00:00

abstract：:Thiazide diuretics are efficacious, either as monotherapy or in combination with other antihypertensive drugs. They reduce blood pressure in a high percentage of hypertensive patients with minimal subjective side effects. There is increasing evidence that the use of diuretics, singly or in combination, will reduce mor...

journal_title：European heart journal

authors： Moser M

更新日期：1992-12-01 00:00:00

abstract：AIMS:A potential role for cardiovascular disease (CVD) risk factors in the aetiology of suicide has not been comprehensively examined. In addition to being small in scale and poorly characterized, existing studies very rarely sample Asian populations in whom risk factor-suicide relationships may plausibly differ to Cau...

journal_title：European heart journal

authors： Jee SH,Kivimaki M,Kang HC,Park IS,Samet JM,Batty GD

更新日期：2011-11-01 00:00:00

abstract：:To assess the prevalence of asymmetric septal hypertrophy (ASH) in hypertensive patients, 613 echocardiographic examinations performed over a period of one year were reviewed. Asymmetric septal hypertrophy (defined by an echocardiographic interventricular septum to left ventricular free wall thickness ratio of greater...

journal_title：European heart journal

authors： Wicker P,Roudaut R,Haissaguere M,Villega-Arino P,Clementy J,Dallocchio M

更新日期：1983-11-01 00:00:00

abstract：AIMS:Adenosine stress computed tomography myocardial perfusion imaging (CTP) is an emerging non-invasive method for detecting myocardial ischaemia. Its value when compared with fractional flow reserve (FFR), a highly accurate index of ischaemia, is unknown. Our aim was to determine the diagnostic accuracy of CTP and it...

journal_title：European heart journal

authors： Ko BS,Cameron JD,Meredith IT,Leung M,Antonis PR,Nasis A,Crossett M,Hope SA,Lehman SJ,Troupis J,DeFrance T,Seneviratne SK

更新日期：2012-01-01 00:00:00

abstract：AIMS:Carotid intima-media thickness (CIMT) and plaque information can improve coronary heart disease (CHD) risk prediction when added to traditional risk factors (TRF). However, obtaining adequate images of all carotid artery segments (A-CIMT) may be difficult. Of A-CIMT, the common carotid artery intima-media thicknes...

journal_title：European heart journal

authors： Nambi V,Chambless L,He M,Folsom AR,Mosley T,Boerwinkle E,Ballantyne CM

更新日期：2012-01-01 00:00:00

abstract：AIM:To describe the relative impact on survival of the delay from estimated time of collapse to call for an ambulance among patients who suffer from a bystander witnessed out of hospital cardiac arrest of a cardiac aetiology. METHODS:A majority of all ambulance organizations in Sweden (covering 85% of Sweden inhabitan...

journal_title：European heart journal

authors： Herlitz J,Engdahl J,Svensson L,Young M,Angquist KA,Holmberg S

更新日期：2003-10-01 00:00:00