Effects of nisoldipine on left ventricular function during exercise or cold pressor stress.

abstract：:The natriuretic peptides are important tools to establish diagnosis and prognosis in heart failure (HF). With application of therapies for HF, changes in both B-type natriuretic peptide (BNP) and its amino terminal cleavage fragment (NT-proBNP) parallel the benefits of the HF therapy applied. This dynamic nature of BN...

journal_title：European heart journal

authors： Troughton R,Michael Felker G,Januzzi JL Jr

更新日期：2014-01-01 00:00:00

abstract：:Clinical studies suggest that neutrophil activation during acute myocardial infarction (MI) aggravates tissue injury. Activated neutrophils are an important source of oxygen free radicals (OFR), the injurious effects of which are counteracted by endogenous antioxidants. We have previously shown in healthy subjects tha...

journal_title：European heart journal

authors： Herbaczyńska-Cedro K,K+osiewicz-Wasek B,Cedro K,Wasek W,Panczenko-Kresowska B,Wartanowicz M

更新日期：1995-08-01 00:00:00

abstract：AIMS:The obesity paradox refers to the epidemiological evidence that obesity compared with normal weight is associated with counter-intuitive improved health in a variety of disease conditions. The aim of this study was to investigate the relationship between body mass index (BMI) and mortality in patients with acute c...

journal_title：European heart journal

authors： Angerås O,Albertsson P,Karason K,Råmunddal T,Matejka G,James S,Lagerqvist B,Rosengren A,Omerovic E

更新日期：2013-02-01 00:00:00

abstract：:Alterations in the right ventricular function may or may not contribute to progressive cardiac dysfunction after left ventricular infarction. Ligation of the left coronary artery (LCAL) was lethal within 24 h for 25% of 100 rats, whereas none of 21 sham-operated rats died. No rats died during the following 4 weeks, af...

journal_title：European heart journal

authors： Christiansen EH,Tian R,Böttcher M,Andreasen F

更新日期：1993-11-01 00:00:00

abstract：:We studied the effects of angiotensin (Ang) I and II in a variety of isolated human cardiac tissues contracting under physiological conditions (37 degrees C, 60 beats.min-1). Ang I and II consistently increased the peak developed force of human atrial muscles by 30-40%, an effect that was completely blocked by 10(-6) ...

journal_title：European heart journal

authors： Holubarsch C,Schmidt-Schweda S,Knorr A,Duis J,Pieske B,Ruf T,Fasol R,Hasenfuss G,Just H

更新日期：1994-12-01 00:00:00

abstract：:Falipamil hydrochloride (AQA 39) is a new antiarrhythmic agent structurally related to verapamil. We evaluated the electrophysiologic properties of intravenous falipamil (1.5 mg kg-1 within 20 minutes) in 12 patients. The spontaneous cycle length was significantly (P less than 0.001) prolonged (+79 +/- 59 ms). Atriove...

journal_title：European heart journal

authors： Lévy S,Mètge M,Hilaire J,Cointe R,Bru P,Eychenne JL,Gérard R

更新日期：1987-11-01 00:00:00

abstract：AIM:We sought to evaluate the incidence and electrophysiological features of the local slow potential preceding the surface QRS complex (pre-QRS potential) which was detected more frequently at successful sites of catheter ablation of left parietal concealed accessory pathways, than at unsuccessful sites. METHODS AND ...

journal_title：European heart journal

authors： Miyauchi Y,Kobayashi Y,Ino T,Atarashi H

更新日期：1999-12-01 00:00:00

abstract：:Thiazide diuretics are efficacious, either as monotherapy or in combination with other antihypertensive drugs. They reduce blood pressure in a high percentage of hypertensive patients with minimal subjective side effects. There is increasing evidence that the use of diuretics, singly or in combination, will reduce mor...

journal_title：European heart journal

authors： Moser M

更新日期：1992-12-01 00:00:00

abstract：:In this study, the acute haemodynamic effects of angiotensin converting enzyme (ACE) inhibition with intravenous enalaprilat alone or in combination with preload restoration were determined in patients with severe heart failure complicating acute myocardial infarction. Ten patients with raised pulmonary arterial wedge...

journal_title：European heart journal

authors： Tohmo H,Karanko M,Korpilahti K

更新日期：1994-04-01 00:00:00

abstract：AIMS:To examine the extent of platelet inhibition by prasugrel vs. clopidogrel in a TRITON-TIMI 38 substudy. METHODS AND RESULTS:TRITON-TIMI 38 randomized acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI) to prasugrel or standard dose clopidogrel. Selected sites prospectively e...

journal_title：European heart journal

authors： Michelson AD,Frelinger AL 3rd,Braunwald E,Downey WE,Angiolillo DJ,Xenopoulos NP,Jakubowski JA,Li Y,Murphy SA,Qin J,McCabe CH,Antman EM,Wiviott SD,TRITON-TIMI 38 Investigators.

更新日期：2009-07-01 00:00:00

abstract：:The present study was designed to examine the effects of a new organic nitrate, teopranitol, in acute myocardial ischaemia. Adult cats were subjected to 5 h of myocardial ischaemia by permanent ligation of the left anterior descending coronary artery (LAD). Teopranitol (10 mg kg-1 X h) or physiological saline (vehicle...

journal_title：European heart journal

authors： Thiemermann C,Smith EF 3rd,Schrör K

更新日期：1986-05-01 00:00:00

abstract：:During the long-term follow-up of patients with hypertrophic cardiomyopathy (HCM), some patients develop left ventricular (LV) wall motion abnormalities in the absence of fixed coronary artery disease. The purpose of this study is to clarify which clinical features in patients with HCM seem to influence gradual develo...

journal_title：European heart journal

authors： Ishiwata S,Nishiyama S,Nakanishi S,Seki A

更新日期：1993-12-01 00:00:00

abstract：:We studied the effects of a chronic increase in flow and of chronic hypertension on regional pulmonary blood volume and extravascular lung density (lung tissue and interstitial water per unit thoracic volume) in one group of patients with intracardiac, left-to-right shunt and in another group with Eisenmenger's syndro...

journal_title：European heart journal

authors： Wollmer P,Rozkovec A,Rhodes CG,Allan RM,Maseri A

更新日期：1984-11-01 00:00:00

abstract：AIMS:Angiographic studies on the natural course of both focal and diffuse coronary atherosclerosis have not been performed before, but can both be assessed by quantitative coronary angiography. The objective of this study was to describe the natural course of focal and diffuse coronary atherosclerosis over time. METHO...

journal_title：European heart journal

authors： Vos J,de Feyter PJ,Kingma JH,Emanuelsson H,Legrand V,Winkelmann B,Dumont JM,Simoons LM

更新日期：1997-07-01 00:00:00

abstract：AIMS:Subjects with lipoprotein(a) [Lp(a)] elevation have increased arterial wall inflammation and cardiovascular risk. In patients at increased cardiovascular risk, arterial wall inflammation is reduced following lipid-lowering therapy by statin treatment or lipoprotein apheresis. However, it is unknown whether lipid-l...

journal_title：European heart journal

authors： Stiekema LCA,Stroes ESG,Verweij SL,Kassahun H,Chen L,Wasserman SM,Sabatine MS,Mani V,Fayad ZA

更新日期：2019-09-01 00:00:00

abstract：:The non-invasive quantification of mitral and aortic regurgitation using the left-to-right stroke count ratio (SCR) calculated with gated equilibrium radionuclide ventriculography (RNV), is affected by the overlap of atria and ventricles and the consequent difficult definition of the ventricular regions of interest (R...

journal_title：European heart journal

authors： Sciagrà R,Voth E,Tebbe U,Schicha H,Neuhaus KL

更新日期：1987-10-01 00:00:00

abstract：AIMS:The aim of the study was to evaluate the long-term results of allograft and prosthetic valve replacement in the treatment of infective aortic valve endocarditis with periannular abscess. METHODS:Between March 1988 and March 1996, 65 patients underwent surgery for active aortic valve endocarditis and paravalvular ...

journal_title：European heart journal

authors： Knosalla C,Weng Y,Yankah AC,Siniawski H,Hofmeister J,Hammerschmidt R,Loebe M,Hetzer R

更新日期：2000-03-01 00:00:00

abstract：:The purpose of this prospective study was to examine the incidence of exercise-induced ischaemia before and after angioplasty as well as 4 months later by exercise echocardiography, to evaluate the prognostic value of exercise echocardiography performed after angioplasty as regards the development of restenosis and to...

journal_title：European heart journal

authors： Hoffmann R,Lethen H,Flachskampf FA,Hanrath P

更新日期：1995-12-01 00:00:00

abstract：AIMS:To document tracking patterns, if any, over time, of classical cardiovascular risk factors in men and women participants in the Vorarlberg Health Monitoring and Promotion Programme (VHM&PP) METHODS AND RESULTS: 67,413 men and 82,237 women underwent a total of 45,4448 standardised examinations in the 15 year period...

journal_title：European heart journal

authors： Ulmer H,Kelleher C,Diem G,Concin H

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to describe the frequencies of various diagnoses in patients admitted with acute chest pain, but without acute myocardial infarction, and to evaluate a non-invasive screening programme for these patients. PATIENTS:A total of 204 consecutive non-acute myocardial infarction patien...

journal_title：European heart journal

authors： Fruergaard P,Launbjerg J,Hesse B,Jørgensen F,Petri A,Eiken P,Aggestrup S,Elsborg L,Mellemgaard K

更新日期：1996-07-01 00:00:00

abstract：:Ambient air pollution is a leading cause of non-communicable disease globally. The largest proportion of deaths and morbidity due to air pollution is now known to be due to cardiovascular disorders. Several particulate and gaseous air pollutants can trigger acute events (e.g. myocardial infarction, stroke, heart failu...

journal_title：European heart journal

authors： Münzel T,Gori T,Al-Kindi S,Deanfield J,Lelieveld J,Daiber A,Rajagopalan S

更新日期：2018-10-07 00:00:00

abstract：:Three different bradycardic agents, alinidine, AQ-A39 and UL-FS49 increase the intrinsic cycle length of the isolated SA node preparation of the rabbit. This increase is mainly caused by a decrease in rate of diastolic depolarization. One of these agents, alinidine, was used to study the underlying ionic mechanism of ...

journal_title：European heart journal

authors： van Ginneken AC,Bouman LN,Jongsma HJ,Duivenvoorden JJ,Opthof T,Giles WR

更新日期：1987-12-01 00:00:00

abstract：:Antithrombotic therapy and invasive risk stratification in selected high-risk patients have improved outcomes from non-ST-segment elevation acute coronary syndromes (NSTE-ACS), but carry a risk of bleeding and blood transfusion. Although the true incidence of bleeding depends on the population studied (i.e. clinical t...

journal_title：European heart journal

authors： Rao SV,Eikelboom JA,Granger CB,Harrington RA,Califf RM,Bassand JP

更新日期：2007-05-01 00:00:00

abstract：AIMS:Effects of the bradycardic agent ivabradine on regional blood flow, contractile function, and infarct size were studied in a pig model of myocardial ischaemia/reperfusion. Heart rate reduction by beta-blockade is associated with negative inotropism and unmasked alpha-adrenergic coronary vasoconstriction. Ivabradin...

journal_title：European heart journal

authors： Heusch G,Skyschally A,Gres P,van Caster P,Schilawa D,Schulz R

更新日期：2008-09-01 00:00:00

abstract：:Increased levels of low density lipoprotein (LDL) cholesterol and triglyceride, and low levels of high density lipoprotein (HDL) cholesterol, are associated with increased risk of coronary heart disease (CHD). Only a minor part of the variation in lipids can be explained by defects in single genes of large effect; the...

journal_title：European heart journal

authors： Cullen P,Funke H,Schulte H,Assmann G

更新日期：1998-04-01 00:00:00

abstract：: ...

journal_title：European heart journal

authors： Libby P

更新日期：2019-03-14 00:00:00

abstract：AIMS:Growth differentiation factor 11 and/or its homologue growth differentiation factor 8 (GDF11/8) reverses age-related cardiac hypertrophy and vascular ageing in mice. We investigated whether GDF11/8 associates with cardiovascular outcomes, left ventricular hypertrophy (LVH), or age in humans. METHODS AND RESULTS:W...

journal_title：European heart journal

authors： Olson KA,Beatty AL,Heidecker B,Regan MC,Brody EN,Foreman T,Kato S,Mehler RE,Singer BS,Hveem K,Dalen H,Sterling DG,Lawn RM,Schiller NB,Williams SA,Whooley MA,Ganz P

更新日期：2015-12-21 00:00:00

abstract：AIMS:Despite advances in the treatment of acute coronary syndromes based on randomized trial data and published guidelines, the extent to which such treatments are applied in practice remains uncertain. Data from clinical trials derive from selected geographical areas and in highly selected populations of patients, and...

journal_title：European heart journal

authors： Fox KA,Goodman SG,Klein W,Brieger D,Steg PG,Dabbous O,Avezum A

更新日期：2002-08-01 00:00:00

abstract：:To evaluate gender-related differences in left ventricular (LV) structure and function in aortic stenosis, LV biplane cineangiography, micromanometry and endomyocardial biopsies were carried out in 56 patients with aortic stenosis and normal coronary arteries. Patients were divided into males (M: n = 35), and females ...

journal_title：European heart journal

authors： Villari B,Campbell SE,Schneider J,Vassalli G,Chiariello M,Hess OM

更新日期：1995-10-01 00:00:00

abstract：:Hypertension (HTN) is quantitatively the major cardiovascular risk factor and responsible for ∼50% of cardiovascular morbidity and mortality. Blood pressure (BP) is also a classical complex genetic trait with heritability estimates of 30-50%. Although much is known about BP regulation, the intrinsic origin of essentia...

journal_title：European heart journal

authors： Ehret GB,Caulfield MJ

更新日期：2013-04-01 00:00:00