Impact of glucose-lowering drugs on cardiovascular disease in type 2 diabetes.

abstract：:Nitrates are beneficial because they combine coronary and noncoronary effects. They have proven clinical efficacy, relieving symptoms and documented evidence of ischaemia. They can be given to patients by multiple routes and can be easily combined with other anti-ischaemic drugs including aspirin, heparin, calcium ant...

journal_title：European heart journal

authors： Conti CR

更新日期：1991-05-01 00:00:00

abstract：:Large-scale randomized clinical trials have established the efficacy of cholesterol-lowering, blood pressure-lowering, and anti-platelet therapy to prevent cardiovascular diseases. A challenge for clinicians is to apply group-level evidence from these trials to individual patients. Trials typically report a single tre...

journal_title：European heart journal

authors： van der Leeuw J,Ridker PM,van der Graaf Y,Visseren FL

更新日期：2014-04-01 00:00:00

abstract：:We now have conclusive data that ACE inhibitors reduce mortality, morbidity, and symptoms in patients with low ejection fraction and/or heart failure. Therefore, ACE inhibitors should be routinely used in all such patients, as long as there are no clear contraindications. Routine use of ACE inhibitors will lead to pro...

journal_title：European heart journal

authors： McKelvie R,McConachie D,Yusuf S

更新日期：1994-05-01 00:00:00

abstract：AIMS:To assess the prognostic significance of infarct core tissue characteristics using cardiac magnetic resonance (CMR) imaging in survivors of acute ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS:We performed an observational prospective single centre cohort study in 300 reperfused STEMI patients (m...

journal_title：European heart journal

authors： Carrick D,Haig C,Rauhalammi S,Ahmed N,Mordi I,McEntegart M,Petrie MC,Eteiba H,Hood S,Watkins S,Lindsay M,Mahrous A,Ford I,Tzemos N,Sattar N,Welsh P,Radjenovic A,Oldroyd KG,Berry C

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:In patients with postinfarction sustained ventricular tachycardia showing one or more antiarrhythmic drug failures, the question is how long to proceed with new drug trials before deciding to perform map-guided arrhythmia surgery. Although the techniques of this surgery developed rapidly in the early 1980s, ...

journal_title：European heart journal

authors： van Hemel NM,Kingma JH,Defauw JJ,Hoogteijling-van Dusseldorp E,Kelder JC,Beukema WP,Vermeulen FE

更新日期：1996-04-01 00:00:00

abstract：:To study the haemodynamic and neurohumoral effects of nisoldipine (2 X 10 mg) vs captopril (3 X 25 mg), 24 patients with heart failure (New York Heart Association class II and III) due to coronary artery disease were treated in a randomized double-blind trial over 3 months. Both drugs were well tolerated. Clinical sta...

journal_title：European heart journal

authors： Schofer J,Hobuss M,Aschenberg W,Tews A

更新日期：1990-08-01 00:00:00

abstract：AIMS:The population with stable coronary artery disease (SCAD) is growing but validated models to guide their clinical management are lacking. We developed and validated prognostic models for all-cause mortality and non-fatal myocardial infarction (MI) or coronary death in SCAD. METHODS AND RESULTS:Models were develop...

journal_title：European heart journal

authors： Rapsomaniki E,Shah A,Perel P,Denaxas S,George J,Nicholas O,Udumyan R,Feder GS,Hingorani AD,Timmis A,Smeeth L,Hemingway H

更新日期：2014-04-01 00:00:00

abstract：:Despite therapeutic improvements, cardiogenic shock (CS) remains the most common cause of death in patients with acute myocardial infarction (AMI). In addition to percutaneous coronary intervention, inotropes, fluids, adjunctive medication, intra-aortic balloon counterpulsation, and also assist devices are widely used...

journal_title：European heart journal

authors： Thiele H,Allam B,Chatellier G,Schuler G,Lafont A

更新日期：2010-08-01 00:00:00

abstract：AIM:To evaluate the effect of alirocumab on frequency of standard apheresis treatments [weekly or every 2 weeks (Q2W)] in heterozygous familial hypercholesterolaemia (HeFH). METHODS AND RESULTS:ODYSSEY ESCAPE (NCT02326220) was a double-blind study in 62 HeFH patients undergoing regular weekly or Q2W lipoprotein aphere...

journal_title：European heart journal

authors： Moriarty PM,Parhofer KG,Babirak SP,Cornier MA,Duell PB,Hohenstein B,Leebmann J,Ramlow W,Schettler V,Simha V,Steinhagen-Thiessen E,Thompson PD,Vogt A,von Stritzky B,Du Y,Manvelian G

更新日期：2016-12-21 00:00:00

abstract：:Priorities for unanswered questions concerning major areas of cardiovascular disease are being sought by the British Cardiovascular Society, using the methods of the James Lind Alliance, which involves clinicians and patients in an equal partnership, reports Barry Shurlock PhD. ...

journal_title：European heart journal

authors：

更新日期：2015-06-01 00:00:00

abstract：Aims:Atrial fibrillation (AFib) and atrial flutter (AFlut) are common arrhythmias with increased use of invasive procedures. A steady re-evaluation of relevant safety endpoints is recommended and both quality management and pay-for-performance programs are evolving. Therefore, the aims of this study were (i) to investi...

journal_title：European heart journal

authors： König S,Ueberham L,Schuler E,Wiedemann M,Reithmann C,Seyfarth M,Sause A,Tebbenjohanns J,Schade A,Shin DI,Staudt A,Zacharzowsky U,Andrié R,Wetzel U,Neuser H,Wunderlich C,Kuhlen R,Tijssen JGP,Hindricks G,Bollmann A

更新日期：2018-11-21 00:00:00

abstract：:Sequential alterations of left ventricular volumes and haemodynamics were studied in 29 patients between 4 days and 4 weeks after myocardial infarction. Left ventricular volume was determined by single photon emission computerized tomography (SPECT), infarct size by creatine kinase (CK) analysis, angiography and thall...

journal_title：European heart journal

authors： Gaudron P,Eilles C,Ertl G,Kochsiek K

更新日期：1990-04-01 00:00:00

abstract：:Contrary to most prospective epidemiologic studies, an earlier report from the British Regional Heart Study (BRHS) suggested that high density lipoprotein (HDL)-cholesterol in men aged 40-59 years was not a significant, independent, predictive risk factor for coronary heart disease (CHD), controlling for the composite...

journal_title：European heart journal

authors： Tyroler HA

更新日期：1990-12-01 00:00:00

abstract：:The mechanism of coronary spasm is poorly understood. We report a case of coronary artery spasm in a cardiac transplant patient. Pharmacologic testing indicated denervation of the patient's heart. Therefore coronary artery spasm may occur despite cardiac denervation. This case demonstrates that intact autonomic nervou...

journal_title：European heart journal

authors： Cattan S,Drobinski G,Artigou JY,Grogogeat Y,Cabrol C

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:Anti-ischaemic therapy with nitrates and/or calcium channel blockers profoundly affects the results of pharmacological stress echocardiography with coronary vasodilators but the influence on catecholamine stress testing remains unsettled. AIMS:The present study aimed to assess the effects of non-beta-blocke...

journal_title：European heart journal

authors： Dodi C,Pingitore A,Sicari R,Bruno G,Cordovil A,Picano E

更新日期：1997-02-01 00:00:00

abstract：:Reverse cholesterol transport is a multi-step process resulting in the net movement of cholesterol from peripheral tissues back to the liver via the plasma compartment. Cellular cholesterol efflux is mediated by HDL, acting in conjunction with the cholesterol esterifying enzyme, lecithin: cholesterol acyltransferase. ...

journal_title：European heart journal

authors： Tall AR

更新日期：1998-02-01 00:00:00

abstract：AIMS:We designed this study in order to determine the effect of insulin on cardiac function in overweight and obese subjects during exercise. METHODS AND RESULTS:The cardiac function of 62 normal glucose tolerant subjects, aged 30-40 and divided into normal weight (group 1, n=22, BMI 20-24.9 kg/m(2)), overweight (grou...

journal_title：European heart journal

authors： Sasso FC,Carbonara O,Nasti R,Marfella R,Esposito K,Rambaldi P,Mansi L,Salvatore T,Torella R,Cozzolino D

更新日期：2005-06-01 00:00:00

abstract：:The utility of high-frequency current applied through the distal electrode of a conventional electrode-catheter for altering atrio-ventricular conduction was studied in 18 anaesthetized dogs. Following adequate unipolar His bundle recording, current was applied over periods of 20-30 s, with an output power of 30 W. Co...

journal_title：European heart journal

authors： Lopez-Merino V,Chorro FJ,Sanchis J,Garcia-Civera R,Such L,Camañas A,Paya R

更新日期：1989-02-01 00:00:00

abstract：AIMS:Despite advances in the treatment of acute coronary syndromes based on randomized trial data and published guidelines, the extent to which such treatments are applied in practice remains uncertain. Data from clinical trials derive from selected geographical areas and in highly selected populations of patients, and...

journal_title：European heart journal

authors： Fox KA,Goodman SG,Klein W,Brieger D,Steg PG,Dabbous O,Avezum A

更新日期：2002-08-01 00:00:00

abstract：AIMS:The guidelines of the European Society of Cardiology (ESC) define the current standard for the management of syncope, but are still incompletely applied in the clinical setting. METHODS AND RESULTS:Prospective systematic evaluation, on strict adherence to the guidelines, of consecutive patients referred for synco...

journal_title：European heart journal

authors： Brignole M,Menozzi C,Bartoletti A,Giada F,Lagi A,Ungar A,Ponassi I,Mussi C,Maggi R,Re G,Furlan R,Rovelli G,Ponzi P,Scivales A

更新日期：2006-01-01 00:00:00

abstract：:Eight young healthy male subjects, members of a Himalayan expedition, underwent 24 h Holter monitoring before departure, after 1 and 4 weeks at high altitude (5000 m) and after return to sea level. At high altitude, the circadian reciprocal changes in low and high frequency (LF, HF) were absent, with no significant re...

journal_title：European heart journal

authors： Ponchia A,Noventa D,Bertaglia M,Carretta R,Zaccaria M,Miraglia G,Pascotto P,Buja G

更新日期：1994-11-01 00:00:00

abstract：AIMS:Diastolic dysfunction in acute myocardial infarction (MI) is associated with adverse outcome. Recently, the ratio of early mitral inflow velocity (E) to global diastolic strain rate (e'sr) has been proposed as a marker of elevated LV filling pressure. However, the prognostic value of this measure has not been demo...

journal_title：European heart journal

authors： Ersbøll M,Andersen MJ,Valeur N,Mogensen UM,Fakhri Y,Thune JJ,Møller JE,Hassager C,Søgaard P,Køber L

更新日期：2014-03-01 00:00:00

abstract：:The aim of this study was to improve the reproducibility and the standardization of the topographical assessment of myocardial infarctions in routine two-dimensional echocardiography. A myocardial map of the left ventricle was derived from a necropsy study of normal human hearts; interventricular grooves and papillary...

journal_title：European heart journal

authors： Touche T,Vervin P,Prasquier R,Diebold B,Curien N,Gourgon R

更新日期：1983-11-01 00:00:00

abstract：:In this study, two patterns of regional contract on of the left ventricle have been studied: endocardial motion and wall thickening, in order to check which of these was the most affected after myocardial infarction. The clinical relevance of this comparison was to assess which parameter of the regional contraction ab...

journal_title：European heart journal

authors： Germain P,Roul G,Constantinesco A,Coulbois PM,Baruthio J,Mossard JM,Bareiss P,Sacrez A

更新日期：1996-09-01 00:00:00

abstract：:Modern-day stenting procedures leverage advances in pharmacotherapy and device innovation. Patients treated with contemporary antiplatelet agents, peri-procedural antithrombin therapy and new-generation drug-eluting stents (DES) have excellent outcomes over the short to medium term. Indeed, coupled with the reducing c...

journal_title：European heart journal

authors： Byrne RA,Joner M,Kastrati A

更新日期：2015-12-14 00:00:00

abstract：AIMS:To compare two different clopidogrel regimens on the outcomes of patients undergoing elective coronary angiography (CAG)+/-ad hoc percutaneous coronary intervention (PCI). METHODS AND RESULTS:Open-trial randomized 1028 patients with stable angina to group A ('non-selective'-clopidogrel 600 mg > 6 h before CAG; n ...

journal_title：European heart journal

authors： Widimsky P,Motovská Z,Simek S,Kala P,Pudil R,Holm F,Petr R,Bílková D,Skalická H,Kuchynka P,Poloczek M,Miklík R,Maly M,Aschermann M,PRAGUE-8 Trial Investigators.

更新日期：2008-06-01 00:00:00

abstract：:The acute electrophysiologic effects of clinical doses of procainamide, lidocaine, metoprolol, digoxin and atropine upon the conduction of ventricular premature beats, were studied in 48 healthy volunteers. The conduction time of the first premature beat, induced 1 ms after the ventricular effective refractory period ...

journal_title：European heart journal

authors： Edvardsson N,Hirsch I,Olsson SB

更新日期：1985-01-01 00:00:00

abstract：:In 70 patients, tricuspid regurgitation was diagnosed with Doppler by recording reverse flow in systole originating at the tricuspid orifice, directed into the right atrium. The peak velocities were recorded, and the peak pressure drop from the right ventricle to the right atrium in systole was calculated from the sim...

journal_title：European heart journal

authors： Skjaerpe T,Hatle L

更新日期：1986-08-01 00:00:00

abstract：:Antithrombotic therapy and invasive risk stratification in selected high-risk patients have improved outcomes from non-ST-segment elevation acute coronary syndromes (NSTE-ACS), but carry a risk of bleeding and blood transfusion. Although the true incidence of bleeding depends on the population studied (i.e. clinical t...

journal_title：European heart journal

authors： Rao SV,Eikelboom JA,Granger CB,Harrington RA,Califf RM,Bassand JP

更新日期：2007-05-01 00:00:00

abstract：AIMS:A small reference diameter may be the consequence of high plaque burden and diffuse disease. The reference vessel diameter in small coronary arteries may vary according to the method of measurement used. We endeavoured to confirm the difference between data from examinations conducted using angiography with that r...

journal_title：European heart journal

authors： Briguori C,Tobis J,Nishida T,Vaghetti M,Albiero R,Di Mario C,Colombo A

更新日期：2002-02-01 00:00:00