Red alert for women's heart: the urgent need for more research and knowledge on cardiovascular disease in women: proceedings of the workshop held in Brussels on gender differences in cardiovascular disease, 29 September 2010.

Abstract:

:A recent report of the EuroHeart project has shown that women are still underrepresented in many cardiovascular clinical trials, while important gender differences are present within most areas of heart disease. As the burden of cardiovascular disease is increasing in middle-aged women relative to men, a more profound understanding is needed of the fundamental biological differences that exist between men and women. In the current review, we aim to address the need for more explanatory sex-specific cardiovascular research to be able to adapt existing guidelines for a better heart health in women.

journal_name

Eur Heart J

journal_title

European heart journal

authors

Maas AH,van der Schouw YT,Regitz-Zagrosek V,Swahn E,Appelman YE,Pasterkamp G,Ten Cate H,Nilsson PM,Huisman MV,Stam HC,Eizema K,Stramba-Badiale M

doi

10.1093/eurheartj/ehr048

subject

Has Abstract

pub_date

2011-06-01 00:00:00

pages

1362-8

issue

11

eissn

0195-668X

issn

1522-9645

pii

ehr048

journal_volume

32

pub_type

杂志文章,评审
  • Lack of influence of propranolol and metoprolol on walking distance in patients with chronic intermittent claudication.

    abstract::Ten patients with chronic intermittent claudication were included in a double-blind, randomized cross-over study of placebo, propranolol 80 mg b.i.d. and metoprolol 100 mg b.i.d., each given for two months. At the end of each treatment period, the patients were tested on a treadmill and the time to first claudication ...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/oxfordjournals.eurheartj.a061440

    authors: Bogaert MG,Clement DL

    更新日期:1983-03-01 00:00:00

  • Combined non-invasive functional and anatomical diagnostic work-up in clinical practice: the magnetic resonance and computed tomography in suspected coronary artery disease (MARCC) study.

    abstract:AIMS:The combined use of cardiac computed tomography (CT) coronary angiography (CTCA) and myocardial perfusion imaging allows the non-invasive evaluation of coronary morphology and function. Cardiovascular magnetic resonance (CMR) imaging has several advantages: it can simultaneously assess myocardial perfusion, ventri...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/eht077

    authors: Groothuis JG,Beek AM,Brinckman SL,Meijerink MR,van den Oever ML,Hofman MB,van Kuijk C,van Rossum AC

    更新日期:2013-07-01 00:00:00

  • Is a systolic blood pressure target

    abstract:AIMS:Major guidelines recommend lowering systolic blood pressure (SBP) to <140 mmHg in all hypertensives, but evidence is missing whether this is beneficial in (i) uncomplicated hypertensives, (ii) grade 1 hypertensives, and (iii) elderly hypertensives. Providing this missing evidence is important to justify efforts an...

    journal_title:European heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/eurheartj/ehr039

    authors: Zhang Y,Zhang X,Liu L,Zanchetti A,FEVER Study Group.

    更新日期:2011-06-01 00:00:00

  • Blood pressure, heart rate, and mortality in chronic obstructive pulmonary disease: the SUMMIT trial.

    abstract:Aims:To characterize the relationship between blood pressure (BP) or heart rate and mortality and morbidity in chronic obstructive pulmonary disease (COPD). Methods and results:We performed post hoc analysis of baseline BP or heart rate and all-cause mortality and cardiovascular events in the SUMMIT trial. SUMMIT was ...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/ehy451

    authors: Byrd JB,Newby DE,Anderson JA,Calverley PMA,Celli BR,Cowans NJ,Crim C,Martinez FJ,Vestbo J,Yates J,Brook RD,SUMMIT Investigators.

    更新日期:2018-09-01 00:00:00

  • Comparison of coronary bypass surgery with drug-eluting stenting for the treatment of left main and/or three-vessel disease: 3-year follow-up of the SYNTAX trial.

    abstract:AIMS:Long-term randomized comparisons of percutaneous coronary intervention (PCI) to coronary artery bypass grafting (CABG) in left main coronary (LM) disease and/or three-vessel disease (3VD) patients have been limited. This analysis compares 3-year outcomes in LM and/or 3VD patients treated with CABG or PCI with TAXU...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/ehr213

    authors: Kappetein AP,Feldman TE,Mack MJ,Morice MC,Holmes DR,Ståhle E,Dawkins KD,Mohr FW,Serruys PW,Colombo A

    更新日期:2011-09-01 00:00:00

  • Development and validation of a prognostic risk score for major bleeding in patients undergoing percutaneous coronary intervention via the femoral approach.

    abstract:AIMS:Major bleeding after percutaneous coronary intervention (PCI) is an independent risk factor for early and late mortality. We developed and validated a risk score predictive of major bleeding after PCI using the femoral approach. METHODS AND RESULTS:Baseline clinical and procedural variables from two contemporary,...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/ehm194

    authors: Nikolsky E,Mehran R,Dangas G,Fahy M,Na Y,Pocock SJ,Lincoff AM,Stone GW

    更新日期:2007-08-01 00:00:00

  • Successful treatment of acute myocardial ischaemia with teopranitol--a novel organic nitrate.

    abstract::The present study was designed to examine the effects of a new organic nitrate, teopranitol, in acute myocardial ischaemia. Adult cats were subjected to 5 h of myocardial ischaemia by permanent ligation of the left anterior descending coronary artery (LAD). Teopranitol (10 mg kg-1 X h) or physiological saline (vehicle...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a062083

    authors: Thiemermann C,Smith EF 3rd,Schrör K

    更新日期:1986-05-01 00:00:00

  • Comparative study of echo- and angiocardiographically determined regional left ventricular wall motion in recent myocardial infarction.

    abstract::We have studied regional left ventricular (LV) wall motion with M-mode, cross-sectional (2D) echocardiography and LV angiography in 50 patients with a recent myocardial infarction. Regional LV wall motion was evaluated according to a 9-segment model. 2D echocardiography permitted information from all, M-mode echocardi...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a061703

    authors: Lindvall K,Hamsten A,Landou C,Szamosi A,de Faire U

    更新日期:1984-07-01 00:00:00

  • Repolarization abnormalities with prolonged hyperventilation in apparently healthy subjects: incidence, mechanisms and affecting factors.

    abstract::Brief hyperventilation is occasionally accompanied by repolarization abnormalities in subjects without apparent heart disease. However, the effect of prolonged hyperventilation on repolarization abnormalities is not clearly defined. We analysed the repolarization abnormalities induced by prolonged hyperventilation, co...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a015079

    authors: Alexopoulos D,Christodoulou J,Toulgaridis T,Sitafidis G,Manias O,Hahalis G,Vagenakis AG

    更新日期:1996-09-01 00:00:00

  • Association of low ankle brachial index with high mortality in primary care.

    abstract:AIMS:We aimed to assess the increased risk of death and severe vascular events in elderly individuals with subclinical or manifest peripheral arterial disease (PAD), evidenced by low ankle brachial index (ABI < 0.9) in primary care. METHODS AND RESULTS:In this monitored prospective observational study, 6880 representa...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehl092

    authors: Diehm C,Lange S,Darius H,Pittrow D,von Stritzky B,Tepohl G,Haberl RL,Allenberg JR,Dasch B,Trampisch HJ

    更新日期:2006-07-01 00:00:00

  • Auto-titrating continuous positive airway pressure therapy in patients with chronic heart failure and obstructive sleep apnoea: a randomized placebo-controlled trial.

    abstract:AIMS:Obstructive sleep apnoea (OSA) is highly prevalent in patients with chronic heart failure (CHF) and may contribute to CHF progression. We aimed to determine whether treatment of OSA with continuous positive airway pressure (CPAP) would improve subjective and objective measures of heart failure severity in patients...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/ehm131

    authors: Smith LA,Vennelle M,Gardner RS,McDonagh TA,Denvir MA,Douglas NJ,Newby DE

    更新日期:2007-05-01 00:00:00

  • Long-term prognosis of patients with paroxysmal atrial fibrillation complicating acute myocardial infarction. SPRINT Study Group.

    abstract::The aim of the study was to assess the relationship between paroxysmal atrial fibrillation during acute myocardial infarction and the long-term prognosis of patients after acute myocardial infarction. The incidence of paroxysmal atrial fibrillation among 5803 consecutive hospitalized patients was 9.9% (557/5803). Inci...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a060046

    authors: Behar S,Zahavi Z,Goldbourt U,Reicher-Reiss H

    更新日期:1992-01-01 00:00:00

  • Cardiovascular effects of flavanol-rich chocolate in patients with heart failure.

    abstract:AIMS:Flavanol-rich chocolate (FRC) is beneficial for vascular and platelet function by increasing nitric oxide bioavailability and decreasing oxidative stress. Congestive heart failure (CHF) is characterized by impaired endothelial and increased platelet reactivity. As statins are ineffective in CHF, alternative therap...

    journal_title:European heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/eurheartj/ehr448

    authors: Flammer AJ,Sudano I,Wolfrum M,Thomas R,Enseleit F,Périat D,Kaiser P,Hirt A,Hermann M,Serafini M,Lévêques A,Lüscher TF,Ruschitzka F,Noll G,Corti R

    更新日期:2012-09-01 00:00:00

  • Intravenous acebutolol raises serum potassium in acute myocardial infarction.

    abstract::Hypokalaemia commonly occurs in acute myocardial infarction (AMI) and may be caused by elevated serum levels of adrenaline, allegedly by beta 2-adrenergic mediated influx of potassium (K) into cells. We investigated the effect on serum K of intravenous acebutolol (a relatively beta 1-selective agent) in 50 patients wi...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a062036

    authors: Jardine RM,Obel IW,Smith AM

    更新日期:1986-02-01 00:00:00

  • Beneficial effect of residual anterograde flow on tissue viability as assessed by positron emission tomography in patients with myocardial infarction.

    abstract::With the advent of therapeutic interventions to restore blood flow in patients with acute infarction, early identification of salvageable myocardium has gained clinical importance. It was the purpose of this study to define regional blood flow and glucose metabolism in patients with acute myocardial infarction as asse...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a062375

    authors: Schwaiger M,Brunken RC,Krivokapich J,Child JS,Tillisch JH,Phelps ME,Schelbert HR

    更新日期:1987-09-01 00:00:00

  • Cabins, castles, and constant hearts: rhythm control therapy in patients with atrial fibrillation.

    abstract::Recent innovations have the potential to improve rhythm control therapy in patients with atrial fibrillation (AF). Controlled trials provide new evidence on the effectiveness and safety of rhythm control therapy, particularly in patients with AF and heart failure. This review summarizes evidence supporting the use of ...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/ehz782

    authors: Willems S,Meyer C,de Bono J,Brandes A,Eckardt L,Elvan A,van Gelder I,Goette A,Gulizia M,Haegeli L,Heidbuchel H,Haeusler KG,Kautzner J,Mont L,Ng GA,Szumowski L,Themistoclakis S,Wegscheider K,Kirchhof P

    更新日期:2019-12-07 00:00:00

  • Cardio-Oncology Services: rationale, organization, and implementation.

    abstract:AIMS:Anticancer therapies have extended the lives of millions of patients with malignancies, but for some this benefit is tempered by adverse cardiovascular (CV) effects. Cardiotoxicity may occur early or late after treatment initiation or termination. The extent of this cardiotoxicity is variable, depending on the typ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehy453

    authors: Lancellotti P,Suter TM,López-Fernández T,Galderisi M,Lyon AR,Van der Meer P,Cohen Solal A,Zamorano JL,Jerusalem G,Moonen M,Aboyans V,Bax JJ,Asteggiano R

    更新日期:2019-06-07 00:00:00

  • A comparison between coronary artery bypass grafting surgery and drug eluting stent for the treatment of unprotected left main coronary artery disease in elderly patients (aged > or =75 years).

    abstract:AIMS:In this study, we compared the clinical outcomes of elderly patients with unprotected left main coronary artery (ULMCA) stenosis treated with either coronary artery bypass grafting (CABG) or drug-eluting stent (DES). METHODS AND RESULTS:From January 2003 to April 2006, 259 patients with ULMCA stenosis and age > o...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehm403

    authors: Palmerini T,Barlocco F,Santarelli A,Bacchi-Reggiani L,Savini C,Baldini E,Alessi L,Ruffini M,Di Credico G,Piovaccari G,Di Bartolomeo R,Marzocchi A,Branzi A,De Servi S

    更新日期:2007-11-01 00:00:00

  • Endothelium-derived nitric oxide: the endogenous nitrovasodilator in the human cardiovascular system.

    abstract::The L-arginine pathway within endothelial cells in the blood vessel wall is the source of production of the endogenous nitrovasodilator, nitric oxide (NO). NO is released under basal conditions and in response to various stimuli such as shear stress and in response to platelet-derived products, coagulation factors and...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/12.suppl_e.2

    authors: Lüscher TF

    更新日期:1991-11-01 00:00:00

  • Variable response to atrial pacing after intravenous propranolol in patients with stable exertional angina.

    abstract::The effect of propranolol administration on regional coronary haemodynamics were investigated in 14 patients with stable exertional angina and isolated left anterior descending artery disease. Thermodilution was used to measure great cardiac vein flow (GCVF) and anterior regional coronary resistance (ARCR) under contr...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a059640

    authors: De Servi S,Ferrario M,Ghio S,Cioffi P,Angoli L,Bramucci E,Aimè E,Montericcio V,Specchia G

    更新日期:1990-11-01 00:00:00

  • Primary prevention implantable cardioverter-defibrillator and opportunities for sudden cardiac death risk assessment in non-ischaemic cardiomyopathy.

    abstract::Sudden cardiac death (SCD) accounts for approximately one-third of all deaths among patients with non-ischaemic cardiomyopathy (NICM). Implantable cardioverter-defibrillator (ICD) therapy has been the primary intervention for managing individuals at high risk for SCD. However, individual ICD trials in the NICM populat...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/ehy344

    authors: Pathak RK,Sanders P,Deo R

    更新日期:2018-08-14 00:00:00

  • Effects of transdermal nitroglycerin in combination with an ACE inhibitor in patients with chronic stable angina pectoris.

    abstract::We have previously shown that transdermal nitroglycerin may induce an increase in the activity of the adrenergic and the renin-angiotensin-aldosterone systems (SRAA) in patients with chronic stable angina pectoris (SA); when the activation of these systems is more pronounced, the antianginal effect of this drug seems ...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/14.12.1701

    authors: Muiesan ML,Boni E,Castellano M,Beschi M,Cefis G,Cerri B,Verdecchia P,Porcellati C,Pollavini G,Agabiti-Rosei E

    更新日期:1993-12-01 00:00:00

  • Plasma concentrations of platelet-specific proteins in young female acute myocardial infarction survivors and their age-matched female controls.

    abstract::The steady state plasma concentrations of the two platelet-specific proteins beta-thromboglobulin (BTG) and platelet factor 4 (PF4) were determined in two groups of females: 36 acute myocardial infarction (AMI) survivors, and 38 age-matched control subjects. For the AMI patients the mean BTG and PF4 values were 57 +/-...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a061465

    authors: Kutti J,Johansson S,Eriksson KA,Sigvaldason A,Vedin A,Wadenvik H,Wilhelmsson C

    更新日期:1983-05-01 00:00:00

  • Alinidine as a model of the mode of action of specific bradycardic agents on SA node activity.

    abstract::Three different bradycardic agents, alinidine, AQ-A39 and UL-FS49 increase the intrinsic cycle length of the isolated SA node preparation of the rabbit. This increase is mainly caused by a decrease in rate of diastolic depolarization. One of these agents, alinidine, was used to study the underlying ionic mechanism of ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/8.suppl_l.25

    authors: van Ginneken AC,Bouman LN,Jongsma HJ,Duivenvoorden JJ,Opthof T,Giles WR

    更新日期:1987-12-01 00:00:00

  • Mitral valve repair for mitral insufficiency.

    abstract::Degenerative mitral valve disease has become the major cause of mitral regurgitation in North America; it is incumbent on surgeons to know repair techniques and to document their results. Fortunately, improvements in myocardial protection have been concurrent with the evolution of mitral valve repair in our country. T...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/12.suppl_b.30

    authors: Loop FD,Cosgrove DM,Stewart WJ

    更新日期:1991-07-01 00:00:00

  • Management of the patient with left ventricular hypertrophy.

    abstract::The management of left ventricular hypertrophy (LVH) presupposes that the patient is identified by echocardiography and is carefully evaluated for risk stratification, taking into consideration possible associated complications. The role of non-pharmacological treatment is limited, except in obese patients. Drug treat...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/14.suppl_d.22

    authors: de Divitiis O,Celentano A,De Simone G,Di Somma S,Galderisi M,Liguori V,de Divitiis M,Petitto M

    更新日期:1993-07-01 00:00:00

  • Early revascularization is associated with improved survival in elderly patients with acute myocardial infarction complicated by cardiogenic shock: a report from the SHOCK Trial Registry.

    abstract:AIMS:The SHould we emergently revascularize Occluded Coronaries in cardiogenic shocK (SHOCK) Trial showed no benefit of early revascularization in patients aged >/=75 years with acute myocardial infarction and cardiogenic shock. We examined the effect of age on treatment and outcomes of patients with cardiogenic shock ...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0195-668x(02)00844-8

    authors: Dzavik V,Sleeper LA,Cocke TP,Moscucci M,Saucedo J,Hosat S,Jiang X,Slater J,LeJemtel T,Hochman JS,SHOCK Investigators.

    更新日期:2003-05-01 00:00:00

  • An international perspective on heart failure and left ventricular systolic dysfunction complicating myocardial infarction: the VALIANT registry.

    abstract:AIMS:We analysed the contemporary incidence, outcomes, and predictors of heart failure (HF) and/or left ventricular systolic dysfunction (LVSD) before discharge in patients with acute myocardial infarction (MI). The baseline presence of HF or LVSD, or its development during hospitalisation, increases short- and long-te...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ehj.2004.08.006

    authors: Velazquez EJ,Francis GS,Armstrong PW,Aylward PE,Diaz R,O'Connor CM,White HD,Henis M,Rittenhouse LM,Kilaru R,van Gilst W,Ertl G,Maggioni AP,Spac J,Weaver WD,Rouleau JL,McMurray JJ,Pfeffer MA,Califf RM,VALIANT registr

    更新日期:2004-11-01 00:00:00

  • Prospective cohort study of C-reactive protein as a predictor of clinical events in adults with congenital heart disease: results of the Boston adult congenital heart disease biobank.

    abstract:Aims:Despite the well-defined association of high-sensitivity hsCRP with cardiovascular outcomes in apparently healthy adults and those with acquired heart disease, the relevance of this inflammatory marker in adults with congenital heart disease (ACHD) remains unclear. We aimed to examine the clinical correlates and p...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehy362

    authors: Opotowsky AR,Valente AM,Alshawabkeh L,Cheng S,Bradley A,Rimm EB,Landzberg MJ

    更新日期:2018-09-07 00:00:00

  • Pathogenetic mechanisms and epidemiology of Chlamydia pneumoniae.

    abstract::The antibody prevalence data indicate that C. pneumoniae infections are common worldwide and more frequently occur in middle-aged and elderly males than in females. C. pneumoniae infections are first acquired in childhood in heavily populated areas, whereas in northern countries, first infections are generally at teen...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:

    authors: Leinonen M

    更新日期:1993-12-01 00:00:00