Effect of irbesartan and enalapril in non-ST elevation acute coronary syndrome: results of the randomized, double-blind ARCHIPELAGO study.

abstract：:Electrophysiological properties were studied in a heterotopic heart transplant model developed in 44 dogs (Group I). Cycle length was 359.5 +/- 55.2 ms in the recipient heart and 500.9 +/- 77.9 ms in the donor heart (P less than 0.001). Sinoatrial conduction time was 38.6 +/- 13.6 ms in the recipient heart and 38.6 +/...

journal_title：European heart journal

authors： Alvarez L,Escudero C,Alzueta J,Silva L,Márquez-Montes J,Castillo-Olivares JL

更新日期：1990-06-01 00:00:00

abstract：:Guidelines for the management of cardiovascular disease (CVD) stress the importance of treating global risk, rather than individual risk, factors. Patients at high cardiovascular (CV) risk, for example, benefit from a combination of aspirin, antihypertensive agents, lipid-lowering drugs, and possibly folic acid. As th...

journal_title：European heart journal

authors： Sleight P,Pouleur H,Zannad F

更新日期：2006-07-01 00:00:00

abstract：AIMS:Left ventricular (LV) hypertrophy and abnormal non-invasive measures of LV diastolic function are common in patients with severe aortic stenosis (AS) but their prognostic importance is uncertain. This study aimed to determine whether tissue Doppler measures of LV systolic and/or diastolic function or echocardiogra...

journal_title：European heart journal

authors： Stewart RA,Kerr AJ,Whalley GA,Legget ME,Zeng I,Williams MJ,Lainchbury J,Hamer A,Doughty R,Richards MA,White HD,New Zealand Heart Valve Study Investigators.

更新日期：2010-09-01 00:00:00

abstract：AIMS:Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a key regulator of extracellular matrix degradation. We examined relations of plasma total TIMP-1 to cardiovascular risk factors and echocardiographic left ventricular (LV) structure and function in a community-based sample. METHODS AND RESULTS:We studied 1069 ...

journal_title：European heart journal

authors： Sundström J,Evans JC,Benjamin EJ,Levy D,Larson MG,Sawyer DB,Siwik DA,Colucci WS,Wilson PW,Vasan RS

更新日期：2004-09-01 00:00:00

abstract：:Increased sympathetic tone is found in about 30% of patients with hypertension. This abnormality is closely associated with the metabolic syndrome of dyslipidaemia and hyperinsulinaemia. In this short review we discuss the mechanisms by which sympathetic over-activity could cause the metabolic syndrome. Sympathetic st...

journal_title：European heart journal

authors： Julius S

更新日期：1998-06-01 00:00:00

abstract：Aims:Pulmonary hypertension (PH) and pulmonary vascular disease (PVD) are common and associated with adverse outcomes in heart failure with preserved ejection fraction (HFpEF). Little is known about the impact of PVD on the pathophysiology of exercise intolerance. Methods and results:Heart failure with preserved eject...

journal_title：European heart journal

authors： Gorter TM,Obokata M,Reddy YNV,Melenovsky V,Borlaug BA

更新日期：2018-08-07 00:00:00

abstract：AIMS:LV reverse remodelling has been shown to be a favourable response after cardiac resynchronization therapy (CRT) in many clinical trials. This study investigated whether left ventricular (LV) reverse remodelling after CRT has any structural benefit, which include the improvement of LV mass or regional wall thicknes...

journal_title：European heart journal

authors： Zhang Q,Fung JW,Auricchio A,Chan JY,Kum LC,Wu LW,Yu CM

更新日期：2006-06-01 00:00:00

abstract：:Impaired relaxation of the ventricle has been described in hypertrophy and in ischemic heart disease. Some of these abnormalities are transient, but all occur at an early stage of the disease. The underlying mechanisms may vary depending on the etiology of the disease, and, except for ischemic heart disease, true myoc...

journal_title：European heart journal

authors： Brutsaert DL

更新日期：1983-01-01 00:00:00

abstract：AIMS:Periconceptional folate supplementation prevents neural tube defects and possibly congenital heart defects (CHD) as well. The search for candidate genes involved in the folate metabolism includes the methylenetetrahydrofolate reductase (MTHFR) 677C > T polymorphism. We studied the association between MTHFR 677C > ...

journal_title：European heart journal

authors： van Beynum IM,Kapusta L,den Heijer M,Vermeulen SH,Kouwenberg M,Daniëls O,Blom HJ

更新日期：2006-04-01 00:00:00

abstract：:The slope and pressure half-time of the aortic regurgitant velocity spectrum have been used as non-invasive markers of regurgitant severity. Recent in vitro and theoretical work, however, has suggested a confounding effect of systemic vascular resistance and left ventricular compliance on these parameters. To study th...

journal_title：European heart journal

authors： Griffin BP,Flachskampf FA,Reimold SC,Lee RT,Thomas JD

更新日期：1994-05-01 00:00:00

abstract：AIMS:Trans-fatty acids (TFAs) are generated by the food industry and also occur naturally in trace amounts in dairy products. For the latter, beneficial health effects have been claimed, while there are numerous reports about TFA of industrial origin being hazardous to human health. Therefore, we aimed to investigate t...

journal_title：European heart journal

authors： Kleber ME,Delgado GE,Lorkowski S,März W,von Schacky C

更新日期：2016-04-01 00:00:00

abstract：:Promising approaches towards new therapeutic strategies in coronary heart disease might emerge from an improved pathophysiological understanding of the role of certain peptides, which require a localizing event for their accumulation or expression in the coronary vasculature. Temporal myocardial ischaemia or hypoperfu...

journal_title：European heart journal

authors： Holtz J,Goetz RM

更新日期：1991-12-01 00:00:00

abstract：AIMS:To evaluate the accuracy of echocardiography in conjunction with quantitative high-dose dipyridamole technetium-99m sestamibi tomography (SPECT) in detecting coronary allograft vasculopathy. METHODS AND RESULTS:Seventy-eight consecutive heart transplant recipients underwent echocardiography while at rest and high...

journal_title：European heart journal

authors： Ciliberto GR,Ruffini L,Mangiavacchi M,Parolini M,Sara R,Massa D,De Maria R,Gronda E,Vitali E,Parodi O

更新日期：2001-06-01 00:00:00

abstract：:To assess the value of exercise stress testing and of mental stress as predictors of hypertension, we studied 130 normotensive males 14-18 years of age. Sixty-five had at least one hypertensive parent (SHT), while 65 had normotensive parents (SNT). Systolic (SBP) and diastolic (DBP) blood pressure, rate-pressure produ...

journal_title：European heart journal

authors： Radice M,Alli C,Avanzini F,Di Tullio M,Mariotti G,Taioli E,Zussino A,Folli G

更新日期：1985-06-01 00:00:00

abstract：AIMS:A substantial number of patients with dysfunctional but potentially viable myocardium cannot be accurately evaluated by transthoracic echocardiography due to a poor acoustic window. This study compares the diagnostic value of alternative functional imaging techniques, such as dobutamine-transoesophageal echocardio...

journal_title：European heart journal

authors： Baer FM,Theissen P,Crnac J,Schmidt M,Deutsch HJ,Sechtem U,Schicha H,Erdmann E

更新日期：2000-06-01 00:00:00

abstract：AIMS:Rotablation is a widely used technique for the treatment of complex coronary artery lesions but is so far only poorly supported by controlled studies. The Comparison of Balloon-Angioplasty versus Rotational Atherectomy study (COBRA) is a multicentre, prospective, randomized trial to compare short- and long-term ef...

journal_title：European heart journal

authors： Dill T,Dietz U,Hamm CW,Küchler R,Rupprecht HJ,Haude M,Cyran J,Ozbek C,Kuck KH,Berger J,Erbel R

更新日期：2000-11-01 00:00:00

abstract：:Transesophageal echocardiographic evaluation of right and left pulmonary arteries, up to the origin of their lobar branches, was prospectively performed with a single plane probe in 32 consecutive patients (18 M, 14 F, aged 55.5 +/- 14.6, from 32 to 80 years) with clinical or echocardiographic suspicion of pulmonary e...

journal_title：European heart journal

authors： Pruszczyk P,Torbicki A,Kuch-Wocial A,Chlebus M,Miśkiewicz ZC,Jedrusik P

更新日期：1995-04-01 00:00:00

abstract：:The generation of abnormal gradients between the apical cavity and the subaortic valvular region of the left ventricle in patients with hypertrophic cardiomyopathy (HCM) has traditionally been equated to a dynamic obstruction to left ventricular outflow. To examine this concept in more detail, left ventricular ejectio...

journal_title：European heart journal

authors： Murgo JP,Alter BR,Dorethy JF,Altobelli SA,Craig WE,McGranahan GM Jr

更新日期：1983-11-01 00:00:00

abstract：:Eleven patients with an atrioventricular accessory pathway were studied by programmed electrical stimulation to determine if reentrant tachycardia could be prevented by delivery of either a single atrial extrastimulus, applied at a critical time after the tachycardia-initiating stimulus (or stimuli), or a train of sti...

journal_title：European heart journal

authors： Kuck KH,Kunze KP,Schlüter M,Bleifeld W

更新日期：1985-01-01 00:00:00

abstract：:A 35-year-old man developed giant cell myocarditis resulting in severe congestive cardiac failure. He needed urgent orthotopic cardiac transplantation despite maximal doses of inotropes and augmentation with an intra-aortic balloon pump. The patient presented with rhythm disturbances and echocardiographically diminish...

journal_title：European heart journal

authors： Kong G,Madden B,Spyrou N,Pomerance A,Mitchell A,Yacoub M

更新日期：1991-04-01 00:00:00

abstract：:Mechanisms of ventricular arrhythmias were assessed by the application of ECG criteria derived from experimental electrophysiology. These interval criteria describe for ideal and modulated parasystole, resetable spontaneous automaticity, early and delayed afterdepolarizations and reentry, how QRS complexes of ectopic ...

journal_title：European heart journal

authors： van Hemel NM,Swenne CA,Robles de Medina EO

更新日期：1987-08-01 00:00:00

abstract：AIMS:No-reflow after a primary percutaneous coronary intervention (PCI) is associated with a high incidence of left ventricular (LV) failure and a poor prognosis. Endothelin-1 (ET-1) is a potent endothelium-derived vasoconstrictor peptide and an important modulator of neutrophil function. Elevated systemic ET-1 levels ...

journal_title：European heart journal

authors： Niccoli G,Lanza GA,Shaw S,Romagnoli E,Gioia D,Burzotta F,Trani C,Mazzari MA,Mongiardo R,De Vita M,Rebuzzi AG,Lüscher TF,Crea F

更新日期：2006-08-01 00:00:00

abstract：AIMS:Recent randomized trials suggest that intensive glycaemic control fails to reduce heart failure-related events in patients with diabetes. The molecular cues underlying persistent myocardial damage despite normoglycaemia restoration remain elusive. MicroRNAs (miRNAs), a class of small non-coding RNAs, orchestrate t...

journal_title：European heart journal

authors： Costantino S,Paneni F,Lüscher TF,Cosentino F

更新日期：2016-02-07 00:00:00

abstract：AIMS:To determine the potential adjunct of high-sensitivity (hs) C-reactive protein for risk stratification in patients with stable congestive heart failure (CHF). METHODS AND RESULTS:We studied 546 consecutive patients clinically stable with an ejection fraction <45% who were referred to our centre for evaluation of ...

journal_title：European heart journal

authors： Lamblin N,Mouquet F,Hennache B,Dagorn J,Susen S,Bauters C,de Groote P

更新日期：2005-11-01 00:00:00

abstract：:Activation of the sympathetic nervous system may contribute to the renal vasoconstriction and sodium retention seen in congestive heart failure. Previous studies in congestive heart failure patients employing large doses of prazosin that lowered systemic blood pressure have been generally disappointing. The renal haem...

journal_title：European heart journal

authors： Lang CC,Choy AM,Rahman AR,Struthers AD

更新日期：1993-09-01 00:00:00

abstract：AIMS:Sudden unexplained death syndrome occurs in previously healthy South-east Asian young adults without any structural cause of death. The common electrocardiographic (ECG) change in sudden unexplained death syndrome survivors is right bundle branch block and ST elevations in leads V(1) to V(3), which are similar to ...

journal_title：European heart journal

authors： Sangwatanaroj S,Prechawat S,Sunsaneewitayakul B,Sitthisook S,Tosukhowong P,Tungsanga K

更新日期：2001-12-01 00:00:00

abstract：AIMS:Kinetics of recovery oxygen consumption after exercise plays an important role in determining exercise capacity. This study was performed to assess the kinetics of recovery oxygen consumption in mitral stenosis and evaluate the effects of percutaneous balloon mitral valvuloplasty and exercise training on the kinet...

journal_title：European heart journal

authors： Lim HY,Lee CW,Park SW,Kim JJ,Song JK,Hong MK,Jin YS,Park SJ

更新日期：1998-12-01 00:00:00

abstract：:Measurement of the pre-ejection period (PEP) can give valuable information on myocardial function in rats. Depressed cardiac function is accompanied by prolongation of PEP, which shortens when cardiac function improves. Left ventricular ejection time (LVET) may be shortened with ageing in spontaneously hypertensive ra...

journal_title：European heart journal

authors： Schoemaker RG,Smits JF

更新日期：1990-12-01 00:00:00

abstract：:Congestive heart failure is the most common cause of death in young adults with thalassaemia major. In the present study we compared atrial natriuretic peptide levels (ANP) in 30 asymptomatic patients with thalassaemia major (aged 16.6 +/- 6.4 years), normal left ventricular diastolic cavity dimension and systolic fun...

journal_title：European heart journal

authors： Derchi G,Bellone P,Forni GL,Lupi G,Jappelli S,Randazzo M,Zino V,Vecchio C

更新日期：1992-10-01 00:00:00

abstract：:Between 1968 and 1984, 78 patients (mean age 43, range 14 to 65 years) underwent combined aortic, mitral and tricuspid surgery (22 triple valve replacements, 56 aortic valve replacements with tricuspid conservative surgery and mitral valve replacement (N = 48), or commissuroplasty (N = 8). Pre-operative consequences o...

journal_title：European heart journal

authors： Michel PL,Houdart E,Ghanem G,Badaoui G,Hage A,Acar J

更新日期：1987-05-01 00:00:00