A double-blind comparison of the long-term efficacy of a potassium channel opener and a calcium antagonist in stable angina pectoris.

abstract：AIMS:Exposure of tissue factor (TF) is a critical proximal step in the pathogenesis of acute coronary syndromes. Sunol-cH36, a chimaeric monoclonal antibody to TF, blocks binding of factor X to the TF:VIIa complex. This report describes the first completed trial of Sunol-cH36 in humans. METHODS AND RESULTS:We assessed...

journal_title：European heart journal

authors： Morrow DA,Murphy SA,McCabe CH,Mackman N,Wong HC,Antman EM

更新日期：2005-04-01 00:00:00

abstract：AIMS:Atrial fibrillation (AF) is a common complication in patients with acute myocardial infarction and is associated with an increase in the risk of death. The excess mortality associated with AF complicating acute myocardial infarction has not been studied in detail. Observations indicate that AF facilitates inductio...

journal_title：European heart journal

authors： Pedersen OD,Abildstrøm SZ,Ottesen MM,Rask-Madsen C,Bagger H,Køber L,Torp-Pedersen C,TRACE Study Investigators.

更新日期：2006-02-01 00:00:00

abstract：AIMS:We investigated the temporal changes in circulating levels of markers of extracellular cardiac matrix (ECCM) turnover and their relationship with infarct size (IS), ejection fraction (EF), and left ventricular (LV) volumes, determined by serial cardiac magnetic resonance (CMR) imaging in patients with first-time S...

journal_title：European heart journal

authors： Manhenke C,Ueland T,Jugdutt BI,Godang K,Aukrust P,Dickstein K,Ørn S

更新日期：2014-02-01 00:00:00

abstract：AIMS:Subjects with lipoprotein(a) [Lp(a)] elevation have increased arterial wall inflammation and cardiovascular risk. In patients at increased cardiovascular risk, arterial wall inflammation is reduced following lipid-lowering therapy by statin treatment or lipoprotein apheresis. However, it is unknown whether lipid-l...

journal_title：European heart journal

authors： Stiekema LCA,Stroes ESG,Verweij SL,Kassahun H,Chen L,Wasserman SM,Sabatine MS,Mani V,Fayad ZA

更新日期：2019-09-01 00:00:00

abstract：AIMS:Despite advances in the treatment of acute coronary syndromes based on randomized trial data and published guidelines, the extent to which such treatments are applied in practice remains uncertain. Data from clinical trials derive from selected geographical areas and in highly selected populations of patients, and...

journal_title：European heart journal

authors： Fox KA,Goodman SG,Klein W,Brieger D,Steg PG,Dabbous O,Avezum A

更新日期：2002-08-01 00:00:00

abstract：AIMS:LV reverse remodelling has been shown to be a favourable response after cardiac resynchronization therapy (CRT) in many clinical trials. This study investigated whether left ventricular (LV) reverse remodelling after CRT has any structural benefit, which include the improvement of LV mass or regional wall thicknes...

journal_title：European heart journal

authors： Zhang Q,Fung JW,Auricchio A,Chan JY,Kum LC,Wu LW,Yu CM

更新日期：2006-06-01 00:00:00

abstract：AIMS:To evaluate the effects of simvastatin only or combined with continuous hormone replacement therapy on the serum lipid profile in hypercholesterolaemic post-menopausal women. METHODS AND RESULTS:One hundred hypercholesterolaemic post-menopausal women were given either simvastatin 10 mg daily together with oestrog...

journal_title：European heart journal

authors： Fak AS,Erenus M,Tezcan H,Caymaz O,Atagündüz P,Oktay S,Oktay A

更新日期：2000-02-01 00:00:00

abstract：:The European Myocardial Infarction Project (E.M.I.P.) participants have evaluated out-of-hospital coronary care services in different cities within the E.E.C. and concluded that these facilities would support a study within these European centres on pre-hospital intervention in myocardial infarction. Based on a pilot ...

journal_title：European heart journal

authors：

更新日期：1988-02-01 00:00:00

abstract：:Sequential alterations of left ventricular volumes and haemodynamics were studied in 29 patients between 4 days and 4 weeks after myocardial infarction. Left ventricular volume was determined by single photon emission computerized tomography (SPECT), infarct size by creatine kinase (CK) analysis, angiography and thall...

journal_title：European heart journal

authors： Gaudron P,Eilles C,Ertl G,Kochsiek K

更新日期：1990-04-01 00:00:00

abstract：:The steady state plasma concentrations of the two platelet-specific proteins beta-thromboglobulin (BTG) and platelet factor 4 (PF4) were determined in two groups of females: 36 acute myocardial infarction (AMI) survivors, and 38 age-matched control subjects. For the AMI patients the mean BTG and PF4 values were 57 +/-...

journal_title：European heart journal

authors： Kutti J,Johansson S,Eriksson KA,Sigvaldason A,Vedin A,Wadenvik H,Wilhelmsson C

更新日期：1983-05-01 00:00:00

abstract：:To evaluate gender-related differences in left ventricular (LV) structure and function in aortic stenosis, LV biplane cineangiography, micromanometry and endomyocardial biopsies were carried out in 56 patients with aortic stenosis and normal coronary arteries. Patients were divided into males (M: n = 35), and females ...

journal_title：European heart journal

authors： Villari B,Campbell SE,Schneider J,Vassalli G,Chiariello M,Hess OM

更新日期：1995-10-01 00:00:00

abstract：:To assess possible clinical and angiographic factors associated with acute coronary events following PTCA, we performed quantitative angiography in 168 consecutive patients who had undergone successful angioplasty in a native vessel (94 for stable angina, 74 for unstable angina), and who were restudied (24 +/- 15 week...

journal_title：European heart journal

authors： Chen L,Leatham E,Chester M,Huang J,Kaski JC

更新日期：1995-08-01 00:00:00

abstract：AIMS:Raised blood pressure (BP) is the biggest contributor to mortality and disease burden worldwide and fewer than half of those with hypertension are aware of it. May Measurement Month (MMM) is a global campaign set up in 2017, to raise awareness of high BP and as a pragmatic solution to a lack of formal screening wo...

journal_title：European heart journal

authors： Beaney T,Burrell LM,Castillo RR,Charchar FJ,Cro S,Damasceno A,Kruger R,Nilsson PM,Prabhakaran D,Ramirez AJ,Schlaich MP,Schutte AE,Tomaszewski M,Touyz R,Wang JG,Weber MA,Poulter NR,MMM Investigators.

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Following hospitalization with a range of cardiovascular disorders, substantial variation has been noted in clinical outcome, both between and within countries. OBJECTIVES:To examine the variation, between hospitals, in the clinical outcomes of death and readmission following hospitalization with heart fail...

journal_title：European heart journal

authors： Stewart S,Demers C,Murdoch DR,McIntyre K,MacLeod ME,Kendrick S,Capewell S,McMurray JJ

更新日期：2002-04-01 00:00:00

abstract：AIMS:We sought to investigate the factors associated with restenosis and its potential association with late clinical deterioration after successful percutaneous mitral valvuloplasty (PMV). METHODS AND RESULTS:We analysed echocardiographic (median 74 months) and clinical (median 109 months) follow-up data of 329 patie...

journal_title：European heart journal

authors： Song JK,Song JM,Kang DH,Yun SC,Park DW,Lee SW,Kim YH,Lee CW,Hong MK,Kim JJ,Park SW,Park SJ

更新日期：2009-05-01 00:00:00

abstract：AIMS:The aim of this study is to compare the efficacy of sirolimus-eluting stents (SES) on neointimal growth and vessel remodelling for in-stent restenosis versus de novo coronary artery lesions using serial intravascular ultrasound (IVUS). METHODS AND RESULTS:The study population consisted of 86 patients with in-sten...

journal_title：European heart journal

authors： Degertekin M,Lemos PA,Lee CH,Tanabe K,Sousa JE,Abizaid A,Regar E,Sianos G,van der Giessen WJ,de Feyter PJ,Wuelfert E,Popma JJ,Serruys PW

更新日期：2004-01-01 00:00:00

abstract：AIMS:To assess the impact of MultiPoint™ Pacing (MPP)-programmed according to the physician's discretion-in non-responders to standard biventricular pacing after 6 months. METHODS AND RESULTS:The study enrolled 1921 patients receiving a quadripolar cardiac resynchronization therapy (CRT) system capable of MPP™ therapy...

journal_title：European heart journal

authors： Leclercq C,Burri H,Curnis A,Delnoy PP,Rinaldi CA,Sperzel J,Lee K,Calò L,Vicentini A,Concha JF,Thibault B

更新日期：2019-09-14 00:00:00

abstract：:A previously described nitroglycerin-induced heparin resistance could not be verified by in-vitro experiments or in a randomized, double-blind, crossover trial in healthy volunteers. A clinically relevant attenuation of the anticoagulant effect of a heparin bolus (40 U.kg-1) by a concomitant infusion of nitroglycerin ...

journal_title：European heart journal

authors： Schoenenberger RA,Ménat L,Weiss P,Marbet GA,Ritz R

更新日期：1992-03-01 00:00:00

abstract：AIMS:Patients with chronic heart failure (CHF) exhibit detrimental changes in skeletal muscle that contribute to their impaired physical performance. This study investigates the possibility of counteracting these changes by chronic low-frequency electrical stimulation (CLFS) of left and right thigh muscles. METHODS AN...

journal_title：European heart journal

authors： Nuhr MJ,Pette D,Berger R,Quittan M,Crevenna R,Huelsman M,Wiesinger GF,Moser P,Fialka-Moser V,Pacher R

更新日期：2004-01-01 00:00:00

abstract：Aims:To characterize the relationship between blood pressure (BP) or heart rate and mortality and morbidity in chronic obstructive pulmonary disease (COPD). Methods and results:We performed post hoc analysis of baseline BP or heart rate and all-cause mortality and cardiovascular events in the SUMMIT trial. SUMMIT was ...

journal_title：European heart journal

authors： Byrd JB,Newby DE,Anderson JA,Calverley PMA,Celli BR,Cowans NJ,Crim C,Martinez FJ,Vestbo J,Yates J,Brook RD,SUMMIT Investigators.

更新日期：2018-09-01 00:00:00

abstract：:Among 369 patients with native valve infective endocarditis observed during a 14-year period, 17 were related to S: pneumoniae. Fourteen of them were observed in the last 7 years. At the time of admission 13 exhibited purulent meningitis, 6 of them being comatose. An apparent portal of entry was present in 13 patients...

journal_title：European heart journal

authors： Wolff M,Regnier B,Witchitz S,Gibert C,Amoudry C,Vachon F

更新日期：1984-10-01 00:00:00

abstract：:The incidence of cardiogenic shock (CS) has increased remarkably over the past decade and remains a challenging condition with mortality rates of ∼50%. Cardiogenic shock encompasses cardiac contractile dysfunction; however, it is also a multiorgan dysfunction syndrome, often complicated by a systemic inflammatory resp...

journal_title：European heart journal

authors： Iborra-Egea O,Rueda F,García-García C,Borràs E,Sabidó E,Bayes-Genis A

更新日期：2020-10-14 00:00:00

abstract：Aim:Studies have reported less favourable outcomes in women compared with men after primary percutaneous coronary intervention (PCI) in ST-segment elevation myocardial infarction (STEMI). Whether sex-specific differences in the magnitude or prognostic impact of infarct size or post-infarction cardiac function explain t...

journal_title：European heart journal

authors： Kosmidou I,Redfors B,Selker HP,Thiele H,Patel MR,Udelson JE,Magnus Ohman E,Eitel I,Granger CB,Maehara A,Kirtane A,Généreux P,Jenkins PL,Ben-Yehuda O,Mintz GS,Stone GW

更新日期：2017-06-01 00:00:00

abstract：:Although the number of individuals reaching 80 who are considered to be healthy is increasing, the very elderly are likely to have long-term conditions, to report symptoms and/or be taking at least one regular medication. The impact of antihypertensive treatment has to be taken into account in this context. The treatm...

journal_title：European heart journal

authors： Peters R,Beckett N,McCormack T,Fagard R,Fletcher A,Bulpitt C

更新日期：2014-07-01 00:00:00

abstract：AIMS:The role of aspirin in the primary prevention setting is continuously evolving. Recent randomized trials have challenged the role of aspirin in the primary prevention setting. METHODS AND RESULTS:Electronic databases were searched for randomized trials that compared aspirin vs. placebo (or control) in subjects wi...

journal_title：European heart journal

authors： Mahmoud AN,Gad MM,Elgendy AY,Elgendy IY,Bavry AA

更新日期：2019-02-14 00:00:00

abstract：AIMS:Cardioprotective effects of erythropoietin (EPO) have been shown in experimental and smaller clinical studies. We performed a prospective, multicentre, randomized trial to assess the effects of a single high dose of EPO after primary coronary intervention (PCI) for an ST-elevation myocardial infarction (STEMI). Me...

journal_title：European heart journal

authors： Voors AA,Belonje AM,Zijlstra F,Hillege HL,Anker SD,Slart RH,Tio RA,van 't Hof A,Jukema JW,Peels HO,Henriques JP,Ten Berg JM,Vos J,van Gilst WH,van Veldhuisen DJ,HEBE III Investigators.

更新日期：2010-11-01 00:00:00

abstract：AIMS:To evaluate clinical disease expression, non-invasive diagnosis, and prognosis in families with dominant vs. recessive arrhythmogenic right ventricular cardiomyopathy (ARVC) due to mutations in related desmosomal proteins plakophilin-2 (PKP2) and plakoglobin (JUP), respectively. METHODS AND RESULTS:One hundred an...

journal_title：European heart journal

authors： Antoniades L,Tsatsopoulou A,Anastasakis A,Syrris P,Asimaki A,Panagiotakos D,Zambartas C,Stefanadis C,McKenna WJ,Protonotarios N

更新日期：2006-09-01 00:00:00

abstract：:Left ventricular (LV) filling as assessed by Doppler transmitral flow velocity measurements was studied in 20 male patients with coronary artery disease (CAD) and in 18 normal individuals. Stroke volume, blood pressure and heart rate in the two groups were not significantly different. Compared to normals, the ratio be...

journal_title：European heart journal

authors： Myreng Y,Ihlen H,Nitter-Hauge S

更新日期：1988-11-01 00:00:00

abstract：:A twenty-first century model for the training and assessment of cardiac interventionists’ skills, outlined by Prof. John Morgan FRCP FESC. ...

journal_title：European heart journal

authors： Morgan JM,Burri H,Binner L,Mansour H,Retzlaff H,Roca M,Gallagher A

更新日期：2011-01-01 00:00:00

abstract：AIMS:Monocytes are critical mediators of healing following acute myocardial infarction (AMI), making them an interesting target to improve myocardial repair. The purpose of this study was a gain of insight into the source and recruitment of monocytes following AMI in humans. METHODS AND RESULTS:Post-mortem tissue spec...

journal_title：European heart journal

authors： van der Laan AM,Ter Horst EN,Delewi R,Begieneman MP,Krijnen PA,Hirsch A,Lavaei M,Nahrendorf M,Horrevoets AJ,Niessen HW,Piek JJ

更新日期：2014-02-01 00:00:00