Time-to-treatment significantly affects the extent of ST-segment resolution and myocardial blush in patients with acute myocardial infarction treated by primary angioplasty.

abstract：:In the adult cardiac myocyte the functional and structural integrity of the sarcolemma depends on the presence of calcium ions in the extracellular fluid. Ultrastructural damage to the myocardial cell after Ca is repleted following brief periods of Ca depletion includes (1) sarcolemmal disruption, (2) mitochondrial da...

journal_title：European heart journal

authors： Frank JS

更新日期：1983-12-01 00:00:00

abstract：AIMS:Growth-differentiation factor-15 (GDF-15) has emerged as a biomarker of increased mortality and recurrent myocardial infarction (MI) in patients diagnosed with non-ST-elevation acute coronary syndrome. We explored the usefulness of GDF-15 for early risk stratification in 479 unselected patients with acute chest pa...

journal_title：European heart journal

authors： Eggers KM,Kempf T,Allhoff T,Lindahl B,Wallentin L,Wollert KC

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:In patients with postinfarction sustained ventricular tachycardia showing one or more antiarrhythmic drug failures, the question is how long to proceed with new drug trials before deciding to perform map-guided arrhythmia surgery. Although the techniques of this surgery developed rapidly in the early 1980s, ...

journal_title：European heart journal

authors： van Hemel NM,Kingma JH,Defauw JJ,Hoogteijling-van Dusseldorp E,Kelder JC,Beukema WP,Vermeulen FE

更新日期：1996-04-01 00:00:00

abstract：:Between 1968 and 1984, 78 patients (mean age 43, range 14 to 65 years) underwent combined aortic, mitral and tricuspid surgery (22 triple valve replacements, 56 aortic valve replacements with tricuspid conservative surgery and mitral valve replacement (N = 48), or commissuroplasty (N = 8). Pre-operative consequences o...

journal_title：European heart journal

authors： Michel PL,Houdart E,Ghanem G,Badaoui G,Hage A,Acar J

更新日期：1987-05-01 00:00:00

abstract：:The author reviews statistical methods commonly applied in economic evaluations that rely on individual patient-level data. The paper includes a review of foundational concepts, unique characteristics of health economic data, and methods developed to address them. The paper then highlights issues that should be consid...

journal_title：European heart journal

authors： Reed SD

更新日期：2014-07-01 00:00:00

abstract：:This overview provides a Europe-wide update on the current burden of cardiovascular disease, and specifically of coronary heart disease and stroke. Cardiovascular disease continues to cause a large proportion of deaths and disability in Europe, and places a substantial burden on the health care systems and economies o...

journal_title：European heart journal

authors： Nichols M,Townsend N,Scarborough P,Rayner M

更新日期：2013-10-01 00:00:00

abstract：:Three different bradycardic agents, alinidine, AQ-A39 and UL-FS49 increase the intrinsic cycle length of the isolated SA node preparation of the rabbit. This increase is mainly caused by a decrease in rate of diastolic depolarization. One of these agents, alinidine, was used to study the underlying ionic mechanism of ...

journal_title：European heart journal

authors： van Ginneken AC,Bouman LN,Jongsma HJ,Duivenvoorden JJ,Opthof T,Giles WR

更新日期：1987-12-01 00:00:00

abstract：:An exercise test was performed in 455 patients in the third week after acute myocardial infarction (AMI). One hundred and seventeen (26%) of them were considered as having a complicated AMI. During a follow-up of 4.5 years their mortality was 49% vs 23% in the remaining patients with uncomplicated AMI. The survival of...

journal_title：European heart journal

authors： Saunamaki KI,Andersen JD

更新日期：1987-06-01 00:00:00

abstract：AIMS:To compare the precursor of atrial and brain natriuretic peptide (N-ANP, N-BNP), brain natriuretic peptide (BNP), big endothelin-1, the 6-min walk test and the Minnesota Living with Heart Failure Questionnaire (LHFQ) with regard to short-term outcome in an ambulatory heart failure population. METHODS AND RESULTS:...

journal_title：European heart journal

authors： Hülsmann M,Berger R,Sturm B,Bojic A,Woloszczuk W,Bergler-Klein J,Pacher R

更新日期：2002-06-01 00:00:00

abstract：AIMS:To investigate whether the benefit of thrombolytic therapy was sustained beyond the first decade. We report the 10-14 year outcome of 533 patients who were randomized to treatment with intracoronary streptokinase or to conventional therapy during the years 1980-1985. METHODS AND RESULTS:Details of survival and ca...

journal_title：European heart journal

authors： Maas AC,van Domburg RT,Deckers JW,Vermeer F,Remme WJ,Kamp O,Manger Cats V,Simoons ML

更新日期：1999-06-01 00:00:00

abstract：:Among 101 consecutive patients operated on for native infective aortic valve endocarditis (53 males, 48 females, mean age 39 years), 69 presented various forms of infectious extension to the surrounding areas. Twenty-six lesions were noted in the aortic roots: 18 annular abscesses, one abscess of the Valsalva sinus an...

journal_title：European heart journal

authors： Amrani M,Schoevaerdts JC,Eucher P,Nicolas AL,Dion R,Kremer R

更新日期：1995-04-01 00:00:00

abstract：:The effects of fentanyl at a dose of 100 micrograms.kg-1 on cardiac automaticity, refractoriness and conduction have been studied in a model of heterotopic heart transplantation which combines a denervated heart (donor) and a non-denervated heart (recipient) in each of 20 dogs employed. Once the surgical procedure had...

journal_title：European heart journal

authors： Alvarez L,Escudero C,Carmona JA,Silva L,Castillo-Olivares JL

更新日期：1992-09-01 00:00:00

abstract：:To investigate the antianginal efficacy and tolerability of felodipine, a new dihydropyridine calcium antagonist, 20 patients with stable exertional angina, not completely controlled by beta-blocker monotherapy, entered a randomized, double-blind, placebo-controlled, crossover study. Patients on standard beta-blocker ...

journal_title：European heart journal

authors： Sangiorgio P,Di Pasquale G,Savonitto S,Urbinati S,Rubboli A,Cavallotti G,Pinelli G,Bracchetti D

更新日期：1990-11-01 00:00:00

abstract：AIM:To define the long-term outcome of patients presenting with acute coronary syndrome [ST-segment elevation myocardial infarction (STEMI), and non-STEMI and unstable angina acute coronary syndrome (ACS) without biomarker elevation] and to test the hypothesis that the GRACE (Global Registry of Acute Coronary Events) r...

journal_title：European heart journal

authors： Fox KA,Carruthers KF,Dunbar DR,Graham C,Manning JR,De Raedt H,Buysschaert I,Lambrechts D,Van de Werf F

更新日期：2010-11-01 00:00:00

abstract：AIMS:Major guidelines recommend lowering systolic blood pressure (SBP) to <140 mmHg in all hypertensives, but evidence is missing whether this is beneficial in (i) uncomplicated hypertensives, (ii) grade 1 hypertensives, and (iii) elderly hypertensives. Providing this missing evidence is important to justify efforts an...

journal_title：European heart journal

authors： Zhang Y,Zhang X,Liu L,Zanchetti A,FEVER Study Group.

更新日期：2011-06-01 00:00:00

abstract：:After single chamber atrial pacemaker implantation, serial electrophysiologic studies were performed noninvasively at intervals of 3 months over a total period of 3 years in 24 patients with symptomatic sinus node dysfunction. All patients underwent invasive electrophysiologic studies before pacemaker implantation and...

journal_title：European heart journal

authors： van Mechelen R,Segers A,Hagemeijer F

更新日期：1984-08-01 00:00:00

abstract：AIMS:The results of the West of Scotland Coronary Prevention Study (WOSCOPS) demonstrated the clinical benefit of using pravastatin for the primary prevention of cardiovascular disease in hypercholesterolaemic men. To inform decision makers, who must also consider costs, this study assesses the economic efficiency of s...

journal_title：European heart journal

authors： Caro J,Klittich W,McGuire A,Ford I,Pettitt D,Norrie J,Shepherd J

更新日期：1999-02-01 00:00:00

abstract：Aims:The choice between initiating a non-vitamin K antagonist oral anticoagulant (NOAC) and a vitamin K antagonist (VKA) in patients with atrial fibrillation (AF) may be challenging. To assist in this decision, we developed a risk score to identify patients for whom a therapeutic benefit of NOACs over VKA is predicted....

journal_title：European heart journal

authors： Fanola CL,Giugliano RP,Ruff CT,Trevisan M,Nordio F,Mercuri MF,Antman EM,Braunwald E

更新日期：2017-03-21 00:00:00

abstract：AIMS:microRNA (miRNA) is reported to be present in the blood of humans and has been increasingly suggested as a biomarker for diseases. We aim to determine the potential of cardiac-specific miRNAs in circulation to serve as biomarkers for acute myocardial infarction (AMI). METHODS AND RESULTS:By verifying their tissue...

journal_title：European heart journal

authors： Wang GK,Zhu JQ,Zhang JT,Li Q,Li Y,He J,Qin YW,Jing Q

更新日期：2010-03-01 00:00:00

abstract：:Thrombolytic treatment efficacy is greater when the delay between onset of pain and treatment is short. One way to shorten this delay is to give treatment at home, but one cannot recommend this technique if it has not been demonstrated first, that pre-hospital thrombolysis is feasible and safe, and second, that it is ...

journal_title：European heart journal

authors： Castaigne AD,Hervé C,Duval-Moulin AM,Gaillard M,Dubois-Randé JL,Lellouche D

更新日期：1990-08-01 00:00:00

abstract：:Peptides produced by the renin-angiotensin system play a major role in the development and progression of various cardiovascular diseases. One of these peptides, angiotensin II, is a potent vasoconstrictor that exerts most of its effects through the human AT1 receptor. Following the discovery of a functional variation...

journal_title：European heart journal

authors： van Geel PP,Pinto YM,Buikema H,van Gilst WH

更新日期：1998-07-01 00:00:00

abstract：:A patient with a three-year history of recurrent pulmonary embolism is presented. Thromboembolic pulmonary hypertension was proven in the final stage of disease in the presence of repeated episodes of systemic embolic events. Paradoxical embolism was assumed to be present on the basis of blood-gas analysis and contras...

journal_title：European heart journal

authors： Lang I,Steurer G,Weissel M,Burghuber OC

更新日期：1988-06-01 00:00:00

abstract：:Strong experimental evidence links ventricular fibrillation to an increased temporal dispersion of the recovery of excitability. The effect of an overall prolongation of repolarization and an increased basic dispersion of repolarization on premature dispersion was studied on ventricular surface in 10 dogs. Our observa...

journal_title：European heart journal

authors： Amlie JP,Kuo CS,Munakata K,Reddy PS,Surawicz B

更新日期：1985-11-01 00:00:00

abstract：:Pulsed Doppler echocardiography was performed in 30 patients to assess the influence of mitral orifice area and velocity on the determination of mitral stroke volume and inflow. Aortic forward stroke volume and outflow were measured at the centre of the aortic annulus, and compared with mitral flow measurements calcul...

journal_title：European heart journal

authors： Tribouilloy C,Slama M,Shen WF,Choquet D,Delonca J,Mertl C,Dufosse H,Lesbre JP

更新日期：1991-01-01 00:00:00

abstract：AIMS:Left ventricular (LV) ejection fraction (LVEF) is currently considered for the decision making of patients with mitral regurgitation (MR). However, LVEF represents change in LV volume between end-diastole and end-systole but does not characterize the intrinsic function of the myocardium. In contrast, speckle-track...

journal_title：European heart journal

authors： Kamperidis V,Marsan NA,Delgado V,Bax JJ

更新日期：2016-03-07 00:00:00

abstract：:The effects of dexamethasone on cultured rat beating heart cells experimentally infected with coxsackievirus B2 were investigated at an early stage (1-3 days) post challenge. Changes in the release of the cardiac enzyme, aspartate amino-transferase (AST), beating %, cytopathic effect (CPE), virus titre, ultrastructure...

journal_title：European heart journal

authors： Yang YZ,Yuan WL,Guo Q,Gong ZX,Zhow TS,Shen JY,Chen HZ

更新日期：1991-08-01 00:00:00

abstract：:Ventricular arrhythmias present with strongly varying intensity. This spontaneous variability makes it difficult to use one of the existing arrhythmia grading systems for risk or therapy efficacy studies. We attempted to explain the variability by the changing autonomic, ischaemic, circadian, and rhythmic factors. Fou...

journal_title：European heart journal

authors： Janssen MJ,Swenne CA,Manger Cats V,van Bemmel JH,Bruschke AV

更新日期：1995-05-01 00:00:00

abstract：:Anthony N. DeMaria discusses the journal's history, its focus,and innovative ideas for Internet reading. ...

journal_title：European heart journal

authors： Taylor J

更新日期：2012-02-01 00:00:00

abstract：Aims:To elucidate the effects of intensive LDL-C lowering treatment with a standard dose of statin and ezetimibe in patients with dyslipidaemia and high risk of coronary events, targeting LDL-C less than 70 mg/dL (1.8 mmol/L), compared with standard LDL-C lowering lipid monotherapy targeting less than 100 mg/dL (2.6 mm...

journal_title：European heart journal

authors： Hagiwara N,Kawada-Watanabe E,Koyanagi R,Arashi H,Yamaguchi J,Nakao K,Tobaru T,Tanaka H,Oka T,Endoh Y,Saito K,Uchida T,Matsui K,Ogawa H

更新日期：2017-08-01 00:00:00

abstract：AIMS:Benefits and complications of postoperative implantable cardioverter-defibrillator tests are controversial matters. This study sought to assess the necessity of defibrillation function tests after implantation. METHODS AND RESULTS:We retrospectively analysed 1007 implantable cardioverter-defibrillator tests in 58...

journal_title：European heart journal

authors： Brunn J,Böcker D,Weber M,Castrucci M,Gradaus R,Borggrefe M,Breithardt G,Block M

更新日期：2000-01-01 00:00:00