Improvement of regional myocardial blood flow and function and reduction of infarct size with ivabradine: protection beyond heart rate reduction.

abstract：BACKGROUND:Antiarrhythmic drugs are still used for the treatment of ventricular tachyarrhythmias, in combination with implantable cardioverter-defibrillators or without them. AIM OF THE STUDY:In a double-blind randomized crossover design, the short- and long-term efficacy and safety of oral dofetilide or oral sotalol ...

journal_title：European heart journal

authors： Boriani G,Lubinski A,Capucci A,Niederle R,Kornacewicz-Jack Z,Wnuk-Wojnar AM,Borggrefe M,Brachmann J,Biffi M,Butrous GS,Ventricular Arrhythmias Dofetilide Investigators.

更新日期：2001-12-01 00:00:00

abstract：:We investigated cardiovascular and coronary responses to intravenous infusions of adrenaline, which raised arterial concentrations in a stepwise fashion from basal to about 5-6 nmol.l-1, in 11 non-rejecting heart transplanted patients, and in eight intact innervated subjects. Cardiac adrenaline extraction and noradren...

journal_title：European heart journal

authors： Roca J,Cruz Caturla M,Hjemdahl P,Masotti M,Ventura A,Oriol A,Crexells C

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to determine the sensitivity and specificity of new criteria proposed by Duke University for case definition of infective endocarditis as compared to the previously accepted Von Reyn criteria. PATIENTS:A total of 143 consecutive suspected cases of infective endocarditis in 137 f...

journal_title：European heart journal

authors： Cecchi E,Parrini I,Chinaglia A,Pomari F,Brusasco G,Bobbio M,Trinchero R,Brusca A

更新日期：1997-07-01 00:00:00

abstract：:Arbutamine (Gensia, Inc., San Diego, CA) is a newly-developed sympathomimetic agent specifically designed for cardiovascular stress testing. It has been successfully used for the detection of coronary artery disease in conjunction with electrocardiography, echocardiographic and radionuclide techniques. Arbutamine incr...

journal_title：European heart journal

authors： Armstrong WF,Bach DS

更新日期：1995-11-01 00:00:00

abstract：:Aortic stenosis is one of the most common forms of acquired valvular heart disease. The development of symptoms, namely syncope, angina, or heart failure, in patients with severe aortic stenosis predicts a high likelihood of mortality. Aortic valve replacement is the current standard of care. In truly asymptomatic pat...

journal_title：European heart journal

authors： Bhattacharyya S,Hayward C,Pepper J,Senior R

更新日期：2012-10-01 00:00:00

abstract：:We studied the effects of a chronic increase in flow and of chronic hypertension on regional pulmonary blood volume and extravascular lung density (lung tissue and interstitial water per unit thoracic volume) in one group of patients with intracardiac, left-to-right shunt and in another group with Eisenmenger's syndro...

journal_title：European heart journal

authors： Wollmer P,Rozkovec A,Rhodes CG,Allan RM,Maseri A

更新日期：1984-11-01 00:00:00

abstract：AIMS:To analyse whether the proportion of patients with lone atrial fibrillation engaged in chronic sport practice was higher than that observed in the general population. METHODS AND RESULTS:The records of 1160 patients, seen at the arrhythmia outpatient clinic, were reviewed. A total of 70 patients (6%) suffered lon...

journal_title：European heart journal

authors： Mont L,Sambola A,Brugada J,Vacca M,Marrugat J,Elosua R,Paré C,Azqueta M,Sanz G

更新日期：2002-03-01 00:00:00

abstract：:Thrombolytic therapy is a practical, effective approach to the management of acute myocardial infarction that is widely used in Europe today. Early European trials demonstrated a clear reduction in mortality in patients who received thrombolytic therapy compared with those given conventional treatment. The findings of...

journal_title：European heart journal

authors： Vahanian A

更新日期：1996-09-01 00:00:00

abstract：AIMS:To determine the effects of omega-3 polyunsaturated fatty acids (omega-3 PUFAs) from fish on the incidence of recurrent ventricular arrhythmia in implantable cardioverter defibrillator (ICD) patients by combining results from published trials. METHODS AND RESULTS:We searched in the Medline, EMBASE, and Cochrane d...

journal_title：European heart journal

authors： Brouwer IA,Raitt MH,Dullemeijer C,Kraemer DF,Zock PL,Morris C,Katan MB,Connor WE,Camm JA,Schouten EG,McAnulty J

更新日期：2009-04-01 00:00:00

abstract：AIMS:Treatment of atrial fibrillation remains a major clinical challenge owing to the limited efficacy and safety of anti-arrhythmic drugs, particularly in patients with structural heart disease. METHODS AND RESULTS:To evaluate the efficacy of azimilide, a new class III anti-arrhythmic drug, we studied 658 patients wi...

journal_title：European heart journal

authors： Lombardi F,Borggrefe M,Ruzyllo W,Lüderitz B,A-COMET-II Investigators.

更新日期：2006-09-01 00:00:00

abstract：:A 37-year-old man sustained occlusion of the right coronary artery after a bicycle accident with blunt chest trauma over the left scapula. Acute coronary angiography was performed because of chest pain and ST-segment elevation. Despite surgically successful acute revascularization the patient developed a transmural in...

journal_title：European heart journal

authors： Gustavsson CG,Albrechtsson U,Forslind K,Ståhl E,White T

更新日期：1992-01-01 00:00:00

abstract：AIM:Estrogens regulate several biological processes involved in the pathogenesis of myocardial infarction. Catechol-O-methyltransferase (COMT) is a key enzyme in the degradation of estrogens. There is a functional polymorphism in the COMT gene (Val158Met), affecting the activity of the enzyme. We investigated if the lo...

journal_title：European heart journal

authors： Eriksson AL,Skrtic S,Niklason A,Hultén LM,Wiklund O,Hedner T,Ohlsson C

更新日期：2004-03-01 00:00:00

abstract：:Myocardial protection and the control of ischemic injury has been highly successful clinically in the field of cardiac surgery where hearts are made globally ischemic. By contrast, protection of the regionally ischemic myocardium, as found during evolving myocardial infarction, has been less successful and, despite nu...

journal_title：European heart journal

authors： Hearse DJ

更新日期：1983-05-01 00:00:00

abstract：:Aims To assess whether coronary flow velocity reserve following stent implantation is predictive of the subsequent need of target lesion revascularization. Methods and Results The outcome was examined of 417 patients enrolled in a multicentre prospective randomized study (DESTINI), who received a successful single ves...

journal_title：European heart journal

authors： Nishida T,Di Mario C,Kern MJ,Anderson TJ,Moussa I,Bonan R,Muramatsu T,Jain AC,Suarez de Lezo J,Cho SY,Meredith IT,Moses JW,Colombo A

更新日期：2002-02-01 00:00:00

abstract：AIMS:Chronic kidney disease (CKD) was found to be an independent risk factor for all-cause mortality as well as adverse cardiovascular disease (CVD) events in high-risk populations. Findings from population-based studies are scarce and inconsistent. We investigated the gender-specific association of CKD with all-cause ...

journal_title：European heart journal

authors： Meisinger C,Döring A,Löwel H,KORA Study Group.

更新日期：2006-05-01 00:00:00

abstract：AIMS:The study set out to assess the relative contributions of donor heart rate, respiration and recipient atrial contraction on the mean of pulsed wave transmitral Doppler flow indices in orthotopic heart transplant recipients. This would provide information on the theoretical usefulness of pacemaker synchronization o...

journal_title：European heart journal

authors： Mannaerts H,Balk A,Roelandt J

更新日期：1997-10-01 00:00:00

abstract：:Guidelines for the management of cardiovascular disease (CVD) stress the importance of treating global risk, rather than individual risk, factors. Patients at high cardiovascular (CV) risk, for example, benefit from a combination of aspirin, antihypertensive agents, lipid-lowering drugs, and possibly folic acid. As th...

journal_title：European heart journal

authors： Sleight P,Pouleur H,Zannad F

更新日期：2006-07-01 00:00:00

abstract：AIMS:The Tako-Tsubo cardiomyopathy (TTC) is characterized by a transient contractile dysfunction that has been assigned to excessive catecholamine levels after episodes of severe emotional or physical stress. Several studies have indicated that beta-adrenoceptor stimulation is associated with alteration in gene express...

journal_title：European heart journal

authors： Nef HM,Möllmann H,Troidl C,Kostin S,Voss S,Hilpert P,Behrens CB,Rolf A,Rixe J,Weber M,Hamm CW,Elsässer A

更新日期：2009-09-01 00:00:00

abstract：AIMS:To compare the precursor of atrial and brain natriuretic peptide (N-ANP, N-BNP), brain natriuretic peptide (BNP), big endothelin-1, the 6-min walk test and the Minnesota Living with Heart Failure Questionnaire (LHFQ) with regard to short-term outcome in an ambulatory heart failure population. METHODS AND RESULTS:...

journal_title：European heart journal

authors： Hülsmann M,Berger R,Sturm B,Bojic A,Woloszczuk W,Bergler-Klein J,Pacher R

更新日期：2002-06-01 00:00:00

abstract：:A time-domain signal-averaged ECG was performed in 52 patients with arrhythmogenic right ventricular dysplasia (ARVD) proven by angiography, in 45 control subjects with normal hearts, and in 132 patients with various types of ventricular arrhythmias and no evidence of cardiac disease during routine cardiac examination...

journal_title：European heart journal

authors： Leclercq JF,Coumel P

更新日期：1993-09-01 00:00:00

abstract：AIMS:Patients undergoing catheter ablation for atrial fibrillation (AF) often experience recurrent arrhythmias within the first few months post-ablation. We aimed to investigate whether short-term use of amiodarone to prevent early arrhythmias following radiofrequency ablation for AF could reduce later recurrence. MET...

journal_title：European heart journal

authors： Darkner S,Chen X,Hansen J,Pehrson S,Johannessen A,Nielsen JB,Svendsen JH

更新日期：2014-12-14 00:00:00

abstract：:The electrocardiographic patterns, observed during 24-h Holter monitoring, of 10 patients (mean age 35 +/- 22 years) with first and second degree A-V block due to dual A-V nodal pathways are reported. Recordings were selected according to the presence of: sudden and persistent prolongation of the PR interval: sudden n...

journal_title：European heart journal

authors： Di Biase M,Tritto M,Sabato G,Pitzalis MV,Rizzon P

更新日期：1991-03-01 00:00:00

abstract：AIMS:In patients with ischaemic left ventricular (LV) dysfunction and viable myocardium, revascularization improves systolic function. Diastolic dysfunction is also present in such patients; however, whether revascularization improves diastolic function also is largely unknown. METHODS:Twenty-six patients with chronic...

journal_title：European heart journal

authors： Carluccio E,Biagioli P,Alunni G,Murrone A,Leonelli V,Pantano P,Vincenti G,Giombolini C,Ragni T,Reboldi G,Gentile F,Ambrosio G

更新日期：2009-06-01 00:00:00

abstract：:The left atrial appendage (LAA) is the main source of thromboembolism in patients with non-valvular atrial fibrillation (AF). As such, the LAA can be the target of specific occluding device therapies. Optimal management of patients with AF includes a comprehensive knowledge of the many aspects related to LAA structure...

journal_title：European heart journal

authors： Patti G,Pengo V,Marcucci R,Cirillo P,Renda G,Santilli F,Calabrò P,De Caterina AR,Cavallari I,Ricottini E,Parato VM,Zoppellaro G,Di Gioia G,Sedati P,Cicchitti V,Davì G,Golia E,Pariggiano I,Simeone P,Abbate R,Prisco

更新日期：2017-03-21 00:00:00

abstract：:We describe a patient with a large intramyocardial hydatid cyst lying in the postero-lateral segment of the left ventricle near the atrioventricular groove level which ruptured into the pericardial sac, resulting in cardiac tamponade. Cross-sectional echocardiographic examination from a modified four-chamber apical vi...

journal_title：European heart journal

authors： De Martini M,Nador F,Binda A,Arpesani A,Odero A,Lotto A

更新日期：1988-07-01 00:00:00

abstract：AIMS:Carotid intima-media thickness (CIMT) and plaque information can improve coronary heart disease (CHD) risk prediction when added to traditional risk factors (TRF). However, obtaining adequate images of all carotid artery segments (A-CIMT) may be difficult. Of A-CIMT, the common carotid artery intima-media thicknes...

journal_title：European heart journal

authors： Nambi V,Chambless L,He M,Folsom AR,Mosley T,Boerwinkle E,Ballantyne CM

更新日期：2012-01-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of nadolol in modifying the standard deviation of RR intervals (SDRR) and the coefficient of variance (CV) in 47 patients characterized by symptomatic, frequent (> 30 h-1) and reproducible premature ventricular contractions (PVCs). Sixteen patients had suffered a previo...

journal_title：European heart journal

authors： Pitzalis MV,Mastropasqua F,Massari F,Totaro P,Passantino A,Rizzon P

更新日期：1995-02-01 00:00:00

abstract：:ST segment monitoring by Holter ECG was conducted in 80 consecutive patients 2-4 weeks before aortocoronary bypass surgery and three weeks and six months after surgery. Preoperatively, all patients were under maximal medical therapy. In 31 out of 80 patients medical therapy could be stopped and thus 24-h ST monitoring...

journal_title：European heart journal

authors： Droste C,Lemmen S,Nitsche R,Betz P,Birnbaum D,Roskamm H

更新日期：1988-12-01 00:00:00

abstract：:The study of 'atrial vulnerability' is often clinically indicated but it requires the use of invasive intracardiac stimulation. The purpose of the study was to assess the use of oesophageal pacing in the evaluation of atrial tachyarrhythmias (ATA). Fifty-five patients with documented ATA (group I) and 60 without (grou...

journal_title：European heart journal

authors： Brembilla-Perrot B

更新日期：1994-08-01 00:00:00

abstract：AIMS:Growing data suggest that antibiotic exposure is associated with a long-lasting alteration in gut microbiota, and may be related to subsequent cardiovascular disease (CVD). We investigated associations of life-stage and duration of antibiotic exposure during adulthood with subsequent CVD events. METHODS AND RESUL...

journal_title：European heart journal

authors： Heianza Y,Zheng Y,Ma W,Rimm EB,Albert CM,Hu FB,Rexrode KM,Manson JE,Qi L

更新日期：2019-12-14 00:00:00