Clinical and diagnostic utility of arbutamine for cardiovascular stress testing during echocardiographic monitoring.

Abstract:

:Arbutamine (Gensia, Inc., San Diego, CA) is a newly-developed sympathomimetic agent specifically designed for cardiovascular stress testing. It has been successfully used for the detection of coronary artery disease in conjunction with electrocardiography, echocardiographic and radionuclide techniques. Arbutamine increases heart rate and contractility, thus provoking ischaemia in a manner analogous to that of physical exercise. Ischaemia becomes manifest by reproduction of typical angina, diagnostic electrocardiographic changes, the development of a wall motion abnormality on two-dimensional echocardiography or of a perfusion defect on thallium scintigraphy. Thus far in clinical trials it has shown an acceptable side-effect profile and a level of diagnostic accuracy for the detection of patients with coronary disease equivalent to or exceeding that seen with physical exercise.

journal_name

Eur Heart J

journal_title

European heart journal

authors

Armstrong WF,Bach DS

doi

10.1093/eurheartj/16.suppl_m.24

subject

Has Abstract

pub_date

1995-11-01 00:00:00

pages

24-7

eissn

0195-668X

issn

1522-9645

journal_volume

16 Suppl M

pub_type

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