One-year clinical outcomes of protected and unprotected left main coronary artery stenting.

Abstract:

AIMS:To evaluate outcomes for left main coronary artery (LMCA) stenting and compare results between protected (left coronary grafted) and unprotected LMCA stenting in the current bare-metal stent era. METHODS:We reviewed outcomes among 142 consecutive patients who underwent protected or unprotected LMCA stenting since 1997. All-cause mortality, myocardial infarction (MI), target-lesion revascularization (TLR), and the combined major adverse clinical event (MACE) rates at one year were computed. RESULTS:Ninety-nine patients (70%) underwent protected and 43 patients (30%) underwent unprotected LMCA stenting. In the unprotected group, 86% were considered poor surgical candidates. Survival at one year was 88% for all patients, TLR 20%, and MACE 32%. At one year, survival was reduced in the unprotected group (72% vs. 95%, P<0.001) and MACE was increased in the unprotected patients (49% vs. 25%, P=0.005). CONCLUSIONS:In the current era, stenting for both protected and unprotected LMCA disease is still associated with high long-term mortality and MACE rates. Stenting for unprotected LMCA disease in a high-risk population should only be considered in the absence of other revascularization options. Further studies are needed to evaluate the role of stenting for unprotected LMCA disease.

journal_name

Eur Heart J

journal_title

European heart journal

authors

Kelley MP,Klugherz BD,Hashemi SM,Meneveau NF,Johnston JM,Matthai WH Jr,Banka VS,Herrmann HC,Hirshfeld JW Jr,Kimmel SE,Kolansky DM,Horwitz PA,Schiele F,Bassand JP,Wilensky RL

doi

10.1016/s0195-668x(03)00314-2

subject

Has Abstract

pub_date

2003-09-01 00:00:00

pages

1554-9

issue

17

eissn

0195-668X

issn

1522-9645

pii

S0195668X03003142

journal_volume

24

pub_type

杂志文章
  • Relation between serum N-terminal pro-brain natriuretic peptide and prognosis in patients with hypertrophic cardiomyopathy.

    abstract:AIMS:To determine the relation between serum concentrations of N-terminal pro-brain natriuretic peptide (NT-proBNP) and prognosis in patients with hypertrophic cardiomyopathy (HCM). METHODS AND RESULTS:In total, 847 patients (53 ± 15 years; 67% male) with HCM (28% with left ventricular outflow tract obstruction ≥ 30 m...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/eht070

    authors: Coats CJ,Gallagher MJ,Foley M,O'Mahony C,Critoph C,Gimeno J,Dawnay A,McKenna WJ,Elliott PM

    更新日期:2013-08-01 00:00:00

  • Anti-ischaemic intervention with verapamil in patients recovering from acute myocardial infarction.

    abstract::The present review discusses the prognostic significance of post-infarction angina pectoris, and the significance of post-infarction intervention with verapamil on the prevalence of post-infarction ischaemia and prognosis. Angina pectoris during the first month after acute myocardial infarction (AMI) was found to be a...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/16.suppl_h.13

    authors: Jespersen CM

    更新日期:1995-08-01 00:00:00

  • Oxidative modification of tropomyosin and myocardial dysfunction following coronary microembolization.

    abstract:AIMS:We addressed a potential mechanism of myocardial dysfunction following coronary microembolization at the level of myofibrillar proteins. METHODS AND RESULTS:Anaesthetized pigs underwent intracoronary infusion of microspheres. After 6 h, the microembolized areas (MEA) had decreased systolic wall thickening to 38 +...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehi751

    authors: Canton M,Skyschally A,Menabò R,Boengler K,Gres P,Schulz R,Haude M,Erbel R,Di Lisa F,Heusch G

    更新日期:2006-04-01 00:00:00

  • New diagnostic criteria for infective endocarditis. A study of sensitivity and specificity.

    abstract:OBJECTIVE:The purpose of this study was to determine the sensitivity and specificity of new criteria proposed by Duke University for case definition of infective endocarditis as compared to the previously accepted Von Reyn criteria. PATIENTS:A total of 143 consecutive suspected cases of infective endocarditis in 137 f...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a015411

    authors: Cecchi E,Parrini I,Chinaglia A,Pomari F,Brusasco G,Bobbio M,Trinchero R,Brusca A

    更新日期:1997-07-01 00:00:00

  • Mitral valve repair for mitral insufficiency.

    abstract::Degenerative mitral valve disease has become the major cause of mitral regurgitation in North America; it is incumbent on surgeons to know repair techniques and to document their results. Fortunately, improvements in myocardial protection have been concurrent with the evolution of mitral valve repair in our country. T...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/12.suppl_b.30

    authors: Loop FD,Cosgrove DM,Stewart WJ

    更新日期:1991-07-01 00:00:00

  • Ischaemic threshold and haemodynamic changes during angina at rest in patients with unstable angina.

    abstract::To examine whether increases in heart rate might be a common trigger of angina at rest, changes in heart rate, blood pressure and rate-pressure product during pain were compared with the ischaemic threshold (heart rate with ST segment shift > = 1 mm), determined by atrial pacing, in 272 patients with unstable angina. ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/14.9.1170

    authors: Figueras J,Lidón RM,Serés L

    更新日期:1993-09-01 00:00:00

  • Midlife blood pressure is associated with the severity of white matter hyperintensities: analysis of the UK Biobank cohort study.

    abstract:AIMS:White matter hyperintensities (WMH) progress with age and hypertension, but the key period of exposure to elevated blood pressure (BP), and the relative role of systolic BP (SBP) vs. diastolic BP (DBP), remains unclear. This study aims to determine the relationship between WMH and concurrent vs. past BP. METHODS ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehaa756

    authors: Wartolowska KA,Webb AJS

    更新日期:2020-11-26 00:00:00

  • Early remodelling of the left ventricle in patients with myocardial infarction.

    abstract::Sequential alterations of left ventricular volumes and haemodynamics were studied in 29 patients between 4 days and 4 weeks after myocardial infarction. Left ventricular volume was determined by single photon emission computerized tomography (SPECT), infarct size by creatine kinase (CK) analysis, angiography and thall...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/11.suppl_b.139

    authors: Gaudron P,Eilles C,Ertl G,Kochsiek K

    更新日期:1990-04-01 00:00:00

  • Risk of dementia in stroke-free patients diagnosed with atrial fibrillation: data from a community-based cohort.

    abstract:AIMS:To estimate the incidence of dementia after the first atrial fibrillation (AF), and its impact on survival in a community-based cohort. METHODS AND RESULTS:Olmsted County, Minnesota adult residents diagnosed with first AF during 1986-2000 were identified, and followed until 2004. The primary outcome was new detec...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehm012

    authors: Miyasaka Y,Barnes ME,Petersen RC,Cha SS,Bailey KR,Gersh BJ,Casaclang-Verzosa G,Abhayaratna WP,Seward JB,Iwasaka T,Tsang TS

    更新日期:2007-08-01 00:00:00

  • Fascicular tachycardia sensitive to calcium antagonists.

    abstract::Five patients with recurrent tachycardias exhibiting right bundle branch block with left axis deviation were referred for investigation. In each case, a supraventricular mechanism was suspected. During sinus rhythm the QRS morphology and axis (-10 to +60 degrees) and HV intervals were normal. Tachycardia was initiated...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a061589

    authors: Ward DE,Nathan AW,Camm AJ

    更新日期:1984-11-01 00:00:00

  • Pyrimidine nucleotide metabolism in cardiac hypertrophy.

    abstract::Cardiac hypertrophy was induced in rats either by isoprenaline treatment or by experimental abdominal aortic stenosis. In both models, the UTP content increased in the hypertrophying heart, while the ATP level remained depressed. The rate of net synthesis of uracil nucleotides, estimated by phosphate incorporation int...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/5.suppl_f.155

    authors: Rossi A,Aussedat J,Olivarès J,Ray A,Verdys M

    更新日期:1984-12-01 00:00:00

  • Prognosis and treatment of atrial fibrillation patients by European cardiologists: one year follow-up of the EURObservational Research Programme-Atrial Fibrillation General Registry Pilot Phase (EORP-AF Pilot registry).

    abstract:BACKGROUND:The EURObservational Research Programme-Atrial Fibrillation General Registry Pilot Phase (EORP-AF Pilot) provides systematic collection of contemporary data regarding the management and treatment of 3119 subjects with AF from 9 member European Society of Cardiology (ESC) countries. In this analysis, we repor...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehu374

    authors: Lip GY,Laroche C,Ioachim PM,Rasmussen LH,Vitali-Serdoz L,Petrescu L,Darabantiu D,Crijns HJ,Kirchhof P,Vardas P,Tavazzi L,Maggioni AP,Boriani G

    更新日期:2014-12-14 00:00:00

  • Effect of breathing oxygen-enriched air on exercise performance in patients with precapillary pulmonary hypertension: randomized, sham-controlled cross-over trial.

    abstract:Aims:The purpose of the current trial was to test the hypothesis that breathing oxygen-enriched air increases exercise performance of patients with pulmonary arterial or chronic thrombo-embolic pulmonary hypertension (PAH/CTEPH) and to investigate involved mechanisms. Methods and results:Twenty-two patients with PAH/C...

    journal_title:European heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/eurheartj/ehx099

    authors: Ulrich S,Hasler ED,Saxer S,Furian M,Müller-Mottet S,Keusch S,Bloch KE

    更新日期:2017-04-14 00:00:00

  • The impact of eplerenone at different levels of risk in patients with systolic heart failure and mild symptoms: insight from a novel risk score for prognosis derived from the EMPHASIS-HF trial.

    abstract:AIMS:Our objective was to create a simple prognostic risk score for patients with systolic heart failure and mild symptoms. We then assessed the efficacy of eplerenone across different categories of risk. METHODS AND RESULTS:The Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure trial (EMP...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/eht247

    authors: Collier TJ,Pocock SJ,McMurray JJ,Zannad F,Krum H,van Veldhuisen DJ,Swedberg K,Shi H,Vincent J,Pitt B

    更新日期:2013-09-01 00:00:00

  • Effects of simvastatin on plasma lipid, lipoprotein and apolipoprotein concentrations in hypercholesterolaemia.

    abstract::The effect of 24 weeks of treatment with simvastatin, a new HMG coenzyme A reductase inhibitor (dosages of 20 and 40 mg day-1) on serum lipid, lipoprotein and apolipoprotein A-I and B concentrations as well as safety parameters and subjective side effects were studied in 11 patients with familial (FH) and 10 patients ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a062541

    authors: Mölgaard J,von Schenck H,Olsson AG

    更新日期:1988-05-01 00:00:00

  • Left atrial appendage closure: a percutaneous transcatheter approach for stroke prevention in atrial fibrillation.

    abstract::Atrial fibrillation is a frequent cause of stroke; in the elderly, more than 20% of strokes are attributed to this common arrhythmia. Anticoagulation with warfarin reduces the risk of stroke by ∼60%; however, a large proportion of patients with atrial fibrillation do not receive this treatment because of relative/abso...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/ehr393

    authors: Landmesser U,Holmes DR Jr

    更新日期:2012-03-01 00:00:00

  • The value of exercise-induced U-wave inversion on ECG chest wall mapping in the identification of individual coronary arterial lesions.

    abstract::Exercise-induced U-wave inversion on chest wall mapping was compared with coronary arteriographic findings in 160 consecutive patients who presented with chest pain suggestive of ischaemic heart disease. ECG recordings were made from 16 points on the chest wall before, during and after exercise. None of the 27 patient...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a061883

    authors: Salmasi AM,Salmasi SN,Nicolaides AN,Vecht RJ,Hendry WG,Kidner PH,Besterman EM

    更新日期:1985-05-01 00:00:00

  • Myocardial infarction and the myocyte IGF1 autocrine system.

    abstract::To determine the effects of acute myocardial infarction on the extent and distribution of mural stress on surviving myocardial tissue, coronary artery occlusion was surgically produced in rats. Following haemodynamic measurements in vivo, the characteristics of cardiac anatomy were determined and found to consist of a...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/16.suppl_n.37

    authors: Anversa P,Reiss K,Kajstura J,Cheng W,Li P,Sonnenblick EH,Olivetti G

    更新日期:1995-12-01 00:00:00

  • Exercise and the heart: the good, the bad, and the ugly.

    abstract::The benefits of exercise are irrefutable. Individuals engaging in regular exercise have a favourable cardiovascular risk profile for coronary artery disease and reduce their risk of myocardial infarction by 50%. Exercise promotes longevity of life, reduces the risk of some malignancies, retards the onset of dementia, ...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/ehv090

    authors: Sharma S,Merghani A,Mont L

    更新日期:2015-06-14 00:00:00

  • Quantitative relationship between resting heart rate reduction and magnitude of clinical benefits in post-myocardial infarction: a meta-regression of randomized clinical trials.

    abstract:AIMS:The impact on mortality outcomes of beta-blockers and calcium blockers in post-myocardial infarction (MI) has been suggested to be related to resting heart rate (HR) reduction. A meta-regression of randomized clinical trials was carried out to assess this relationship using weighted meta-regression of logarithm of...

    journal_title:European heart journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.1093/eurheartj/ehm489

    authors: Cucherat M

    更新日期:2007-12-01 00:00:00

  • The neurohormonal basis of pulmonary hypertension in heart failure with preserved ejection fraction.

    abstract:AIMS:Pulmonary hypertension (PH) represents an important phenotype among the broader spectrum of patients with heart failure with preserved ejection fraction (HFpEF), but its mechanistic basis remains unclear. We hypothesized that activation of endothelin and adrenomedullin, two counterregulatory pathways important in ...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章

    doi:10.1093/eurheartj/ehz626

    authors: Obokata M,Kane GC,Reddy YNV,Melenovsky V,Olson TP,Jarolim P,Borlaug BA

    更新日期:2019-12-01 00:00:00

  • International variation in invasive care of the elderly with acute coronary syndromes.

    abstract:AIMS:To explore variations in invasive care of the elderly with acute coronary syndromes across international practice. METHODS AND RESULTS:Using combined populations from the SYMPHONY and 2nd SYMPHONY trials, we describe 30-day cardiac catheterization in elderly (> or = 75 years; n = 1794) vs. younger patients (< 75 ...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehl067

    authors: Alexander KP,Newby LK,Bhapkar MV,White HD,Hochman JS,Pfisterer ME,Moliterno DJ,Peterson ED,Van de Werf F,Armstrong PW,Califf RM,Symphony and 2nd Symphony Investigators.

    更新日期:2006-07-01 00:00:00

  • Lesion morphology assessed by pre-interventional intravascular ultrasound does not predict the incidence of severe coronary artery dissections.

    abstract:AIMS:Coronary artery dissections are common findings following percutaneous transluminal coronary angioplasty and occur with an incidence of approximately 20% to 40%. The purpose of this study was to evaluate the impact of intravascular ultrasound for the prediction of severe dissections by pre-interventional analysis ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1053/euhj.1997.0799

    authors: Athanasiadis A,Haase KK,Wullen B,Treusch AW,Mahrholdt H,Voelker W,Baumbach A,Oberhoff M,Karsch KR

    更新日期:1998-06-01 00:00:00

  • Detection of prosthetic valve thrombosis using 111indium platelet imaging.

    abstract::The diagnosis of prosthetic valve thrombosis (PVT) may be difficult in cases without valve obstruction. The aim of this study was to evaluate the diagnostic accuracy of 111indium-labelled autologous platelet imaging in the detection of PVT. We studied 41 patients with 45 prostheses, mechanical (37) or biological (8), ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a059721

    authors: Acar J,Vahanian A,Dorent R,Fauchet M,Mundler O,Michel PL,Roger V,Cormier B

    更新日期:1990-05-01 00:00:00

  • Local slow potential preceding the surface QRS complex detected at the subvalvular mitral annulus in patients with a left-sided concealed accessory pathway. Incidence, electrophysiological characteristics and the possible mechanism, with demonstration of

    abstract:AIM:We sought to evaluate the incidence and electrophysiological features of the local slow potential preceding the surface QRS complex (pre-QRS potential) which was detected more frequently at successful sites of catheter ablation of left parietal concealed accessory pathways, than at unsuccessful sites. METHODS AND ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1053/euhj.1999.1688

    authors: Miyauchi Y,Kobayashi Y,Ino T,Atarashi H

    更新日期:1999-12-01 00:00:00

  • The arterial baroreflex and the cardiopulmonary reflex in borderline hypertension.

    abstract::An elevation of the cardiopulmonary baroreflex control of the forearm vascular resistances due to an impairment of the arterial baroreflex has been postulated in borderline hypertension. The purpose of the study is to verify this hypothesis. The arterial baroreflex sensitivity, measured by the phenylephrine method is ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/4.suppl_g.41

    authors: Bovy P,Juchmes J,Fossion A

    更新日期:1983-11-01 00:00:00

  • Central nervous system function after cardiopulmonary bypass.

    abstract::In a prospective study, an elderly group of patients (n = 63, 47 male, 16 female, age 40-65 years) was examined before and after open-heart surgery under cardiopulmonary bypass: postoperatively, 19 patients (30%) showed no clinical neuropsychiatric symptoms, whereas in 35 patients (56%) mild or transient neurological ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/14.7.885

    authors: Zeitlhofer J,Asenbaum S,Spiss C,Wimmer A,Mayr N,Wolner E,Deecke L

    更新日期:1993-07-01 00:00:00

  • Clinical relevance of vegetation localization by transoesophageal echocardiography in infective endocarditis.

    abstract::Infective endocarditis is associated with significant morbidity and mortality, with valvular destruction and congestive heart failure being more common in patients with echocardiographically discernible vegetations. The transoesophageal approach affords consistently high quality images with excellent structural resolu...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a060195

    authors: Rohmann S,Erbel R,Görge G,Makowski T,Mohr-Kahaly S,Nixdorff U,Drexler M,Meyer J

    更新日期:1992-04-01 00:00:00

  • The QRS score: a promising new exercise score for detecting coronary artery disease based on exercise-induced changes of Q-, R- and S-waves: a relationship with myocardial ischaemia.

    abstract:BACKGROUND:Recently, a new exercise test criterion diagnosing coronary artery disease was proposed, based on a composite of changes in Q-, R- and S-waves: the QRS score. We compared this new criterion with conventional ST-segment depression and other compositions of Q-, R- and S-wave changes in patients and normals and...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a014936

    authors: van Campen CM,Visser FC,Visser CA

    更新日期:1996-05-01 00:00:00

  • Fasting plasma glucose in non-diabetic participants and the risk for incident cardiovascular events, diabetes, and mortality: results from WOSCOPS 15-year follow-up.

    abstract:AIMS:The evidence base for fasting plasma glucose (FPG) in the non-diabetic range as a risk factor for cardiovascular disease (CVD) is inconclusive. We investigated this question in the West of Scotland Coronary Prevention Study (WOSCOPS). METHODS AND RESULTS:In WOSCOPS, we related FPG in 6447 men (mean age 55 years) ...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/ehq095

    authors: Preiss D,Welsh P,Murray HM,Shepherd J,Packard C,Macfarlane P,Cobbe S,Ford I,Sattar N

    更新日期:2010-05-01 00:00:00