Personality traits and heart rate variability predict long-term cardiac mortality after myocardial infarction.

Abstract:

AIMS:To investigate personality traits and sympatho-vagal modulation of heart rate variability (HRV) during acute myocardial infarction (AMI), assessing their relationships and their long-term prognostic value. METHODS AND RESULTS:Psychological traits and 24 h HRV were prospectively investigated in 246 patients at discharge of an AMI. Patients were followed-up to 8 years for the occurrence of cardiac death and non-fatal reinfarction. Low coping and anxiety traits associated with reduced HRV characterized the study population. At univariate analysis, low emotional sensitivity and insecurity, relative tachycardia, reduced high frequency (HF), and low frequency power and pNN50 were predictive of cardiac death at 8-year follow-up. At multivariable analysis, low emotional sensitivity and low HF power remained predictive, with a relative risk of 4.18 (P=0.003) and 2.76 (P=0.007), respectively; also the type of infarction (Q vs. non-Q) and hospital length of stay were independent predictive variables. CONCLUSION:Anxiety and emotional sensitivity were significant predictors of 8-year cardiac mortality after AMI. Reduced HF power, a recognized marker of vagal withdrawal, increased the risk.

journal_name

Eur Heart J

journal_title

European heart journal

authors

Carpeggiani C,Emdin M,Bonaguidi F,Landi P,Michelassi C,Trivella MG,Macerata A,L'Abbate A

doi

10.1093/eurheartj/ehi252

subject

Has Abstract

pub_date

2005-08-01 00:00:00

pages

1612-7

issue

16

eissn

0195-668X

issn

1522-9645

pii

ehi252

journal_volume

26

pub_type

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