Abstract:
:Recent studies have illustrated that in addition to the well known risk factors, such as lipoproteins, smoking, hypertension, there are others that cause atherosclerosis and myocardial infarction. Our knowledge of atherosclerotic lesions has increased. We now know that atherosclerotic changes are due to inflammatory cell infiltration as well as to increases in migration of vascular smooth muscle cells. Endothelial cells play a major role in the pathology of vascular changes. In recent years a new risk factor for coronary artery disease has been discovered: chlamydia pneumonial infections. Herpes class viruses have also been associated with pathology of atherosclerotic lesions. Studies show that dental status and bacterial infections are also related to the risk of myocardial infarction. This review discusses the possible mechanisms of infection and inflammation and whether they are major or modifying risk factors for atherosclerosis and myocardial infarction.
journal_name
Eur Heart Jjournal_title
European heart journalauthors
Nieminen MS,Mattila K,Valtonen Vsubject
Has Abstractpub_date
1993-12-01 00:00:00pages
12-6eissn
0195-668Xissn
1522-9645journal_volume
14 Suppl Kpub_type
杂志文章,评审abstract:BACKGROUND:There is much interest in reported associations between serum C-reactive protein and incident ischaemic heart disease. It is uncertain what this association represents. We aimed to assess the effect of confounding from a number of different sources in the Caerphilly Prospective Heart Disease Study and in par...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1053/euhj.1999.1982
更新日期:2000-10-01 00:00:00
abstract:AIMS:In Belgium, general practitioners (GPs) mainly manage oral anticoagulation therapy. To improve the quality of oral anticoagulation management by GPs and to compare different models and interventions, a randomized clinical trial was performed. METHODS AND RESULTS:Stratified randomization divided 66 GP-practices in...
journal_title:European heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1093/eurheartj/ehi327
更新日期:2005-10-01 00:00:00
abstract:AIMS:To determine the diagnostic utility of circulating angiopoietin-1 (Ang-1) and its antagonist angiopoietin-2 (Ang-2) as potential biomarkers of disease severity or response to treatment in idiopathic pulmonary arterial hypertension (IPAH). Imbalances in angiogenic factors including vascular endothelial cell growth ...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehq226
更新日期:2010-09-01 00:00:00
abstract::Haemodynamic effects of pharmacological doses of insulin during acute ischaemic heart failure were studied in 8 dogs. Severe depression of left ventricular function was induced by the injection of 50 micron plastic microspheres into the left main coronary artery. This was demonstrated by a significant increase in left...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a061885
更新日期:1985-05-01 00:00:00
abstract:BACKGROUND:Percutaneous mitral valvuloplasty with the Inoue balloon is conventionally performed with double vascular access: arterial and venous. However, in patients with a good echogenic window it may be performed with venous access only and the procedure monitored by 2D-echocardiography and colour flow mapping. This...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1053/euhj.1997.0803
更新日期:1998-04-01 00:00:00
abstract::The Belgian Heart Disease Prevention Project was a controlled, randomized multifactorial intervention trial in middle-aged men which lasted 6 years. Significant net differences between intervention and control groups were observed in change in risk profile, in total mortality and in CHD incidence. The net difference i...
journal_title:European heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/oxfordjournals.eurheartj.a062491
更新日期:1988-03-01 00:00:00
abstract::The acute electrophysiologic effects of clinical doses of procainamide, lidocaine, metoprolol, digoxin and atropine upon the conduction of ventricular premature beats, were studied in 48 healthy volunteers. The conduction time of the first premature beat, induced 1 ms after the ventricular effective refractory period ...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a061755
更新日期:1985-01-01 00:00:00
abstract:Aims:Vascular ageing is characterized by arterial stiffening, dilation, and arterial wall thickening. We investigated the extent to which these changes are related and their heritability during 5 year follow-up in the Twins UK cohort. Methods and results:Carotid-femoral pulse wave velocity (PWVcf), carotid diameter, c...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehy165
更新日期:2018-06-21 00:00:00
abstract:AIMS:Morphological characteristics of non-significant coronary plaques (NSCPs) that develop rapid progression have not been fully elucidated. The aim of this study was to clarify the morphological characteristics of NSCPs in patients with coronary artery disease (CAD) using intravascular optical coherence tomography (O...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehr284
更新日期:2012-01-01 00:00:00
abstract:AIMS:To evaluate outcomes for left main coronary artery (LMCA) stenting and compare results between protected (left coronary grafted) and unprotected LMCA stenting in the current bare-metal stent era. METHODS:We reviewed outcomes among 142 consecutive patients who underwent protected or unprotected LMCA stenting since...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1016/s0195-668x(03)00314-2
更新日期:2003-09-01 00:00:00
abstract::Atrial fibrillation (AF) and chronic heart failure (CHF) are two major and even growing cardiovascular conditions that often coexist. However, few data are available to guide treatment of AF in patients with CHF. This review summarizes current literature concerning the following topics: (i) prognostic relevance of AF ...
journal_title:European heart journal
pub_type: 杂志文章,评审
doi:10.1093/eurheartj/ehm341
更新日期:2007-11-01 00:00:00
abstract::A new European Heart Journal, Cardiovascular Pharmacotherapy, was launched at the ESC Congress 2014 in Barcelona and begins publication in February 2014. ...
journal_title:European heart journal
pub_type: 新闻
doi:
更新日期:2014-09-07 00:00:00
abstract::Nitric oxide inhalation in myocardial infarction patients sends mixed messages, but may offer some benefit. ...
journal_title:European heart journal
pub_type: 新闻
doi:
更新日期:2015-05-14 00:00:00
abstract:AIMS:Although dilated cardiomyopathy is the most frequent form of cardiomyopathy, its aetiology is still poorly understood. In about 20-30% of cases the disease is familial with a large predominance of autosomal dominant transmission. Ten different chromosomal loci have been described for autosomal dominant forms of di...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1053/euhj.2000.2245
更新日期:2000-11-01 00:00:00
abstract:AIM:Previous studies have reported lifestyle and risk factor deterioration following completion of a cardiac rehabilitation program (CRP). We report the results of a one-year Extensive Lifestyle Management Intervention (ELMI) aimed at preventing these adverse changes. METHODS AND RESULTS:A total of 302 men and women w...
journal_title:European heart journal
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ehj.2003.08.015
更新日期:2003-11-01 00:00:00
abstract::In isolated atherosclerotic human coronary arteries endothelium-dependent vascular relaxation is abolished with acetylcholine whereas another EDRF-dependent vasodilator, substance P, still produces significant relaxation. To study further these in vitro findings, graded doses of acetylcholine and substance P, which pr...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/10.suppl_f.44
更新日期:1989-11-01 00:00:00
abstract::Transthoracic echocardiography and continuous wave Doppler were prospectively performed in 132 out-patients with suspicion of pulmonary embolism, and who had no previous history of severe cardiac or pulmonary disease. Bedside echocardiography determined diagnosis other than pulmonary embolism in 55 patients. Further s...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a014946
更新日期:1996-05-01 00:00:00
abstract:AIMS:N-terminal pro-brain natriuretic peptide (NT-proBNP) levels predict outcomes in ST-elevation myocardial infarction patients treated with fibrinolysis or primary percutaneous coronary intervention (PCI). However, its role in facilitated PCI has not yet been assessed; it may be a tool to evaluate the lower event rat...
journal_title:European heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1093/eurheartj/ehp246
更新日期:2009-09-01 00:00:00
abstract::The haemodynamic effects of intravenous frusemide (1 mg/kg) were studied in 22 male patients with left ventricular failure following acute myocardial infarction. Radiographic pulmonary oedema was present in all patients and their average left heart filling pressure was 20 mmHg. Bolus injection of the drug was followed...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/oxfordjournals.eurheartj.a061382
更新日期:1983-10-01 00:00:00
abstract:AIMS:To evaluate the effects of simvastatin only or combined with continuous hormone replacement therapy on the serum lipid profile in hypercholesterolaemic post-menopausal women. METHODS AND RESULTS:One hundred hypercholesterolaemic post-menopausal women were given either simvastatin 10 mg daily together with oestrog...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1053/euhj.1999.1582
更新日期:2000-02-01 00:00:00
abstract:Aims:Optimal blood pressure for prevention of cardiovascular (CV) events in patients with Type 2 diabetes mellitus (T2DM) remains uncertain and there is concern for increased risk with low diastolic blood pressure (DBP). This study analysed the association between blood pressure and CV outcomes in high-risk patients wi...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehx809
更新日期:2018-06-21 00:00:00
abstract:BACKGROUND:The calculation of valve resistance (R) rather than aortic valve area (AVA) has been proposed for the assessment of aortic stenosis (AS), based on the claim that it is less flow-dependent. Even more importantly, valve resistance has been reported to distinguish between truly severe and "pseudosevere" AS in p...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1016/j.ehj.2004.02.011
更新日期:2004-05-01 00:00:00
abstract::The benefits of exercise are irrefutable. Individuals engaging in regular exercise have a favourable cardiovascular risk profile for coronary artery disease and reduce their risk of myocardial infarction by 50%. Exercise promotes longevity of life, reduces the risk of some malignancies, retards the onset of dementia, ...
journal_title:European heart journal
pub_type: 杂志文章,评审
doi:10.1093/eurheartj/ehv090
更新日期:2015-06-14 00:00:00
abstract::In 2008, The ESC Working Group on Myocardial and Pericardial Diseases proposed an updated classification of cardiomyopathies based on morphological and functional phenotypes and subcategories of familial/genetic and non-familial/non-genetic disease. In this position statement, we propose a framework for the clinical a...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehs397
更新日期:2013-05-01 00:00:00
abstract:AIMS:Patients with pulmonary hypertension (PHT) are often excluded from surgical therapies for tricuspid regurgitation (TR). Transcatheter tricuspid valve repair (TTVR) with the MitraClip™ technique is a novel treatment option for these patients. We aimed to assess the role of PHT in severe TR and its implications for ...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehaa138
更新日期:2020-08-01 00:00:00
abstract::Although the number of individuals reaching 80 who are considered to be healthy is increasing, the very elderly are likely to have long-term conditions, to report symptoms and/or be taking at least one regular medication. The impact of antihypertensive treatment has to be taken into account in this context. The treatm...
journal_title:European heart journal
pub_type: 杂志文章,评审
doi:10.1093/eurheartj/eht464
更新日期:2014-07-01 00:00:00
abstract:AIMS:Non-vitamin K antagonist oral anticoagulants (NOACs) require dose reductions according to patient or clinical factors for patients with atrial fibrillation (AF). In this meta-analysis, we aimed to assess outcomes with reduced-dose NOACs when given as pre-specified in pivotal trials. METHODS AND RESULTS:Aggregated...
journal_title:European heart journal
pub_type: 杂志文章,meta分析
doi:10.1093/eurheartj/ehy802
更新日期:2019-05-14 00:00:00
abstract:AIMS:To assess the effect of experimentally induced atrial fibrillation on coronary flow in humans. METHODS AND RESULTS:In 16 patients (10 men, mean age 43+/-13 years) with normal coronary vessels, baseline and hyperaemic blood pressure and Doppler phasic coronary flow velocity were measured, using a 0.014 inch intrac...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1053/euhj.2001.2894
更新日期:2002-05-01 00:00:00
abstract::We have previously shown that transdermal nitroglycerin may induce an increase in the activity of the adrenergic and the renin-angiotensin-aldosterone systems (SRAA) in patients with chronic stable angina pectoris (SA); when the activation of these systems is more pronounced, the antianginal effect of this drug seems ...
journal_title:European heart journal
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1093/eurheartj/14.12.1701
更新日期:1993-12-01 00:00:00
abstract::This study describes the clinical profile and prognosis of elderly patients not eligible for predischarge exercise testing. The database consisted of 133 patients 55-64 years of age, and 111 patients older than 64 years of age who survived an acute myocardial infarction. Follow-up was one year. In the younger age grou...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/5.suppl_e.97
更新日期:1984-11-01 00:00:00