The beta-adrenergic receptor-adenylate cyclase complex as a target for therapeutic intervention in heart failure.

abstract：:Both epidemiological studies and intervention trials support an important role of diet in reducing the risk of a variety of chronic diseases, including cardiovascular disease, and overall mortality. We discuss available evidence indicating that the generation of a pro-inflammatory milieu might be one mechanism through...

journal_title：European heart journal

authors： Esposito K,Giugliano D

更新日期：2006-01-01 00:00:00

abstract：AIMS:There have been no large observational studies attempting to identify predictors of major bleeding in patients with acute coronary syndromes (ACS), particularly from a multinational perspective. The objective of our study was thus to develop a prediction rule for the identification of patients with ACS at higher r...

journal_title：European heart journal

authors： Moscucci M,Fox KA,Cannon CP,Klein W,López-Sendón J,Montalescot G,White K,Goldberg RJ

更新日期：2003-10-01 00:00:00

abstract：AIMS:This study compares the functional outcome and cardiorespiratory response to exercise, in patients who have undergone arterial switch for transposition of the great arteries, with normal controls and patients who have undergone atrial switch operation. METHODS AND RESULTS:Fifteen patients who had undergone arteri...

journal_title：European heart journal

authors： Reybrouck T,Eyskens B,Mertens L,Defoor J,Daenen W,Gewillig M

更新日期：2001-06-01 00:00:00

abstract：AIMS:Vascular endothelial growth factor-A (VEGF-A) is an angiogenic and vasoprotective molecule whose expression is modulated by hypoxia and inflammatory mediators. Here we have tested the hypothesis that plasma levels of VEGF-A are influenced by pre-existing coronary artery disease and by changes in circulating interl...

journal_title：European heart journal

authors： Cotton JM,Mathur A,Hong Y,Brown AS,Martin JF,Erusalimsky JD

更新日期：2002-06-01 00:00:00

abstract：AIMS:Prospective studies indicate that apolipoprotein measurements predict coronary heart disease (CHD) risk; however, evidence is conflicting, especially in the US. Our aim was to assess whether measurements of apolipoprotein B (apoB) and apolipoprotein A-I (apoA-I) can improve the ability to predict CHD death beyond ...

journal_title：European heart journal

authors： Sierra-Johnson J,Fisher RM,Romero-Corral A,Somers VK,Lopez-Jimenez F,Ohrvik J,Walldius G,Hellenius ML,Hamsten A

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Recent identification of mutations in the beta-myosin heavy chain gene (MYH7), a major responsible gene for HCM, has provided the opportunity to characterize genotype-phenotype correlation in HCM families. In this study we analysed the phenotypic expression of two beta-myosin heavy chain (beta MHC) mutations...

journal_title：European heart journal

authors： Marian AJ,Mares A Jr,Kelly DP,Yu QT,Abchee AB,Hill R,Roberts R

更新日期：1995-03-01 00:00:00

abstract：AIMS:Angiotensin-converting enzyme (ACE) inhibitors have been shown to reduce cardiovascular risk in different groups of patients. Whether these effects can be generalized to the broad group of patients with vascular disease is unknown. Therefore, we undertook a combined analysis using individual data from ADVANCE, EUR...

journal_title：European heart journal

authors： Brugts JJ,Ninomiya T,Boersma E,Remme WJ,Bertrand M,Ferrari R,Fox K,MacMahon S,Chalmers J,Simoons ML

更新日期：2009-06-01 00:00:00

abstract：:The reperfusion era has dramatically and irrevocably transformed the management of ST-segment elevation myocardial infarction (STEMI). For the patient treated with fibrinolysis as the initial reperfusion strategy, subsequent options which are the subject of some controversy and the focus of this review are (i) facilit...

journal_title：European heart journal

authors： Kiernan TJ,Ting HH,Gersh BJ

更新日期：2007-07-01 00:00:00

abstract：AIMS:Using a large, contemporary primary care population we aimed to provide absolute long-term risks of cardiovascular death (CVD) based on the QTc interval and to test whether the QTc interval is of value in risk prediction of CVD on an individual level. METHODS AND RESULTS:Digital electrocardiograms from 173 529 pr...

journal_title：European heart journal

authors： Nielsen JB,Graff C,Rasmussen PV,Pietersen A,Lind B,Olesen MS,Struijk JJ,Haunsø S,Svendsen JH,Køber L,Gerds TA,Holst AG

更新日期：2014-05-21 00:00:00

abstract：:The benefits of exercise are irrefutable. Individuals engaging in regular exercise have a favourable cardiovascular risk profile for coronary artery disease and reduce their risk of myocardial infarction by 50%. Exercise promotes longevity of life, reduces the risk of some malignancies, retards the onset of dementia, ...

journal_title：European heart journal

authors： Sharma S,Merghani A,Mont L

更新日期：2015-06-14 00:00:00

abstract：:One case of unruptured sinus of Valsalva aneurysm causing left coronary artery compression and lethal myocardial infarction in a 39-year old woman is described. In reviewing the literature, 15 previously published cases of sinus of Valsalva aneurysms disturbing coronary flow were found. It is concluded that the mechan...

journal_title：European heart journal

authors： Brandt J,Jögi P,Lührs C

更新日期：1985-12-01 00:00:00

abstract：AIMS:To evaluate the effect of thrombolysis on mortality and its causes in older patients with acute myocardial infarction (AMI). METHODS AND RESULTS:An analysis of 706 consecutive patients > or =75 years old with a first AMI enrolled in the PPRIMM75 registry showed that although there were important differences in ba...

journal_title：European heart journal

authors： Bueno H,Martínez-Sellés M,Pérez-David E,López-Palop R

更新日期：2005-09-01 00:00:00

abstract：:Intracoronary ultrasound was performed at diagnostic coronary angiography and 10 days later in a 45-year-old patient with a 3-day history of acute inferior myocardial infarction. Coronary angiography showed considerable stenosis (80%) in the distal right coronary artery (RCA) (pre the crux) and what appeared to be a d...

journal_title：European heart journal

authors： Ge J,Haude M,Görge G,Liu F,Erbel R

更新日期：1995-08-01 00:00:00

abstract：:Glycaemic control is an inadequate surrogate marker of cardiovascular event reduction in patients with type 2 diabetes. Clinical trials to date have been unsuccessful in identifying a therapeutic approach that addresses the underlying problem in diabetes (glycaemic control) and reduces cardiovascular risk. The potenti...

journal_title：European heart journal

authors： Zannad F,Stough WG,Pocock SJ,Sleight P,Cushman WC,Cleland JG,McMurray JJ,Lonn E,Geller NL,Wedel H,Abadie E,Alonso-Garcia A,Pitt B

更新日期：2012-05-01 00:00:00

abstract：AIMS:The Tako-Tsubo cardiomyopathy (TTC) is characterized by a transient contractile dysfunction that has been assigned to excessive catecholamine levels after episodes of severe emotional or physical stress. Several studies have indicated that beta-adrenoceptor stimulation is associated with alteration in gene express...

journal_title：European heart journal

authors： Nef HM,Möllmann H,Troidl C,Kostin S,Voss S,Hilpert P,Behrens CB,Rolf A,Rixe J,Weber M,Hamm CW,Elsässer A

更新日期：2009-09-01 00:00:00

abstract：AIMS:To investigate the efficacy and outcome of emergency percutaneous coronary interventions (PCI) in patients with stent thrombosis. METHODS AND RESULTS:Between 1995 and 2003, 6058 patients underwent bare-metal stent implantation, of which 95 (1.6%) patients suffered from stent thrombosis. The timing of stent thromb...

journal_title：European heart journal

authors： Wenaweser P,Rey C,Eberli FR,Togni M,Tüller D,Locher S,Remondino A,Seiler C,Hess OM,Meier B,Windecker S

更新日期：2005-06-01 00:00:00

abstract：AIMS:The aim is to compare the coronary risk chart published by the European Task Force for Prevention of Coronary Heart Disease and produced using a Framingham risk function, with a risk function derived from an Italian population study. METHODS AND RESULTS:Coronary risk function in this study was the result of longi...

journal_title：European heart journal

authors： Menotti A,Puddu PE,Lanti M

更新日期：2000-03-01 00:00:00

abstract：AIMS:Despite disparities in pathophysiology and disease manifestation between male and female patients with heart failure, studies focusing on sex differences in biomarkers are scarce. The purpose of this study was to assess sex-specific variation in clinical characteristics and biomarker levels to gain more understand...

journal_title：European heart journal

authors： Meyer S,van der Meer P,van Deursen VM,Jaarsma T,van Veldhuisen DJ,van der Wal MH,Hillege HL,Voors AA

更新日期：2013-08-01 00:00:00

abstract：AIMS:Pre-infarction angina is associated with better outcome after myocardial infarction. The aim of this study was to assess whether pre-infarction angina is associated with decreased no-reflow after coronary recanalization. METHODS AND RESULTS:Twenty-three patients underwent intracoronary myocardial contrast echocar...

journal_title：European heart journal

authors： Karila-Cohen D,Czitrom D,Brochet E,Faraggi M,Seknadji P,Himbert D,Juliard JM,Assayag P,Steg PG

更新日期：1999-12-01 00:00:00

abstract：AIMS:To determine very long-term survival and incidence of recurrent interventions following aorto-coronary bypass surgery using venous grafts. METHODS AND RESULTS:A group of 1041 consecutive patients operated upon between 1971 and 1980 were followed for a median of 19 years (range 13-26). Peri-operative mortality was...

journal_title：European heart journal

authors： Veldkamp RF,Valk SD,van Domburg RT,van Herwerden LA,Meeter K

更新日期：2000-05-01 00:00:00

abstract：:Infective endocarditis is associated with significant morbidity and mortality, with valvular destruction and congestive heart failure being more common in patients with echocardiographically discernible vegetations. The transoesophageal approach affords consistently high quality images with excellent structural resolu...

journal_title：European heart journal

authors： Rohmann S,Erbel R,Görge G,Makowski T,Mohr-Kahaly S,Nixdorff U,Drexler M,Meyer J

更新日期：1992-04-01 00:00:00

abstract：AIMS:Intense exercise places disproportionate strain on the right ventricle (RV) which may promote pro-arrhythmic remodelling in some athletes. RV exercise imaging may enable early identification of athletes at risk of arrhythmias. METHODS AND RESULTS:Exercise imaging was performed in 17 athletes with RV ventricular a...

journal_title：European heart journal

authors： La Gerche A,Claessen G,Dymarkowski S,Voigt JU,De Buck F,Vanhees L,Droogne W,Van Cleemput J,Claus P,Heidbuchel H

更新日期：2015-08-07 00:00:00

abstract：AIMS:To quantify the prevalence of coronary artery calcification (CAC) in relation to cardiovascular risk factors in marathon runners, and to study its role for myocardial damage and coronary events. METHODS AND RESULTS:In 108 apparently healthy male marathon runners aged >or=50 years, with >or=5 marathon competitions...

journal_title：European heart journal

authors： Möhlenkamp S,Lehmann N,Breuckmann F,Bröcker-Preuss M,Nassenstein K,Halle M,Budde T,Mann K,Barkhausen J,Heusch G,Jöckel KH,Erbel R,Marathon Study Investigators.,Heinz Nixdorf Recall Study Investigators.

更新日期：2008-08-01 00:00:00

abstract：:Earlier studies have shown that return to work following PTCA is frequent; however PTCA is now performed in patients with more extensive coronary artery disease. The present study was designed to compare the vocational outcome of patients who underwent PTCA in 1980-1982 with that of patients who underwent the procedur...

journal_title：European heart journal

authors： Danchin N,Juilliere Y,Selton-Suty C,Vaillant G,Pernot C,Gilgenkrantz JM,Villemot JP,Mathieu P,Cherrier F

更新日期：1989-12-01 00:00:00

abstract：:The adoption of transradial coronary angiography and coronary intervention is growing because of emerging data on its potential advantages over the femoral approach. As the adoption of radial procedures increases, it is important to understand the remaining challenges of both the technique and its implementation. In t...

journal_title：European heart journal

authors： Rao SV,Bernat I,Bertrand OF

更新日期：2012-10-01 00:00:00

abstract：:Between 1968 and 1984, 78 patients (mean age 43, range 14 to 65 years) underwent combined aortic, mitral and tricuspid surgery (22 triple valve replacements, 56 aortic valve replacements with tricuspid conservative surgery and mitral valve replacement (N = 48), or commissuroplasty (N = 8). Pre-operative consequences o...

journal_title：European heart journal

authors： Michel PL,Houdart E,Ghanem G,Badaoui G,Hage A,Acar J

更新日期：1987-05-01 00:00:00

abstract：AIMS:The objectives of this study were to determine the association of waist circumference (WC) and waist-to-hip ratio (WHR) with the risk of incident cardiovascular disease (CVD) events and to determine whether the strength of association of WC and WHR with CVD risk is different. METHODS AND RESULTS:This meta-regress...

journal_title：European heart journal

authors： de Koning L,Merchant AT,Pogue J,Anand SS

更新日期：2007-04-01 00:00:00

abstract：AIMS:The aim of this study was to evaluate the effect of valve surgery (VS) in infective endocarditis (IE) on 5-year mortality and to evaluate whether conflicting results reported by previous studies could be due to differences in their methodological approaches. METHODS AND RESULTS:Four hundred and forty-nine patient...

journal_title：European heart journal

authors： Bannay A,Hoen B,Duval X,Obadia JF,Selton-Suty C,Le Moing V,Tattevin P,Iung B,Delahaye F,Alla F,AEPEI Study Group.

更新日期：2011-08-01 00:00:00

abstract：AIMS:We explored the association between exposure to environmental tobacco smoke (ETS) and various cardiometabolic biomarkers in 10-year-old children. METHODS AND RESULTS:A population-based cross-sectional study was carried out. Data on ETS exposure and potential confounders were collected by parental questionnaire. A...

journal_title：European heart journal

authors： Nagel G,Arnold FJ,Wilhelm M,Link B,Zoellner I,Koenig W

更新日期：2009-08-01 00:00:00

abstract：AIM:To determine the frequency of pre-existing valvular disease (VD) among patients with acute coronary syndromes (ACS) and to compare the clinical characteristics, clinical course, treatment, and outcomes of ACS patients with and without pre-existing VD. METHODS AND RESULTS:The Euro Heart Survey ACS prospectively enr...

journal_title：European heart journal

authors： Hasdai D,Lev EI,Behar S,Boyko V,Danchin N,Vahanian A,Battler A

更新日期：2003-04-01 00:00:00