Facilitated percutaneous coronary intervention: current concepts, promises, and pitfalls.

Abstract:

:The reperfusion era has dramatically and irrevocably transformed the management of ST-segment elevation myocardial infarction (STEMI). For the patient treated with fibrinolysis as the initial reperfusion strategy, subsequent options which are the subject of some controversy and the focus of this review are (i) facilitated percutaneous coronary intervention (PCI); (ii) pharmacoinvasive approach; (iii) 'Watchful waiting'. We performed a literature search of all available articles on facilitated PCI published in English language on Medline, including randomized controlled trials, meta-analyses, and review articles. This information provided the core for a critical appraisal of the current literature on this controversial topic. On the basis of current available data, facilitated PCI with a thrombolytic agent has no role in everyday clinical practice and facilitated PCI utilizing a glycoprotein IIbIIIa inhibitor agent has no considerable benefit on mortality in STEMI in contemporary practice. The evidence to date suggests that fibrinolytic-facilitated PCI is associated with higher mortality rates and adverse events compared with primary PCI.

journal_name

Eur Heart J

journal_title

European heart journal

authors

Kiernan TJ,Ting HH,Gersh BJ

doi

10.1093/eurheartj/ehm222

subject

Has Abstract

pub_date

2007-07-01 00:00:00

pages

1545-53

issue

13

eissn

0195-668X

issn

1522-9645

pii

ehm222

journal_volume

28

pub_type

杂志文章,评审
  • Natriuretic peptides in cardiovascular diseases: current use and perspectives.

    abstract::The natriuretic peptides (NPs) family, including atrial, B-type, and C-type NPs, is a group of hormones possessing relevant haemodynamic and anti-remodelling actions in the cardiovascular (CV) system. Due to their diuretic, natriuretic, vasorelaxant, anti-proliferative, and anti-hypertrophic effects, they are involved...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/eht466

    authors: Volpe M,Rubattu S,Burnett J Jr

    更新日期:2014-02-01 00:00:00

  • Supplementation with vitamins C and E suppresses leukocyte oxygen free radical production in patients with myocardial infarction.

    abstract::Clinical studies suggest that neutrophil activation during acute myocardial infarction (MI) aggravates tissue injury. Activated neutrophils are an important source of oxygen free radicals (OFR), the injurious effects of which are counteracted by endogenous antioxidants. We have previously shown in healthy subjects tha...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/oxfordjournals.eurheartj.a061045

    authors: Herbaczyńska-Cedro K,K+osiewicz-Wasek B,Cedro K,Wasek W,Panczenko-Kresowska B,Wartanowicz M

    更新日期:1995-08-01 00:00:00

  • Addition of milk prevents vascular protective effects of tea.

    abstract:AIMS:Experimental and clinical studies indicate that tea exerts protection against cardiovascular diseases. However, a question of much debate is whether addition of milk modifies the biological activities of tea. We studied the vascular effects of tea, with or without milk, in humans and elucidated the impact of indiv...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehl442

    authors: Lorenz M,Jochmann N,von Krosigk A,Martus P,Baumann G,Stangl K,Stangl V

    更新日期:2007-01-01 00:00:00

  • Failure of provision of antibiotic prophylaxis for 'at risk' cardiac patients: impetus for improvement required from cardiologists.

    abstract::We conducted a survey by questionnaire to assess whether patients 'at risk' from infective endocarditis are aware of the need for good dental hygiene and antibiotic prophylaxis, and receive appropriate advice or treatment. Of 189 patients surveyed, half had told a dentist about their heart, 8% were aware of a dental p...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/14.6.812

    authors: Forbat LN,Skehan JD

    更新日期:1993-06-01 00:00:00

  • The European Study of Epidemiology and Treatment of Cardiac Inflammatory Disease (ESETCID).

    abstract::Diagnosis of myocarditis has improved with the application of new techniques such as immunohistochemistry, polymerase chain reaction, in situ hybridization and Southern blot in endomyocardial biopsies. Treatment of inflammatory heart disease is still difficult and not yet validated by a study with patient numbers suff...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/16.suppl_o.173

    authors: Maisch B,Hufnagel G,Schönian U,Hengstenberg C

    更新日期:1995-12-01 00:00:00

  • Relationship between admission serum sodium concentration and clinical outcomes in patients hospitalized for heart failure: an analysis from the OPTIMIZE-HF registry.

    abstract:AIMS:Hyponatraemia has been shown to be an independent predictor of mortality in selected patients with heart failure enrolled in clinical trials. The predictive value of hyponatraemia has not been evaluated in unselected patients hospitalized with heart failure. METHODS AND RESULTS:OPTIMIZE-HF is a registry and perfo...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehl542

    authors: Gheorghiade M,Abraham WT,Albert NM,Gattis Stough W,Greenberg BH,O'Connor CM,She L,Yancy CW,Young J,Fonarow GC,OPTIMIZE-HF Investigators and Coordinators.

    更新日期:2007-04-01 00:00:00

  • Current therapy and outcome of Eisenmenger syndrome: data of the German National Register for congenital heart defects.

    abstract:AIMS:We aimed to assess the contemporary outcome of Eisenmenger syndrome (ES), delineate the use of disease targeting therapies (DTT) in these patients and to investigate the effect of treatment on outcome in the community. METHODS AND RESULTS:Patients with ES were systematically identified from the German National Re...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehv743

    authors: Diller GP,Körten MA,Bauer UM,Miera O,Tutarel O,Kaemmerer H,Berger F,Baumgartner H,German Competence Network for Congenital Heart Defects Investigators.

    更新日期:2016-05-07 00:00:00

  • Silent healing of spontaneous plaque disruption demonstrated by intracoronary ultrasound.

    abstract::Intracoronary ultrasound was performed at diagnostic coronary angiography and 10 days later in a 45-year-old patient with a 3-day history of acute inferior myocardial infarction. Coronary angiography showed considerable stenosis (80%) in the distal right coronary artery (RCA) (pre the crux) and what appeared to be a d...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a061061

    authors: Ge J,Haude M,Görge G,Liu F,Erbel R

    更新日期:1995-08-01 00:00:00

  • Diastolic heart failure.

    abstract::Diastolic heart disease is common and appears to be the primary abnormality in a substantial proportion of all patients with CHF. The epidemiology and natural history of the condition appears different to that of systolic heart failure, resulting in significant morbidity although contributing little to overall mortali...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/oxfordjournals.eurheartj.a060453

    authors: Wheeldon NM,Clarkson P,MacDonald TM

    更新日期:1994-12-01 00:00:00

  • Molecular imaging-guided repair after acute myocardial infarction by targeting the chemokine receptor CXCR4.

    abstract:AIMS :Balance between inflammatory and reparative leucocytes allows optimal healing after myocardial infarction (MI). Interindividual heterogeneity evokes variable functional outcome complicating targeted therapy. We aimed to characterize infarct chemokine CXC-motif receptor 4 (CXCR4) expression using positron emission...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehaa598

    authors: Hess A,Derlin T,Koenig T,Diekmann J,Wittneben A,Wang Y,Wester HJ,Ross TL,Wollert KC,Bauersachs J,Bengel FM,Thackeray JT

    更新日期:2020-10-01 00:00:00

  • AntagomiR directed against miR-20a restores functional BMPR2 signalling and prevents vascular remodelling in hypoxia-induced pulmonary hypertension.

    abstract:AIMS:Dysregulation of the bone morphogenetic protein receptor type 2 (BMPR2) is a hallmark feature that has been described in several forms of pulmonary hypertension. We recently identified the microRNA miR-20a within a highly conserved pathway as a regulator of the expression of BMPR2. To address the pathophysiologica...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehs060

    authors: Brock M,Samillan VJ,Trenkmann M,Schwarzwald C,Ulrich S,Gay RE,Gassmann M,Ostergaard L,Gay S,Speich R,Huber LC

    更新日期:2014-12-01 00:00:00

  • Risk of hospitalization for heart failure in patients with type 2 diabetes newly treated with DPP-4 inhibitors or other oral glucose-lowering medications: a retrospective registry study on 127,555 patients from the Nationwide OsMed Health-DB Database.

    abstract:AIMS:Oral glucose-lowering medications are associated with excess risk of heart failure (HF). Given the absence of comparative data among drug classes, we performed a retrospective study in 32 Health Services of 16 Italian regions accounting for a population of 18 million individuals, to assess the association between ...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehv301

    authors: Fadini GP,Avogaro A,Degli Esposti L,Russo P,Saragoni S,Buda S,Rosano G,Pecorelli S,Pani L,OsMed Health-DB Network.

    更新日期:2015-09-21 00:00:00

  • Endocarditis on a left atrial myxoma.

    abstract::A 55-year-old woman presented with fever and malaise. Three blood cultures were positive for Streptococcus sanguis. A diagnosis of endocarditis was made and the patient was treated with intravenous penicillin and gentamicin. Endocardiography revealed a large left atrial tumour. At operation a myxoma covered by deposit...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a060109

    authors: ten Berg JM,Elbers HR,Defauw JJ,Plokker HW

    更新日期:1992-11-01 00:00:00

  • Prognostic value of left ventricular volume response during dobutamine stress echocardiography.

    abstract:AIMS:An abnormal left ventricular volume response during dobutamine echocardiography identified patients with severe coronary artery disease. The aim of the study was to assess the prognostic value of left ventricular volume changes during dobutamine stress echocardiography in 136 patients. METHODS AND RESULTS:Endpoin...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a015139

    authors: Coletta C,Galati A,Ricci R,Sestili A,Guagnozzi G,Re F,Ceci V

    更新日期:1997-10-01 00:00:00

  • Coronary artery spasm in a transplant patient.

    abstract::The mechanism of coronary spasm is poorly understood. We report a case of coronary artery spasm in a cardiac transplant patient. Pharmacologic testing indicated denervation of the patient's heart. Therefore coronary artery spasm may occur despite cardiac denervation. This case demonstrates that intact autonomic nervou...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a062543

    authors: Cattan S,Drobinski G,Artigou JY,Grogogeat Y,Cabrol C

    更新日期:1988-05-01 00:00:00

  • Infection and inflammation as risk factors for myocardial infarction.

    abstract::Recent studies have illustrated that in addition to the well known risk factors, such as lipoproteins, smoking, hypertension, there are others that cause atherosclerosis and myocardial infarction. Our knowledge of atherosclerotic lesions has increased. We now know that atherosclerotic changes are due to inflammatory c...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:

    authors: Nieminen MS,Mattila K,Valtonen V

    更新日期:1993-12-01 00:00:00

  • Stent thrombosis following bare-metal stent implantation: success of emergency percutaneous coronary intervention and predictors of adverse outcome.

    abstract:AIMS:To investigate the efficacy and outcome of emergency percutaneous coronary interventions (PCI) in patients with stent thrombosis. METHODS AND RESULTS:Between 1995 and 2003, 6058 patients underwent bare-metal stent implantation, of which 95 (1.6%) patients suffered from stent thrombosis. The timing of stent thromb...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehi135

    authors: Wenaweser P,Rey C,Eberli FR,Togni M,Tüller D,Locher S,Remondino A,Seiler C,Hess OM,Meier B,Windecker S

    更新日期:2005-06-01 00:00:00

  • Exercise unmasks distinct pathophysiologic features in heart failure with preserved ejection fraction and pulmonary vascular disease.

    abstract:Aims:Pulmonary hypertension (PH) and pulmonary vascular disease (PVD) are common and associated with adverse outcomes in heart failure with preserved ejection fraction (HFpEF). Little is known about the impact of PVD on the pathophysiology of exercise intolerance. Methods and results:Heart failure with preserved eject...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehy331

    authors: Gorter TM,Obokata M,Reddy YNV,Melenovsky V,Borlaug BA

    更新日期:2018-08-07 00:00:00

  • Enhanced functional response of CD133+ circulating progenitor cells in patients early after acute myocardial infarction.

    abstract:AIMS:Circulating progenitor cells (PC) may contribute to myocardial recovery following infarction. Growth factors including VEGF are produced during ischaemia and stimulate PC release and activation. In this study, we focused on the functional chemotactic response of PC to VEGF in subjects early after myocardial ischae...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehm542

    authors: Vöö S,Eggermann J,Dunaeva M,Ramakers-van Oosterhoud C,Waltenberger J

    更新日期:2008-01-01 00:00:00

  • Genes for blood pressure: an opportunity to understand hypertension.

    abstract::Hypertension (HTN) is quantitatively the major cardiovascular risk factor and responsible for ∼50% of cardiovascular morbidity and mortality. Blood pressure (BP) is also a classical complex genetic trait with heritability estimates of 30-50%. Although much is known about BP regulation, the intrinsic origin of essentia...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/ehs455

    authors: Ehret GB,Caulfield MJ

    更新日期:2013-04-01 00:00:00

  • Mechanisms of angina pectoris in syndrome X assessed by myocardial perfusion dynamics and heart rate variability.

    abstract::The fundamental abnormality in syndrome X (angina pectoris, ischaemia-like stress ECG despite angiographically normal coronary arteries) might be patchily distributed increased tone in pre-arteriolar coronary vessels with compensatory release of adenosine. The aim of this study was to confirm this hypothesis and to ex...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a060780

    authors: Meeder JG,Blanksma PK,Crijns HJ,Anthonio RL,Pruim J,Brouwer J,de Jong RM,van der Wall EE,Vaalburg W,Lie KI

    更新日期:1995-11-01 00:00:00

  • International Expert Consensus Document on Takotsubo Syndrome (Part II): Diagnostic Workup, Outcome, and Management.

    abstract::The clinical expert consensus statement on takotsubo syndrome (TTS) part II focuses on the diagnostic workup, outcome, and management. The recommendations are based on interpretation of the limited clinical trial data currently available and experience of international TTS experts. It summarizes the diagnostic approac...

    journal_title:European heart journal

    pub_type: 共识发展会议,杂志文章

    doi:10.1093/eurheartj/ehy077

    authors: Ghadri JR,Wittstein IS,Prasad A,Sharkey S,Dote K,Akashi YJ,Cammann VL,Crea F,Galiuto L,Desmet W,Yoshida T,Manfredini R,Eitel I,Kosuge M,Nef HM,Deshmukh A,Lerman A,Bossone E,Citro R,Ueyama T,Corrado D,Kurisu S,

    更新日期:2018-06-07 00:00:00

  • Effects of rosuvastatin on atrial fibrillation occurrence: ancillary results of the GISSI-HF trial.

    abstract:AIMS:This ancillary analysis of the GISSI-HF database aims at assessing the effect of rosuvastatin on the occurrence of atrial fibrillation (AF) in patients with chronic heart failure (HF) who were not in AF at study entry. METHODS AND RESULTS:GISSI-HF was a double-blind, placebo-controlled trial testing n-3 PUFA and ...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/ehp357

    authors: Maggioni AP,Fabbri G,Lucci D,Marchioli R,Franzosi MG,Latini R,Nicolosi GL,Porcu M,Cosmi F,Stefanelli S,Tognoni G,Tavazzi L,GISSI-HF Investigators.

    更新日期:2009-10-01 00:00:00

  • Quantifying the heart failure epidemic: prevalence, incidence rate, lifetime risk and prognosis of heart failure The Rotterdam Study.

    abstract:AIMS:To determine the prevalence, incidence rate, lifetime risk and prognosis of heart failure. METHODS AND RESULTS:The Rotterdam Study is a prospective population-based cohort study in 7983 participants aged > or =55. Heart failure was defined according to criteria of the European Society of Cardiology. Prevalence wa...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ehj.2004.06.038

    authors: Bleumink GS,Knetsch AM,Sturkenboom MC,Straus SM,Hofman A,Deckers JW,Witteman JC,Stricker BH

    更新日期:2004-09-01 00:00:00

  • ACE inhibitors and their influence on inflammation, bronchial reactivity and cough.

    abstract::Orally active angiotensin converting enzyme (ACE) inhibitors have been successfully used in the treatment of congestive heart failure and hypertension. However, adverse skin reactions, such as angioneurotic oedema have been reported following such medication. Furthermore, these drugs have been associated with a persis...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/eurheartj/15.suppl_c.52

    authors: Andersson RG,Persson K

    更新日期:1994-08-01 00:00:00

  • Nitric oxide inhalation for myocardial infarction patients.

    abstract::Nitric oxide inhalation in myocardial infarction patients sends mixed messages, but may offer some benefit. ...

    journal_title:European heart journal

    pub_type: 新闻

    doi:

    authors: Tofield A

    更新日期:2015-05-14 00:00:00

  • Risk factors for cardiovascular disease in patients with periodontitis.

    abstract:AIMS:This study compared plasma levels of established risk markers for atherosclerosis and indices of inflammation in 50 patients with severe periodontitis to those in 46 healthy cases. METHODS AND RESULTS:Full blood counts were performed and levels of high density lipoproteins (HDL), total cholesterol, haptoglobin, e...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ehj.2003.09.016

    authors: Buhlin K,Gustafsson A,Pockley AG,Frostegård J,Klinge B

    更新日期:2003-12-01 00:00:00

  • Prospective cohort study of C-reactive protein as a predictor of clinical events in adults with congenital heart disease: results of the Boston adult congenital heart disease biobank.

    abstract:Aims:Despite the well-defined association of high-sensitivity hsCRP with cardiovascular outcomes in apparently healthy adults and those with acquired heart disease, the relevance of this inflammatory marker in adults with congenital heart disease (ACHD) remains unclear. We aimed to examine the clinical correlates and p...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehy362

    authors: Opotowsky AR,Valente AM,Alshawabkeh L,Cheng S,Bradley A,Rimm EB,Landzberg MJ

    更新日期:2018-09-07 00:00:00

  • Clinical course and prognosis of patients with typical and atypical hypertrophic obstructive and with hypertrophic non-obstructive cardiomyopathy.

    abstract::In a total of 339 patients with hypertrophic cardiomyopathies (typical HOCM, n = 224; atypical HOCM, n = 30; HNCM, n = 80) the clinical course, the Sokolow-Lyon index in the ECG and the prognosis as demonstrated by cumulative survival rates were analysed to get more differentiated information for the characterization ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/4.suppl_f.145

    authors: Loogen F,Kuhn H,Gietzen F,Lösse B,Schulte HD,Bircks W

    更新日期:1983-11-01 00:00:00

  • Identification of pacemaker dependent patients by serial decremental rate inhibition.

    abstract::In a study of the concept of pacemaker dependence, 86 patients who had permanent ventricular demand (VVI) pacemakers implanted for more than six months and were in predominantly paced rhythm underwent repeated interruption of pacing both abruptly and after gradual reduction of paced rate. Non-invasive pace slowing was...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a061777

    authors: Crick JC,Rokas S,Sowton E

    更新日期:1985-10-01 00:00:00