Biological signals of cardiac hypertrophy.

abstract：:The pharmacokinetics of glyceryl trinitrate are still not completely understood. The substance disappears rapidly from plasma largely by extrahepatic mechanisms. It is converted in glyceryl dinitrates and glyceryl mononitrates. After transdermal application of a controlled delivery system, plasma concentrations of gly...

journal_title：European heart journal

authors： Bogaert MG

更新日期：1988-01-01 00:00:00

abstract：Aims:Despite the well-defined association of high-sensitivity hsCRP with cardiovascular outcomes in apparently healthy adults and those with acquired heart disease, the relevance of this inflammatory marker in adults with congenital heart disease (ACHD) remains unclear. We aimed to examine the clinical correlates and p...

journal_title：European heart journal

authors： Opotowsky AR,Valente AM,Alshawabkeh L,Cheng S,Bradley A,Rimm EB,Landzberg MJ

更新日期：2018-09-07 00:00:00

abstract：AIMS:To investigate personality traits and sympatho-vagal modulation of heart rate variability (HRV) during acute myocardial infarction (AMI), assessing their relationships and their long-term prognostic value. METHODS AND RESULTS:Psychological traits and 24 h HRV were prospectively investigated in 246 patients at dis...

journal_title：European heart journal

authors： Carpeggiani C,Emdin M,Bonaguidi F,Landi P,Michelassi C,Trivella MG,Macerata A,L'Abbate A

更新日期：2005-08-01 00:00:00

abstract：AIMS:We estimated the association between outdoor light at night at the residence and risk of coronary heart disease (CHD) within a prospective cohort of older adults in Hong Kong. METHODS AND RESULTS:Over a median of 11 years of follow-up, we identified 3772 incident CHD hospitalizations and 1695 CHD deaths. Annual l...

journal_title：European heart journal

authors： Sun S,Cao W,Ge Y,Ran J,Sun F,Zeng Q,Guo M,Huang J,Lee RS,Tian L,Wellenius GA

更新日期：2020-11-17 00:00:00

abstract：:Twelve patients with the long QT syndrome were studied to determine the usefulness of 123I-metaiodobenzylguanidine (MIBG) single-photon emission tomography (SPECT) at 2 h and 6 h after injection; the results were compared to 10 healthy volunteers (controls). Uptake of MIBG in the left ventricle at 2 h after injection ...

journal_title：European heart journal

authors： Müller KD,Jakob H,Neuzner J,Grebe SF,Schlepper M,Pitschner HF

更新日期：1993-03-01 00:00:00

abstract：AIMS:No-reflow after a primary percutaneous coronary intervention (PCI) is associated with a high incidence of left ventricular (LV) failure and a poor prognosis. Endothelin-1 (ET-1) is a potent endothelium-derived vasoconstrictor peptide and an important modulator of neutrophil function. Elevated systemic ET-1 levels ...

journal_title：European heart journal

authors： Niccoli G,Lanza GA,Shaw S,Romagnoli E,Gioia D,Burzotta F,Trani C,Mazzari MA,Mongiardo R,De Vita M,Rebuzzi AG,Lüscher TF,Crea F

更新日期：2006-08-01 00:00:00

abstract：AIMS:To assess EuroSCORE performance in predicting in-hospital mortality in on-pump coronary artery bypass grafting (CABG) and off-pump coronary artery bypass grafting (OPCAB). METHODS AND RESULTS:Additive and logistic EuroSCORE were computed for consecutive patients undergoing CABG (n = 3440, 75%) or OPCAB (n = 1140,...

journal_title：European heart journal

authors： Parolari A,Pesce LL,Trezzi M,Loardi C,Kassem S,Brambillasca C,Miguel B,Tremoli E,Biglioli P,Alamanni F

更新日期：2009-02-01 00:00:00

abstract：Aims:Optimal blood pressure for prevention of cardiovascular (CV) events in patients with Type 2 diabetes mellitus (T2DM) remains uncertain and there is concern for increased risk with low diastolic blood pressure (DBP). This study analysed the association between blood pressure and CV outcomes in high-risk patients wi...

journal_title：European heart journal

authors： Bergmark BA,Scirica BM,Steg PG,Fanola CL,Gurmu Y,Mosenzon O,Cahn A,Raz I,Bhatt DL,SAVOR-TIMI 53 Investigators.

更新日期：2018-06-21 00:00:00

abstract：:The clinical expert consensus statement on takotsubo syndrome (TTS) part II focuses on the diagnostic workup, outcome, and management. The recommendations are based on interpretation of the limited clinical trial data currently available and experience of international TTS experts. It summarizes the diagnostic approac...

journal_title：European heart journal

authors： Ghadri JR,Wittstein IS,Prasad A,Sharkey S,Dote K,Akashi YJ,Cammann VL,Crea F,Galiuto L,Desmet W,Yoshida T,Manfredini R,Eitel I,Kosuge M,Nef HM,Deshmukh A,Lerman A,Bossone E,Citro R,Ueyama T,Corrado D,Kurisu S,

更新日期：2018-06-07 00:00:00

abstract：BACKGROUND:Polymorphisms within renin angiotensin system genes have been investigated as risk factors for coronary artery disease in different populations with contradicting results. The aim of this study was to investigate the genotype distribution and the allele frequencies of ACE, AT1R and AGT gene polymorphisms as ...

journal_title：European heart journal

authors： Fatini C,Abbate R,Pepe G,Battaglini B,Gensini F,Ruggiano G,Gensini GF,Guazzelli R

更新日期：2000-04-01 00:00:00

abstract：AIMS:The aim of this study was to assess whether perioperative N-acetylcysteine (NAC), an antioxidant, prevents acute renal injury (ARI) after cardiac surgery. METHODS AND RESULTS:We performed a systematic review of randomized controlled trials (RCTs) of NAC in adult cardiac surgery patients. The RCTs were identified ...

journal_title：European heart journal

authors： Adabag AS,Ishani A,Bloomfield HE,Ngo AK,Wilt TJ

更新日期：2009-08-01 00:00:00

abstract：:Intravenous adenosine proved effective in eight out of ten episodes of acute spontaneous supraventricular tachycardia. AV node blockade induced by adenosine occurred 20 s after injection, and disappeared very quickly. Side-effects were transient and never serious. Therefore, it is thought that adenosine can be propose...

journal_title：European heart journal

authors： Munoz A,Leenhardt A,Sassine A,Galley P,Puech P

更新日期：1984-09-01 00:00:00

abstract：AIMS:Atrial fibrillation (AF) is associated with abnormal sarcoplasmic reticulum (SR) calcium release, which is promoted by adenosine A(2A) receptor (A(2A)R) activation. Here, we tested the hypothesis that abnormal calcium release in AF is linked to A(2A)R remodelling. METHODS AND RESULTS:Western blotting and quantita...

journal_title：European heart journal

authors： Llach A,Molina CE,Prat-Vidal C,Fernandes J,Casadó V,Ciruela F,Lluís C,Franco R,Cinca J,Hove-Madsen L

更新日期：2011-03-01 00:00:00

abstract：:We performed echocardiographic evaluation of 20 male veteran endurance runners (mean age 56 +/- 7 years) and compared them with a group of age-matched controls. All the runners had run at least 25 miles per week for more than 25 years. Although only four athletes showed voltage ECG evidence of left ventricular hypertr...

journal_title：European heart journal

authors： Northcote RJ,McKillop G,Todd IC,Canning GP

更新日期：1990-01-01 00:00:00

abstract：AIMS:In the dual antiplatelet therapy (DAPT) study, continued thienopyridine beyond 12 months after drug-eluting stent placement was associated with increased mortality compared with placebo. We sought to evaluate factors related to mortality in randomized patients receiving either drug-eluting or bare metal stents in ...

journal_title：European heart journal

authors： Mauri L,Elmariah S,Yeh RW,Cutlip DE,Steg PG,Windecker S,Wiviott SD,Cohen DJ,Massaro JM,D'Agostino RB Sr,Braunwald E,Kereiakes DJ,DAPT Study Investigators.

更新日期：2016-01-21 00:00:00

abstract：AIMS:Exposure of tissue factor (TF) is a critical proximal step in the pathogenesis of acute coronary syndromes. Sunol-cH36, a chimaeric monoclonal antibody to TF, blocks binding of factor X to the TF:VIIa complex. This report describes the first completed trial of Sunol-cH36 in humans. METHODS AND RESULTS:We assessed...

journal_title：European heart journal

authors： Morrow DA,Murphy SA,McCabe CH,Mackman N,Wong HC,Antman EM

更新日期：2005-04-01 00:00:00

abstract：AIMS:Reperfusion injury following acute myocardial infarction impacts not only on the myocardium but also on the coronary microcirculation, and microembolization from the culprit lesion contributes to microvascular obstruction. Prior experimental studies have not accounted for microembolization in ischaemia/reperfusion...

journal_title：European heart journal

authors： Skyschally A,Walter B,Heusch G

更新日期：2013-11-01 00:00:00

abstract：AIMS:In patients with sick sinus syndrome, bradycardia can be treated with a single-lead pacemaker or a dual-chamber pacemaker. Previous trials have revealed that pacing modes preserving atrio-ventricular synchrony are superior to single-lead ventricular pacing, but it remains unclear if there is any difference between...

journal_title：European heart journal

authors： Nielsen JC,Thomsen PE,Højberg S,Møller M,Vesterlund T,Dalsgaard D,Mortensen LS,Nielsen T,Asklund M,Friis EV,Christensen PD,Simonsen EH,Eriksen UH,Jensen GV,Svendsen JH,Toff WD,Healey JS,Andersen HR,DANPACE Investigato

更新日期：2011-03-01 00:00:00

abstract：:The structural properties of cardiac isomyosins from several species were compared using native gel electrophoresis, analysis of proteolytic digests, analysis of monoclonal antibody reactivity to specific proteolytic fragments on electroblots and S1 nuclease mapping with cDNA probes. The structure of specific regions ...

journal_title：European heart journal

authors： Clark WA,Everett AW,Chizzonite RA,Eisenberg BR,Zak R

更新日期：1984-12-01 00:00:00

abstract：AIMS:The transversal distribution of coronary atherosclerotic plaques (AP) (myocardial vs pericardial) affects vessel remodelling. The aim of this study was to define the impact of transversal lesion distribution on vessel remodelling in proximal and distal coronary segments using a 3D intravascular ultrasound (IVUS) r...

journal_title：European heart journal

authors： Prati F,Arbustini E,Labellarte A,Sommariva L,Pawlowski T,Manzoli A,Pagano A,Motolese M,Boccanelli A

更新日期：2003-02-01 00:00:00

abstract：:Contradictory two-dimensional echocardiographic findings have been reported in relation to the role of prolapse of the mitral valve and lack of systolic leaflet coaptation in mitral regurgitation secondary to coronary heart disease. A prospective study of 22 patients with chronic coronary heart disease and mitral regu...

journal_title：European heart journal

authors： Ballester M,Tasca R,Marin L,Rees S,Rickards A,McDonald L

更新日期：1983-08-01 00:00:00

abstract：AIMS:in hypertrophic cardiomyopathy (HCM), the following five risk factors have a major role in the primary prevention of sudden death (SD): family history of SD (FHSD), syncope, massive wall thickness (MWTh) >30 mm, non-sustained ventricular tachycardia (nsVT) in Holter monitoring of electrocardiography, and abnormal ...

journal_title：European heart journal

authors： Dimitrow PP,Chojnowska L,Rudzinski T,Piotrowski W,Ziólkowska L,Wojtarowicz A,Wycisk A,Dabrowska-Kugacka A,Nowalany-Kozielska E,Sobkowicz B,Wróbel W,Aleszewicz-Baranowska J,Rynkiewicz A,Loboz-Grudzien K,Marchel M,Wysokinski

更新日期：2010-12-01 00:00:00

abstract：:The safety of calcium antagonists has recently become a controversial issue among cardiologists. Thus, the role of calcium antagonists in the treatment of myocardial infarction and in secondary cardiovascular prevention is under review. As a consequence, the concept that the words 'calcium antagonists' comprise variou...

journal_title：European heart journal

authors： Ferrari R

更新日期：1997-01-01 00:00:00

abstract：AIMS:The 2019 report from the European Society of Cardiology (ESC) Atlas provides a contemporary analysis of cardiovascular disease (CVD) statistics across 56 member countries, with particular emphasis on international inequalities in disease burden and healthcare delivery together with estimates of progress towards me...

journal_title：European heart journal

authors： Timmis A,Townsend N,Gale CP,Torbica A,Lettino M,Petersen SE,Mossialos EA,Maggioni AP,Kazakiewicz D,May HT,De Smedt D,Flather M,Zuhlke L,Beltrame JF,Huculeci R,Tavazzi L,Hindricks G,Bax J,Casadei B,Achenbach S,Wrig

更新日期：2020-01-01 00:00:00

abstract：AIMS:To evaluate the association between occupational and leisure-time physical activity (PA), ownership of goods promoting sedentary behaviour, and the risk of myocardial infarction (MI) in different socio-economic populations of the world. Studies in developed countries have found low PA as a risk factor for cardiova...

journal_title：European heart journal

authors： Held C,Iqbal R,Lear SA,Rosengren A,Islam S,Mathew J,Yusuf S

更新日期：2012-02-01 00:00:00

abstract：:This state-of-the-art review aims to provide an up-to-date look at breakthrough omic technologies that are helping to unravel heart failure (HF) disease mechanisms and heterogeneity. Genomics, transcriptomics, proteomics, and metabolomics in HF are reviewed in depth. In addition, there is a thorough, expert discussion...

journal_title：European heart journal

authors： Bayes-Genis A,Liu PP,Lanfear DE,de Boer RA,González A,Thum T,Emdin M,Januzzi JL

更新日期：2020-09-21 00:00:00

abstract：:The effect of diuretic dose on the haemodynamic response to captopril was assessed in nine patients with chronic cardiac failure. Each patient was given an intravenous dose of captopril while maintained on (a) a low dose diuretic regime, and (b) a high dose diuretic regime. Activity of the renin angiotensin aldosteron...

journal_title：European heart journal

authors： Flapan AD,Davies E,Williams BC,Shaw TR,Edwards CR

更新日期：1992-07-01 00:00:00

abstract：:We found that the incidence and distribution of conduction system disease simultaneously affecting several levels of the system had been incompletely described. We therefore analysed all patients in whom conduction disease had been diagnosed and a complete electrophysiological study of the conduction system had been m...

journal_title：European heart journal

authors： Rasmussen K,Myhre ES,Gunnes P,Wang H

更新日期：1983-02-01 00:00:00

abstract：AIMS:The long QT syndrome is mainly defined by QT interval prolongation (QTc > 0.44s). However, data obtained in genotyped patients showed that resting QTc measurement alone may be inaccurate for ascertaining the phenotype. The aim of this study was to evaluate the diagnostic performance of QT interval rate-dependence ...

journal_title：European heart journal

authors： Neyroud N,Maison-Blanche P,Denjoy I,Chevret S,Donger C,Dausse E,Fayn J,Badilini F,Menhabi N,Schwartz K,Guicheney P,Coumel P

更新日期：1998-01-01 00:00:00

abstract：AIMS:Patients with atrial fibrillation (AF) present with symptoms of myocardial ischaemia despite exclusion of coronary artery disease. A small vessel disease has been suggested. We quantified myocardial perfusion, perfusion reserve, and coronary vascular resistance (CVR) in AF patients using positron emission tomograp...

journal_title：European heart journal

authors： Range FT,Schäfers M,Acil T,Schäfers KP,Kies P,Paul M,Hermann S,Brisse B,Breithardt G,Schober O,Wichter T

更新日期：2007-09-01 00:00:00