The effect of habitual sustained endurance exercise on cardiac structure and function.

Abstract:

:We performed echocardiographic evaluation of 20 male veteran endurance runners (mean age 56 +/- 7 years) and compared them with a group of age-matched controls. All the runners had run at least 25 miles per week for more than 25 years. Although only four athletes showed voltage ECG evidence of left ventricular hypertrophy, using echocardiography, 10 athletes had evidence of left ventricular hypertrophy. Thus electrocardiography is insufficiently sensitive to detect LVH in this group (10%). Left ventricular posterior wall thickness and left ventricular mass were significantly greater in the athletes, the difference becoming more marked when LV mass was corrected for body surface area and, consequently, the wall thickness: cavity diameter ratio was increased (P less than 0.04). There was no difference between the two groups in left ventricular performance and no correlation between left ventricular mass and running ability. Thus, veteran runners develop structural cardiac changes similar to younger power-trained athletes and do not show characteristics normally expected of 'volume overload' which is thought to occur in running.

journal_name

Eur Heart J

journal_title

European heart journal

authors

Northcote RJ,McKillop G,Todd IC,Canning GP

doi

10.1093/oxfordjournals.eurheartj.a059585

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

17-22

issue

1

eissn

0195-668X

issn

1522-9645

journal_volume

11

pub_type

杂志文章
  • Reactive thrombocytosis and stroke following cardiopulmonary bypass surgery: case report on three patients.

    abstract::Reactive thrombocytosis following cardiopulmonary bypass surgery is generally considered to be a benign condition which is transient and does not require specific therapy. We describe three patients who developed stroke in association with reactive thrombocytosis in the late recovery period following cardiopulmonary b...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a060642

    authors: Crowley JJ,Hannigan M,Daly K

    更新日期:1994-08-01 00:00:00

  • Improvement in risk stratification with the combination of the tumour marker antigen carbohydrate 125 and brain natriuretic peptide in patients with acute heart failure.

    abstract:AIM:Elevated brain natriuretic peptide (BNP) and tumour marker antigen carbohydrate 125 (CA125) levels have shown to be associated with higher risk for adverse outcomes in patients with acute heart failure (AHF). Nevertheless, no attempt has been made to explore the utility of combining these two biomarkers. We sought ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehq142

    authors: Núñez J,Sanchis J,Bodí V,Fonarow GC,Núñez E,Bertomeu-González V,Miñana G,Consuegra L,Bosch MJ,Carratalá A,Chorro FJ,Llàcer A

    更新日期:2010-07-01 00:00:00

  • Failure of provision of antibiotic prophylaxis for 'at risk' cardiac patients: impetus for improvement required from cardiologists.

    abstract::We conducted a survey by questionnaire to assess whether patients 'at risk' from infective endocarditis are aware of the need for good dental hygiene and antibiotic prophylaxis, and receive appropriate advice or treatment. Of 189 patients surveyed, half had told a dentist about their heart, 8% were aware of a dental p...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/14.6.812

    authors: Forbat LN,Skehan JD

    更新日期:1993-06-01 00:00:00

  • Incidence and prognostic significance of sustained ventricular tachycardias in heart failure patients implanted with biventricular pacemakers without a back-up defibrillator: results from the prospective, multicentre, Mona Lisa cohort study.

    abstract:AIMS:The aim of this study was to investigate the 12-month incidence, predictive factors, and prognosis of sustained ventricular tachycardia (VT) in chronic heart failure patients implanted with biventricular pacemakers without a back-up defibrillator (CRT-P), assessed by continuous intracardiac ventricular electrogram...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehp071

    authors: Boveda S,Marijon E,Jacob S,Defaye P,Winter JB,Bulava A,Gras D,Albenque JP,Combes N,Pavin D,Delarche N,Teubl A,Lambiez M,Chevalier P,Mona Lisa Study Group.

    更新日期:2009-05-01 00:00:00

  • Long-term clinical outcome and performance of transcatheter aortic valve replacement with a self-expandable bioprosthesis.

    abstract:AIMS :In the last decade, transcatheter aortic valve (TAV) replacement determined a paradigm shift in the treatment of patients with severe symptomatic aortic stenosis. Data on long-term TAV performance are still limited. We sought to evaluate the clinical and haemodynamic outcomes of the CoreValve self-expandable valv...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehz925

    authors: Testa L,Latib A,Brambilla N,De Marco F,Fiorina C,Adamo M,Giannini C,Angelillis M,Barbanti M,Sgroi C,Poli A,Ferrara E,Bruschi G,Russo CF,Matteo M,De Felice F,Musto C,Curello S,Colombo A,Tamburino C,Petronio AS,Be

    更新日期:2020-05-21 00:00:00

  • Atrial electrical and structural abnormalities in an ovine model of chronic blood pressure elevation after prenatal corticosteroid exposure: implications for development of atrial fibrillation.

    abstract:AIMS:Elevated blood pressure (EBP) is the most prevalent and potentially modifiable risk factor for AF, yet little is known of its atrial effects. We aimed to characterize the atrial electrical and structural changes in a chronic ovine model of EBP after prenatal corticosteroid exposure. METHODS AND RESULTS:Twelve she...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehl360

    authors: Kistler PM,Sanders P,Dodic M,Spence SJ,Samuel CS,Zhao C,Charles JA,Edwards GA,Kalman JM

    更新日期:2006-12-01 00:00:00

  • Genetic defects in a His-Purkinje system transcription factor, IRX3, cause lethal cardiac arrhythmias.

    abstract:AIM:Ventricular fibrillation (VF), the main cause of sudden cardiac death (SCD), occurs most frequently in the acute phase of myocardial infarction: a certain fraction of VF, however, develops in an apparently healthy heart, referred as idiopathic VF. The contribution of perturbation in the fast conduction system in th...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehv449

    authors: Koizumi A,Sasano T,Kimura W,Miyamoto Y,Aiba T,Ishikawa T,Nogami A,Fukamizu S,Sakurada H,Takahashi Y,Nakamura H,Ishikura T,Koseki H,Arimura T,Kimura A,Hirao K,Isobe M,Shimizu W,Miura N,Furukawa T

    更新日期:2016-05-07 00:00:00

  • Sinus of Valsalva aneurysm obstructing coronary arterial flow: case report and collective review of the literature.

    abstract::One case of unruptured sinus of Valsalva aneurysm causing left coronary artery compression and lethal myocardial infarction in a 39-year old woman is described. In reviewing the literature, 15 previously published cases of sinus of Valsalva aneurysms disturbing coronary flow were found. It is concluded that the mechan...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a061811

    authors: Brandt J,Jögi P,Lührs C

    更新日期:1985-12-01 00:00:00

  • Excimer laser coronary angioplasty: experience with a prototype multifibre catheter in patients with stable angina pectoris.

    abstract::Percutaneous excimer laser coronary angioplasty (ELCA) was performed in a first group of 20 patients with stable angina pectoris caused by significant coronary stenosis, and long-term follow-up was evaluated. Prototype 4 to 5.5 French multifibre catheters with 18-20 quartz fibres of 100 microns diameter, concentricall...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a060172

    authors: Kochs M,Haerer W,Eggeling T,Hoeher M,Schmidt A,Hombach V

    更新日期:1992-03-01 00:00:00

  • Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a 'mitohormesis' mechanism involving reactive oxygen species and PGC-1.

    abstract:AIMS:Statins protect against cardiovascular-related mortality but induce skeletal muscle toxicity. To investigate mechanisms of statins, we tested the hypothesis that statins optimized cardiac mitochondrial function but impaired vulnerable skeletal muscle by inducing different level of reactive oxygen species (ROS). M...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehr224

    authors: Bouitbir J,Charles AL,Echaniz-Laguna A,Kindo M,Daussin F,Auwerx J,Piquard F,Geny B,Zoll J

    更新日期:2012-06-01 00:00:00

  • High-density lipoprotein, but not low-density lipoprotein cholesterol levels influence short-term prognosis after acute coronary syndrome: results from the MIRACL trial.

    abstract:AIMS:Patients with acute coronary syndrome (ACS) in the Myocardial Ischaemia Reduction with Aggressive Cholesterol Lowering (MIRACL) study had diminished cardiovascular events after 16 weeks of treatment of atorvastatin 80 mg daily. We determined whether plasma lipoproteins at baseline and then at 6 weeks after randomi...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/eurheartj/ehi186

    authors: Olsson AG,Schwartz GG,Szarek M,Sasiela WJ,Ezekowitz MD,Ganz P,Oliver MF,Waters D,Zeiher A

    更新日期:2005-05-01 00:00:00

  • Management and outcome of patients with established coronary artery disease: the Euro Heart Survey on coronary revascularization.

    abstract:AIMS:The purpose of the Euro Heart Survey Programme of the European Society of Cardiology is to evaluate to which extent clinical practice endorses existing guidelines as well as to identify differences in population profiles, patient management, and outcome across Europe. The current survey focuses on the invasive dia...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehi238

    authors: Lenzen MJ,Boersma E,Bertrand ME,Maier W,Moris C,Piscione F,Sechtem U,Stahle E,Widimsky P,de Jaegere P,Scholte op Reimer WJ,Mercado N,Wijns W,European Society of Cardiology.

    更新日期:2005-06-01 00:00:00

  • Multicentre, randomized comparison of two-stent and provisional stenting techniques in patients with complex coronary bifurcation lesions: the DEFINITION II trial.

    abstract:AIM:The present study aimed to assess the benefits of two-stent techniques for patients with DEFINITION criteria-defined complex coronary bifurcation lesions. METHODS AND RESULTS:In total, 653 patients with complex bifurcation lesions at 49 international centres were randomly assigned to undergo the systematic two-ste...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehaa543

    authors: Zhang JJ,Ye F,Xu K,Kan J,Tao L,Santoso T,Munawar M,Tresukosol D,Li L,Sheiban I,Li F,Tian NL,Rodríguez AE,Paiboon C,Lavarra F,Lu S,Vichairuangthum K,Zeng H,Chen L,Zhang R,Ding S,Gao F,Jin Z,Hong L,Ma L,We

    更新日期:2020-07-14 00:00:00

  • Amiodarone prophylaxis for atrial fibrillation of high-risk patients after coronary bypass grafting: a prospective, double-blinded, placebo-controlled, randomized study.

    abstract:AIMS:Atrial fibrillation (AF) occurs often in patients after coronary artery bypass grafting (CABG) and can result in increased morbidity and mortality. Previous studies using P-wave signal-averaged electrocardiogram (P-SAECG) have shown that patients with a longer filtered P-wave duration (FPD) have a high risk of AF ...

    journal_title:European heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/eurheartj/ehl082

    authors: Budeus M,Hennersdorf M,Perings S,Röhlen S,Schnitzler S,Felix O,Reimert K,Feindt P,Gams E,Lehmann N,Wieneke H,Sack S,Erbel R,Perings C

    更新日期:2006-07-01 00:00:00

  • Identification of post acute myocardial infarction patients with potential benefit from prophylactic treatment with amiodarone. A substudy of EMIAT (the European Myocardial Infarct Amiodarone Trial).

    abstract:AIMS:To perform a retrospective analysis of subgroups of patients enrolled into the European Myocardial Infarct Amiodarone Trial (EMIAT) in order to identify patients who might benefit from prophylactic amiodarone treatment and patients in whom amiodarone might be harmful. METHODS:Baseline characteristics of the 1486 ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1053/euhj.1997.0823

    authors: Janse MJ,Malik M,Camm AJ,Julian DG,Frangin GA,Schwartz PJ

    更新日期:1998-01-01 00:00:00

  • Predictors of major bleeding in acute coronary syndromes: the Global Registry of Acute Coronary Events (GRACE).

    abstract:AIMS:There have been no large observational studies attempting to identify predictors of major bleeding in patients with acute coronary syndromes (ACS), particularly from a multinational perspective. The objective of our study was thus to develop a prediction rule for the identification of patients with ACS at higher r...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/s0195-668x(03)00485-8

    authors: Moscucci M,Fox KA,Cannon CP,Klein W,López-Sendón J,Montalescot G,White K,Goldberg RJ

    更新日期:2003-10-01 00:00:00

  • Anti-anginal, electrophysiologic and hemodynamic effects of combined beta-blocker/calcium antagonist therapy.

    abstract::Nitrates and beta-blockers have been the mainstay in the therapy of chronic stable angina pectoris for many years. Since an important number of patients remains symptomatic, new potent anti-ischemic agents like the calcium antagonists fulfil a great clinical need. Combined therapy with beta-blockers and calcium antago...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/4.suppl_d.117

    authors: Vanhaleweyk GL,Serruys PW,Hugenholtz PG

    更新日期:1983-07-01 00:00:00

  • Effects of transdermal nitroglycerin in combination with an ACE inhibitor in patients with chronic stable angina pectoris.

    abstract::We have previously shown that transdermal nitroglycerin may induce an increase in the activity of the adrenergic and the renin-angiotensin-aldosterone systems (SRAA) in patients with chronic stable angina pectoris (SA); when the activation of these systems is more pronounced, the antianginal effect of this drug seems ...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1093/eurheartj/14.12.1701

    authors: Muiesan ML,Boni E,Castellano M,Beschi M,Cefis G,Cerri B,Verdecchia P,Porcellati C,Pollavini G,Agabiti-Rosei E

    更新日期:1993-12-01 00:00:00

  • Relationship of arterial stiffness and early mild diastolic heart failure in general middle and aged population.

    abstract:AIMS:The brachial-ankle pulse wave velocity (baPWV) has been recognized as a marker that reflects arterial stiffness. We conducted an investigation to evaluate whether baPWV is independently associated with early mild diastolic heart failure (DHF) in a general middle and aged population. METHODS AND RESULTS:From 1 Jul...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehq296

    authors: Kang S,Fan HM,Li J,Fan LY,Miao AY,Bao Y,Wu LZ,Zhu Y,Zhang DF,Liu ZM

    更新日期:2010-11-01 00:00:00

  • Unprotected left main revascularization in patients with acute coronary syndromes.

    abstract:AIMS:In acute coronary syndromes (ACS), the optimal revascularization strategy for unprotected left main coronary disease (ULMCD) has been little studied. The objectives of the present study were to describe the practice of ULMCD revascularization in ACS patients and its evolution over an 8-year period, analyse the pro...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehp353

    authors: Montalescot G,Brieger D,Eagle KA,Anderson FA Jr,FitzGerald G,Lee MS,Steg PG,Avezum A,Goodman SG,Gore JM,GRACE Investigators.

    更新日期:2009-10-01 00:00:00

  • Cardiovascular magnetic resonance in immune checkpoint inhibitor-associated myocarditis.

    abstract:AIMS:Myocarditis is a potentially fatal complication of immune checkpoint inhibitors (ICI). Sparse data exist on the use of cardiovascular magnetic resonance (CMR) in ICI-associated myocarditis. In this study, the CMR characteristics and the association between CMR features and cardiovascular events among patients with...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehaa051

    authors: Zhang L,Awadalla M,Mahmood SS,Nohria A,Hassan MZO,Thuny F,Zlotoff DA,Murphy SP,Stone JR,Golden DLA,Alvi RM,Rokicki A,Jones-O'Connor M,Cohen JV,Heinzerling LM,Mulligan C,Armanious M,Barac A,Forrestal BJ,Sullivan RJ,

    更新日期:2020-05-07 00:00:00

  • Leptin is an endothelial-independent vasodilator in humans with coronary artery disease: Evidence for tissue specificity of leptin resistance.

    abstract:AIMS:We sought to define the mechanisms and correlates of leptin's vascular actions in humans with coronary artery disease. METHODS AND RESULTS:In 131 patients (age 65.7+/-0.7 years mean+/-SEM), ex vivo vascular reactivity to leptin (10(-13)-10(-7) M) was assessed in saphenous vein (SV) rings. Leptin led to SV relaxat...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehi831

    authors: Momin AU,Melikian N,Shah AM,Grieve DJ,Wheatcroft SB,John L,El Gamel A,Desai JB,Nelson T,Driver C,Sherwood RA,Kearney MT

    更新日期:2006-10-01 00:00:00

  • Epidemiology of desmin and cardiac actin gene mutations in a european population of dilated cardiomyopathy.

    abstract:AIMS:Although dilated cardiomyopathy is the most frequent form of cardiomyopathy, its aetiology is still poorly understood. In about 20-30% of cases the disease is familial with a large predominance of autosomal dominant transmission. Ten different chromosomal loci have been described for autosomal dominant forms of di...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1053/euhj.2000.2245

    authors: Tesson F,Sylvius N,Pilotto A,Dubosq-Bidot L,Peuchmaurd M,Bouchier C,Benaiche A,Mangin L,Charron P,Gavazzi A,Tavazzi L,Arbustini E,Komajda M

    更新日期:2000-11-01 00:00:00

  • A clinical risk score of myocardial fibrosis predicts adverse outcomes in aortic stenosis.

    abstract:AIMS:Midwall myocardial fibrosis on cardiovascular magnetic resonance (CMR) is a marker of early ventricular decompensation and adverse outcomes in aortic stenosis (AS). We aimed to develop and validate a novel clinical score using variables associated with midwall fibrosis. METHODS AND RESULTS:One hundred forty-seven...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehv525

    authors: Chin CW,Messika-Zeitoun D,Shah AS,Lefevre G,Bailleul S,Yeung EN,Koo M,Mirsadraee S,Mathieu T,Semple SI,Mills NL,Vahanian A,Newby DE,Dweck MR

    更新日期:2016-02-21 00:00:00

  • Haemodynamic effects of frusemide and its influence on repetitive rapid volume loading in acute myocardial infarction.

    abstract::The haemodynamic effects of intravenous frusemide (1 mg/kg) were studied in 22 male patients with left ventricular failure following acute myocardial infarction. Radiographic pulmonary oedema was present in all patients and their average left heart filling pressure was 20 mmHg. Bolus injection of the drug was followed...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a061382

    authors: Nelson GI,Ahuja RC,Silke B,Okoli RC,Hussain M,Taylor SH

    更新日期:1983-10-01 00:00:00

  • Comparison of the effects of two doses of bisoprolol on exercise tolerance in exercise-induced stable angina pectoris.

    abstract::Recently, bisoprolol has been investigated regarding its effects on exercise tolerance and the duration of action in patients with coronary heart disease (CHD) following single oral administration. It appears, however, that the extent of effects of 5 mg bisoprolol is not fully established yet. Therefore, the effects o...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/eurheartj/8.suppl_m.31

    authors: de Muinck E,Wagner G,vd Ven LL,Lie KI

    更新日期:1987-12-01 00:00:00

  • Implantable cardioverter defibrillators for primary prevention of death in left ventricular dysfunction with and without ischaemic heart disease: a meta-analysis of 8567 patients in the 11 trials.

    abstract:Aims:Primary prevention implantable cardioverter defibrillators (ICDs) are established therapy for reducing mortality in patients with left ventricular systolic dysfunction and ischaemic heart disease (IHD). However, their efficacy in patients without IHD has been controversial. We undertook a meta-analysis of the tota...

    journal_title:European heart journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.1093/eurheartj/ehx028

    authors: Shun-Shin MJ,Zheng SL,Cole GD,Howard JP,Whinnett ZI,Francis DP

    更新日期:2017-06-07 00:00:00

  • Lesion morphology assessed by pre-interventional intravascular ultrasound does not predict the incidence of severe coronary artery dissections.

    abstract:AIMS:Coronary artery dissections are common findings following percutaneous transluminal coronary angioplasty and occur with an incidence of approximately 20% to 40%. The purpose of this study was to evaluate the impact of intravascular ultrasound for the prediction of severe dissections by pre-interventional analysis ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1053/euhj.1997.0799

    authors: Athanasiadis A,Haase KK,Wullen B,Treusch AW,Mahrholdt H,Voelker W,Baumbach A,Oberhoff M,Karsch KR

    更新日期:1998-06-01 00:00:00

  • A double-blind dose-response study of amlodipine in patients with stable angina pectoris.

    abstract::Sixty patients (31 male, 29 female) were studied in a 4-week double-blind parallel dose-response study. Patients received amlodipine 1.25 mg (n = 12), 2.5 mg (n = 12), 5 mg (n = 12), 10 mg (n = 12) or placebo (n = 12) once a day. Anti-anginal efficacy was assessed by sequential treadmill testing 24 h post-dose, freque...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/oxfordjournals.eurheartj.a059864

    authors: Cocco G,Alfiero R

    更新日期:1991-02-01 00:00:00

  • Sudden cardiac death while taking amiodarone therapy: the role of abnormal repolarization.

    abstract::Torsade de pointes may occur as a complication of amiodarone therapy. We report a patient receiving amiodarone who was resuscitated from cardiovascular collapse and documented ventricular fibrillation. At subsequent electrophysiology study, while the patient was taking amiodarone therapy, monophasic action potentials ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a059849

    authors: Morgan JM,Lopes A,Rowland E

    更新日期:1991-10-01 00:00:00