Leptin is an endothelial-independent vasodilator in humans with coronary artery disease: Evidence for tissue specificity of leptin resistance.

abstract：AIMS:Monocytes are critical mediators of healing following acute myocardial infarction (AMI), making them an interesting target to improve myocardial repair. The purpose of this study was a gain of insight into the source and recruitment of monocytes following AMI in humans. METHODS AND RESULTS:Post-mortem tissue spec...

journal_title：European heart journal

authors： van der Laan AM,Ter Horst EN,Delewi R,Begieneman MP,Krijnen PA,Hirsch A,Lavaei M,Nahrendorf M,Horrevoets AJ,Niessen HW,Piek JJ

更新日期：2014-02-01 00:00:00

abstract：:Diastolic heart disease is common and appears to be the primary abnormality in a substantial proportion of all patients with CHF. The epidemiology and natural history of the condition appears different to that of systolic heart failure, resulting in significant morbidity although contributing little to overall mortali...

journal_title：European heart journal

authors： Wheeldon NM,Clarkson P,MacDonald TM

更新日期：1994-12-01 00:00:00

abstract：AIMS:Release of progenitor cells is observed during inflammatory conditions and contributes to neovascularization. We, therefore, sought to investigate the relationship of circulating progenitor cells and interleukin (IL)-8 in acute myocardial infarction (AMI). METHODS AND RESULTS:From patients with stable angina and ...

journal_title：European heart journal

authors： Schömig K,Busch G,Steppich B,Sepp D,Kaufmann J,Stein A,Schömig A,Ott I

更新日期：2006-05-01 00:00:00

abstract：:This study analyses the immediate outcome and the risk of recurrent restenosis in patients who, at the time of repeat coronary angioplasty for a first restenosis, had unstable (n = 50), 19%) or stable (n = 218, 81%) angina. Successful angioplasty was accomplished in 250 (93%) patients, 222 (89%) of whom had follow-up ...

journal_title：European heart journal

authors： Bauters C,Lablanche JM,McFadden EP,Leroy F,Bertrand ME

更新日期：1993-02-01 00:00:00

abstract：:In single vessel disease angioplasty can replace surgery in the majority of patients. In cases of recurrence at the site of angioplasty or in the case of progression elsewhere, a second intervention can be performed. Thus, in the majority of patients surgery can be replaced; in the minority it can be delayed. In patie...

journal_title：European heart journal

authors： Kaltenbach M

更新日期：1987-09-01 00:00:00

abstract：:To determine the neurohormonal response to angiotensin-converting enzyme (ACE) inhibition after acute myocardial infarction, 36 patients presenting within 6 h of the onset of chest pain were studied in a single regional cardiology service. In this double-blind study, 13 patients were randomized to receive captopril, 1...

journal_title：European heart journal

authors： Foy SG,Crozier IG,Richards AM,Nicholls MG,Turner JG,Frampton CM,Ikram H

更新日期：1995-06-01 00:00:00

abstract：AIMS:Recent randomized trials suggest that intensive glycaemic control fails to reduce heart failure-related events in patients with diabetes. The molecular cues underlying persistent myocardial damage despite normoglycaemia restoration remain elusive. MicroRNAs (miRNAs), a class of small non-coding RNAs, orchestrate t...

journal_title：European heart journal

authors： Costantino S,Paneni F,Lüscher TF,Cosentino F

更新日期：2016-02-07 00:00:00

abstract：:Two patients with myocardial bridging of the left anterior descending coronary artery associated with myocardial infarction are described. One of them died from acute cerebral emboli related to cardiac thrombosis in a left ventricular aneurysm. The other died suddenly while sleeping. Both patients were found to have a...

journal_title：European heart journal

authors： Bestetti RB,Costa RS,Zucolotto S,Oliveira JS

更新日期：1989-06-01 00:00:00

abstract：:The management of left ventricular hypertrophy (LVH) presupposes that the patient is identified by echocardiography and is carefully evaluated for risk stratification, taking into consideration possible associated complications. The role of non-pharmacological treatment is limited, except in obese patients. Drug treat...

journal_title：European heart journal

authors： de Divitiis O,Celentano A,De Simone G,Di Somma S,Galderisi M,Liguori V,de Divitiis M,Petitto M

更新日期：1993-07-01 00:00:00

abstract：AIMS:Anecdotal observations suggest that sub-clinical electrophysiological manifestations of arrhythmogenic right ventricular cardiomyopathy (ARVC) develop before detectable structural changes ensue on cardiac imaging. To test this hypothesis, we investigated a murine model with conditional cardiac genetic deletion of ...

journal_title：European heart journal

authors： Gomes J,Finlay M,Ahmed AK,Ciaccio EJ,Asimaki A,Saffitz JE,Quarta G,Nobles M,Syrris P,Chaubey S,McKenna WJ,Tinker A,Lambiase PD

更新日期：2012-08-01 00:00:00

abstract：AIM:Short-term psychological stress is associated with an immediate physiological response and may be associated with a transiently higher risk of cardiovascular events. The aim of this study was to determine whether brief episodes of anger trigger the onset of acute myocardial infarction (MI), acute coronary syndromes...

journal_title：European heart journal

authors： Mostofsky E,Penner EA,Mittleman MA

更新日期：2014-06-01 00:00:00

abstract：:A group of investigators met for two days in Santorini, Greece, to discuss progress in the field of identification and treatment of high risk/vulnerable atherosclerotic plaques and patients. Many differences in the manner in which terms are being utilized were noted. It was recognized that increased understanding of t...

journal_title：European heart journal

authors： Schaar JA,Muller JE,Falk E,Virmani R,Fuster V,Serruys PW,Colombo A,Stefanadis C,Ward Casscells S,Moreno PR,Maseri A,van der Steen AF

更新日期：2004-06-01 00:00:00

abstract：:Among 369 patients with native valve infective endocarditis observed during a 14-year period, 17 were related to S: pneumoniae. Fourteen of them were observed in the last 7 years. At the time of admission 13 exhibited purulent meningitis, 6 of them being comatose. An apparent portal of entry was present in 13 patients...

journal_title：European heart journal

authors： Wolff M,Regnier B,Witchitz S,Gibert C,Amoudry C,Vachon F

更新日期：1984-10-01 00:00:00

abstract：:We have evaluated overall and cardiac sympathetic activity in 47 patients undergoing coronary angiography, 27 with stable angina of at least 3 months duration, and 20 with unstable ischaemic symptoms within this period. Cardiac and overall sympathetic activity were assessed using radiotracer noradrenaline kinetic tech...

journal_title：European heart journal

authors： McCance AJ,Thompson PA,Forfar JC

更新日期：1993-06-01 00:00:00

abstract：AIMS:We hypothesized that chronic heart failure as a model of systemic hypoxia may result in systemic inflammation. The signs of a systemic inflammatory response should disappear after successful mechanical circulatory support using biventricular assist device systems. METHODS AND RESULTS:Plasma levels of cytokines (I...

journal_title：European heart journal

authors： Hasper D,Hummel M,Kleber FX,Reindl I,Volk HD

更新日期：1998-05-01 00:00:00

abstract：:As regional wall motion abnormality (RWA) is the first sign of ischaemia, transoesophageal echocardiography was evaluated as a monitoring device in 51 patients undergoing abdominal aortic surgery. Wall motion of the entire left ventricular wall (nine segments) was semiquantitatively evaluated 15 min before and after a...

journal_title：European heart journal

authors： Koolen JJ,Visser CA,Reichert SL,Jaarsma WJ,Kromhout JG,van Wezel HB,Dunning AJ

更新日期：1992-08-01 00:00:00

abstract：:We assessed the incremental effect of cardiac catheterization upon the management of 93 adult patients with aortic and/or mitral valve disease, referred for surgical consideration. There were 52 patients with aortic valve disease, 29 with mitral valve disease and 12 with aortic and mitral valve disease. Prior to cardi...

journal_title：European heart journal

authors： Leitch JW,Mitchell AS,Harris PJ,Fletcher PJ,Bailey BP

更新日期：1991-05-01 00:00:00

abstract：AIMS:Cardiac biomarkers are routinely elevated after uncomplicated cardiac surgery to levels considered diagnostic of myocardial infarction in ambulatory populations. We investigated the diagnostic power of electrocardiogram (ECG) and cardiac biomarker criteria to predict clinically relevant myocardial injury using ben...

journal_title：European heart journal

authors： Muehlschlegel JD,Perry TE,Liu KY,Nascimben L,Fox AA,Collard CD,Avery EG,Aranki SF,D'Ambra MN,Shernan SK,Body SC,CABG Genomics Investigators.

更新日期：2009-07-01 00:00:00

abstract：:The purpose of this study was to evaluate the accuracy of adenosine Tc-99m sestamibi single photon emission computed tomography (SPECT) in the detection of jeopardized myocardium early after acute myocardial infarction. Coronary arteriography and myocardial scintigraphy were performed in 50 consecutive patients with a...

journal_title：European heart journal

authors： Claeys MJ,Vrints CJ,Krug B,Bosmans JM,Blockx PP,Bossaert LL,Snoeck JP

更新日期：1995-09-01 00:00:00

abstract：AIMS:Increased cardiovascular morbidity is manifested a long time after the repair of aortic coarctation (CoA). By way of impaired flow-mediated vasodilation (FMD) and increased intima media thickness (IMT), surrogate parameters of atherosclerosis, cardiovascular risk factors (RFs) can be correlated with early vascular...

journal_title：European heart journal

authors： Meyer AA,Joharchi MS,Kundt G,Schuff-Werner P,Steinhoff G,Kienast W

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:We evaluated prognostic value at 6 months of residual pulmonary vascular obstruction (RPVO) measured before discharge in patients with intermediate- or high-risk pulmonary embolism (PE). METHODS AND RESULTS:Prospective registry including 416 consecutive patients with intermediate- or high-risk PE who surviv...

journal_title：European heart journal

authors： Meneveau N,Ider O,Seronde MF,Chopard R,Davani S,Bernard Y,Schiele F

更新日期：2013-03-01 00:00:00

abstract：:Transient ischaemic episodes, defined as chest pain with ST segment elevation resolving in less than 15 min, have been encountered in 18 out of 130 patients during or in the 12h following percutaneous transluminal angioplasty (PTCA). During PTCA, ischaemic episodes occurred in 11 patients (8.5%) along with complete co...

journal_title：European heart journal

authors： Danchin N,Cuilliere M,Cherrier F

更新日期：1984-05-01 00:00:00

abstract：Aims:Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by right ventricular myocardial replacement and life-threatening ventricular arrhythmias. Desmosomal gene mutations are sometimes identified, but clinical and genetic diagnosis remains challenging. Desmosomal skin disorders can be caused by de...

journal_title：European heart journal

authors： Chatterjee D,Fatah M,Akdis D,Spears DA,Koopmann TT,Mittal K,Rafiq MA,Cattanach BM,Zhao Q,Healey JS,Ackerman MJ,Bos JM,Sun Y,Maynes JT,Brunckhorst C,Medeiros-Domingo A,Duru F,Saguner AM,Hamilton RM

更新日期：2018-11-21 00:00:00

abstract：AIMS:The impact on mortality outcomes of beta-blockers and calcium blockers in post-myocardial infarction (MI) has been suggested to be related to resting heart rate (HR) reduction. A meta-regression of randomized clinical trials was carried out to assess this relationship using weighted meta-regression of logarithm of...

journal_title：European heart journal

authors： Cucherat M

更新日期：2007-12-01 00:00:00

abstract：Aims:The burden of cardiovascular disease is increasing worldwide, which has to be reflected by cardiovascular (CV) research in Europe. CardioScape, a FP7 funded project initiated by the European Society of Cardiology (ESC), identified where CV research is performed, how it is funded and by whom. It could be transforme...

journal_title：European heart journal

authors： Pries AR,Naoum A,Habazettl H,Dunkel M,Preissner R,Coats CJ,Tornada A,Orso F,Van de Werf F,Wood DA,CardioScape steering committee.,Van de Werf F,Wood DA,O'Kelly S,Craven J,Coats A,Sipido K,De Backer D,Wallentin L,Has

更新日期：2018-07-01 00:00:00

abstract：:Spectral turbulence analysis of the signal-averaged electrocardiogram is a new method for identifying patients prone to sustained monomorphic ventricular tachycardia. In contrast to analysis in the time domain, it has been claimed to be applicable in patients with bundle branch block. The aim of this study was to asse...

journal_title：European heart journal

authors： Englund A,Andersson M,Bergfeldt L

更新日期：1995-12-01 00:00:00

abstract：:Treatment of 8 hypertensive elderly subjects with atenolol or with labetalol did not affect exercise performance, except after the development of circulatory congestion in 1 patient. Treatment with beta blockers did not alter the response to an exercise training programme in 15 elderly patients with ischaemic heart di...

journal_title：European heart journal

authors： Fagard R,Reybrouck T,Vanhees L,Cattaert A,Vanmeenen T,Grauwels R,Amery A

更新日期：1984-11-01 00:00:00

abstract：AIMS:The aim of this study was to assess whether perioperative N-acetylcysteine (NAC), an antioxidant, prevents acute renal injury (ARI) after cardiac surgery. METHODS AND RESULTS:We performed a systematic review of randomized controlled trials (RCTs) of NAC in adult cardiac surgery patients. The RCTs were identified ...

journal_title：European heart journal

authors： Adabag AS,Ishani A,Bloomfield HE,Ngo AK,Wilt TJ

更新日期：2009-08-01 00:00:00

abstract：:I.S.A.M. was a prospective, placebo-controlled, double-blind multicentre trial of high-dose short-term intravenous streptokinase in acute myocardial infarction (AMI) within 6 h of the onset of symptoms. Determination of left ventricular ejection fraction (LVEF) by radionuclide ventriculography was performed 1 and 7 mo...

journal_title：European heart journal

authors： Voth E,Tebbe U,Schicha H,Neumann P,Schröder R,Neuhaus KL,Emrich D

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND:Sixteen cases of sudden unexpected cardiac death, 15 males and one female, are known to have occurred among young Swedish orienteers from 1979 to 1992, of which seven cases occurred between 1989 and 1992. This is considered to be indicative of an increased death rate. RESULTS:Histopathological evaluation sh...

journal_title：European heart journal

authors： Wesslén L,Påhlson C,Lindquist O,Hjelm E,Gnarpe J,Larsson E,Baandrup U,Eriksson L,Fohlman J,Engstrand L,Linglöf T,Nyström-Rosander C,Gnarpe H,Magnius L,Rolf C,Friman G

更新日期：1996-06-01 00:00:00