Systemic inflammation in patients with heart failure.

abstract：AIMS:To assess the prognostic significance of infarct core tissue characteristics using cardiac magnetic resonance (CMR) imaging in survivors of acute ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS:We performed an observational prospective single centre cohort study in 300 reperfused STEMI patients (m...

journal_title：European heart journal

authors： Carrick D,Haig C,Rauhalammi S,Ahmed N,Mordi I,McEntegart M,Petrie MC,Eteiba H,Hood S,Watkins S,Lindsay M,Mahrous A,Ford I,Tzemos N,Sattar N,Welsh P,Radjenovic A,Oldroyd KG,Berry C

更新日期：2016-04-01 00:00:00

abstract：AIMS:Sirolimus- and paclitaxel-eluting stents effectively reduce restenosis in small coronary vessels. The relative efficacy of these drug-eluting stents in this high-risk subset is not known. METHODS AND RESULTS:A total of 360 patients undergoing percutaneous coronary intervention for de novo lesions in native corona...

journal_title：European heart journal

authors： Mehilli J,Dibra A,Kastrati A,Pache J,Dirschinger J,Schömig A,Intracoronary Drug-Eluting Stenting to Abrogate Restenosis in Small Arteries (ISAR-SMART 3) Study Investigators.

更新日期：2006-02-01 00:00:00

abstract：AIMS:We investigated the prevalence of prior myocardial infarction (MI) and incidence of ischaemic cardiovascular (CV) events among atrial fibrillation (AF) patients. METHODS AND RESULTS:In ROCKET AF, 14 264 patients with nonvalvular AF were randomized to rivaroxaban or warfarin. The key efficacy outcome for these ana...

journal_title：European heart journal

authors： Mahaffey KW,Stevens SR,White HD,Nessel CC,Goodman SG,Piccini JP,Patel MR,Becker RC,Halperin JL,Hacke W,Singer DE,Hankey GJ,Califf RM,Fox KA,Breithardt G,ROCKET AF Investigators.

更新日期：2014-01-01 00:00:00

abstract：AIMS:Prophylactic administration of N-acetylcysteine (NAC) (600mg orally twice daily), along with hydration, prevents contrast agent-associated nephrotoxicity (CAN) induced by a low dose of non-ionic, low-osmolality contrast dye. We tested whether a double dose of NAC is more effective to prevent CAN. METHODS AND RESU...

journal_title：European heart journal

authors： Briguori C,Colombo A,Violante A,Balestrieri P,Manganelli F,Paolo Elia P,Golia B,Lepore S,Riviezzo G,Scarpato P,Focaccio A,Librera M,Bonizzoni E,Ricciardelli B

更新日期：2004-02-01 00:00:00

abstract：AIMS:We describe a new strategic stepwise mapping approach for fast and accurate identification and ablation of ectopic atrial foci using an electroanatomic mapping system. METHODS AND RESULTS:Mapping procedures started with the acquisition of four points at the superior/septal part of the tricuspid annulus. According...

journal_title：European heart journal

authors： Wetzel U,Hindricks G,Schirdewahn P,Dorszewski A,Fleck A,Heinke F,Kottkamp H

更新日期：2002-09-01 00:00:00

abstract：AIMS:The aim of this study was to determine the outcome benefits in those originally assigned atorvastatin in the Anglo-Scandinavian Cardiac Outcomes Trial-8 years after closure of the lipid-lowering arm (LLA) of the trial (ASCOT-LLA) among the U.K. population. METHODS AND RESULTS:ASCOT-LLA was a factorially designed ...

journal_title：European heart journal

authors： Sever PS,Chang CL,Gupta AK,Whitehouse A,Poulter NR,ASCOT Investigators.

更新日期：2011-10-01 00:00:00

abstract：:Between 1968 and 1984, 78 patients (mean age 43, range 14 to 65 years) underwent combined aortic, mitral and tricuspid surgery (22 triple valve replacements, 56 aortic valve replacements with tricuspid conservative surgery and mitral valve replacement (N = 48), or commissuroplasty (N = 8). Pre-operative consequences o...

journal_title：European heart journal

authors： Michel PL,Houdart E,Ghanem G,Badaoui G,Hage A,Acar J

更新日期：1987-05-01 00:00:00

abstract：:The endothelins are a family of three widely expressed 21 amino acid peptides. Apart from the ability to constrict vascular smooth muscle, they have numerous other potent effects, from enhancing mitogenesis to influencing nervous function. The pathway of their production involves the initial synthesis of a predominant...

journal_title：European heart journal

authors： Warner TD

更新日期：1993-11-01 00:00:00

abstract：:Experience accumulated from several large trials strongly suggests that beta-blockers should be used for the management of chronic heart failure[87]. It is appropriate to add beta-blockade to conventional therapy such as diuretics, ACE inhibitors and digoxin, as this was the approach used in the major trials. It is ap...

journal_title：European heart journal

authors： Cleland JG,Bristow MR,Erdmann E,Remme WJ,Swedberg K,Waagstein F

更新日期：1996-11-01 00:00:00

abstract：:The early termination of clinical trials, for either benefit or harm, often generates undue enthusiasm or alarm. The enhanced publicity attending early termination of a trial promotes inappropriate interpretations because of the inherent difficulty of a prompt and comprehensive data review. Furthermore, the process of...

journal_title：European heart journal

authors：

更新日期：1994-06-01 00:00:00

abstract：:The efficacy of sustained-release diltiazem (diltiazem-SR) 120 mg b.i.d. was compared with metoprolol 100 mg b.i.d. in 12 patients with stable angina. Following a 1-week placebo period, patients received diltiazem-SR or metoprolol in two 3-week treatment periods, in a randomized double-blind crossover design. Total ex...

journal_title：European heart journal

authors： Posma JL,van Dijk RB,Lie KI

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Antiarrhythmic drugs are still used for the treatment of ventricular tachyarrhythmias, in combination with implantable cardioverter-defibrillators or without them. AIM OF THE STUDY:In a double-blind randomized crossover design, the short- and long-term efficacy and safety of oral dofetilide or oral sotalol ...

journal_title：European heart journal

authors： Boriani G,Lubinski A,Capucci A,Niederle R,Kornacewicz-Jack Z,Wnuk-Wojnar AM,Borggrefe M,Brachmann J,Biffi M,Butrous GS,Ventricular Arrhythmias Dofetilide Investigators.

更新日期：2001-12-01 00:00:00

abstract：:The effects of dexamethasone on cultured rat beating heart cells experimentally infected with coxsackievirus B2 were investigated at an early stage (1-3 days) post challenge. Changes in the release of the cardiac enzyme, aspartate amino-transferase (AST), beating %, cytopathic effect (CPE), virus titre, ultrastructure...

journal_title：European heart journal

authors： Yang YZ,Yuan WL,Guo Q,Gong ZX,Zhow TS,Shen JY,Chen HZ

更新日期：1991-08-01 00:00:00

abstract：:In a pilot study, a prophylactic regimen including ciprofloxacin and amphotericin B was applied in 102 consecutive patients on artificial respiration for greater than or equal to 5 days to prevent respiratory tract infection with aerobic Gram-negative bacilli. Ciprofloxacin was given twice a day, as 500 mg through a g...

journal_title：European heart journal

authors： Haverkorn MJ

更新日期：1989-12-01 00:00:00

abstract：:The advent of platelet membrane glycoprotein (GP) IIb/IIIa inhibitors has changed the landscape of interventional cardiology. Given the commercial availability of abciximab and expected regulatory approvals for other receptor blockers, defining appropriate use of these agents in the interventional setting is mandated....

journal_title：European heart journal

authors： Chronos N,Vahanian A,Betriu A,Emanuelsson H,Goldberg S,Gulba D,van Hout BA

更新日期：1998-04-01 00:00:00

abstract：AIMS:To test the hypothesis that increasing age in patients presenting with high-risk non-ST-segment elevation acute coronary syndromes (NSTE-ACS) does not adversely influence the benefit of an early invasive strategy on major adverse events at 6 months. METHODS AND RESULTS:We report clinical outcomes in young (<70), ...

journal_title：European heart journal

authors： Devlin G,Gore JM,Elliott J,Wijesinghe N,Eagle KA,Avezum A,Huang W,Brieger D,GRACE Investigators.

更新日期：2008-05-01 00:00:00

abstract：:Myocardial relaxation is an energy-dependent process. Indeed, adenosine triphosphate (ATP) is required to pump free myoplasmic calcium back into the sarcoplasmic reticulum. It is also necessary to extrude the calcium ions which enter the cell during the plateau phase of the action potential. The calcium-sodium exchang...

journal_title：European heart journal

authors： Pouleur H

更新日期：1990-05-01 00:00:00

abstract：:The concentration of cholesterol in peripheral lymph is roughly one tenth of that in the blood plasma of the same subject. In lymph, there is virtually no very low density lipoprotein (VLDL), probably due to low permeability of the vascular endothelium for particles of this size. More than 95% of apo B-containing lipo...

journal_title：European heart journal

authors： Reichl D

更新日期：1990-08-01 00:00:00

abstract：:The class III antiarrhythmic drug dofetilide is known to prolong action potential duration by specific blockade of the delayed rectifier potassium channel Ik. As dofetilide is likely to be used in the treatment of atrial arrhythmias it is important to determine the relative sensitivity of the atrium and ventricle in m...

journal_title：European heart journal

authors： Sedgwick ML,Dalrymple I,Rae AP,Cobbe SM

更新日期：1995-11-01 00:00:00

abstract：:Human cytomegalovirus (CMV) can persist in many organs after primary infection. Not only is it suspected to cause morbidity during reactivation in patients under immunosuppression, but it may also induce long-term latency by chronic disease, e.g. in the myocardium. Endomyocardial biopsies of 27 patients with active my...

journal_title：European heart journal

authors： Schönian U,Crombach M,Maser S,Maisch B

更新日期：1995-12-01 00:00:00

abstract：AIMS:The relative benefits of computed tomography coronary angiography (CTCA)-guided management in women and men with suspected angina due to coronary heart disease (CHD) are uncertain. METHODS AND RESULTS:In this post hoc analysis of an open-label parallel-group multicentre trial, we recruited 4146 patients referred ...

journal_title：European heart journal

authors： Mangion K,Adamson PD,Williams MC,Hunter A,Pawade T,Shah ASV,Lewis S,Boon NA,Flather M,Forbes J,McLean S,Roditi G,van Beek EJR,Timmis AD,Newby DE,McAllister DA,Berry C

更新日期：2020-04-01 00:00:00

abstract：AIMS:To determine what proportion of patients with heart failure are eligible for cardiac resynchronization therapy (CRT). METHODS AND RESULTS:Eligibility criteria from the trials establishing the efficacy of CRT were applied to two prospective cohorts: the first enrolled patients with newly diagnosed heart failure di...

journal_title：European heart journal

authors： McAlister FA,Tu JV,Newman A,Lee DS,Kimber S,Cujec B,Armstrong PW

更新日期：2006-02-01 00:00:00

abstract：AIMS:Non-vitamin K antagonist oral anticoagulants (NOACs) require dose reductions according to patient or clinical factors for patients with atrial fibrillation (AF). In this meta-analysis, we aimed to assess outcomes with reduced-dose NOACs when given as pre-specified in pivotal trials. METHODS AND RESULTS:Aggregated...

journal_title：European heart journal

authors： Wang KL,Lopes RD,Patel MR,Büller HR,Tan DS,Chiang CE,Giugliano RP

更新日期：2019-05-14 00:00:00

abstract：:We assessed the incremental effect of cardiac catheterization upon the management of 93 adult patients with aortic and/or mitral valve disease, referred for surgical consideration. There were 52 patients with aortic valve disease, 29 with mitral valve disease and 12 with aortic and mitral valve disease. Prior to cardi...

journal_title：European heart journal

authors： Leitch JW,Mitchell AS,Harris PJ,Fletcher PJ,Bailey BP

更新日期：1991-05-01 00:00:00

abstract：:A 22-year-old man who engaged in intense and regular physical exercise complained of atypical chest pain. The only remarkable abnormality found in the routine clinical work-up was a left posterior hemiblock. The echocardiogram and the magnetic resonance imaging (MRI) study showed a tumour in the posterior and superior...

journal_title：European heart journal

authors： Cola H,Hoffman R,Borrega NG,Lazzari JO

更新日期：1992-04-01 00:00:00

abstract：:Orally active angiotensin converting enzyme (ACE) inhibitors have been successfully used in the treatment of congestive heart failure and hypertension. However, adverse skin reactions, such as angioneurotic oedema have been reported following such medication. Furthermore, these drugs have been associated with a persis...

journal_title：European heart journal

authors： Andersson RG,Persson K

更新日期：1994-08-01 00:00:00

abstract：:Recent studies have illustrated that in addition to the well known risk factors, such as lipoproteins, smoking, hypertension, there are others that cause atherosclerosis and myocardial infarction. Our knowledge of atherosclerotic lesions has increased. We now know that atherosclerotic changes are due to inflammatory c...

journal_title：European heart journal

authors： Nieminen MS,Mattila K,Valtonen V

更新日期：1993-12-01 00:00:00

abstract：AIMS:In experimental studies the recovery of pressure distal to stenotic valve orifices has been well described. We evaluated the extent, determinants, and clinical importance of pressure recovery in patients with aortic valve stenosis. METHODS AND RESULTS:The study was performed in 37 patients with aortic valve steno...

journal_title：European heart journal

authors： Schöbel WA,Voelker W,Haase KK,Karsch KR

更新日期：1999-09-01 00:00:00

abstract：:Nitrates are beneficial because they combine coronary and noncoronary effects. They have proven clinical efficacy, relieving symptoms and documented evidence of ischaemia. They can be given to patients by multiple routes and can be easily combined with other anti-ischaemic drugs including aspirin, heparin, calcium ant...

journal_title：European heart journal

authors： Conti CR

更新日期：1991-05-01 00:00:00

abstract：:In myocarditis an antigen-specific immune response to cardiac epitopes has been demonstrated by several investigators. In 25 patients with histologically proven myocarditis, autoantibodies to cardiac tissue were observed in 65% by immunofluorescence assay. By immunoblot analysis 46% of sera reacted with cardiac tissue...

journal_title：European heart journal

authors： Pankuweit S,Lottspeich F,Maisch B

更新日期：1995-12-01 00:00:00