Classification and characterization of cardiac isomyosins.

abstract：:Left ventricular performance at rest and during supine symptom-limited exercise was determined by radionuclide ventriculography (RNV) in 65 subjects of the age of 65 years or older. Eleven subjects had no evidence of coronary artery disease (CAD) by history or submaximal stress ECG. In this control group left ventricu...

journal_title：European heart journal

authors： Pichler M,Mostbeck G,Fridrich L,Eghbalian F,Gassner A

更新日期：1984-11-01 00:00:00

abstract：AIM:Unstable coronary artery disease (CAD) is a multifactorial disease involving both thrombotic and inflammatory processes. We have assessed the time-course and the influence of thrombin inhibitors on changes in fibrinogen and C-reactive protein levels, and their relation to myocardial ischaemia in unstable CAD. METH...

journal_title：European heart journal

authors： Oldgren J,Wallentin L,Grip L,Linder R,Nørgaard BL,Siegbahn A

更新日期：2003-01-01 00:00:00

abstract：:This report of an ESC Study Group reviews current knowledge on myocardial hibernation and relevant imaging techniques, and provides an algorithm for investigation and management when a patient presents with ischaemic left ventricular dysfunction. It covers the definitions of myocardial viability, stunning and hibernat...

journal_title：European heart journal

authors： Underwood SR,Bax JJ,vom Dahl J,Henein MY,Knuuti J,van Rossum AC,Schwarz ER,Vanoverschelde JL,van der Wall EE,Wijns W,Study Group of the European Society of Cardiology.

更新日期：2004-05-01 00:00:00

abstract：AIMS:Evidence is accumulating that inflammation plays a role in the pathophysiology of heart failure. Lipoprotein-associated phospholipase A2 (Lp-PLA2) has pro-inflammatory properties. We investigated whether Lp-PLA2 activity is associated with heart failure. METHODS AND RESULTS:Lp-PLA2 activity was determined in a ra...

journal_title：European heart journal

authors： van Vark LC,Kardys I,Bleumink GS,Knetsch AM,Deckers JW,Hofman A,Stricker BH,Witteman JC

更新日期：2006-10-01 00:00:00

abstract：AIMS:Atrial fibrillation (AF) is the most frequent arrhythmia in humans. Rare familial forms exist. Recent evidence indicates a genetic susceptibility to common forms of AF. The alpha-subunit of the myocardial I(Kr)-channel, encoded by the KCNH2 gene, is crucial to ventricular and atrial repolarization. Patients with m...

journal_title：European heart journal

authors： Sinner MF,Pfeufer A,Akyol M,Beckmann BM,Hinterseer M,Wacker A,Perz S,Sauter W,Illig T,Näbauer M,Schmitt C,Wichmann HE,Schömig A,Steinbeck G,Meitinger T,Kääb S

更新日期：2008-04-01 00:00:00

abstract：:A time-domain signal-averaged ECG was performed in 52 patients with arrhythmogenic right ventricular dysplasia (ARVD) proven by angiography, in 45 control subjects with normal hearts, and in 132 patients with various types of ventricular arrhythmias and no evidence of cardiac disease during routine cardiac examination...

journal_title：European heart journal

authors： Leclercq JF,Coumel P

更新日期：1993-09-01 00:00:00

abstract：:Five patients with recurrent tachycardias exhibiting right bundle branch block with left axis deviation were referred for investigation. In each case, a supraventricular mechanism was suspected. During sinus rhythm the QRS morphology and axis (-10 to +60 degrees) and HV intervals were normal. Tachycardia was initiated...

journal_title：European heart journal

authors： Ward DE,Nathan AW,Camm AJ

更新日期：1984-11-01 00:00:00

abstract：:The implementation of molecular biological approaches has led to the discovery of single genetic variations that contribute to the development of cardiac failure. In the present review, the characteristics that are invariably associated with the development of failure in experimental animals and clinical studies are d...

journal_title：European heart journal

authors： Lips DJ,deWindt LJ,van Kraaij DJ,Doevendans PA

更新日期：2003-05-01 00:00:00

abstract：AIM:Ventricular fibrosis is promoted by many effectors that chronically activate phospholipase D (PLD), and induces cardiac dysfunction and heart failure in cardiovascular diseases. Since ethanolamine is a product of PLD, we hypothesised that an administration of an analogue of ethanolamine, N-methylethanolamine (MEA),...

journal_title：European heart journal

authors： Yamamoto K,Takahashi Y,Mano T,Sakata Y,Nishikawa N,Yoshida J,Oishi Y,Hori M,Miwa T,Inoue S,Masuyama T

更新日期：2004-07-01 00:00:00

abstract：:We describe a patient with a large intramyocardial hydatid cyst lying in the postero-lateral segment of the left ventricle near the atrioventricular groove level which ruptured into the pericardial sac, resulting in cardiac tamponade. Cross-sectional echocardiographic examination from a modified four-chamber apical vi...

journal_title：European heart journal

authors： De Martini M,Nador F,Binda A,Arpesani A,Odero A,Lotto A

更新日期：1988-07-01 00:00:00

abstract：:Increased arteriolar tone is the pathophysiological hallmark of essential hypertension and is determined by the intracellular free calcium concentration in the vascular smooth muscle cell. Calcium influx is an important determinant of vasoconstriction and excess calcium influx-dependent vasoconstriction has been shown...

journal_title：European heart journal

authors： Erne P,Conen D,Kiowski W,Bolli P,Müller FB,Bühler FR

更新日期：1987-11-01 00:00:00

abstract：AIMS:Obesity is a recognized risk factor for atrial fibrillation (AF), partly because of the association between body mass index (BMI) and atrial volume. We aimed to determine whether other factors relating to body size were related to AF. METHODS AND RESULTS:Data were derived from a random population sample of 6903 m...

journal_title：European heart journal

authors： Rosengren A,Hauptman PJ,Lappas G,Olsson L,Wilhelmsen L,Swedberg K

更新日期：2009-05-01 00:00:00

abstract：:We have previously shown that transdermal nitroglycerin may induce an increase in the activity of the adrenergic and the renin-angiotensin-aldosterone systems (SRAA) in patients with chronic stable angina pectoris (SA); when the activation of these systems is more pronounced, the antianginal effect of this drug seems ...

journal_title：European heart journal

authors： Muiesan ML,Boni E,Castellano M,Beschi M,Cefis G,Cerri B,Verdecchia P,Porcellati C,Pollavini G,Agabiti-Rosei E

更新日期：1993-12-01 00:00:00

abstract：AIM:To describe the relative impact on survival of the delay from estimated time of collapse to call for an ambulance among patients who suffer from a bystander witnessed out of hospital cardiac arrest of a cardiac aetiology. METHODS:A majority of all ambulance organizations in Sweden (covering 85% of Sweden inhabitan...

journal_title：European heart journal

authors： Herlitz J,Engdahl J,Svensson L,Young M,Angquist KA,Holmberg S

更新日期：2003-10-01 00:00:00

abstract：:We now have conclusive data that ACE inhibitors reduce mortality, morbidity, and symptoms in patients with low ejection fraction and/or heart failure. Therefore, ACE inhibitors should be routinely used in all such patients, as long as there are no clear contraindications. Routine use of ACE inhibitors will lead to pro...

journal_title：European heart journal

authors： McKelvie R,McConachie D,Yusuf S

更新日期：1994-05-01 00:00:00

abstract：AIMS:This study investigated the relationship between right ventricular (RV) structure and function and survival in idiopathic pulmonary arterial hypertension (IPAH). METHODS AND RESULTS:In 64 patients, cardiac magnetic resonance, right heart catheterization, and the six-minute walk test (6MWT) were performed at basel...

journal_title：European heart journal

authors： van Wolferen SA,Marcus JT,Boonstra A,Marques KM,Bronzwaer JG,Spreeuwenberg MD,Postmus PE,Vonk-Noordegraaf A

更新日期：2007-05-01 00:00:00

abstract：:The magnitude and biological relevance in vivo of the beta-blocking properties, observed in vitro, of propafenone remains controversial. We studied the effects of propafenone on the heart rate response to graded stimulation of the right stellate ganglion in 13 anaesthetized, vagotomized cats. The decentralized ganglio...

journal_title：European heart journal

authors： Malfatto G,Pessano P,Zaza A,Schwartz PJ

更新日期：1993-09-01 00:00:00

abstract：:We have conducted a randomized, double-blind, placebo-controlled multicentre trial of oral isosorbide 5-mononitrate (ISMN) in 360 patients with suspected acute myocardial infarction. Patients were stratified prior to analysis according to the presence or absence of left ventricular failure on admission. ISMN caused a ...

journal_title：European heart journal

authors： Fitzgerald LJ,Bennett ED

更新日期：1990-02-01 00:00:00

abstract：:The study of 'atrial vulnerability' is often clinically indicated but it requires the use of invasive intracardiac stimulation. The purpose of the study was to assess the use of oesophageal pacing in the evaluation of atrial tachyarrhythmias (ATA). Fifty-five patients with documented ATA (group I) and 60 without (grou...

journal_title：European heart journal

authors： Brembilla-Perrot B

更新日期：1994-08-01 00:00:00

abstract：:Re-entry was demonstrated as a self-perpetuating mechanism as early as 1906. It may lead to single-cycle electrocardiographic phenomena as well as reciprocating tachycardias. Factors favouring re-entry are as follows. Unidirectional or temporary local block of conduction, a mechanism always involved in initiation of r...

journal_title：European heart journal

authors： Olsson SB

更新日期：1984-09-01 00:00:00

abstract：Aims:The aim of this study is to develop models to aid the decision to prolong dual antiplatelet therapy (DAPT) that requires balancing an individual patient's potential benefits and harms. Methods and results:Using population-based electronic health records (EHRs) (CALIBER, England, 2000-10), of patients evaluated 1 ...

journal_title：European heart journal

authors： Pasea L,Chung SC,Pujades-Rodriguez M,Moayyeri A,Denaxas S,Fox KAA,Wallentin L,Pocock SJ,Timmis A,Banerjee A,Patel R,Hemingway H

更新日期：2017-04-07 00:00:00

abstract：:Sixty patients (31 male, 29 female) were studied in a 4-week double-blind parallel dose-response study. Patients received amlodipine 1.25 mg (n = 12), 2.5 mg (n = 12), 5 mg (n = 12), 10 mg (n = 12) or placebo (n = 12) once a day. Anti-anginal efficacy was assessed by sequential treadmill testing 24 h post-dose, freque...

journal_title：European heart journal

authors： Cocco G,Alfiero R

更新日期：1991-02-01 00:00:00

abstract：:In a study of the concept of pacemaker dependence, 86 patients who had permanent ventricular demand (VVI) pacemakers implanted for more than six months and were in predominantly paced rhythm underwent repeated interruption of pacing both abruptly and after gradual reduction of paced rate. Non-invasive pace slowing was...

journal_title：European heart journal

authors： Crick JC,Rokas S,Sowton E

更新日期：1985-10-01 00:00:00

abstract：AIMS:Although embolic protection devices reduce complications during saphenous vein graft (SVG) stenting, adverse events still occur in approximately 10% of patients. IIb/IIIa antagonists have not been proven effective during SVG intervention. We hypothesized that adjunctive use of these agents might enhance the effica...

journal_title：European heart journal

authors： Jonas M,Stone GW,Mehran R,Hermiller J,Feldman R,Herrmann HC,Cox DA,Kuntz RE,Popma JJ,Rogers C,FilterWire EX Randomized Evalulation (FIRE) Investigators.

更新日期：2006-04-01 00:00:00

abstract：AIMS:Targeting interleukin-1 (IL-1) represents a novel therapeutic approach to atherosclerosis. CANTOS demonstrated the benefits of IL-1β neutralization in patients post-myocardial infarction with residual inflammatory risk. Yet, some mouse data have shown a prominent role of IL-1α rather than IL-1β in atherosclerosis,...

journal_title：European heart journal

authors： Vromman A,Ruvkun V,Shvartz E,Wojtkiewicz G,Santos Masson G,Tesmenitsky Y,Folco E,Gram H,Nahrendorf M,Swirski FK,Sukhova GK,Libby P

更新日期：2019-08-07 00:00:00

abstract：AIMS:The aim of the study was to compare the 10-year follow-up results of patients with or without restenosis following single-vessel percutaneous transluminal coronary angioplasty (PTCA). METHODS AND RESULTS:A total of 313 patients with successful PTCA (> or = 20% reduction in luminal diameter narrowing without acute...

journal_title：European heart journal

authors： Espinola-Klein C,Rupprecht HJ,Erbel R,Nafe B,Brennecke R,Meyer J

更新日期：1998-07-01 00:00:00

abstract：:The concept of coronary vascular reserve stems from the description of coronary autoregulation by Mosher in 1964. Schematically, the coronary blood flow at rest depends on the determinants of myocardial oxygen demand (heart rate, contractility and ventricular load). If maximal coronary vasodilation is produced, it res...

journal_title：European heart journal

authors： Nitenberg A,Antony I

更新日期：1995-08-01 00:00:00

abstract：:The purpose of this study was to evaluate the characteristics of mitral annular motion during diastole in 28 normal subjects, 40 patients with prior myocardial infarction (MI), and 23 patients with coronary artery disease but without prior MI. Mitral annular motion during diastole was obtained from the apex by M-mode ...

journal_title：European heart journal

authors： Ohte N,Narita H,Hashimoto T,Kobayashi K,Akita S,Fujinami T

更新日期：1995-07-01 00:00:00

abstract：:Advances in molecular genetics present new opportunities and challenges for cardiologists who manage patients and families with cardiomyopathies. The aims of this position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases are to review the general issues related to ge...

journal_title：European heart journal

authors： Charron P,Arad M,Arbustini E,Basso C,Bilinska Z,Elliott P,Helio T,Keren A,McKenna WJ,Monserrat L,Pankuweit S,Perrot A,Rapezzi C,Ristic A,Seggewiss H,van Langen I,Tavazzi L,European Society of Cardiology Working Group on

更新日期：2010-11-01 00:00:00

abstract：:The purpose of this study was to evaluate the accuracy of adenosine Tc-99m sestamibi single photon emission computed tomography (SPECT) in the detection of jeopardized myocardium early after acute myocardial infarction. Coronary arteriography and myocardial scintigraphy were performed in 50 consecutive patients with a...

journal_title：European heart journal

authors： Claeys MJ,Vrints CJ,Krug B,Bosmans JM,Blockx PP,Bossaert LL,Snoeck JP

更新日期：1995-09-01 00:00:00