Molecular determinants of myocardial hypertrophy and failure: alternative pathways for beneficial and maladaptive hypertrophy.

abstract：:Simultaneous two-channel Holter monitoring, with a direct recording system, and maximal exercise testing with a 12-lead precordial electrocardiographic mapping system were performed in 50 patients with chest pain (41 with documented coronary artery disease, 9 without). The exploring Holter leads were placed to corresp...

journal_title：European heart journal

authors： Egstrup K

更新日期：1988-04-01 00:00:00

abstract：:We evaluated the role of percutaneous transluminal coronary angioplasty (PTCA) in a series of orthotopic cardiac transplant recipients with severe epicardial coronary occlusive disease. Ten orthotopic cardiac transplant patients treated by PTCA up to March 1990 were reviewed. All had significant epicardial coronary ar...

journal_title：European heart journal

authors： Mullins PA,Shapiro LM,Aravot DA,Scott JP,Large SR,Wallwork J,Schofield PM

更新日期：1991-11-01 00:00:00

abstract：AIMS:Whereas endogenous carbon monoxide (CO) is cytoprotective at physiologic levels, excess CO concentrations are associated with cardiometabolic risk and may represent an important marker of progression from subclinical to clinical cardiovascular disease (CVD). METHODS AND RESULTS:In 1926 participants of the Framing...

journal_title：European heart journal

authors： Cheng S,Enserro D,Xanthakis V,Sullivan LM,Murabito JM,Benjamin EJ,Polak JF,O'Donnell CJ,Wolf PA,O'Connor GT,Keaney JF,Vasan RS

更新日期：2014-11-07 00:00:00

abstract：:Sequential alterations of left ventricular volumes and haemodynamics were studied in 29 patients between 4 days and 4 weeks after myocardial infarction. Left ventricular volume was determined by single photon emission computerized tomography (SPECT), infarct size by creatine kinase (CK) analysis, angiography and thall...

journal_title：European heart journal

authors： Gaudron P,Eilles C,Ertl G,Kochsiek K

更新日期：1990-04-01 00:00:00

abstract：AIMS:Inflammatory markers are established risk factors for atrial fibrillation (AF), but the role of autoimmune diseases is unknown. The aim of the study was to examine the association between coeliac disease (CD) and AF in a large cohort of patients with biopsy-verified CD. METHODS AND RESULTS:We identified 28,637 pa...

journal_title：European heart journal

authors： Emilsson L,Smith JG,West J,Melander O,Ludvigsson JF

更新日期：2011-10-01 00:00:00

abstract：:We describe a patient with a large intramyocardial hydatid cyst lying in the postero-lateral segment of the left ventricle near the atrioventricular groove level which ruptured into the pericardial sac, resulting in cardiac tamponade. Cross-sectional echocardiographic examination from a modified four-chamber apical vi...

journal_title：European heart journal

authors： De Martini M,Nador F,Binda A,Arpesani A,Odero A,Lotto A

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Anti-ischaemic therapy with nitrates and/or calcium channel blockers profoundly affects the results of pharmacological stress echocardiography with coronary vasodilators but the influence on catecholamine stress testing remains unsettled. AIMS:The present study aimed to assess the effects of non-beta-blocke...

journal_title：European heart journal

authors： Dodi C,Pingitore A,Sicari R,Bruno G,Cordovil A,Picano E

更新日期：1997-02-01 00:00:00

abstract：:A major consequence of chronic cardiac dysfunction is chronic overload of contractile myocardium. Various aetiologies, in reaction to this, may induce compensatory mechanisms consisting of excentric (dilatation) and concentric hypertrophy. Chronic left ventricular dysfunction is caused most frequently by myocardial in...

journal_title：European heart journal

authors： Ertl G,Gaudron P,Neubauer S,Bauer B,Horn M,Hu K,Tian R

更新日期：1993-07-01 00:00:00

abstract：AIMS:The study set out to assess the relative contributions of donor heart rate, respiration and recipient atrial contraction on the mean of pulsed wave transmitral Doppler flow indices in orthotopic heart transplant recipients. This would provide information on the theoretical usefulness of pacemaker synchronization o...

journal_title：European heart journal

authors： Mannaerts H,Balk A,Roelandt J

更新日期：1997-10-01 00:00:00

abstract：:Stress echocardiography is an established method for the diagnosis and prognostic stratification of coronary artery disease. In the last few years, the tremendous technological and conceptual versatility of this technique has been increasingly applied in challenging diagnostic fields. Today, in the echocardiography la...

journal_title：European heart journal

authors： Picano E,Pellikka PA

更新日期：2014-04-01 00:00:00

abstract：AIMS:Real-time MRI creates images with superb tissue contrast that may enable radiation-free catheterization. Simple procedures are the first step towards novel interventional procedures. We aim to perform comprehensive transfemoral diagnostic right heart catheterization in an unselected cohort of patients entirely usi...

journal_title：European heart journal

authors： Ratnayaka K,Faranesh AZ,Hansen MS,Stine AM,Halabi M,Barbash IM,Schenke WH,Wright VJ,Grant LP,Kellman P,Kocaturk O,Lederman RJ

更新日期：2013-02-01 00:00:00

abstract：AIMS:We analysed the contemporary incidence, outcomes, and predictors of heart failure (HF) and/or left ventricular systolic dysfunction (LVSD) before discharge in patients with acute myocardial infarction (MI). The baseline presence of HF or LVSD, or its development during hospitalisation, increases short- and long-te...

journal_title：European heart journal

authors： Velazquez EJ,Francis GS,Armstrong PW,Aylward PE,Diaz R,O'Connor CM,White HD,Henis M,Rittenhouse LM,Kilaru R,van Gilst W,Ertl G,Maggioni AP,Spac J,Weaver WD,Rouleau JL,McMurray JJ,Pfeffer MA,Califf RM,VALIANT registr

更新日期：2004-11-01 00:00:00

abstract：AIMS:This ancillary analysis of the GISSI-HF database aims at assessing the effect of rosuvastatin on the occurrence of atrial fibrillation (AF) in patients with chronic heart failure (HF) who were not in AF at study entry. METHODS AND RESULTS:GISSI-HF was a double-blind, placebo-controlled trial testing n-3 PUFA and ...

journal_title：European heart journal

authors： Maggioni AP,Fabbri G,Lucci D,Marchioli R,Franzosi MG,Latini R,Nicolosi GL,Porcu M,Cosmi F,Stefanelli S,Tognoni G,Tavazzi L,GISSI-HF Investigators.

更新日期：2009-10-01 00:00:00

abstract：AIMS:Ivabradine, a new I(f) inhibitor which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent. Ivabradine has shown anti-ischaemic and anti-anginal activity in a placebo-controlled trial. The objective of this study was to compare the anti-anginal and anti-ischaemic...

journal_title：European heart journal

authors： Tardif JC,Ford I,Tendera M,Bourassa MG,Fox K,INITIATIVE Investigators.

更新日期：2005-12-01 00:00:00

abstract：:The fundamental abnormality in syndrome X (angina pectoris, ischaemia-like stress ECG despite angiographically normal coronary arteries) might be patchily distributed increased tone in pre-arteriolar coronary vessels with compensatory release of adenosine. The aim of this study was to confirm this hypothesis and to ex...

journal_title：European heart journal

authors： Meeder JG,Blanksma PK,Crijns HJ,Anthonio RL,Pruim J,Brouwer J,de Jong RM,van der Wall EE,Vaalburg W,Lie KI

更新日期：1995-11-01 00:00:00

abstract：:Hemodynamic variables were measured in 34 patients with isolated systolic hypertension before and after acute administration of propranolol. The patients were separated into two groups, those younger than and those older than 45 years of age, respectively. After drug administration, systolic pressure decreased signifi...

journal_title：European heart journal

authors： Levenson J,Simon A,Maarek B,Totomoukouo J,Gitelman R,Bouthier J,Safar M

更新日期：1983-11-01 00:00:00

abstract：AIMS:Quantitative analysis of rest-stress myocardial perfusion magnetic resonance imaging (MRI) can provide assessments of regional myocardial perfusion reserve (MPR). The purpose of this study was to compare regional MPR determined by myocardial perfusion MRI with coronary flow reserve (CFR) by intracoronary Doppler f...

journal_title：European heart journal

authors： Kurita T,Sakuma H,Onishi K,Ishida M,Kitagawa K,Yamanaka T,Tanigawa T,Kitamura T,Takeda K,Ito M

更新日期：2009-02-01 00:00:00

abstract：:In a 2-D model of anisotropy, created by freezing the intramural and endocardial layers of a Langendorf perfused rabbit heart, sustained ventricular tachycardia (VT) with a cycle length of 130 ms and an excitable gap of 30 ms could be initiated by rapid pacing. High resolution mapping (256 points) of the thin survivin...

journal_title：European heart journal

authors： Allessie MA,Schalij MJ,Kirchhof CJ,Boersma L,Huybers M,Hollen J

更新日期：1989-09-01 00:00:00

abstract：:We investigated whether left ventricular hypertrophy in elite cyclists is associated with functional changes or abnormal energy metabolism. Left ventricular hypertrophy is a powerful risk factor for sudden cardiac death with different prognostic significance among the various geometric forms. Cyclists may have a combi...

journal_title：European heart journal

authors： Pluim BM,Chin JC,De Roos A,Doornbos J,Siebelink HM,Van der Laarse A,Vliegen HW,Lamerichs RM,Bruschke AV,Van der Wall EE

更新日期：1996-08-01 00:00:00

abstract：:The antibody prevalence data indicate that C. pneumoniae infections are common worldwide and more frequently occur in middle-aged and elderly males than in females. C. pneumoniae infections are first acquired in childhood in heavily populated areas, whereas in northern countries, first infections are generally at teen...

journal_title：European heart journal

authors： Leinonen M

更新日期：1993-12-01 00:00:00

abstract：Aims:Pulmonary hypertension (PH) and pulmonary vascular disease (PVD) are common and associated with adverse outcomes in heart failure with preserved ejection fraction (HFpEF). Little is known about the impact of PVD on the pathophysiology of exercise intolerance. Methods and results:Heart failure with preserved eject...

journal_title：European heart journal

authors： Gorter TM,Obokata M,Reddy YNV,Melenovsky V,Borlaug BA

更新日期：2018-08-07 00:00:00

abstract：AIMS:The risk of gastrointestinal (GI) bleeding limits the use of antiplatelet and anticoagulant drugs. Risk factors for GI bleeding in post- myocardial infarction (MI) patients have not been well defined. We sought to identify risk factors for GI bleeding in patients following MI. METHODS AND RESULTS:The VALsartan In...

journal_title：European heart journal

authors： Moukarbel GV,Signorovitch JE,Pfeffer MA,McMurray JJ,White HD,Maggioni AP,Velazquez EJ,Califf RM,Scheiman JM,Solomon SD

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:While prior work has suggested that a high-grade atrioventricular block (HAVB) in the setting of an acute coronary syndrome (ACS) is associated with in-hospital death, limited information is available on the incidence of, and death associated with, HAVB in ACS patients receiving contemporary management. MET...

journal_title：European heart journal

authors： Singh SM,FitzGerald G,Yan AT,Brieger D,Fox KA,López-Sendón J,Yan RT,Eagle KA,Steg PG,Budaj A,Goodman SG

更新日期：2015-04-21 00:00:00

abstract：:Recent innovations have the potential to improve rhythm control therapy in patients with atrial fibrillation (AF). Controlled trials provide new evidence on the effectiveness and safety of rhythm control therapy, particularly in patients with AF and heart failure. This review summarizes evidence supporting the use of ...

journal_title：European heart journal

authors： Willems S,Meyer C,de Bono J,Brandes A,Eckardt L,Elvan A,van Gelder I,Goette A,Gulizia M,Haegeli L,Heidbuchel H,Haeusler KG,Kautzner J,Mont L,Ng GA,Szumowski L,Themistoclakis S,Wegscheider K,Kirchhof P

更新日期：2019-12-07 00:00:00

abstract：:In this study, two patterns of regional contract on of the left ventricle have been studied: endocardial motion and wall thickening, in order to check which of these was the most affected after myocardial infarction. The clinical relevance of this comparison was to assess which parameter of the regional contraction ab...

journal_title：European heart journal

authors： Germain P,Roul G,Constantinesco A,Coulbois PM,Baruthio J,Mossard JM,Bareiss P,Sacrez A

更新日期：1996-09-01 00:00:00

abstract：:Measurement of the pre-ejection period (PEP) can give valuable information on myocardial function in rats. Depressed cardiac function is accompanied by prolongation of PEP, which shortens when cardiac function improves. Left ventricular ejection time (LVET) may be shortened with ageing in spontaneously hypertensive ra...

journal_title：European heart journal

authors： Schoemaker RG,Smits JF

更新日期：1990-12-01 00:00:00

abstract：:In atrial flutter, chemical conversion with class I drugs is often unsuccessful, whereas class III drugs seem more promising. The different electrophysiological effects of these drugs may explain this discrepancy. To date, only experimental data show the differential effects of these drugs on conversion rate and atria...

journal_title：European heart journal

authors： Crijns HJ,Van Gelder IC,Kingma JH,Dunselman PH,Gosselink AT,Lie KI

更新日期：1994-10-01 00:00:00

abstract：:The efficacy of sustained-release diltiazem (diltiazem-SR) 120 mg b.i.d. was compared with metoprolol 100 mg b.i.d. in 12 patients with stable angina. Following a 1-week placebo period, patients received diltiazem-SR or metoprolol in two 3-week treatment periods, in a randomized double-blind crossover design. Total ex...

journal_title：European heart journal

authors： Posma JL,van Dijk RB,Lie KI

更新日期：1989-10-01 00:00:00

abstract：AIMS:Subjects with lipoprotein(a) [Lp(a)] elevation have increased arterial wall inflammation and cardiovascular risk. In patients at increased cardiovascular risk, arterial wall inflammation is reduced following lipid-lowering therapy by statin treatment or lipoprotein apheresis. However, it is unknown whether lipid-l...

journal_title：European heart journal

authors： Stiekema LCA,Stroes ESG,Verweij SL,Kassahun H,Chen L,Wasserman SM,Sabatine MS,Mani V,Fayad ZA

更新日期：2019-09-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of nadolol in modifying the standard deviation of RR intervals (SDRR) and the coefficient of variance (CV) in 47 patients characterized by symptomatic, frequent (> 30 h-1) and reproducible premature ventricular contractions (PVCs). Sixteen patients had suffered a previo...

journal_title：European heart journal

authors： Pitzalis MV,Mastropasqua F,Massari F,Totaro P,Passantino A,Rizzon P

更新日期：1995-02-01 00:00:00