Cardiac dysfunction and development of heart failure.

abstract：:The cytokine hypothesis presently suggests that an excessive production of pro-inflammatory cytokines, such as tumour necrosis factor alpha (TNF) and interleukin 6 (IL6), contributes to the pathogenesis of heart failure. The concept, successfully proved in genetically modified animal models, failed to translate to hum...

journal_title：European heart journal

authors： Lecour S,James RW

更新日期：2011-03-01 00:00:00

abstract：AIMS:Resuscitated cardiac arrest (CA), leading to harmful cardiovascular dysfunction and multiple organ failure, includes a whole-body hypoxia-reoxygenation phenomenon. Opening of the mitochondrial permeability transition pore (mPTP) appears to be a pivotal event in ischaemia-reperfusion injury. We hypothesized that ph...

journal_title：European heart journal

authors： Cour M,Loufouat J,Paillard M,Augeul L,Goudable J,Ovize M,Argaud L

更新日期：2011-01-01 00:00:00

abstract：Aims:Pulmonary hypertension (PH) and pulmonary vascular disease (PVD) are common and associated with adverse outcomes in heart failure with preserved ejection fraction (HFpEF). Little is known about the impact of PVD on the pathophysiology of exercise intolerance. Methods and results:Heart failure with preserved eject...

journal_title：European heart journal

authors： Gorter TM,Obokata M,Reddy YNV,Melenovsky V,Borlaug BA

更新日期：2018-08-07 00:00:00

abstract：AIMS:The prognostic role of time-to-treatment in primary angioplasty is still a matter of debate. The aim of our study was to evaluate the relationship between time-to-treatment and myocardial perfusion in patients with ST-segment-elevation myocardial infarction (STEMI) treated by primary angioplasty. METHODS AND RESU...

journal_title：European heart journal

authors： De Luca G,van 't Hof AW,de Boer MJ,Ottervanger JP,Hoorntje JC,Gosselink AT,Dambrink JH,Zijlstra F,Suryapranata H

更新日期：2004-06-01 00:00:00

abstract：AIMS:Although a recent expert consensus statement has recommended periprocedural uninterrupted (UI) non-vitamin K antagonist oral anticoagulants (NOACs) during catheter ablation of atrial fibrillation (AF) as a Class I indication, there have been no clear randomized trials. We investigated the safety and efficacy of UI...

journal_title：European heart journal

authors： Yu HT,Shim J,Park J,Kim TH,Uhm JS,Kim JY,Joung B,Lee MH,Kim YH,Pak HN

更新日期：2019-05-14 00:00:00

abstract：AIMS:Increased cardiovascular morbidity is manifested a long time after the repair of aortic coarctation (CoA). By way of impaired flow-mediated vasodilation (FMD) and increased intima media thickness (IMT), surrogate parameters of atherosclerosis, cardiovascular risk factors (RFs) can be correlated with early vascular...

journal_title：European heart journal

authors： Meyer AA,Joharchi MS,Kundt G,Schuff-Werner P,Steinhoff G,Kienast W

更新日期：2005-03-01 00:00:00

abstract：:The role of ventricular rate-adaptive pacing (VVIR) in the elderly was investigated in 12 patients with a mean age of 85 +/- 2 years (range 75-95 years) with implanted activity-initiated VVIR pacemakers. Although four patients had significant extracardiac diseases, all were capable of independent walking and self care...

journal_title：European heart journal

authors： Lau CP,Wong CK,Tai YT,Fong PC,Li JP,Chung FL

更新日期：1992-07-01 00:00:00

abstract：AIM:Little is known about the prognostic significance of silent versus symptomatic coronary artery disease (CAD) in diabetic patients. We therefore assessed the incidence of scintigraphic evidence of CAD in diabetic patients without known CAD and the impact of symptoms and scintigraphic findings on prognosis. METHODS ...

journal_title：European heart journal

authors： Zellweger MJ,Hachamovitch R,Kang X,Hayes SW,Friedman JD,Germano G,Pfisterer ME,Berman DS

更新日期：2004-04-01 00:00:00

abstract：:Myocardial relaxation is an energy-dependent process. Indeed, adenosine triphosphate (ATP) is required to pump free myoplasmic calcium back into the sarcoplasmic reticulum. It is also necessary to extrude the calcium ions which enter the cell during the plateau phase of the action potential. The calcium-sodium exchang...

journal_title：European heart journal

authors： Pouleur H

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:In patients with postinfarction sustained ventricular tachycardia showing one or more antiarrhythmic drug failures, the question is how long to proceed with new drug trials before deciding to perform map-guided arrhythmia surgery. Although the techniques of this surgery developed rapidly in the early 1980s, ...

journal_title：European heart journal

authors： van Hemel NM,Kingma JH,Defauw JJ,Hoogteijling-van Dusseldorp E,Kelder JC,Beukema WP,Vermeulen FE

更新日期：1996-04-01 00:00:00

abstract：AIMS:Experimental and clinical studies indicate that tea exerts protection against cardiovascular diseases. However, a question of much debate is whether addition of milk modifies the biological activities of tea. We studied the vascular effects of tea, with or without milk, in humans and elucidated the impact of indiv...

journal_title：European heart journal

authors： Lorenz M,Jochmann N,von Krosigk A,Martus P,Baumann G,Stangl K,Stangl V

更新日期：2007-01-01 00:00:00

abstract：:This state-of-the-art review aims to provide an up-to-date look at breakthrough omic technologies that are helping to unravel heart failure (HF) disease mechanisms and heterogeneity. Genomics, transcriptomics, proteomics, and metabolomics in HF are reviewed in depth. In addition, there is a thorough, expert discussion...

journal_title：European heart journal

authors： Bayes-Genis A,Liu PP,Lanfear DE,de Boer RA,González A,Thum T,Emdin M,Januzzi JL

更新日期：2020-09-21 00:00:00

abstract：AIMS:In mechanical heart valve recipients, low-dose international normalized ratio (INR) self-management of oral anticoagulants can reduce the risk of developing thrombo-embolic events and improve long-term survival compared with INR control by a general practitioner. Here, we present data on the safety of low-dose INR...

journal_title：European heart journal

authors： Koertke H,Zittermann A,Tenderich G,Wagner O,El-Arousy M,Krian A,Ennker J,Taborski U,Klövekorn WP,Moosdorf R,Saggau W,Koerfer R

更新日期：2007-10-01 00:00:00

abstract：:The aim of our study was to examine if echocardiography can reproducibly be used in a multicentre study to select high risk patients with reduced left ventricular function early after an acute myocardial infarction (MI). In the TRAndolapril Cardiac Evaluation Study (TRACE) patients with reduced left ventricular systol...

journal_title：European heart journal

authors： Køber L,Torp-Pedersen C,Carlsen J,Videbaek R,Egeblad H

更新日期：1994-12-01 00:00:00

abstract：:Despite therapeutic improvements, cardiogenic shock (CS) remains the most common cause of death in patients with acute myocardial infarction (AMI). In addition to percutaneous coronary intervention, inotropes, fluids, adjunctive medication, intra-aortic balloon counterpulsation, and also assist devices are widely used...

journal_title：European heart journal

authors： Thiele H,Allam B,Chatellier G,Schuler G,Lafont A

更新日期：2010-08-01 00:00:00

abstract：:Unstable angina is a high-risk phase of coronary heart disease defined by clinical symptoms. Electrocardiographic findings are heterogeneous and creatine kinase is only rarely elevated. However, troponin T and troponin I are found in about 30-40% of patients with angina at rest disclosing minor myocardial cell injury....

journal_title：European heart journal

authors： Hamm CW

更新日期：1998-11-01 00:00:00

abstract：:Between 1968 and 1984, 78 patients (mean age 43, range 14 to 65 years) underwent combined aortic, mitral and tricuspid surgery (22 triple valve replacements, 56 aortic valve replacements with tricuspid conservative surgery and mitral valve replacement (N = 48), or commissuroplasty (N = 8). Pre-operative consequences o...

journal_title：European heart journal

authors： Michel PL,Houdart E,Ghanem G,Badaoui G,Hage A,Acar J

更新日期：1987-05-01 00:00:00

abstract：AIMS:To investigate the effects of secretory phospholipase A2 (sPLA(2)) inhibition on plasma lipoproteins. Secretory phospholipase A2 isoenzymes promote atherosclerosis by mechanisms that include lipoprotein modification, retention, and oxidation. METHODS AND RESULTS:Phospholipase Levels And Serological Markers of Ath...

journal_title：European heart journal

authors： Rosenson RS,Elliott M,Stasiv Y,Hislop C,PLASMA II Investigators.

更新日期：2011-04-01 00:00:00

abstract：:A patient with a three-year history of recurrent pulmonary embolism is presented. Thromboembolic pulmonary hypertension was proven in the final stage of disease in the presence of repeated episodes of systemic embolic events. Paradoxical embolism was assumed to be present on the basis of blood-gas analysis and contras...

journal_title：European heart journal

authors： Lang I,Steurer G,Weissel M,Burghuber OC

更新日期：1988-06-01 00:00:00

abstract：:Forty patients with prosthetic valve endocarditis (PVE) presenting during a 12-year period at a single hospital were studied. Twenty-six were male and 14 female and ages ranged from 19 to 67 years. During the first six post-operative months, most episodes were caused by staphylococci (38%) and Gram negative bacilli (2...

journal_title：European heart journal

authors： Gayet JL,Etienne J,Malquarti V,Gruer LD,Didier B,Chuzel M,Champsaur G,Chassignolle J,Fleurette J,Delaye J

更新日期：1984-10-01 00:00:00

abstract：:Three siblings with familial Wolff-Parkinson-White syndrome and two instances of sudden death are described. In all of them, multiple accessory pathways with a very short anterograde refractory period and rapid ventricular responses during atrial fibrillation had been documented, thus surgical ablation of the bypass t...

journal_title：European heart journal

authors： Patruno N,Coltorti F,Pulignano G,Urbani P,Critelli G

更新日期：1990-12-01 00:00:00

abstract：AIM:To compare patients treated for heart failure in relation to the management in general practices versus hospital admission. METHODS AND RESULTS:Twelve randomly selected general practices (GP) were screened for patients receiving ACE-inhibitor, digoxin, or loop diuretic treatment. The first 500 volunteers of 959 po...

journal_title：European heart journal

authors： Nielsen OW,McDonagh T,Cowburn P,Blue L,Robb SD,Dargie H

更新日期：2004-10-01 00:00:00

abstract：AIMS:The aim of this study was to assess the risk of intra-aortic balloon counterpulsation and to identify clinical and procedural variables that would predict complications. METHODS AND RESULTS:We analysed 381 consecutive patients who were treated between 1977 and 1995 at our catheterization laboratory and/or medical...

journal_title：European heart journal

authors： Scholz KH,Ragab S,von zur Mühlen F,Schröder T,Werner GS,Mindel L,Kreuzer H

更新日期：1998-03-01 00:00:00

abstract：:The aim of the present investigation was to evaluate the type and the incidence of cardiac arrhythmias and ischaemic events in patients suffering from testicular cancer and submitted to combination chemotherapy with cisplatin, bleomycin and vinblastine (PVB) or etoposide (PEB). Forty-seven patients took part in the st...

journal_title：European heart journal

authors： Villani F,Misrachi D,Galimberti M

更新日期：1994-11-01 00:00:00

abstract：AIM:Short-term psychological stress is associated with an immediate physiological response and may be associated with a transiently higher risk of cardiovascular events. The aim of this study was to determine whether brief episodes of anger trigger the onset of acute myocardial infarction (MI), acute coronary syndromes...

journal_title：European heart journal

authors： Mostofsky E,Penner EA,Mittleman MA

更新日期：2014-06-01 00:00:00

abstract：AIM:To evaluate the effect of alirocumab on frequency of standard apheresis treatments [weekly or every 2 weeks (Q2W)] in heterozygous familial hypercholesterolaemia (HeFH). METHODS AND RESULTS:ODYSSEY ESCAPE (NCT02326220) was a double-blind study in 62 HeFH patients undergoing regular weekly or Q2W lipoprotein aphere...

journal_title：European heart journal

authors： Moriarty PM,Parhofer KG,Babirak SP,Cornier MA,Duell PB,Hohenstein B,Leebmann J,Ramlow W,Schettler V,Simha V,Steinhagen-Thiessen E,Thompson PD,Vogt A,von Stritzky B,Du Y,Manvelian G

更新日期：2016-12-21 00:00:00

abstract：:The first marathon run as an athletic event took place in the context of the Olympic Games in 1896 in Athens, Greece. Today, participation in a 'marathon run' has become a global phenomenon attracting young professional athletes as well as millions of mainly middle-aged amateur athletes worldwide each year. One of the...

journal_title：European heart journal

authors： Predel HG

更新日期：2014-11-21 00:00:00

abstract：:Myocardial bridging of the left anterior descending coronary artery producing complete systolic occlusion was demonstrated in a patient with hypertrophic cardiomyopathy, who had localized myocardial hypertrophy in the lateral left ventricular wall outside the territory of that artery. Although a cause and effect relat...

journal_title：European heart journal

authors： Doi YL,Yamada M,Hamashige N,Yonezawa Y,Odawara H,Ozawa T

更新日期：1987-07-01 00:00:00

abstract：AIMS:Left ventricular (LV) hypertrophy and abnormal non-invasive measures of LV diastolic function are common in patients with severe aortic stenosis (AS) but their prognostic importance is uncertain. This study aimed to determine whether tissue Doppler measures of LV systolic and/or diastolic function or echocardiogra...

journal_title：European heart journal

authors： Stewart RA,Kerr AJ,Whalley GA,Legget ME,Zeng I,Williams MJ,Lainchbury J,Hamer A,Doughty R,Richards MA,White HD,New Zealand Heart Valve Study Investigators.

更新日期：2010-09-01 00:00:00

abstract：:A 45-year-old patient with the Wolff-Parkinson-White syndrome suffering from recurrent intractable reciprocating atrioventricular tachycardia (RAVT) is reported. He used amiodarone, sotalol, quinidine, propafenone and flecainide unsuccessfully. An electrophysiological study (EPS) performed with four catheters localize...

journal_title：European heart journal

authors： Delise P,Bonso A,Raviele A,Cazzin R,Di Pede F,Piccolo E

更新日期：1991-12-01 00:00:00