Efficacy of ivabradine, a new selective I(f) inhibitor, compared with atenolol in patients with chronic stable angina.

abstract：:A previously described nitroglycerin-induced heparin resistance could not be verified by in-vitro experiments or in a randomized, double-blind, crossover trial in healthy volunteers. A clinically relevant attenuation of the anticoagulant effect of a heparin bolus (40 U.kg-1) by a concomitant infusion of nitroglycerin ...

journal_title：European heart journal

authors： Schoenenberger RA,Ménat L,Weiss P,Marbet GA,Ritz R

更新日期：1992-03-01 00:00:00

abstract：AIMS:Long-term randomized comparisons of percutaneous coronary intervention (PCI) to coronary artery bypass grafting (CABG) in left main coronary (LM) disease and/or three-vessel disease (3VD) patients have been limited. This analysis compares 3-year outcomes in LM and/or 3VD patients treated with CABG or PCI with TAXU...

journal_title：European heart journal

authors： Kappetein AP,Feldman TE,Mack MJ,Morice MC,Holmes DR,Ståhle E,Dawkins KD,Mohr FW,Serruys PW,Colombo A

更新日期：2011-09-01 00:00:00

abstract：:Unstable angina is a high-risk phase of coronary heart disease defined by clinical symptoms. Electrocardiographic findings are heterogeneous and creatine kinase is only rarely elevated. However, troponin T and troponin I are found in about 30-40% of patients with angina at rest disclosing minor myocardial cell injury....

journal_title：European heart journal

authors： Hamm CW

更新日期：1998-11-01 00:00:00

abstract：AIMS:N-terminal pro-brain natriuretic peptide (NT-proBNP) levels predict outcomes in ST-elevation myocardial infarction patients treated with fibrinolysis or primary percutaneous coronary intervention (PCI). However, its role in facilitated PCI has not yet been assessed; it may be a tool to evaluate the lower event rat...

journal_title：European heart journal

authors： Sinnaeve PR,Ezekowitz JA,Bogaerts K,Droogne W,Jarai R,Huber K,Granger CB,Desmet WJ,Armstrong PW,Van de Werf FJ,ASSENT-4 PCI Investigators.

更新日期：2009-09-01 00:00:00

abstract：AIMS:Non-vitamin K antagonist oral anticoagulants (NOACs) require dose reductions according to patient or clinical factors for patients with atrial fibrillation (AF). In this meta-analysis, we aimed to assess outcomes with reduced-dose NOACs when given as pre-specified in pivotal trials. METHODS AND RESULTS:Aggregated...

journal_title：European heart journal

authors： Wang KL,Lopes RD,Patel MR,Büller HR,Tan DS,Chiang CE,Giugliano RP

更新日期：2019-05-14 00:00:00

abstract：AIMS:Resuscitated cardiac arrest (CA), leading to harmful cardiovascular dysfunction and multiple organ failure, includes a whole-body hypoxia-reoxygenation phenomenon. Opening of the mitochondrial permeability transition pore (mPTP) appears to be a pivotal event in ischaemia-reperfusion injury. We hypothesized that ph...

journal_title：European heart journal

authors： Cour M,Loufouat J,Paillard M,Augeul L,Goudable J,Ovize M,Argaud L

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:We investigated whether apolipoprotein A1 (ApoA1) could better identify patients with severe vessel damage than HDL-cholesterol in a population with recent acute myocardial infarction (AMI). METHODS:One hundred and forty-one male patients (mean age: 54.3 +/- 7.3 years) who had undergone coronary angiograp...

journal_title：European heart journal

authors： Garfagnini A,Devoto G,Rosselli P,Boggiano P,Venturini M

更新日期：1995-04-01 00:00:00

abstract：AIMS:Combined quantitative coronary angiography and intracoronary Doppler flow velocity measurements were performed to study the underlying haemodynamic mechanisms leading to myocardial ischaemia in patients with myocardial bridging in the absence of coronary artery disease. METHODS AND RESULTS:In 42 symptomatic patie...

journal_title：European heart journal

authors： Schwarz ER,Klues HG,vom Dahl J,Klein I,Krebs W,Hanrath P

更新日期：1997-03-01 00:00:00

abstract：AIMS:This study evaluated the predictive value of NT-proBNP for patients with diabetes mellitus and compared the prognostic aptitude of this neurohumoral marker to traditional markers of cardiovascular events. METHODS AND RESULTS:A prospective observational study was conducted in 631 diabetic patients. The composite e...

journal_title：European heart journal

authors： Huelsmann M,Neuhold S,Strunk G,Moertl D,Berger R,Prager R,Abrahamian H,Riedl M,Pacher R,Luger A,Clodi M

更新日期：2008-09-01 00:00:00

abstract：Aims:Vascular ageing is characterized by arterial stiffening, dilation, and arterial wall thickening. We investigated the extent to which these changes are related and their heritability during 5 year follow-up in the Twins UK cohort. Methods and results:Carotid-femoral pulse wave velocity (PWVcf), carotid diameter, c...

journal_title：European heart journal

authors： Cecelja M,Jiang B,Keehn L,Hussain T,Silva Vieira M,Phinikaridou A,Greil G,Spector TD,Chowienczyk P

更新日期：2018-06-21 00:00:00

abstract：:In a pilot study, a computerized precordial mapping system monitored ischaemia on-line in 50 patients (40 with acute myocardial infarction and 10 with unstable angina, class IV (Canadian Cardiovascular Society). All had ST-segment depression or elevation greater than or equal to 0.2 mV in one or more precordial leads ...

journal_title：European heart journal

authors： von Essen R,Hinsen R,Louis R,Merx W,Silny J,Rau G,Effert S

更新日期：1984-03-01 00:00:00

abstract：:We performed echocardiographic evaluation of 20 male veteran endurance runners (mean age 56 +/- 7 years) and compared them with a group of age-matched controls. All the runners had run at least 25 miles per week for more than 25 years. Although only four athletes showed voltage ECG evidence of left ventricular hypertr...

journal_title：European heart journal

authors： Northcote RJ,McKillop G,Todd IC,Canning GP

更新日期：1990-01-01 00:00:00

abstract：:This report of an ESC Study Group reviews current knowledge on myocardial hibernation and relevant imaging techniques, and provides an algorithm for investigation and management when a patient presents with ischaemic left ventricular dysfunction. It covers the definitions of myocardial viability, stunning and hibernat...

journal_title：European heart journal

authors： Underwood SR,Bax JJ,vom Dahl J,Henein MY,Knuuti J,van Rossum AC,Schwarz ER,Vanoverschelde JL,van der Wall EE,Wijns W,Study Group of the European Society of Cardiology.

更新日期：2004-05-01 00:00:00

abstract：AIMS:The aim of the study was to evaluate the long-term results of allograft and prosthetic valve replacement in the treatment of infective aortic valve endocarditis with periannular abscess. METHODS:Between March 1988 and March 1996, 65 patients underwent surgery for active aortic valve endocarditis and paravalvular ...

journal_title：European heart journal

authors： Knosalla C,Weng Y,Yankah AC,Siniawski H,Hofmeister J,Hammerschmidt R,Loebe M,Hetzer R

更新日期：2000-03-01 00:00:00

abstract：AIMS:The association of body weight and weight change with mortality and cardiovascular (CV) outcome in patients with diabetes mellitus (DM) is not clearly established. We assessed the relationship between weight, weight change, and outcomes in patients with established CV risk factors and type 2 DM or pre-diabetes. M...

journal_title：European heart journal

authors： Doehner W,Gerstein HC,Ried J,Jung H,Asbrand C,Hess S,Anker SD

更新日期：2020-07-21 00:00:00

abstract：AIMS:This study compares the functional outcome and cardiorespiratory response to exercise, in patients who have undergone arterial switch for transposition of the great arteries, with normal controls and patients who have undergone atrial switch operation. METHODS AND RESULTS:Fifteen patients who had undergone arteri...

journal_title：European heart journal

authors： Reybrouck T,Eyskens B,Mertens L,Defoor J,Daenen W,Gewillig M

更新日期：2001-06-01 00:00:00

abstract：:To assess the clinical significance of monitoring during physical training in post-myocardial infarction (MI) patients with asymptomatic exercise-induced ischaemia, we studied 232 patients who were survivors of first recent acute MI and consecutively admitted to the same CCU, who underwent an exercise test (ET) and co...

journal_title：European heart journal

authors： Opasich C,Riccardi G,Assandri J,Calsamiglia G,Forni R,La Rovere M,Cobelli F,De Servi S,Specchia G

更新日期：1988-12-01 00:00:00

abstract：AIMS:The importance of heart rate in the pathophysiology of heart failure with reduced LVEF has recently attracted attention. In particular, the findings of the Systolic Heart failure treatment with the I(f) inhibitor ivabradine Trial (SHIFT) have put special emphasis on heart rate reduction with ivabradine for improve...

journal_title：European heart journal

authors： Castagno D,Petrie MC,Claggett B,McMurray J

更新日期：2012-05-01 00:00:00

abstract：:Organic nitrates exert their effect by direct inhibition of vascular tone, resulting in decreased myocardial oxygen demand and improved oxygen supply. Less well known is the effect of nitrates on blood rheology. To evaluate the haemodiluting effect of intravenous nitroglycerin we studied 70 consecutive patients admitt...

journal_title：European heart journal

authors： Arend SM,Bax JJ,Hermans J,van der Wall EE,Sedney MI

更新日期：1994-01-01 00:00:00

abstract：UNLABELLED:Peripheral vessels provide a useful in vivo haemodynamic model allowing evaluation of local intravascular fluid dynamics. Velocity measurements using a 0.018 inch Doppler-tipped angioplasty guidewire, quantitative angiography and laboratory data were gathered from 45 patients with a total of 48 percutaneous ...

journal_title：European heart journal

authors： Wellnhofer E,Biamino G,Sauer HU,Trebeljahr A,Stalke J,Ragg C,Oswald H,Gotze S,Fleck E,Felix R

更新日期：1995-10-01 00:00:00

abstract：AIMS:The Occluded Artery Trial (OAT) (n = 2201) showed no benefit for routine percutaneous intervention (PCI) (n = 1101) over medical therapy (MED) (n = 1100) on the combined endpoint of death, myocardial infarction (MI), and class IV heart failure (congestive heart failure) in stable post-MI patients with late occlude...

journal_title：European heart journal

authors： Menon V,Pearte CA,Buller CE,Steg PG,Forman SA,White HD,Marino PN,Katritsis DG,Caramori P,Lasevitch R,Loboz-Grudzien K,Zurakowski A,Lamas GA,Hochman JS

更新日期：2009-01-01 00:00:00

abstract：:Ten patients with chronic intermittent claudication were included in a double-blind, randomized cross-over study of placebo, propranolol 80 mg b.i.d. and metoprolol 100 mg b.i.d., each given for two months. At the end of each treatment period, the patients were tested on a treadmill and the time to first claudication ...

journal_title：European heart journal

authors： Bogaert MG,Clement DL

更新日期：1983-03-01 00:00:00

abstract：:Three different bradycardic agents, alinidine, AQ-A39 and UL-FS49 increase the intrinsic cycle length of the isolated SA node preparation of the rabbit. This increase is mainly caused by a decrease in rate of diastolic depolarization. One of these agents, alinidine, was used to study the underlying ionic mechanism of ...

journal_title：European heart journal

authors： van Ginneken AC,Bouman LN,Jongsma HJ,Duivenvoorden JJ,Opthof T,Giles WR

更新日期：1987-12-01 00:00:00

abstract：:From 1978 to 1980, 260 healthy subjects, 40-79 years of age, underwent 24 h ambulatory electrocardiography in order to determine the prevalence and complexity of ventricular premature beats (VPBs) in adults without apparent heart disease. The number of types of VPBs seem in 5% or less were considered 'abnormal' and th...

journal_title：European heart journal

authors： Bjerregaard P,Sorensen KE,Molgaard H

更新日期：1991-05-01 00:00:00

abstract：AIMS:microRNA (miRNA) is reported to be present in the blood of humans and has been increasingly suggested as a biomarker for diseases. We aim to determine the potential of cardiac-specific miRNAs in circulation to serve as biomarkers for acute myocardial infarction (AMI). METHODS AND RESULTS:By verifying their tissue...

journal_title：European heart journal

authors： Wang GK,Zhu JQ,Zhang JT,Li Q,Li Y,He J,Qin YW,Jing Q

更新日期：2010-03-01 00:00:00

abstract：:Aims To explore the cost-effectiveness of alternative methods of screening family members for hypertrophic cardiomyopathy (HCM), the most common monogenic cardiac disorder and the most frequent cause of sudden cardiac death (SCD) in young people. Methods and results Economic decision model comparing cascade screening ...

journal_title：European heart journal

authors： Wordsworth S,Leal J,Blair E,Legood R,Thomson K,Seller A,Taylor J,Watkins H

更新日期：2010-04-01 00:00:00

abstract：AIMS:In patients with Marfan syndrome and other type-1 fibrillinopathies, genetic testing is becoming more easily available, leading to the identification of mutations early in the course of the disease. This study evaluates the cardiovascular (CV) risk associated with the discovery of a fibrillin-1 (FBN1) mutation. M...

journal_title：European heart journal

authors： Détaint D,Faivre L,Collod-Beroud G,Child AH,Loeys BL,Binquet C,Gautier E,Arbustini E,Mayer K,Arslan-Kirchner M,Stheneur C,Halliday D,Beroud C,Bonithon-Kopp C,Claustres M,Plauchu H,Robinson PN,Kiotsekoglou A,De Backer

更新日期：2010-09-01 00:00:00

abstract：AIMS:Adverse left ventricular (LV) remodelling after myocardial infarction (MI) frequently leads to congestive heart failure (CHF). We have previously shown that myocardial beta-adrenoceptor density (beta-ARD) is reduced soon after acute MI and correlates with LV dilatation in the short term. The aim of the present stu...

journal_title：European heart journal

authors： Gaemperli O,Liga R,Spyrou N,Rosen SD,Foale R,Kooner JS,Rimoldi OE,Camici PG

更新日期：2010-07-01 00:00:00

abstract：AIMS:Aortic stenosis causes cardiac hypertrophy and fibrosis, which often persists despite pressure unloading after aortic valve replacement. The persistence of myocardial fibrosis in particular leads to impaired cardiac function and increased mortality. We investigated whether granulocyte colony-stimulating factor (G-...

journal_title：European heart journal

authors： Szardien S,Nef HM,Voss S,Troidl C,Liebetrau C,Hoffmann J,Rauch M,Mayer K,Kimmich K,Rolf A,Rixe J,Troidl K,Kojonazarov B,Schermuly RT,Kostin S,Elsässer A,Hamm CW,Möllmann H

更新日期：2012-03-01 00:00:00

abstract：AIMS:The risk of stroke is greater among women with atrial fibrillation (AF) than men. Warfarin protects against stroke, but treatment-related bleeding occurs more often in women than in men. METHODS AND RESULTS:SPORTIF III (open label, n=3410) and V (double-blind, n=3922) included 2257 women with AF and one or more s...

journal_title：European heart journal

authors： Gomberg-Maitland M,Wenger NK,Feyzi J,Lengyel M,Volgman AS,Petersen P,Frison L,Halperin JL

更新日期：2006-08-01 00:00:00