Lack of benefit from percutaneous intervention of persistently occluded infarct arteries after the acute phase of myocardial infarction is time independent: insights from Occluded Artery Trial.

Abstract:

AIMS:The Occluded Artery Trial (OAT) (n = 2201) showed no benefit for routine percutaneous intervention (PCI) (n = 1101) over medical therapy (MED) (n = 1100) on the combined endpoint of death, myocardial infarction (MI), and class IV heart failure (congestive heart failure) in stable post-MI patients with late occluded infarct-related arteries (IRAs). We evaluated the potential for selective benefit with PCI over MED for patients enrolled early in OAT. METHODS AND RESULTS:We explored outcomes with PCI over MED in patients randomized to the

journal_name

Eur Heart J

journal_title

European heart journal

authors

Menon V,Pearte CA,Buller CE,Steg PG,Forman SA,White HD,Marino PN,Katritsis DG,Caramori P,Lasevitch R,Loboz-Grudzien K,Zurakowski A,Lamas GA,Hochman JS

doi

10.1093/eurheartj/ehn486

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

183-91

issue

2

eissn

0195-668X

issn

1522-9645

pii

ehn486

journal_volume

30

pub_type

杂志文章,随机对照试验
  • Acute effects of night-time noise exposure on blood pressure in populations living near airports.

    abstract:AIMS:Within the framework of the HYENA (hypertension and exposure to noise near airports) project we investigated the effect of short-term changes of transportation or indoor noise levels on blood pressure (BP) and heart rate (HR) during night-time sleep in 140 subjects living near four major European airports. METHOD...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehn013

    authors: Haralabidis AS,Dimakopoulou K,Vigna-Taglianti F,Giampaolo M,Borgini A,Dudley ML,Pershagen G,Bluhm G,Houthuijs D,Babisch W,Velonakis M,Katsouyanni K,Jarup L,HYENA Consortium.

    更新日期:2008-03-01 00:00:00

  • Reactivation of coagulation after stopping infusions of recombinant hirudin and unfractionated heparin in unstable angina and myocardial infarction without ST elevation: results of a randomized trial. OASIS Pilot Study Investigators. Organization to Asses

    abstract:AIMS:To compare effects of heparin and hirudin on biochemical markers of coagulation. METHODS AND RESULTS:Patients (n=395) with unstable angina or myocardial infarction without ST elevation were randomized to a 72-h infusion of one of three regimens: unfractionated heparin (bolus of 5000 IU followed by an infusion of ...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1053/euhj.1999.2005

    authors: Flather MD,Weitz JI,Yusuf S,Pogue J,Sussex B,Campeau J,Gill J,Schuld R,Joyner CD,Morris AL,Lai C,Théroux P,Marquis JF,Chan YK,Venkatesh G,Jessel A

    更新日期:2000-09-01 00:00:00

  • Correlation between inducibility of sustained ventricular tachycardia and QRS duration.

    abstract::Some studies provide a link between the width of QRS complexes and late potentials occurring at the end of the QRS complex in signal-averaged recordings. The purpose of this study was to compare three methods of QRS duration measurement: the conventional 12 lead ECG, the Frank vectorcardiogram (VCG) and the signal-ave...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a060375

    authors: Brembilla-Perrot B

    更新日期:1994-01-01 00:00:00

  • Sex-dependent differences in left ventricular function and structure in chronic pressure overload.

    abstract::To evaluate gender-related differences in left ventricular (LV) structure and function in aortic stenosis, LV biplane cineangiography, micromanometry and endomyocardial biopsies were carried out in 56 patients with aortic stenosis and normal coronary arteries. Patients were divided into males (M: n = 35), and females ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a060749

    authors: Villari B,Campbell SE,Schneider J,Vassalli G,Chiariello M,Hess OM

    更新日期:1995-10-01 00:00:00

  • C-reactive protein, infarct size, microvascular obstruction, and left-ventricular remodelling following acute myocardial infarction.

    abstract:AIMS:This study assessed the relationship between inflammatory mediators and indices of infarct size and left-ventricular (LV) remodelling following successful primary percutaneous coronary intervention (PCI) in patients with first time ST elevation myocardial infarction (MI). METHODS AND RESULTS:Forty-two patients ad...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehp070

    authors: Ørn S,Manhenke C,Ueland T,Damås JK,Mollnes TE,Edvardsen T,Aukrust P,Dickstein K

    更新日期:2009-05-01 00:00:00

  • Comparison of the effects of two doses of bisoprolol on exercise tolerance in exercise-induced stable angina pectoris.

    abstract::Recently, bisoprolol has been investigated regarding its effects on exercise tolerance and the duration of action in patients with coronary heart disease (CHD) following single oral administration. It appears, however, that the extent of effects of 5 mg bisoprolol is not fully established yet. Therefore, the effects o...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/eurheartj/8.suppl_m.31

    authors: de Muinck E,Wagner G,vd Ven LL,Lie KI

    更新日期:1987-12-01 00:00:00

  • Association of fetuin-A levels with the progression of aortic valve calcification in non-dialyzed patients.

    abstract:AIMS:Fetuin-A has been identified as a potent circulating inhibitor of ectopic calcification. We investigated the relationship between baseline fetuin-A serum levels and the rate of progression of aortic valve calcification (AVC) in non-dialyzed patients with aortic valve disease (AVD). METHODS AND RESULTS:Seventy-sev...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehp158

    authors: Koos R,Brandenburg V,Mahnken AH,Mühlenbruch G,Stanzel S,Günther RW,Floege J,Jahnen-Dechent W,Kelm M,Kühl HP

    更新日期:2009-08-01 00:00:00

  • Differential change in left ventricular mass and regional wall thickness after cardiac resynchronization therapy for heart failure.

    abstract:AIMS:LV reverse remodelling has been shown to be a favourable response after cardiac resynchronization therapy (CRT) in many clinical trials. This study investigated whether left ventricular (LV) reverse remodelling after CRT has any structural benefit, which include the improvement of LV mass or regional wall thicknes...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehi885

    authors: Zhang Q,Fung JW,Auricchio A,Chan JY,Kum LC,Wu LW,Yu CM

    更新日期:2006-06-01 00:00:00

  • CD14++CD16+ monocytes and cardiovascular outcome in patients with chronic kidney disease.

    abstract:AIMS:Patients with chronic kidney disease (CKD) pose a worldwide growing burden to health care systems due to accelerated atherosclerosis and subsequent high cardiovascular (CV) morbidity. Atherogenesis is prominently driven by monocytes and monocyte-derived macrophages. The expression of CD14 and CD16 characterizes th...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehq371

    authors: Rogacev KS,Seiler S,Zawada AM,Reichart B,Herath E,Roth D,Ulrich C,Fliser D,Heine GH

    更新日期:2011-01-01 00:00:00

  • Atrial pacing for suppression of early reinitiation of atrial fibrillation after successful internal cardioversion.

    abstract:AIMS:To evaluate the efficacy of atrial pacing in the suppression of early reinitiation of atrial fibrillation after successful internal cardioversion. METHODS AND RESULTS:The efficacy of atrial pacing in suppressing early reinitiation of atrial fibrillation was studied in 12 of 45 (29%) patients with early reinitiati...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章

    doi:10.1053/euhj.1999.1991

    authors: Tse HF,Lau CP,Ayers GM

    更新日期:2000-07-01 00:00:00

  • Quantification of beta-adrenoceptors and beta-adrenoceptor kinase on protein and mRNA levels in heart failure.

    abstract::The alterations of the beta-adrenoceptor adenylyl cyclase are reviewed. In failing myocardium, the down-regulation of beta 1-adrenoceptors is accompanied by a decrease in steady state mRNA levels, as studied with quantitative polymerase chain reactions in dilated and ischaemic cardiomyopathy. The density of beta 2-adr...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/15.suppl_d.30

    authors: Böhm M,Lohse MJ

    更新日期:1994-12-01 00:00:00

  • Head to head comparison of dobutamine-transoesophageal echocardiography and dobutamine-magnetic resonance imaging for the prediction of left ventricular functional recovery in patients with chronic coronary artery disease.

    abstract:AIMS:A substantial number of patients with dysfunctional but potentially viable myocardium cannot be accurately evaluated by transthoracic echocardiography due to a poor acoustic window. This study compares the diagnostic value of alternative functional imaging techniques, such as dobutamine-transoesophageal echocardio...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1053/euhj.2000.1946

    authors: Baer FM,Theissen P,Crnac J,Schmidt M,Deutsch HJ,Sechtem U,Schicha H,Erdmann E

    更新日期:2000-06-01 00:00:00

  • Diabetes clinical trials: helped or hindered by the current shift in regulatory requirements?

    abstract::Glycaemic control is an inadequate surrogate marker of cardiovascular event reduction in patients with type 2 diabetes. Clinical trials to date have been unsuccessful in identifying a therapeutic approach that addresses the underlying problem in diabetes (glycaemic control) and reduces cardiovascular risk. The potenti...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/ehr437

    authors: Zannad F,Stough WG,Pocock SJ,Sleight P,Cushman WC,Cleland JG,McMurray JJ,Lonn E,Geller NL,Wedel H,Abadie E,Alonso-Garcia A,Pitt B

    更新日期:2012-05-01 00:00:00

  • Association of competitive and recreational sport participation with cardiac events in patients with arrhythmogenic right ventricular cardiomyopathy: results from the North American multidisciplinary study of arrhythmogenic right ventricular cardiomyopath

    abstract:AIMS:It has been proposed that competitive sport increases the risk of ventricular tachyarrhythmias (VTA) and death in patients with arrhythmogenic right-ventricular cardiomyopathy (ARVC). However, it is unknown whether this only applies to competitive sport or if recreational sports activity also increases the risk of...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章

    doi:10.1093/eurheartj/ehv110

    authors: Ruwald AC,Marcus F,Estes NA 3rd,Link M,McNitt S,Polonsky B,Calkins H,Towbin JA,Moss AJ,Zareba W

    更新日期:2015-07-14 00:00:00

  • Relations of plasma total TIMP-1 levels to cardiovascular risk factors and echocardiographic measures: the Framingham heart study.

    abstract:AIMS:Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a key regulator of extracellular matrix degradation. We examined relations of plasma total TIMP-1 to cardiovascular risk factors and echocardiographic left ventricular (LV) structure and function in a community-based sample. METHODS AND RESULTS:We studied 1069 ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ehj.2004.05.029

    authors: Sundström J,Evans JC,Benjamin EJ,Levy D,Larson MG,Sawyer DB,Siwik DA,Colucci WS,Wilson PW,Vasan RS

    更新日期:2004-09-01 00:00:00

  • Health economic consequences of the pharmacological treatment of heart failure.

    abstract::Health economics is about spending limited resources wisely and, as with so many fields in medicine, combines science with art and ingenuity. In order to know whether money is well spent it is necessary to have some reference points to make comparisons. Many accepted cardiovascular interventions, such as revasculariza...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:

    authors: Cleland JG

    更新日期:1998-12-01 00:00:00

  • Stent thrombosis and restenosis: what have we learned and where are we going? The Andreas Grüntzig Lecture ESC 2014.

    abstract::Modern-day stenting procedures leverage advances in pharmacotherapy and device innovation. Patients treated with contemporary antiplatelet agents, peri-procedural antithrombin therapy and new-generation drug-eluting stents (DES) have excellent outcomes over the short to medium term. Indeed, coupled with the reducing c...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/ehv511

    authors: Byrne RA,Joner M,Kastrati A

    更新日期:2015-12-14 00:00:00

  • Infarct size, left ventricular function, and prognosis in women compared to men after primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: results from an individual patient-level pooled analysis of 10 randomized trial

    abstract:Aim:Studies have reported less favourable outcomes in women compared with men after primary percutaneous coronary intervention (PCI) in ST-segment elevation myocardial infarction (STEMI). Whether sex-specific differences in the magnitude or prognostic impact of infarct size or post-infarction cardiac function explain t...

    journal_title:European heart journal

    pub_type: 杂志文章,meta分析,评审

    doi:10.1093/eurheartj/ehx159

    authors: Kosmidou I,Redfors B,Selker HP,Thiele H,Patel MR,Udelson JE,Magnus Ohman E,Eitel I,Granger CB,Maehara A,Kirtane A,Généreux P,Jenkins PL,Ben-Yehuda O,Mintz GS,Stone GW

    更新日期:2017-06-01 00:00:00

  • Circulating angiopoietins in idiopathic pulmonary arterial hypertension.

    abstract:AIMS:To determine the diagnostic utility of circulating angiopoietin-1 (Ang-1) and its antagonist angiopoietin-2 (Ang-2) as potential biomarkers of disease severity or response to treatment in idiopathic pulmonary arterial hypertension (IPAH). Imbalances in angiogenic factors including vascular endothelial cell growth ...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehq226

    authors: Kümpers P,Nickel N,Lukasz A,Golpon H,Westerkamp V,Olsson KM,Jonigk D,Maegel L,Bockmeyer CL,David S,Hoeper MM

    更新日期:2010-09-01 00:00:00

  • No effect of PCSK9 inhibitor alirocumab on the incidence of diabetes in a pooled analysis from 10 ODYSSEY Phase 3 studies.

    abstract:AIMS:Statins have modest adverse effects on glycaemic control. Alirocumab, a proprotein convertase subtilisin/kexin type 9 inhibitor, lowers low-density lipoprotein cholesterol. This study assessed the effects of alirocumab on new-onset diabetes and pre-diabetes incidence in individuals without diabetes at baseline. M...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehw292

    authors: Colhoun HM,Ginsberg HN,Robinson JG,Leiter LA,Müller-Wieland D,Henry RR,Cariou B,Baccara-Dinet MT,Pordy R,Merlet L,Eckel RH

    更新日期:2016-10-14 00:00:00

  • Practical aspects of preventing and managing athersclerotic disease in post-menopausal women.

    abstract::Factors that exacerbate the risk of atherosclerotic plaque formation include cigarette smoking, hypertension, hypercholesterolaemia, sedentary lifestyle, and oestrogen deficiency. The potentially important role of oestrogen deficiency in this process is evidenced by the significant increase in cardiovascular risk obse...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/17.suppl_d.32

    authors: Sullivan JM

    更新日期:1996-08-01 00:00:00

  • Triiodothyronine therapy in open-heart surgery: from hope to disappointment.

    abstract::A controversy persists as to whether cardiopulmonary bypass (CPB) decreases plasma levels of triiodothyronine (T3), thereby justifying peri-operative administration of T3 to improve haemodynamic recovery. To examine the effects of T3 therapy on post-CPB haemodynamics and to determine whether the potential inotropic ef...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/eurheartj/14.5.629

    authors: Teiger E,Menasché P,Mansier P,Chevalier B,Lajeunie E,Bloch G,Piwnica A

    更新日期:1993-05-01 00:00:00

  • Omics phenotyping in heart failure: the next frontier.

    abstract::This state-of-the-art review aims to provide an up-to-date look at breakthrough omic technologies that are helping to unravel heart failure (HF) disease mechanisms and heterogeneity. Genomics, transcriptomics, proteomics, and metabolomics in HF are reviewed in depth. In addition, there is a thorough, expert discussion...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehaa270

    authors: Bayes-Genis A,Liu PP,Lanfear DE,de Boer RA,González A,Thum T,Emdin M,Januzzi JL

    更新日期:2020-09-21 00:00:00

  • Association of growth differentiation factor 11/8, putative anti-ageing factor, with cardiovascular outcomes and overall mortality in humans: analysis of the Heart and Soul and HUNT3 cohorts.

    abstract:AIMS:Growth differentiation factor 11 and/or its homologue growth differentiation factor 8 (GDF11/8) reverses age-related cardiac hypertrophy and vascular ageing in mice. We investigated whether GDF11/8 associates with cardiovascular outcomes, left ventricular hypertrophy (LVH), or age in humans. METHODS AND RESULTS:W...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1093/eurheartj/ehv385

    authors: Olson KA,Beatty AL,Heidecker B,Regan MC,Brody EN,Foreman T,Kato S,Mehler RE,Singer BS,Hveem K,Dalen H,Sterling DG,Lawn RM,Schiller NB,Williams SA,Whooley MA,Ganz P

    更新日期:2015-12-21 00:00:00

  • Endothelium-derived nitric oxide: the endogenous nitrovasodilator in the human cardiovascular system.

    abstract::The L-arginine pathway within endothelial cells in the blood vessel wall is the source of production of the endogenous nitrovasodilator, nitric oxide (NO). NO is released under basal conditions and in response to various stimuli such as shear stress and in response to platelet-derived products, coagulation factors and...

    journal_title:European heart journal

    pub_type: 杂志文章,评审

    doi:10.1093/eurheartj/12.suppl_e.2

    authors: Lüscher TF

    更新日期:1991-11-01 00:00:00

  • Creatine kinase-MB elevation after percutaneous coronary intervention predicts adverse outcomes in patients with acute coronary syndromes.

    abstract:AIM:To study the relationship between outcomes and peak creatine kinase (CK)-MB levels after percutaneous coronary intervention (PCI) in patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS). METHODS AND RESULTS:Peak CK-MB ratios (peak CK-MB level/upper limit of normal [ULN]) after PCI were analys...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.ehj.2003.12.009

    authors: Roe MT,Mahaffey KW,Kilaru R,Alexander JH,Akkerhuis KM,Simoons ML,Harrington RA,Tardiff BE,Granger CB,Ohman EM,Moliterno DJ,Lincoff AM,Armstrong PW,Van de Werf F,Califf RM,Topol EJ

    更新日期:2004-02-01 00:00:00

  • Left ventricular filling after long-term angiotensin converting enzyme inhibition in congestive heart failure.

    abstract::As a rule, left ventricular relaxation is impaired in patients with coronary artery disease and congestive heart failure. In addition, the passive elastic properties in early and late diastole change when the ventricle dilates. Diastolic properties of the left ventricle were studied in 11 patients with congestive hear...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/13.suppl_e.52

    authors: Baur LH,Schipperheyn JJ,Cats VM,van der Wall EE,Baan J,van Dijk AD,Bruschke AV

    更新日期:1992-11-01 00:00:00

  • Plasma concentrations of platelet-specific proteins in young female acute myocardial infarction survivors and their age-matched female controls.

    abstract::The steady state plasma concentrations of the two platelet-specific proteins beta-thromboglobulin (BTG) and platelet factor 4 (PF4) were determined in two groups of females: 36 acute myocardial infarction (AMI) survivors, and 38 age-matched control subjects. For the AMI patients the mean BTG and PF4 values were 57 +/-...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a061465

    authors: Kutti J,Johansson S,Eriksson KA,Sigvaldason A,Vedin A,Wadenvik H,Wilhelmsson C

    更新日期:1983-05-01 00:00:00

  • Regional myocardial deformation in children with hypertrophic cardiomyopathy: morphological and clinical correlations.

    abstract:AIMS:Hypertrophic cardiomyopathy (HCM) is a disease with marked regional differences in wall thickness. However, the relation between myocardial function and wall thickness has not been well studied. Ultrasonic strain rate (SR) imaging makes it possible to study the regional myocardial deformation. We investigated whet...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/eurheartj/ehm444

    authors: Ganame J,Mertens L,Eidem BW,Claus P,D'hooge J,Havemann LM,McMahon CJ,Elayda MA,Vaughn WK,Towbin JA,Ayres NA,Pignatelli RH

    更新日期:2007-12-01 00:00:00

  • Subaortic aneurysm of the left ventricle obstructing a coronary artery.

    abstract::We report a subaortic aneurysm of the left ventricle causing compression of a coronary artery in a 52-year-old white man presenting with angina on effort. Endocarditis seemed to be implicated as the cause of this rare condition. To what extent coronary obstruction influenced the development of myocardial ischaemia was...

    journal_title:European heart journal

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.eurheartj.a062318

    authors: Bartorelli A,Sala A

    更新日期:1987-05-01 00:00:00