Endothelium-derived nitric oxide: the endogenous nitrovasodilator in the human cardiovascular system.

abstract：AIMS:Cardiac angiotensin-I converting enzyme (ACE) activity is influenced by the ACE I/D polymorphism. Evidence suggests that the DD-genotype may be a risk factor for cardiac hypertrophy and heart failure, especially in hypertensive subjects. We assessed the relation between the ACE I/D polymorphism and the risk of inc...

journal_title：European heart journal

authors： Schut AF,Bleumink GS,Stricker BH,Hofman A,Witteman JC,Pols HA,Deckers JW,Deinum J,van Duijn CM

更新日期：2004-12-01 00:00:00

abstract：:Physical fitness of athletes affected by mitral valve prolapse (MVP) was examined, in order to evaluate the influence of sport activity on the natural history of the disease. Maximal workload, total workload, percentage efficiency (according to Hollmann's formula), double product of maximal cycloergometric stress test...

journal_title：European heart journal

authors： Musante R,Cupelli V,Mori F,Attinà DA

更新日期：1987-08-01 00:00:00

abstract：Aims:To determine tolerability and the optimal dose regimen of the soluble guanylate cyclase stimulator vericiguat in patients with chronic heart failure and preserved ejection fraction (HFpEF). Methods and results:SOCRATES-PRESERVED was a prospective, randomized, placebo-controlled double-blind, Phase 2b dose-finding...

journal_title：European heart journal

authors： Pieske B,Maggioni AP,Lam CSP,Pieske-Kraigher E,Filippatos G,Butler J,Ponikowski P,Shah SJ,Solomon SD,Scalise AV,Mueller K,Roessig L,Gheorghiade M

更新日期：2017-04-14 00:00:00

abstract：AIMS:Chronic kidney disease is directly associated with cardiovascular complications. Heart remodelling, including fibrosis, hypertrophy, and decreased vascularization, is frequently present in renal diseases. Our objective was to investigate the impact of calcineurin inhibitors (CNI) on cardiac remodelling and functio...

journal_title：European heart journal

authors： Di Marco GS,Reuter S,Kentrup D,Ting L,Ting L,Grabner A,Jacobi AM,Pavenstädt H,Baba HA,Tiemann K,Brand M

更新日期：2011-08-01 00:00:00

abstract：:From a clinicopharmacological standpoint, the urinary excretory potency of diuretics should be assessed comparatively, on the basis of placebo-controlled changes in 24 h natriuresis, following single oral doses administered to healthy adult subjects who are in steady-state habitual external sodium balance. The potency...

journal_title：European heart journal

authors： Reyes AJ

更新日期：1992-12-01 00:00:00

abstract：AIMS:To investigate whether Atorvastatin (Ator) treatment improves the cardiac micro-environment that facilitates survival and differentiation of bone-marrow-derived mesenchymal stem cells (MSCs) implanted in the post-infarct myocardium. METHODS AND RESULTS:Myocardial infarction was created by coronary ligation and im...

journal_title：European heart journal

authors： Yang YJ,Qian HY,Huang J,Geng YJ,Gao RL,Dou KF,Yang GS,Li JJ,Shen R,He ZX,Lu MJ,Zhao SH

更新日期：2008-06-01 00:00:00

abstract：:Eight young healthy male subjects, members of a Himalayan expedition, underwent 24 h Holter monitoring before departure, after 1 and 4 weeks at high altitude (5000 m) and after return to sea level. At high altitude, the circadian reciprocal changes in low and high frequency (LF, HF) were absent, with no significant re...

journal_title：European heart journal

authors： Ponchia A,Noventa D,Bertaglia M,Carretta R,Zaccaria M,Miraglia G,Pascotto P,Buja G

更新日期：1994-11-01 00:00:00

abstract：:Eleven patients with an atrioventricular accessory pathway were studied by programmed electrical stimulation to determine if reentrant tachycardia could be prevented by delivery of either a single atrial extrastimulus, applied at a critical time after the tachycardia-initiating stimulus (or stimuli), or a train of sti...

journal_title：European heart journal

authors： Kuck KH,Kunze KP,Schlüter M,Bleifeld W

更新日期：1985-01-01 00:00:00

abstract：:Recently, it has been suggested that oxidized low density lipoprotein (LDL) plays an important role in atherogenesis by facilitating the accumulation of lipids in macrophages. In vitro studies from our laboratory have shown that oxidized LDL is recognized not only by a specific receptor, but also by a receptor which r...

journal_title：European heart journal

authors： Kita T,Ishii K,Yokode M,Kume N,Nagano Y,Arai H,Kawai C

更新日期：1990-08-01 00:00:00

abstract：AIMS:Efficacy of aspirin in primary prevention of cardiovascular disease (CVD) may be influenced by a common allele in guanylate cyclase GUCY1A3, which has been shown to modify platelet function and increase CVD risk. METHODS AND RESULTS:We investigated whether homozygotes of the GUCY1A3 rs7692387 risk (G) allele bene...

journal_title：European heart journal

authors： Hall KT,Kessler T,Buring JE,Passow D,Sesso HD,Zee RYL,Ridker PM,Chasman DI,Schunkert H

更新日期：2019-11-01 00:00:00

abstract：:Increased QT dispersion, which has been proposed as a marker of ventricular repolarization inhomogeneity, may predispose to ventricular arrhythmias. Data on QT dispersion in patients with congestive heart failure are scarce. In this study, conventional 12-lead ECGs were recorded in 135 consecutive patients with conges...

journal_title：European heart journal

authors： Fei L,Goldman JH,Prasad K,Keeling PJ,Reardon K,Camm AJ,McKenna WJ

更新日期：1996-02-01 00:00:00

abstract：:A major challenge for all health care systems is to identify the most efficient use of limited and finite resources available for health care. Economic evaluation provides a balance sheet of the benefits, harms and costs for making choices between alternative health care services and is one strategy to assist decision...

journal_title：European heart journal

authors： Oldridge NB

更新日期：1998-11-01 00:00:00

abstract：:In 13 patients with chronic stable angina, left ventricular pressures were measured by catheter-tip micromanometer, and left cineventriculography was performed at matched atrial paced rates before and 20 min after administration of intravenous gallopamil (3 mg). Mean plasma concentration of gallopamil at the second ha...

journal_title：European heart journal

authors： Di Mario C,Iavernaro A,Cucchini F

更新日期：1991-09-01 00:00:00

abstract：Aims:Bioresorbable scaffolds (BRS) provide short-term coronary artery scaffolding and drug delivery. Although prior trials showed a higher rate of device failure compared with conventional drug-eluting stents (DES), only a single trial investigated patients undergoing percutaneous coronary intervention (PCI) for acute ...

journal_title：European heart journal

authors： Byrne RA,Alfonso F,Schneider S,Maeng M,Wiebe J,Kretov E,Bradaric C,Rai H,Cuesta J,Rivero F,Hoppmann P,Schlichtenmaier J,Christiansen EH,Cassese S,Joner M,Schunkert H,Laugwitz KL,Kastrati A

更新日期：2019-01-07 00:00:00

abstract：OBJECTIVE:The purpose of this study was to determine the sensitivity and specificity of new criteria proposed by Duke University for case definition of infective endocarditis as compared to the previously accepted Von Reyn criteria. PATIENTS:A total of 143 consecutive suspected cases of infective endocarditis in 137 f...

journal_title：European heart journal

authors： Cecchi E,Parrini I,Chinaglia A,Pomari F,Brusasco G,Bobbio M,Trinchero R,Brusca A

更新日期：1997-07-01 00:00:00

abstract：AIMS:In Belgium, general practitioners (GPs) mainly manage oral anticoagulation therapy. To improve the quality of oral anticoagulation management by GPs and to compare different models and interventions, a randomized clinical trial was performed. METHODS AND RESULTS:Stratified randomization divided 66 GP-practices in...

journal_title：European heart journal

authors： Claes N,Buntinx F,Vijgen J,Arnout J,Vermylen J,Fieuws S,Van Loon H

更新日期：2005-10-01 00:00:00

abstract：:The prevalence and type of arrhythmias has been studied in a representative sample of 2000 Athenians, aged 18-81 years, who underwent exercise testing on a treadmill according to the Bruce protocol. It was found that 121 persons (mean age 55.7 +/- 14.9 years, 31% greater than 65 years), exhibited arrhythmias on the EC...

journal_title：European heart journal

authors： Diamantopoulos EJ,Anthopoulos L,Nanas S,Maliaras G,Chrisos D,Moulopoulos SD

更新日期：1987-08-01 00:00:00

abstract：AIM:Few epidemiological data are available describing the sudden death of persons in their prime. This study aims to elucidate when and how sudden death occurs among employees. METHODS:A total of 196775 employees from 10 workplaces in Central Japan were surveyed for non-traumatic sudden death during 1989-1995. Demogra...

journal_title：European heart journal

authors： Kawamura T,Kondo H,Hirai M,Wakai K,Tamakoshi A,Terazawa T,Osugi S,Ohno M,Okamoto N,Tsuchida T,Ohno Y,Toyama J

更新日期：1999-03-01 00:00:00

abstract：AIMS:The management and outcomes of patients with functional moderate/severe mitral regurgitation and severe left ventricular (LV) systolic dysfunction are not well defined. We sought to determine the characteristics, management strategies, and outcomes of patients with moderate or severe mitral regurgitation (MR) and ...

journal_title：European heart journal

authors： Samad Z,Shaw LK,Phelan M,Ersboll M,Risum N,Al-Khalidi HR,Glower DD,Milano CA,Alexander JH,O'Connor CM,Wang A,Velazquez EJ

更新日期：2015-10-21 00:00:00

abstract：AIMS:The combined use of cardiac computed tomography (CT) coronary angiography (CTCA) and myocardial perfusion imaging allows the non-invasive evaluation of coronary morphology and function. Cardiovascular magnetic resonance (CMR) imaging has several advantages: it can simultaneously assess myocardial perfusion, ventri...

journal_title：European heart journal

authors： Groothuis JG,Beek AM,Brinckman SL,Meijerink MR,van den Oever ML,Hofman MB,van Kuijk C,van Rossum AC

更新日期：2013-07-01 00:00:00

abstract：AIMS:Atrial fibrillation (AF) occurs often in patients after coronary artery bypass grafting (CABG) and can result in increased morbidity and mortality. Previous studies using P-wave signal-averaged electrocardiogram (P-SAECG) have shown that patients with a longer filtered P-wave duration (FPD) have a high risk of AF ...

journal_title：European heart journal

authors： Budeus M,Hennersdorf M,Perings S,Röhlen S,Schnitzler S,Felix O,Reimert K,Feindt P,Gams E,Lehmann N,Wieneke H,Sack S,Erbel R,Perings C

更新日期：2006-07-01 00:00:00

abstract：:Patients who have an accessory pathway (AP) of atrioventricular (AV) conduction may develop circus movement tachycardia otherwise known as atrioventricular re-entrant tachycardia (AVRT). Orthodromic AVRT is the most common form. It occurs as a result of antegrade conduction through the normal AV conduction system and ...

journal_title：European heart journal

authors： Obel OA,Camm AJ

更新日期：1998-05-01 00:00:00

abstract：AIMS:To investigate the efficacy and outcome of emergency percutaneous coronary interventions (PCI) in patients with stent thrombosis. METHODS AND RESULTS:Between 1995 and 2003, 6058 patients underwent bare-metal stent implantation, of which 95 (1.6%) patients suffered from stent thrombosis. The timing of stent thromb...

journal_title：European heart journal

authors： Wenaweser P,Rey C,Eberli FR,Togni M,Tüller D,Locher S,Remondino A,Seiler C,Hess OM,Meier B,Windecker S

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Sixteen cases of sudden unexpected cardiac death, 15 males and one female, are known to have occurred among young Swedish orienteers from 1979 to 1992, of which seven cases occurred between 1989 and 1992. This is considered to be indicative of an increased death rate. RESULTS:Histopathological evaluation sh...

journal_title：European heart journal

authors： Wesslén L,Påhlson C,Lindquist O,Hjelm E,Gnarpe J,Larsson E,Baandrup U,Eriksson L,Fohlman J,Engstrand L,Linglöf T,Nyström-Rosander C,Gnarpe H,Magnius L,Rolf C,Friman G

更新日期：1996-06-01 00:00:00

abstract：:We investigated whether left ventricular hypertrophy in elite cyclists is associated with functional changes or abnormal energy metabolism. Left ventricular hypertrophy is a powerful risk factor for sudden cardiac death with different prognostic significance among the various geometric forms. Cyclists may have a combi...

journal_title：European heart journal

authors： Pluim BM,Chin JC,De Roos A,Doornbos J,Siebelink HM,Van der Laarse A,Vliegen HW,Lamerichs RM,Bruschke AV,Van der Wall EE

更新日期：1996-08-01 00:00:00

abstract：:A previously described nitroglycerin-induced heparin resistance could not be verified by in-vitro experiments or in a randomized, double-blind, crossover trial in healthy volunteers. A clinically relevant attenuation of the anticoagulant effect of a heparin bolus (40 U.kg-1) by a concomitant infusion of nitroglycerin ...

journal_title：European heart journal

authors： Schoenenberger RA,Ménat L,Weiss P,Marbet GA,Ritz R

更新日期：1992-03-01 00:00:00

abstract：:Recently, bisoprolol has been investigated regarding its effects on exercise tolerance and the duration of action in patients with coronary heart disease (CHD) following single oral administration. It appears, however, that the extent of effects of 5 mg bisoprolol is not fully established yet. Therefore, the effects o...

journal_title：European heart journal

authors： de Muinck E,Wagner G,vd Ven LL,Lie KI

更新日期：1987-12-01 00:00:00

abstract：:A 55-year-old woman presented with fever and malaise. Three blood cultures were positive for Streptococcus sanguis. A diagnosis of endocarditis was made and the patient was treated with intravenous penicillin and gentamicin. Endocardiography revealed a large left atrial tumour. At operation a myxoma covered by deposit...

journal_title：European heart journal

authors： ten Berg JM,Elbers HR,Defauw JJ,Plokker HW

更新日期：1992-11-01 00:00:00

abstract：AIMS:In patients with sick sinus syndrome, bradycardia can be treated with a single-lead pacemaker or a dual-chamber pacemaker. Previous trials have revealed that pacing modes preserving atrio-ventricular synchrony are superior to single-lead ventricular pacing, but it remains unclear if there is any difference between...

journal_title：European heart journal

authors： Nielsen JC,Thomsen PE,Højberg S,Møller M,Vesterlund T,Dalsgaard D,Mortensen LS,Nielsen T,Asklund M,Friis EV,Christensen PD,Simonsen EH,Eriksen UH,Jensen GV,Svendsen JH,Toff WD,Healey JS,Andersen HR,DANPACE Investigato

更新日期：2011-03-01 00:00:00

abstract：:Nucleic acid-based therapeutics are currently developed at large scale for prevention and management of cardiovascular diseases (CVDs), since: (i) genetic studies have highlighted novel therapeutic targets suggested to be causal for CVD; (ii) there is a substantial recent progress in delivery, efficacy, and safety of ...

journal_title：European heart journal

authors： Landmesser U,Poller W,Tsimikas S,Most P,Paneni F,Lüscher TF

更新日期：2020-10-21 00:00:00