Experimental evidence for beta adrenergic blocking properties of propafenone and for their potential clinical relevance.

abstract：AIMS:We investigated the role of asymmetric dimethylarginine (ADMA) for clinical outcome of patients with unstable angina. METHODS AND RESULTS:Forty-five patients with stable angina, 36 patients with unstable angina, and 40 healthy controls were included in this study. Coronary artery disease (CAD) patients were prosp...

journal_title：European heart journal

authors： Krempl TK,Maas R,Sydow K,Meinertz T,Böger RH,Kähler J

更新日期：2005-09-01 00:00:00

abstract：AIMS:Cigarette smoking is a well-established risk factor for cardiovascular disease yet several studies have shown lower mortality after acute coronary syndromes in smokers compared with non-smokers, the so called 'smoker's paradox'. This study aimed to ascertain the relationship between smoking and clinical outcomes i...

journal_title：European heart journal

authors： Fonarow GC,Abraham WT,Albert NM,Stough WG,Gheorghiade M,Greenberg BH,O'Connor CM,Nunez E,Yancy CW,Young JB

更新日期：2008-08-01 00:00:00

abstract：:Stress echocardiography is an established method for the diagnosis and prognostic stratification of coronary artery disease. In the last few years, the tremendous technological and conceptual versatility of this technique has been increasingly applied in challenging diagnostic fields. Today, in the echocardiography la...

journal_title：European heart journal

authors： Picano E,Pellikka PA

更新日期：2014-04-01 00:00:00

abstract：AIMS:To investigate personality traits and sympatho-vagal modulation of heart rate variability (HRV) during acute myocardial infarction (AMI), assessing their relationships and their long-term prognostic value. METHODS AND RESULTS:Psychological traits and 24 h HRV were prospectively investigated in 246 patients at dis...

journal_title：European heart journal

authors： Carpeggiani C,Emdin M,Bonaguidi F,Landi P,Michelassi C,Trivella MG,Macerata A,L'Abbate A

更新日期：2005-08-01 00:00:00

abstract：AIMS:Habitual cigarette smokers, paradoxically, present improved short-term prognosis after acute myocardial infarction, a phenomenon often termed "smoker's paradox". We sought to examine cigarette smokers' post-infarction survival advantage in a countrywide survey of unselected, consecutive patients presenting with ac...

journal_title：European heart journal

authors： Andrikopoulos GK,Richter DJ,Dilaveris PE,Pipilis A,Zaharoulis A,Gialafos JE,Toutouzas PK,Chimonas ET

更新日期：2001-05-01 00:00:00

abstract：AIMS:The guidelines of the European Society of Cardiology (ESC) define the current standard for the management of syncope, but are still incompletely applied in the clinical setting. METHODS AND RESULTS:Prospective systematic evaluation, on strict adherence to the guidelines, of consecutive patients referred for synco...

journal_title：European heart journal

authors： Brignole M,Menozzi C,Bartoletti A,Giada F,Lagi A,Ungar A,Ponassi I,Mussi C,Maggi R,Re G,Furlan R,Rovelli G,Ponzi P,Scivales A

更新日期：2006-01-01 00:00:00

abstract：AIMS:To determine the prevalence, incidence rate, lifetime risk and prognosis of heart failure. METHODS AND RESULTS:The Rotterdam Study is a prospective population-based cohort study in 7983 participants aged > or =55. Heart failure was defined according to criteria of the European Society of Cardiology. Prevalence wa...

journal_title：European heart journal

authors： Bleumink GS,Knetsch AM,Sturkenboom MC,Straus SM,Hofman A,Deckers JW,Witteman JC,Stricker BH

更新日期：2004-09-01 00:00:00

abstract：AIMS:Subjects with lipoprotein(a) [Lp(a)] elevation have increased arterial wall inflammation and cardiovascular risk. In patients at increased cardiovascular risk, arterial wall inflammation is reduced following lipid-lowering therapy by statin treatment or lipoprotein apheresis. However, it is unknown whether lipid-l...

journal_title：European heart journal

authors： Stiekema LCA,Stroes ESG,Verweij SL,Kassahun H,Chen L,Wasserman SM,Sabatine MS,Mani V,Fayad ZA

更新日期：2019-09-01 00:00:00

abstract：AIMS:To explore variations in invasive care of the elderly with acute coronary syndromes across international practice. METHODS AND RESULTS:Using combined populations from the SYMPHONY and 2nd SYMPHONY trials, we describe 30-day cardiac catheterization in elderly (> or = 75 years; n = 1794) vs. younger patients (< 75 ...

journal_title：European heart journal

authors： Alexander KP,Newby LK,Bhapkar MV,White HD,Hochman JS,Pfisterer ME,Moliterno DJ,Peterson ED,Van de Werf F,Armstrong PW,Califf RM,Symphony and 2nd Symphony Investigators.

更新日期：2006-07-01 00:00:00

abstract：AIMS:Periconceptional folate supplementation prevents neural tube defects and possibly congenital heart defects (CHD) as well. The search for candidate genes involved in the folate metabolism includes the methylenetetrahydrofolate reductase (MTHFR) 677C > T polymorphism. We studied the association between MTHFR 677C > ...

journal_title：European heart journal

authors： van Beynum IM,Kapusta L,den Heijer M,Vermeulen SH,Kouwenberg M,Daniëls O,Blom HJ

更新日期：2006-04-01 00:00:00

abstract：AIMS:To determine what proportion of patients with heart failure are eligible for cardiac resynchronization therapy (CRT). METHODS AND RESULTS:Eligibility criteria from the trials establishing the efficacy of CRT were applied to two prospective cohorts: the first enrolled patients with newly diagnosed heart failure di...

journal_title：European heart journal

authors： McAlister FA,Tu JV,Newman A,Lee DS,Kimber S,Cujec B,Armstrong PW

更新日期：2006-02-01 00:00:00

abstract：AIMS:To quantify the prevalence of coronary artery calcification (CAC) in relation to cardiovascular risk factors in marathon runners, and to study its role for myocardial damage and coronary events. METHODS AND RESULTS:In 108 apparently healthy male marathon runners aged >or=50 years, with >or=5 marathon competitions...

journal_title：European heart journal

authors： Möhlenkamp S,Lehmann N,Breuckmann F,Bröcker-Preuss M,Nassenstein K,Halle M,Budde T,Mann K,Barkhausen J,Heusch G,Jöckel KH,Erbel R,Marathon Study Investigators.,Heinz Nixdorf Recall Study Investigators.

更新日期：2008-08-01 00:00:00

abstract：AIMS:We addressed a potential mechanism of myocardial dysfunction following coronary microembolization at the level of myofibrillar proteins. METHODS AND RESULTS:Anaesthetized pigs underwent intracoronary infusion of microspheres. After 6 h, the microembolized areas (MEA) had decreased systolic wall thickening to 38 +...

journal_title：European heart journal

authors： Canton M,Skyschally A,Menabò R,Boengler K,Gres P,Schulz R,Haude M,Erbel R,Di Lisa F,Heusch G

更新日期：2006-04-01 00:00:00

abstract：:Chronically ischaemic myocardium from patients with coronary heart disease was investigated by light and electron microscopy using tissue biopsies taken during cardiac surgery. Light microscopy showed a significantly increased amount of fibrotic material, cell size was variable. By electron microscopy, the most obviou...

journal_title：European heart journal

authors： Schaper J

更新日期：1988-01-01 00:00:00

abstract：AIMS:Chronic kidney disease (CKD) was found to be an independent risk factor for all-cause mortality as well as adverse cardiovascular disease (CVD) events in high-risk populations. Findings from population-based studies are scarce and inconsistent. We investigated the gender-specific association of CKD with all-cause ...

journal_title：European heart journal

authors： Meisinger C,Döring A,Löwel H,KORA Study Group.

更新日期：2006-05-01 00:00:00

abstract：AIMS:Patients with acute coronary syndrome (ACS) in the Myocardial Ischaemia Reduction with Aggressive Cholesterol Lowering (MIRACL) study had diminished cardiovascular events after 16 weeks of treatment of atorvastatin 80 mg daily. We determined whether plasma lipoproteins at baseline and then at 6 weeks after randomi...

journal_title：European heart journal

authors： Olsson AG,Schwartz GG,Szarek M,Sasiela WJ,Ezekowitz MD,Ganz P,Oliver MF,Waters D,Zeiher A

更新日期：2005-05-01 00:00:00

abstract：:Twenty-three patients who had undergone aortic valve replacement with a mechanical aortic valve prosthesis (ball-valve: 17, tilting-disc: 6) were investigated by retrograde left ventricular catheterization using a 6 F pigtail catheter. Twelve of these 23 patients also had had combined aortic and mitral valve replaceme...

journal_title：European heart journal

authors： Rigaud M,Dubourg O,Luwaert R,Rocha P,Hamoir V,Bardet J,Bourdarias JP

更新日期：1987-07-01 00:00:00

abstract：AIMS:The impact on mortality outcomes of beta-blockers and calcium blockers in post-myocardial infarction (MI) has been suggested to be related to resting heart rate (HR) reduction. A meta-regression of randomized clinical trials was carried out to assess this relationship using weighted meta-regression of logarithm of...

journal_title：European heart journal

authors： Cucherat M

更新日期：2007-12-01 00:00:00

abstract：:In 2008, The ESC Working Group on Myocardial and Pericardial Diseases proposed an updated classification of cardiomyopathies based on morphological and functional phenotypes and subcategories of familial/genetic and non-familial/non-genetic disease. In this position statement, we propose a framework for the clinical a...

journal_title：European heart journal

authors： Rapezzi C,Arbustini E,Caforio AL,Charron P,Gimeno-Blanes J,Heliö T,Linhart A,Mogensen J,Pinto Y,Ristic A,Seggewiss H,Sinagra G,Tavazzi L,Elliott PM

更新日期：2013-05-01 00:00:00

abstract：:I.S.A.M. was a prospective, placebo-controlled, double-blind multicentre trial of high-dose short-term intravenous streptokinase in acute myocardial infarction (AMI) within 6 h of the onset of symptoms. Determination of left ventricular ejection fraction (LVEF) by radionuclide ventriculography was performed 1 and 7 mo...

journal_title：European heart journal

authors： Voth E,Tebbe U,Schicha H,Neumann P,Schröder R,Neuhaus KL,Emrich D

更新日期：1990-10-01 00:00:00

abstract：:Thiazide diuretics are efficacious, either as monotherapy or in combination with other antihypertensive drugs. They reduce blood pressure in a high percentage of hypertensive patients with minimal subjective side effects. There is increasing evidence that the use of diuretics, singly or in combination, will reduce mor...

journal_title：European heart journal

authors： Moser M

更新日期：1992-12-01 00:00:00

abstract：AIMS:The long QT syndrome is mainly defined by QT interval prolongation (QTc > 0.44s). However, data obtained in genotyped patients showed that resting QTc measurement alone may be inaccurate for ascertaining the phenotype. The aim of this study was to evaluate the diagnostic performance of QT interval rate-dependence ...

journal_title：European heart journal

authors： Neyroud N,Maison-Blanche P,Denjoy I,Chevret S,Donger C,Dausse E,Fayn J,Badilini F,Menhabi N,Schwartz K,Guicheney P,Coumel P

更新日期：1998-01-01 00:00:00

abstract：:Spinal cord electrical stimulation is an alternative therapy for patients with chronic pain syndromes including angina. Although it has been shown to produce symptomatic relief and reduce ischaemia, doubts remain about its long-term safety. We report here for the first time the results of a follow-up study over a peri...

journal_title：European heart journal

authors： Sanderson JE,Ibrahim B,Waterhouse D,Palmer RB

更新日期：1994-06-01 00:00:00

abstract：:Although indicated by several experimental studies, the presence of a renin-angiotensin system has not been demonstrated in the human heart. The influence of a local renin-angiotensin system on the coronary vessels may be difficult to establish after oral or intravenous administration of an angiotensin converting-enzy...

journal_title：European heart journal

authors： Foult JM,Tavolaro O,Antony I,Nitenberg A

更新日期：1989-11-01 00:00:00

abstract：:Contraceptive counselling should begin early in females with heart disease, preferably directly after the start of menstruation. In coming to a decision about the method of contraception, the following issues should be considered: (i) the risk of pregnancy for the mother and the consequences of an unplanned pregnancy;...

journal_title：European heart journal

authors： Roos-Hesselink JW,Cornette J,Sliwa K,Pieper PG,Veldtman GR,Johnson MR

更新日期：2015-07-14 00:00:00

abstract：AIMS:This prospective, randomized, controlled, multicentre study aimed to evaluate efficacy and safety of exercise training in patients with pulmonary arterial (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). METHODS AND RESULTS:For the first time a specialized PAH/CTEPH rehabilitation programme was im...

journal_title：European heart journal

authors： Grünig E,MacKenzie A,Peacock AJ,Eichstaedt CA,Benjamin N,Nechwatal R,Ulrich S,Saxer S,Bussotti M,Sommaruga M,Ghio S,Gumbiene L,Palevičiūtė E,Jurevičienė E,Cittadini A,Stanziola AA,Marra AM,Kovacs G,Olschewski H,Barb

更新日期：2020-11-24 00:00:00

abstract：:The choice of oral anticoagulant (OAC) for patients with atrial fibrillation (AF) may be influenced by individual clinical features or by patterns of risk factors and comorbidities. We reviewed analyses of subgroups of patients from trials of vitamin K antagonists vs. non-vitamin K oral anticoagulants (NOACs) for stro...

journal_title：European heart journal

authors： Diener HC,Aisenberg J,Ansell J,Atar D,Breithardt G,Eikelboom J,Ezekowitz MD,Granger CB,Halperin JL,Hohnloser SH,Hylek EM,Kirchhof P,Lane DA,Verheugt FWA,Veltkamp R,Lip GYH

更新日期：2017-03-21 00:00:00

abstract：AIMS:Although a recent expert consensus statement has recommended periprocedural uninterrupted (UI) non-vitamin K antagonist oral anticoagulants (NOACs) during catheter ablation of atrial fibrillation (AF) as a Class I indication, there have been no clear randomized trials. We investigated the safety and efficacy of UI...

journal_title：European heart journal

authors： Yu HT,Shim J,Park J,Kim TH,Uhm JS,Kim JY,Joung B,Lee MH,Kim YH,Pak HN

更新日期：2019-05-14 00:00:00

abstract：AIMS:Calmodulinopathies are rare life-threatening arrhythmia syndromes which affect mostly young individuals and are, caused by mutations in any of the three genes (CALM 1-3) that encode identical calmodulin proteins. We established the International Calmodulinopathy Registry (ICalmR) to understand the natural history,...

journal_title：European heart journal

authors： Crotti L,Spazzolini C,Tester DJ,Ghidoni A,Baruteau AE,Beckmann BM,Behr ER,Bennett JS,Bezzina CR,Bhuiyan ZA,Celiker A,Cerrone M,Dagradi F,De Ferrari GM,Etheridge SP,Fatah M,Garcia-Pavia P,Al-Ghamdi S,Hamilton RM,Al-H

更新日期：2019-09-14 00:00:00

abstract：AIMS:Anaemia is often observed in patients with chronic heart failure (CHF), and it may be associated with a worse prognosis. Aim of this study was to identify the individual mechanisms of anaemia in CHF patients. METHODS AND RESULTS:One hundred and forty-eight consecutive patients with haemoglobin concentration <13 g...

journal_title：European heart journal

authors： Opasich C,Cazzola M,Scelsi L,De Feo S,Bosimini E,Lagioia R,Febo O,Ferrari R,Fucili A,Moratti R,Tramarin R,Tavazzi L

更新日期：2005-11-01 00:00:00