Performance of EuroSCORE in CABG and off-pump coronary artery bypass grafting: single institution experience and meta-analysis.


AIMS:To assess EuroSCORE performance in predicting in-hospital mortality in on-pump coronary artery bypass grafting (CABG) and off-pump coronary artery bypass grafting (OPCAB). METHODS AND RESULTS:Additive and logistic EuroSCORE were computed for consecutive patients undergoing CABG (n = 3440, 75%) or OPCAB (n = 1140, 25%) at our hospital from 1999 to September 2007. The areas under the receiver operating characteristic (ROC) curves (AUCs) were used to describe performance and accuracy. No difference in performance between CABG and OPCAB and between additive and logistic EuroSCORE (additive EuroSCORE AUCs of 0.808 and 0.779 for CABG and OPCAB, respectively; logistic EuroSCORE AUCs of 0.813 and of 0.773 for CABG and OPCAB, respectively) was found, although a marked tendency to overpredict mortality by both models was evident. A meta-analysis of previously published data was done, and a total of eight studies representing 19 212 and 5461 patients undergoing CABG and OPCAB, respectively, met inclusion criteria. Meta-analysis confirmed similar performance of EuroSCORE in CABG and OPCAB: estimated AUCs were 0.767 and 0.766 for CABG and OPCAB, respectively, with an estimated difference of 0.001 (95% CI -0.061 to 0.063). CONCLUSION:Additive and logistic EuroSCORE algorithms performed similarly, and cumulative evidence suggests comparable performance in CABG and OPCAB procedures; both risk models, however, significantly overestimated mortality.


Eur Heart J


European heart journal


Parolari A,Pesce LL,Trezzi M,Loardi C,Kassem S,Brambillasca C,Miguel B,Tremoli E,Biglioli P,Alamanni F




Has Abstract


2009-02-01 00:00:00














  • An autoantibody identifies arrhythmogenic right ventricular cardiomyopathy and participates in its pathogenesis.

    abstract:Aims:Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by right ventricular myocardial replacement and life-threatening ventricular arrhythmias. Desmosomal gene mutations are sometimes identified, but clinical and genetic diagnosis remains challenging. Desmosomal skin disorders can be caused by de...

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Chatterjee D,Fatah M,Akdis D,Spears DA,Koopmann TT,Mittal K,Rafiq MA,Cattanach BM,Zhao Q,Healey JS,Ackerman MJ,Bos JM,Sun Y,Maynes JT,Brunckhorst C,Medeiros-Domingo A,Duru F,Saguner AM,Hamilton RM

    更新日期:2018-11-21 00:00:00

  • Pretreatment with intracoronary adenosine reduces the incidence of myonecrosis after non-urgent percutaneous coronary intervention: a prospective randomized study.

    abstract:AIMS:We sought to investigate the effect of adenosine pretreatment on the incidence of myonecrosis after non-urgent percutaneous coronary intervention (PCI). METHODS AND RESULTS:This was a prospective, randomized, open-label study. Patients who were scheduled for non-urgent PCI in de novo native coronary arteries were...

    journal_title:European heart journal

    pub_type: 杂志文章,随机对照试验


    authors: Lee CH,Low A,Tai BC,Co M,Chan MY,Lim J,Lim YT,Tan HC

    更新日期:2007-01-01 00:00:00

  • Silent ischaemia in asymptomatic 'healthy' individuals with coronary risk factors.

    abstract::On the occasion of a routine medical check-up 256 out of 1100 individuals with an accumulation of coronary risk factors were screened for silent myocardial ischaemia by exercise testing and Holter monitoring. Of these individuals 5.5% had a pathological exercise test, 7.4% had ischaemia-like events on the Holter ECG, ...

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Osterspey A,Treis-Müller I,Günther H,Eggeling T,Siglow C,Gedicke V,Höpp H,Diewitz M,Osterhues H,Hilger HH

    更新日期:1988-12-01 00:00:00

  • Running: the risk of coronary events : Prevalence and prognostic relevance of coronary atherosclerosis in marathon runners.

    abstract:AIMS:To quantify the prevalence of coronary artery calcification (CAC) in relation to cardiovascular risk factors in marathon runners, and to study its role for myocardial damage and coronary events. METHODS AND RESULTS:In 108 apparently healthy male marathon runners aged >or=50 years, with >or=5 marathon competitions...

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Möhlenkamp S,Lehmann N,Breuckmann F,Bröcker-Preuss M,Nassenstein K,Halle M,Budde T,Mann K,Barkhausen J,Heusch G,Jöckel KH,Erbel R,Marathon Study Investigators.,Heinz Nixdorf Recall Study Investigators.

    更新日期:2008-08-01 00:00:00

  • Impact of glucose-lowering drugs on cardiovascular disease in type 2 diabetes.

    abstract::Type 2 diabetes mellitus (T2DM) is characterized by multiple pathophysiologic abnormalities. With time, multiple glucose-lowering medications are commonly required to reduce and maintain plasma glucose concentrations within the normal range. Type 2 diabetes mellitus individuals also are at a very high risk for microva...

    journal_title:European heart journal

    pub_type: 杂志文章,评审


    authors: Ferrannini E,DeFronzo RA

    更新日期:2015-09-07 00:00:00

  • Progress in the diagnosis of unstable angina and perspectives for treatment.

    abstract::Unstable angina is a high-risk phase of coronary heart disease defined by clinical symptoms. Electrocardiographic findings are heterogeneous and creatine kinase is only rarely elevated. However, troponin T and troponin I are found in about 30-40% of patients with angina at rest disclosing minor myocardial cell injury....

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Hamm CW

    更新日期:1998-11-01 00:00:00

  • N-terminal brain natriuretic peptide as a screening tool for heart failure in the pacemaker population.

    abstract:AIMS:Assessment of N-terminal brain natriuretic peptide (NT-BNP) as a screening tool for heart failure in patients with a permanent pacemaker. METHODS AND RESULTS:Consecutive patients undergoing a routine permanent pacemaker assessment were enrolled. Patients underwent medical history and examination, echocardiography...

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Thackray SD,Witte K,Ghosh J,Nikitin N,Anderson A,Rigby A,Goode K,Clark AL,Cleland JG

    更新日期:2006-02-01 00:00:00

  • Identification of pacemaker dependent patients by serial decremental rate inhibition.

    abstract::In a study of the concept of pacemaker dependence, 86 patients who had permanent ventricular demand (VVI) pacemakers implanted for more than six months and were in predominantly paced rhythm underwent repeated interruption of pacing both abruptly and after gradual reduction of paced rate. Non-invasive pace slowing was...

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Crick JC,Rokas S,Sowton E

    更新日期:1985-10-01 00:00:00

  • Cost-effectiveness of an invasive strategy in unstable coronary artery disease; results from the FRISC II invasive trial. The Fast Revascularisation during InStability in Coronary artery disease.

    abstract:AIMS:The utilization and timing of revascularization in unstable coronary artery disease varies, which could have important consequences for patients and for treatment costs. The FRISC II invasive trial compared an early invasive strategy vs a non-invasive strategy with respect to the composite end-point of death and m...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Janzon M,Levin LA,Swahn E

    更新日期:2002-01-01 00:00:00

  • A common variant in CCDC93 protects against myocardial infarction and cardiovascular mortality by regulating endosomal trafficking of low-density lipoprotein receptor.

    abstract:AIMS:Genome-wide association studies have previously identified INSIG2 as a candidate gene for plasma low-density lipoprotein cholesterol (LDL-c). However, we suspect a role for CCDC93 in the same locus because of its involvement in the recycling of the LDL-receptor (LDLR). METHODS AND RESULTS:Characterization of the ...

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Rimbert A,Dalila N,Wolters JC,Huijkman N,Smit M,Kloosterhuis N,Riemsma M,van der Veen Y,Singla A,van Dijk F,Biobank-Based Integrative Omics Studies Consortium.,Frikke-Schmidt R,Burstein E,Tybjærg-Hansen A,van de Sluis B,Kui

    更新日期:2020-03-01 00:00:00

  • Extension of native aortic valve endocarditis: surgical considerations.

    abstract::Among 101 consecutive patients operated on for native infective aortic valve endocarditis (53 males, 48 females, mean age 39 years), 69 presented various forms of infectious extension to the surrounding areas. Twenty-six lesions were noted in the aortic roots: 18 annular abscesses, one abscess of the Valsalva sinus an...

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Amrani M,Schoevaerdts JC,Eucher P,Nicolas AL,Dion R,Kremer R

    更新日期:1995-04-01 00:00:00

  • European Society of Cardiology: Cardiovascular Disease Statistics 2019.

    abstract:AIMS:The 2019 report from the European Society of Cardiology (ESC) Atlas provides a contemporary analysis of cardiovascular disease (CVD) statistics across 56 member countries, with particular emphasis on international inequalities in disease burden and healthcare delivery together with estimates of progress towards me...

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Timmis A,Townsend N,Gale CP,Torbica A,Lettino M,Petersen SE,Mossialos EA,Maggioni AP,Kazakiewicz D,May HT,De Smedt D,Flather M,Zuhlke L,Beltrame JF,Huculeci R,Tavazzi L,Hindricks G,Bax J,Casadei B,Achenbach S,Wrig

    更新日期:2020-01-01 00:00:00

  • Effect of revascularizing viable myocardium on left ventricular diastolic function in patients with ischaemic cardiomyopathy.

    abstract:AIMS:In patients with ischaemic left ventricular (LV) dysfunction and viable myocardium, revascularization improves systolic function. Diastolic dysfunction is also present in such patients; however, whether revascularization improves diastolic function also is largely unknown. METHODS:Twenty-six patients with chronic...

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Carluccio E,Biagioli P,Alunni G,Murrone A,Leonelli V,Pantano P,Vincenti G,Giombolini C,Ragni T,Reboldi G,Gentile F,Ambrosio G

    更新日期:2009-06-01 00:00:00

  • Exercise and the heart: the good, the bad, and the ugly.

    abstract::The benefits of exercise are irrefutable. Individuals engaging in regular exercise have a favourable cardiovascular risk profile for coronary artery disease and reduce their risk of myocardial infarction by 50%. Exercise promotes longevity of life, reduces the risk of some malignancies, retards the onset of dementia, ...

    journal_title:European heart journal

    pub_type: 杂志文章,评审


    authors: Sharma S,Merghani A,Mont L

    更新日期:2015-06-14 00:00:00

  • Diabetes clinical trials: helped or hindered by the current shift in regulatory requirements?

    abstract::Glycaemic control is an inadequate surrogate marker of cardiovascular event reduction in patients with type 2 diabetes. Clinical trials to date have been unsuccessful in identifying a therapeutic approach that addresses the underlying problem in diabetes (glycaemic control) and reduces cardiovascular risk. The potenti...

    journal_title:European heart journal

    pub_type: 杂志文章,评审


    authors: Zannad F,Stough WG,Pocock SJ,Sleight P,Cushman WC,Cleland JG,McMurray JJ,Lonn E,Geller NL,Wedel H,Abadie E,Alonso-Garcia A,Pitt B

    更新日期:2012-05-01 00:00:00

  • Triglycerides, a major coronary risk factor in elderly men. A study of men born in 1913.

    abstract::We examined two 'cohorts' of elderly men, 60 and 67 years old. The two 'cohorts' overlapped to a large extent in terms of numbers but not in the follow-up periods. The mean have been followed-up for 7 and 8 years respectively. Among the 748 60-year-old men without prior myocardial infarction the 7-year incidence of co...

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Welin L,Eriksson H,Larsson B,Ohlson LO,Svärdsudd K,Tibblin G,Wilhelmsen L

    更新日期:1991-06-01 00:00:00

  • Exercise testing of healthy men in a new perspective: from diagnosis to prognosis.

    abstract:AIM:It has recently been suggested that exercise testing may be more valuable prognostically than it is diagnostically in apparently healthy subjects. We wanted to compare the accuracy of CHD risk assessment based on classical risk factors with an assessment also based on multiple exercise test parameters. METHODS AND...

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Erikssen G,Bodegard J,Bjørnholt JV,Liestøl K,Thelle DS,Erikssen J

    更新日期:2004-06-01 00:00:00

  • Arginase I enhances atherosclerotic plaque stabilization by inhibiting inflammation and promoting smooth muscle cell proliferation.

    abstract:AIMS:The aim of this study was to investigate the effect of Arginase I (ArgI) on plaque stabilization in unruptured atherosclerotic plaque and explore its mechanism. METHODS AND RESULTS:The atherosclerotic plaque model was established in New Zealand rabbits by balloon injury of abdominal arteries and a high cholestero...

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Wang XP,Zhang W,Liu XQ,Wang WK,Yan F,Dong WQ,Zhang Y,Zhang MX

    更新日期:2014-04-01 00:00:00

  • Management of the patient with left ventricular hypertrophy.

    abstract::The management of left ventricular hypertrophy (LVH) presupposes that the patient is identified by echocardiography and is carefully evaluated for risk stratification, taking into consideration possible associated complications. The role of non-pharmacological treatment is limited, except in obese patients. Drug treat...

    journal_title:European heart journal

    pub_type: 杂志文章,评审


    authors: de Divitiis O,Celentano A,De Simone G,Di Somma S,Galderisi M,Liguori V,de Divitiis M,Petitto M

    更新日期:1993-07-01 00:00:00

  • Acute rise of circulating vascular endothelial growth factor-A in patients with coronary artery disease following cardiothoracic surgery.

    abstract:AIMS:Vascular endothelial growth factor-A (VEGF-A) is an angiogenic and vasoprotective molecule whose expression is modulated by hypoxia and inflammatory mediators. Here we have tested the hypothesis that plasma levels of VEGF-A are influenced by pre-existing coronary artery disease and by changes in circulating interl...

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Cotton JM,Mathur A,Hong Y,Brown AS,Martin JF,Erusalimsky JD

    更新日期:2002-06-01 00:00:00

  • Effects of diuretics on renal excretory function.

    abstract::From a clinicopharmacological standpoint, the urinary excretory potency of diuretics should be assessed comparatively, on the basis of placebo-controlled changes in 24 h natriuresis, following single oral doses administered to healthy adult subjects who are in steady-state habitual external sodium balance. The potency...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Reyes AJ

    更新日期:1992-12-01 00:00:00

  • Alirocumab in patients with heterozygous familial hypercholesterolaemia undergoing lipoprotein apheresis: the ODYSSEY ESCAPE trial.

    abstract:AIM:To evaluate the effect of alirocumab on frequency of standard apheresis treatments [weekly or every 2 weeks (Q2W)] in heterozygous familial hypercholesterolaemia (HeFH). METHODS AND RESULTS:ODYSSEY ESCAPE (NCT02326220) was a double-blind study in 62 HeFH patients undergoing regular weekly or Q2W lipoprotein aphere...

    journal_title:European heart journal

    pub_type: 杂志文章,随机对照试验


    authors: Moriarty PM,Parhofer KG,Babirak SP,Cornier MA,Duell PB,Hohenstein B,Leebmann J,Ramlow W,Schettler V,Simha V,Steinhagen-Thiessen E,Thompson PD,Vogt A,von Stritzky B,Du Y,Manvelian G

    更新日期:2016-12-21 00:00:00

  • The 60 minutes myocardial infarction project. Treatment and clinical outcome of patients with acute myocardial infarction in Germany.

    abstract:AIMS:To describe patient characteristics, pre-hospital delay, treatment, complications and outcome in patients with acute myocardial infarction admitted to hospitals in Germany. METHODS AND RESULTS:The study was of prospective observational multicentre design. Those involved were consecutive patients with acute Q-wave...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究


    authors: Rustige J,Schiele R,Burczyk U,Koch A,Gottwik M,Neuhaus KL,Tebbe U,Uebis R,Senges J

    更新日期:1997-09-01 00:00:00

  • Creatine kinase-MB elevation after percutaneous coronary intervention predicts adverse outcomes in patients with acute coronary syndromes.

    abstract:AIM:To study the relationship between outcomes and peak creatine kinase (CK)-MB levels after percutaneous coronary intervention (PCI) in patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS). METHODS AND RESULTS:Peak CK-MB ratios (peak CK-MB level/upper limit of normal [ULN]) after PCI were analys...

    journal_title:European heart journal

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Roe MT,Mahaffey KW,Kilaru R,Alexander JH,Akkerhuis KM,Simoons ML,Harrington RA,Tardiff BE,Granger CB,Ohman EM,Moliterno DJ,Lincoff AM,Armstrong PW,Van de Werf F,Califf RM,Topol EJ

    更新日期:2004-02-01 00:00:00

  • Impaired myocardial perfusion reserve and fibrosis in Friedreich ataxia: a mitochondrial cardiomyopathy with metabolic syndrome.

    abstract:AIMS:Cardiomyopathy produces significant mortality in patients with Friedreich ataxia (FA), a genetic disorder that produces intra-mitochondrial iron accumulation. We sought to test the hypothesis that abnormal myocardial perfusion reserve and fibrosis represent early manifestations of cardiomyopathy. METHODS AND RESU...

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Raman SV,Phatak K,Hoyle JC,Pennell ML,McCarthy B,Tran T,Prior TW,Olesik JW,Lutton A,Rankin C,Kissel JT,Al-Dahhak R

    更新日期:2011-03-01 00:00:00

  • International Expert Consensus Document on Takotsubo Syndrome (Part II): Diagnostic Workup, Outcome, and Management.

    abstract::The clinical expert consensus statement on takotsubo syndrome (TTS) part II focuses on the diagnostic workup, outcome, and management. The recommendations are based on interpretation of the limited clinical trial data currently available and experience of international TTS experts. It summarizes the diagnostic approac...

    journal_title:European heart journal

    pub_type: 共识发展会议,杂志文章


    authors: Ghadri JR,Wittstein IS,Prasad A,Sharkey S,Dote K,Akashi YJ,Cammann VL,Crea F,Galiuto L,Desmet W,Yoshida T,Manfredini R,Eitel I,Kosuge M,Nef HM,Deshmukh A,Lerman A,Bossone E,Citro R,Ueyama T,Corrado D,Kurisu S,

    更新日期:2018-06-07 00:00:00

  • Deficiency of type 1 cannabinoid receptors worsens acute heart failure induced by pressure overload in mice.

    abstract:AIMS:We investigated the influence of type one cannabinoid receptor (CB1) deficiency on acute heart failure (AHF) and the underlying mechanism. Acute heart failure syndrome is an important clinical problem because of its high morbidity and mortality rates. Activation of CB1 induces vascular dilation and reinforces the ...

    journal_title:European heart journal

    pub_type: 杂志文章


    authors: Liao Y,Bin J,Asakura M,Xuan W,Chen B,Huang Q,Xu D,Ledent C,Takashima S,Kitakaze M

    更新日期:2012-12-01 00:00:00

  • Innovations in imaging for chronic total occlusions: a glimpse into the future of angiography's blind-spot.

    abstract::Chronic total occlusions (CTOs) are a subset of lesions that present a considerable burden to cardiovascular patients. There exists a strong clinical desire to improve non-surgical options for CTO revascularization. While several techniques, devices, and guide wires have been developed and refined for use in CTOs, the...

    journal_title:European heart journal

    pub_type: 杂志文章,评审


    authors: Courtney BK,Munce NR,Anderson KJ,Thind AS,Leung G,Radau PE,Foster FS,Vitkin IA,Schwartz RS,Dick AJ,Wright GA,Strauss BH

    更新日期:2008-03-01 00:00:00

  • Efficacy of ivabradine, a new selective I(f) inhibitor, compared with atenolol in patients with chronic stable angina.

    abstract:AIMS:Ivabradine, a new I(f) inhibitor which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent. Ivabradine has shown anti-ischaemic and anti-anginal activity in a placebo-controlled trial. The objective of this study was to compare the anti-anginal and anti-ischaemic...

    journal_title:European heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Tardif JC,Ford I,Tendera M,Bourassa MG,Fox K,INITIATIVE Investigators.

    更新日期:2005-12-01 00:00:00

  • Mitral valve repair for mitral insufficiency.

    abstract::Degenerative mitral valve disease has become the major cause of mitral regurgitation in North America; it is incumbent on surgeons to know repair techniques and to document their results. Fortunately, improvements in myocardial protection have been concurrent with the evolution of mitral valve repair in our country. T...

    journal_title:European heart journal

    pub_type: 杂志文章,评审


    authors: Loop FD,Cosgrove DM,Stewart WJ

    更新日期:1991-07-01 00:00:00