Analysis of dendritic cell trafficking using EGFP-transgenic mice.

abstract：:Although there is growing evidence that NKT cells play an important role in various immune responses through the invariant T cell receptor, other cell surface molecules responsible for their function are not fully understood. Here we study the role of ICOS, the third member of the CD28 family of costimulatory receptor...

journal_title：Immunology letters

authors： Watanabe S,Ohnuki K,Hara Y,Ishida Y,Ikarashi Y,Ogawa S,Kishimoto H,Tanabe K,Abe R

更新日期：2010-01-18 00:00:00

abstract：:The earliest T-cell precursor population in the adult mouse thymus (low CD4 precursors) may be divided into 85% of cells expressing surface Mel-14 (LECAM-1, the lymphocyte homing receptor) and 15% of cells which are Mel-14. To date, this is the only surface marker for which we have found this population to be heteroge...

journal_title：Immunology letters

authors： Wu L,D'Amico A

更新日期：1994-05-01 00:00:00

abstract：:Serum obtained from mice infected with Trypanosoma cruzi have antibodies able to induce immune lysis in presence of complement. Gel filtration in Sephadex G-200 and affinity chromatography with rabbit anti-mouse IgG and protein A-Sepharose showed that the antibodies responsible for the immune serum lytic activity are ...

journal_title：Immunology letters

authors： Stefani MM,Takehara HA,Mota I

更新日期：1983-01-01 00:00:00

abstract：:We have previously reported that the capacity of highly malignant B16BL6 murine melanoma cells to induce cell death in naive syngeneic lymphocytes stems from the absence of major histocompatibility complex (MHC) class I glycoproteins in these melanoma cells. Our present study provides evidence that the above-mentioned...

journal_title：Immunology letters

authors： Kellman-Pressman S,Fishman D,Tsory S,Segal S

更新日期：2005-09-15 00:00:00

abstract：:Human natural killer (NK) cell activity was not significantly affected by leukotriene (LT) B4 over a wide concentration range (10(-6)-10(-14) M), whether added directly to the NK cell assay or after preincubation of effector cells for 2 h with the drug before addition of Cr labelled K562 target cells. In addition, LTB...

journal_title：Immunology letters

authors： Hall TJ,Brostoff J

更新日期：1985-01-01 00:00:00

abstract：:We have investigated the cellular responses of guinea-pig macrophages to human C4a. C4a induced a biphasic Ca2+ mobilization; a rapid temporary Ca2+ mobilization from intracellular Ca2+ pool followed by a weak Ca2+ influx of extracellular Ca2+. Although the C4a-treated macrophages did not respond again to C4a, that is...

journal_title：Immunology letters

authors： Murakami Y,Yamamoto T,Imamichi T,Nagasawa S

更新日期：1993-06-01 00:00:00

abstract：:Whilst many physiological functions of nitric oxide (NO) have been revealed so far, recent evidence proposes an essential role for NO in T lymphocyte activation and signal transduction. NO acts as a second messenger, activating soluble guanyl cyclase and participating in signal transduction pathways involving cyclic G...

journal_title：Immunology letters

authors： Nagy G,Clark JM,Buzás EI,Gorman CL,Cope AP

更新日期：2007-07-31 00:00:00

abstract：:Recombinant gp120 of the HIV-1(IIIB) isolate (BH10 clone) has been mutated to form the PR12 protein with the first 74 C-terminal amino acids and the V1, V2 and V3 hypervariable loops deleted. A variety of studies have shown that the CD4 binding domain (CD4bd) is very well exposed in PR12 in contrast to rgp120(LAI). Us...

journal_title：Immunology letters

authors： Jeffs SA,Gorny MK,Williams C,Revesz K,Volsky B,Burda S,Wang XH,Bandres J,Zolla-Pazner S,Holmes H

更新日期：2001-12-03 00:00:00

abstract：:When IL-4 mRNA was distinguished from mRNA encoding its antagonist, the splice variant IL-4delta2, it was found to correlate directly with expression of TLR2 in fresh peripheral blood mononuclear cells (PBMCs) from normal donors (p=0.0013). Similarly IL-4 mRNA was high when TLR2 mRNA was abundant compared to levels of...

journal_title：Immunology letters

authors： Chang JS,Dheda K,Huggett JF,Kim LU,Zumla A,Rook GA

更新日期：2006-08-15 00:00:00

abstract：:Work on mast cells and basophils began with their identification by Paul Ehrlich at the end of the 19th century. Mast cells and basophils were immediately perceived as closely linked cells and early nomenclature formulated by Ehrlich himself, i.e., tissue "Mastzellen" and blood "Mastzellen", reflected this unifying vi...

journal_title：Immunology letters

authors： Crivellato E,Nico B,Ribatti D

更新日期：2011-12-30 00:00:00

abstract：:Alpha-fetoprotein (AFP), an onco-fetal protein which binds specifically polyunsaturated fatty acids, has been shown to modulate arachidonic acid metabolism in a human T-cell line. In Jurkat lymphoma cells, AFP decreases the synthesis of prostaglandins and increases the release of arachidonic acid and leukotrienes. The...

journal_title：Immunology letters

authors： Aussel C,Fehlmann M

更新日期：1987-01-01 00:00:00

abstract：:We have studied the autocrine regulation of essential expression of the intercellular adhesion molecule-1 (ICAM-1) on 8 transitional cell carcinoma (TCC) cell lines (histopathological grades 1-3). The constitutive expression of ICAM-1 was regulated by soluble factors in an autocrine fashion. These factors were produce...

journal_title：Immunology letters

authors： Alexandroff AB,Jackson AM,Esuvaranathan K,Prescott S,James K

更新日期：1994-05-01 00:00:00

abstract：:Aging is associated to dysfunctional changes in the immune system, a process termed immunosenescence. Elderly individuals usually present chronic low level inflammation, likely as the consequence of continued exposure to antigens combined with poor immune function, increases in production of pro-inflammatory cytokines...

journal_title：Immunology letters

authors： Campos C,Pera A,Lopez-Fernandez I,Alonso C,Tarazona R,Solana R

更新日期：2014-11-01 00:00:00

abstract：:A considerable body of evidence from various laboratories indicates that specific T cell responses generated during infection with Leishmania parasites play an important role both in the resolution and progression of cutaneous leishmaniasis. Recent data, summarized in this article, indicate that resolution of lesions ...

journal_title：Immunology letters

authors： Müller I,Pedrazzini T,Louis JA

更新日期：1988-11-01 00:00:00

abstract：:There has been significant progress in the field of heart transplantation over the last 45 years. Although the role of adaptive immunity in heart allograft rejection has been extensively studied for decades, there is increasing evidence that suggests that the innate immune system also contributes to the development of...

journal_title：Immunology letters

authors： Lv Q,Li C,Mo Y,He L

更新日期：2018-02-01 00:00:00

abstract：:Soluble C3d applied to human blood-derived B lymphocytes inhibited anti-mu, T cell-produced growth factor, and EBV-induced DNA synthesis in serum-free culture. C3d added to the B cell cultures 1 and 2 days after the stimulus, still exerted inhibition, though with gradually diminishing efficiency. C3d, fixed on zymosan...

journal_title：Immunology letters

authors： Kuraya M,Nilsson B,Nilsson-Ekdahl K,Klein E

更新日期：1990-10-01 00:00:00

abstract：:Mouse trisomy 16 (Ts16), an animal model for human Down syndrome (trisomy 21), exhibits severe abnormalities in the development of lymphoid and myeloid cells. Whereas fetal liver cells from diploid mice can be easily immortalized by retroviral transformation with Ab1-MuLV or J2 virus, fetal livers from Ts16 mice conta...

journal_title：Immunology letters

authors： Berger CN,Epstein CJ

更新日期：1992-06-01 00:00:00

abstract：:Mimotopes derived from peptide phage display libraries may reproduce basic functions of epitopes including their antigenicity. In case of toxins, this property makes phage displayed mimotopes highly specific vaccine components free of the toxicity. To explore the potential of mimotopes for vaccine development, their a...

journal_title：Immunology letters

authors： Hernández R,Gazarian TG,Hérion PS,Gazarian KG

更新日期：2002-02-01 00:00:00

abstract：:It is well known that most physiological functions change with aging, including the immune response. Data concerning the aging of lymphocyte subpopulations are conflicting. The antigen density of peripheral blood lymphocytes has been determined by fluorescently tagged OKT-3, OKT-4, OKT-8, OKT-11 and OKM1 monoclonal an...

journal_title：Immunology letters

authors： Varga Z,Bressani N,Zaia AM,Bene L,Fülöp T,Leövey A,Fabris N,Damjanovich S

更新日期：1990-02-01 00:00:00

abstract：:Two chicken monoclonal antibodies (MAbs), HU/Ch2-7 and HU/Ch6-1, against heterophil Hanganutziu-Deicher (HD) antigens with N-glycolylneuraminic acid (NeuGc) at a terminal carbohydrate were established by cell fusions using chicken B cell lines lacking thymidine kinase and spleen cells from chickens immunized with II3N...

journal_title：Immunology letters

authors： Asaoka H,Nishinaka S,Wakamiya N,Matsuda H,Murata M

更新日期：1992-03-01 00:00:00

abstract：:This article has been withdrawn at the request of the editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal. ...

journal_title：Immunology letters

authors： Karimabad MN,Falahati-Pour SK,Hassanshahi G,Koochakzadeh L

更新日期：2017-08-26 00:00:00

abstract：:Differentiation between a non-infective and an infective Leishmania promastigote population was demonstrated. Promastigotes in the stationary phase (day 5) were found to be highly infective in vitro to BALB/c mouse peritoneal macrophages, compared with those of the logarithmic phase (day 3). The infective promastigote...

journal_title：Immunology letters

authors： Rizvi FS,Afchain D,Sherlock I,Sadigursky M,Capron A,Santoro F

更新日期：1985-01-01 00:00:00

abstract：:Monoclonal antibodies of the Orthoclone series were used to identify total T lymphocytes (OKT3) and their helper-inducer (OKT4) and cytotoxic-suppressor (OKT8) subsets in 25 patients with chronic Chagas' disease and 25 healthy controls. No significant difference in the number of total T cells (OKT3+) circulating in th...

journal_title：Immunology letters

authors： Gattass CR,Albanesi Fo FM,Barcinski MA

更新日期：1984-01-01 00:00:00

abstract：:We examined the alphabeta T cell receptor (TCR) repertoire of naturally occurring CD4+CD25+ regulatory T (Treg) cells isolated from healthy human blood. Three-color FACS analysis demonstrated that the usage of variable region segments of TCRbeta chains by CD4+CD25+ cells did not differ from those of CD4+CD25- cells. C...

journal_title：Immunology letters

authors： Fujishima M,Hirokawa M,Fujishima N,Sawada K

更新日期：2005-07-15 00:00:00

abstract：:Between the ages of 2 to approximately 11 days mice respond to a challenge with syngeneic IgE by producing anti-IgE antibodies; by the age of 2 weeks they are unresponsive. Even adult mice, however, produce high titers of anti-IgE antibodies when immunized with a conjugate of syngeneic IgE and a foreign antigen such a...

journal_title：Immunology letters

authors： Haba S,Nisonoff A

更新日期：1995-09-01 00:00:00

abstract：:Cultured T lymphocytes from pig blood can be activated by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA). Activation is additive with that induced by the mitogenic lectin phytohaemagglutinin (PHA). Activation by TPA differs from that induced by PHA or other mitogenic lectins in that it is not inhibited e...

journal_title：Immunology letters

authors： Kay JE,Meehan RT,Benzie CR

更新日期：1983-01-01 00:00:00

abstract：:Using micro-electrode technique we studied the effects of interleukin-2 (50 ng/ml) on bio-electric activity of rat atrial myocardium under normal conditions and after gradual stretching of the tissue. It was shown that interleukin-2 caused increasing in the duration of action potential at the levels of 25, 50, and 90%...

journal_title：Immunology letters

authors： Aksyonov A,Mitrokhin VM,Mladenov MI

更新日期：2015-09-01 00:00:00

abstract：:Control animals and rats infected 90 days earlier, by inoculation of 1 x 10(6) trypomastigotes of Trypanosoma cruzi at weaning, were subjected to adult thymectomy (ATx) or sham operation (S-ATx) and assessed 3 months later for the presence of myocardial lesions and levels of lymph node and spleen T-cell populations. C...

journal_title：Immunology letters

authors： Bottasso OA,Revelli SS,Dávila H,Valenti JL,Musso OC,Ferro ME,Romero-Piffiguer M,Morini JC

更新日期：1993-08-01 00:00:00

abstract：:Interleukin-18 (IL-18) gene promoter polymorphism is known as a genetic risk factor for child type 1 diabetes mellitus development. To test the role of IL-18 gene polymorphism in predisposition to adult type 1 diabetes (T1DM) and latent autoimmune diabetes in adults (LADA), we analysed SNPs at position -607 (C/A) and ...

journal_title：Immunology letters

authors： Novota P,Kolostova K,Pinterova D,Novak J,Treslova L,Andel M,Cerna M

更新日期：2005-01-31 00:00:00

abstract：:Transplantation immunologists have long been intrigued by the natural allograft that results from normal mammalian pregnancy. Its general success contrasts with the rejection problems associated with most artifactual organ transplantation and raises intriguing questions concerning the nature of the mechanisms involved...

journal_title：Immunology letters

authors： Wegmann TG

更新日期：1988-04-01 00:00:00