Correlates of immunity for pneumococcal conjugate vaccines.

abstract：:The aim of the study was to compare the responses of homosexual men (HM) receiving a standard course of recombinant hepatitis B vaccine with those of healthcare workers vaccinated in the same hospital over the same period. Boosters for inadequate responders and repeat courses for non-responders were given. Forty of 61...

journal_title：Vaccine

authors： Das S,Brassington M,Drake SM,Boxall E

更新日期：2003-09-08 00:00:00

abstract：:The authors trace the origins and history of anthrax and anthrax vaccines. They describe the aetiology and pathogenesis of the disease and the variety of symptoms which result from infection. The authors relate the early work performed by Pasteur, the development of existing vaccines and the efficacy of these vaccines...

journal_title：Vaccine

authors： Hambleton P,Carman JA,Melling J

更新日期：1984-06-01 00:00:00

abstract：:An ideal prophylactic human papillomavirus (HPV) vaccine would provide broadly protective and long-lasting immune responses against all high-risk HPV types, would be effective after a single dose, and would be formulated in such a manner to allow for long-term storage without the necessity for refrigeration. We have d...

journal_title：Vaccine

authors： Tumban E,Muttil P,Escobar CA,Peabody J,Wafula D,Peabody DS,Chackerian B

更新日期：2015-06-26 00:00:00

abstract：:Vaccines against group B meningococcal infection tested in several field trials have all been extracts of the outer membrane of the bacteria. We have developed a single component vaccine based on the class 1 outer membrane protein P1 produced in a heterologous host Bacillus subtilis, and describe here its immunizing p...

journal_title：Vaccine

authors： Idänpään-Heikkilä I,Wahlström E,Muttilainen S,Nurminen M,Käyhty H,Sarvas M,Mäkelä PH

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVES:To assess immunogenicity and safety of the 23-valent polysaccharide pneumococcal vaccine (PPV23) in juvenile idiopathic arthritis (JIA) patients under conventional DMARDs with or without anti-TNF therapy. The influences of demographic data, disease activity and treatment on immune response and the potential ...

journal_title：Vaccine

authors： Aikawa NE,França IL,Ribeiro AC,Sallum AM,Bonfa E,Silva CA

更新日期：2015-01-29 00:00:00

abstract：:Only viruses of the Influenzavirus A genus have been isolated from birds and termed avian influenza [AI] viruses, but viruses with all 16 haemagglutinin [H1-H16] and all 9 neuraminidase [N1-N9] influenza A subtypes in the majority of possible combinations have been isolated from avian species. Influenza A viruses infe...

journal_title：Vaccine

authors： Alexander DJ

更新日期：2007-07-26 00:00:00

abstract：:Despite extensive research, no unifying concept has satisfactorily explained the cause of the sudden infant death syndrome (SIDS). The details are briefly outlined of some of the evidence supporting the hypothesis that common bacterial toxins are important in the aetiology of SIDS. These bacterial toxins act as trigge...

journal_title：Vaccine

authors： Murrell TG,Murrell WG,Lindsay JA

更新日期：1994-03-01 00:00:00

abstract：:Recombinant canarypox (CP) and fowlpox (FP) viruses that contained two forms of the HIV-1 (SF2 strain) env gene were engineered and their expression analysed in chick, simian and human cells. These vectors can efficiently replicate in avian but not in mammalian cells, in which infection is abortive. The two forms, con...

journal_title：Vaccine

authors： Radaelli A,De Giuli Morghen C

更新日期：1994-09-01 00:00:00

abstract：AIMS:The study was designed to evaluate a novel cationic lipid DNA adjuvant (N3) and its function for HIV-1gp160/rev DNA plasmid delivered intranasally. The primary N3/HIV-DNA plasmid immunizations were boosted intranasally with a gp41 peptide in a anionic L3 adjuvant. This novel prime-boost strategy of mucosal immuniz...

journal_title：Vaccine

authors： Hinkula J,Devito C,Zuber B,Benthin R,Ferreira D,Wahren B,Schröder U

更新日期：2006-05-22 00:00:00

abstract：:Previously, we showed that vaccination with the glycoprotein D (gD) gene of pseudorabies virus (PrV) delivered by Escherichia coli induced protective immune responses. In this study, we report that oral DNA vaccination with attenuated Salmonella choleraesuis carrying the PrV gD gene conferred protective immunity in mi...

journal_title：Vaccine

authors： Shiau AL,Chen YL,Liao CY,Huang YS,Wu CL

更新日期：2001-07-16 00:00:00

abstract：:Rams which were vaccinated at 6-8 months of age with a water-in-oil Brucella ovis-vitamin E adjuvant vaccine had significantly higher serum antibody levels than rams vaccinated with a commercial B. ovis bacterin or B. melitensis Rev 1. The adjuvant vaccine did not cause abscesses at the site of injection as some water...

journal_title：Vaccine

authors： Tengerdy RP,Ameghino E,Riemann H

更新日期：1991-04-01 00:00:00

abstract：:The aim of the study was to investigate factors involved in vaccination acceptance among healthcare workers (HCWs) and adverse reactions rates associated with pandemic influenza vaccination. The study was carried out in the major teaching hospital of Sicily from November 2009 to February 2010 on 2267 HCWs. A total of ...

journal_title：Vaccine

authors： Amodio E,Anastasi G,Marsala MG,Torregrossa MV,Romano N,Firenze A

更新日期：2011-02-04 00:00:00

abstract：:Neisseria meningitidis can cause severe and fulminant diseases such as meningitis. Meningococcal capsular polysaccharide (PS) is a key virulence determinant that is not able to induce immunological memory. Conjugation of PS to a carrier protein can significantly increase the immunogenicity of PS and induce immunologic...

journal_title：Vaccine

authors： Zhang T,Yu W,Wang Y,Hu T

更新日期：2015-06-22 00:00:00

abstract：:Measles virus (MV) vaccine strains use CD46, signaling lymphocyte activation molecule, and nectin-4 in human cells as receptors. Meanwhile, many of them are propagated in primary chicken embryonic fibroblasts (CEFs). Our data revealed that CEFs express a nectin-4 homologous molecule (CEF nectin-4) containing well-cons...

journal_title：Vaccine

authors： Seki F,Someya K,Komase K,Takeda M

更新日期：2016-01-02 00:00:00

abstract：:Helicobacter pylori neutrophil-activating protein (NAP) is a toll-like receptor 2 (TLR2) agonist and potent immunomodulator inducing Th1-type immune response. Here we present data about characterization of the humoral immune response against NAP-tagged antigens, encoded by attenuated measles virus (MV) vector platform...

journal_title：Vaccine

authors： Iankov ID,Federspiel MJ,Galanis E

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Use of a polysaccharide vaccine challenge to demonstrate immunologic memory after priming with capsular group C meningococcal conjugate vaccines (MenCC) risks induction of immunologic hyporesponsiveness. For this reason, MenCC vaccines are now used as probes of immunologic memory, however, no studies have de...

journal_title：Vaccine

authors： Pace D,Khatami A,Attard-Montalto S,Voysey M,Finn A,Faust SN,Heath PT,Borrow R,Snape MD,Pollard AJ

更新日期：2016-12-07 00:00:00

abstract：:Vaccine hesitancy is increasing and failure to vaccinate is well-recognised in Europe as a contributing factor to outbreaks of infectious diseases. In Lothian and Scotland, low vaccine uptake has been seen in migrants - notably in the Polish group who have arrived since 2004. The recent Vaccine Confidence in European ...

journal_title：Vaccine

authors： Gorman DR,Bielecki K,Willocks LJ,Pollock KG

更新日期：2019-05-06 00:00:00

abstract：:The predominant route of HIV infection is through the sexual transmission via M cells. Most of the peptide and protein vaccines show poor transport across the epithelial barrier and are commonly administered by parenteral route. In the present study four HIV peptides from envelope (gp 41-LZ (leucine zipper), gp 41-FD ...

journal_title：Vaccine

authors： Manocha M,Pal PC,Chitralekha KT,Thomas BE,Tripathi V,Gupta SD,Paranjape R,Kulkarni S,Rao DN

更新日期：2005-12-01 00:00:00

abstract：:Since 2005, the Government of the United States of America has provided more than US$ 50 million to advance influenza vaccine development in low-resourced countries. This programme has provided a unique opportunity for the US Government to develop a comprehensive view of, and to understand better the challenges and fu...

journal_title：Vaccine

authors： Perdue ML,Bright RA

更新日期：2011-07-01 00:00:00

abstract：:This study evaluated the attenuated Salmonella Enteritidis (SE) ghost strain JOL2114 (Δlon ΔcpxR Δasd), which displays on the bacterial surface the H1N1 hemagglutinin globular head portion (HA1; amino acid residues 63-286) on the bacterial surface for protective efficacy against Salmonella and H1N1 challenge in the ch...

journal_title：Vaccine

authors： Won G,Senevirathne A,Lee JH

更新日期：2020-06-09 00:00:00

abstract：:Hepatitis B virus (HBV) infection and HBV-associated diseases are prevalent in many parts of the Middle East and North Africa. Postnatal horizontal childhood transmission appears to be the predominant method by which high hepatitis B carrier rates are maintained. To control hepatitis B in this region, mass immunizatio...

journal_title：Vaccine

authors： Toukan A

更新日期：1990-03-01 00:00:00

abstract：:The immunopotentiating activities of colloidal iron hydroxide, a novel, experimental mineral adjuvant, and of aluminium hydroxide. the licensed adjuvant for human vaccines, were compared. Our studies revealed that colloidal iron hydroxide and aluminium hydroxide behaved comparably with respect to supporting induction ...

journal_title：Vaccine

authors： Leibl H,Tomasits R,Brühl P,Kerschbaum A,Eibl MM,Mannhalter JW

更新日期：1999-03-05 00:00:00

abstract：INTRODUCTION:Institutionalized mentally retarded subjects are well-known to be at-risk for HBV infection. We studied the persistence of vaccine-induced anti-HBs antibodies and the robustness of the HBsAg-specific immune memory in this population, 18-20 years after the first vaccine dose. MATERIALS AND METHODS:Non-immu...

journal_title：Vaccine

authors： Braeckman T,Van Herck K,Jilg W,Bauer T,Van Damme P

更新日期：2012-07-06 00:00:00

abstract：:Cellular proteins that support influenza virus infection represent potential therapeutic targets. Cytoplasmic egress intermediates of influenza A/WSN/33 were isolated and shown to be associated with the cellular enzymes peroxiredoxins-1 (Prdx-1) during glycerol gradient fractionation. Prdx-1 also co-localizes with inf...

journal_title：Vaccine

authors： Dai X,Li N,Roller RJ

更新日期：2018-07-16 00:00:00

abstract：:The development of effective vaccines against serogroup B meningococci is of great public health importance. We assessed a novel genetically engineered vaccine containing six meningococcal class 1 (PorA) outer membrane proteins representing 80% of prevalent strains in the UK. 103 infants were given the meningococcal v...

journal_title：Vaccine

authors： Cartwright K,Morris R,Rümke H,Fox A,Borrow R,Begg N,Richmond P,Poolman J

更新日期：1999-06-04 00:00:00

abstract：:Swine influenza virus (SIV) is not only an important respiratory pathogen in pigs but also a potent threat to human health. Although immunization with recombinant poxviruses expressing protective antigens as vaccines has been widely used for against many infectious diseases, development of recombinant swinepox virus (...

journal_title：Vaccine

authors： Xu J,Huang D,Liu S,Lin H,Zhu H,Liu B,Lu C

更新日期：2012-04-26 00:00:00

abstract：:Virus-like particles (VLPs) are excellent tools for vaccines against pathogens and tumors. They can accommodate foreign polypeptides whose incorporation efficiency and immunogenicity however decrease strongly with the increase of their size. We recently described the CD8(+) T cell immune response against a small forei...

journal_title：Vaccine

authors： Sistigu A,Bracci L,Valentini M,Proietti E,Bona R,Negri DR,Ciccaglione AR,Tritarelli E,Nisini R,Equestre M,Costantino A,Marcantonio C,Santini SM,Lapenta C,Donati S,Tataseo P,Miceli M,Cara A,Federico M

更新日期：2011-04-18 00:00:00

abstract：:The epidemiology of infection due to Haemophilus influenzae type b (Hib) varies in different groups of Australian and New Zealand children. In most populations the annual case attack rate is approximately 40-60 per 100,000 children under 5 years of age and epiglottitis accounts for a relatively high but variable propo...

journal_title：Vaccine

authors： Gilbert GL

更新日期：1991-06-01 00:00:00

abstract：:We cloned six mycobacterial antigens into a mammalian expression vector as fusion proteins with the enhanced green fluorescent protein (EGFP). Plasmid DNA was injected intramuscularly, and the injection sites were examined 1 week later. Expression of each antigen-EGFP fusion protein was visualized as green fluorescenc...

journal_title：Vaccine

authors： Quinn A,Jiang W,Velaz-Faircloth M,Cobb AJ,Henry SC,Frothingham R

更新日期：2002-08-19 00:00:00

abstract：:Viral vectors are promising vaccine candidates for eliciting suitable Ag-specific immune response. Since Mycobacterium tuberculosis (Mtb) normally enters hosts via the mucosal surface of the lung, the best defense against Mtb is mucosal vaccines that are capable of inducing both systemic and mucosal immunity. Although...

journal_title：Vaccine

authors： Watanabe K,Matsubara A,Kawano M,Mizuno S,Okamura T,Tsujimura Y,Inada H,Nosaka T,Matsuo K,Yasutomi Y

更新日期：2014-03-26 00:00:00