Strategy for the control of hepatitis B virus infection in the Middle East and North Africa. The Middle East Regional Study Group.

abstract：:Neuromuscular diseases (NMDs) encompass a broad spectrum of conditions. Because infections may be relevant to the final prognosis of most NMDs, vaccination appears to be the simplest and most effective solution for protecting NMD patients from vaccine-preventable infections. However, very few studies have evaluated th...

journal_title：Vaccine

authors： Esposito S,Bruno C,Berardinelli A,Filosto M,Mongini T,Morandi L,Musumeci O,Pegoraro E,Siciliano G,Tonin P,Marrosu G,Minetti C,Servida M,Fiorillo C,Conforti G,Scapolan S,Ansaldi F,Vianello A,Castaldi S,Principi N,T

更新日期：2014-10-14 00:00:00

abstract：:The use of viral vectors in heterologous prime-boost regimens to induce potent T cell responses in addition to humoral immunity is a promising vaccination strategy in the fight against malaria. We conducted an open-label, first-in-human, controlled Phase I study evaluating the safety and immunogenicity of Matrix-M adj...

journal_title：Vaccine

authors： Venkatraman N,Anagnostou N,Bliss C,Bowyer G,Wright D,Lövgren-Bengtsson K,Roberts R,Poulton I,Lawrie A,Ewer K,V S Hill A

更新日期：2017-10-27 00:00:00

abstract：:Chikungunya virus is an emerging pathogen initially found in East Africa and currently spread into the Indian Ocean Islands, many regions of South East Asia, and in the Americas. No licensed vaccines against this eminent pathogen are available and thus intensive research in this field is a priority. This review presen...

journal_title：Vaccine

authors： Salazar-González JA,Angulo C,Rosales-Mendoza S

更新日期：2015-07-17 00:00:00

abstract：:The aim of this study was to evaluate an experimental Salmonella Enteritidis (SE) bacterin and an indirect ELISA system to assess quantitatively the acquired immunity in Awassi ewes to the vaccine and/or Echinacea purpurea (EP) dried roots. Four treatments of the ewes were included in the experimental design, with 6 e...

journal_title：Vaccine

authors： Barbour EK,Assi CAA,Shaib H,Hamadeh S,Murtada M,Mahmoud G,Yaghmoor S,Iyer A,Harakeh S,Kumosani T

更新日期：2015-05-05 00:00:00

abstract：:Measles transmission has been well documented in healthcare facilities. Healthcare personnel who are unvaccinated and who lack other evidence of measles immunity put themselves and their patients at risk for measles. We conducted a systematic literature review of measles vaccination policies and their implementation i...

journal_title：Vaccine

authors： Fiebelkorn AP,Seward JF,Orenstein WA

更新日期：2014-08-27 00:00:00

abstract：:A qualitative study design was adapted to explore the challenges faced by health workers (HWs) during the polio health campaign. In addition, HWs' opinions about the factors causing parents to refuse oral polio vaccination (OPV) were also explored. Four focus group discussions (FGDs) were held (from 1st January 2015-3...

journal_title：Vaccine

authors： Khan TM,Sahibzada MU

更新日期：2016-04-19 00:00:00

abstract：:Synthetic oligonucleotides (ODNs) containing immunostimulatory CpG motifs (CpG) are a new class of adjuvants suitable for the development of recombinant vaccines. Here we describe that endogenous interferon (IFN) was critical for the adjuvant activity of CpG ODN as genetically deficient mice developed significantly lo...

journal_title：Vaccine

authors： Rosa DS,Bastos KR,Bargieri DY,Tzelepis F,Nomizo A,Russo M,Soares IS,Rodrigues MM

更新日期：2007-08-10 00:00:00

abstract：:Safety of individuals at risk of immune suppression is an important concern for live vaccines. The new-generation tuberculosis vaccine candidate MTBVAC, a genetically engineered doubly attenuated Mycobacterium tuberculosis mutant with deletions in phoP and fadD26 virulence genes has demonstrated comparable safety in d...

journal_title：Vaccine

authors： Solans L,Uranga S,Aguilo N,Arnal C,Gomez AB,Monzon M,Badiola JJ,Gicquel B,Martin C

更新日期：2014-09-08 00:00:00

abstract：:While the large majority of parents in the U.S. vaccinate their children according to the recommended immunization schedule, some parents have refused or delayed vaccinating, often citing safety concerns. In response to public concern, the U.S. Institute of Medicine (IOM) evaluated existing research regarding the safe...

journal_title：Vaccine

authors： Glanz JM,Newcomer SR,Jackson ML,Omer SB,Bednarczyk RA,Shoup JA,DeStefano F,Daley MF

更新日期：2016-02-15 00:00:00

abstract：:In this review we aim to provide the reader with an understanding of the capsular-based complexity of Streptococcus pneumoniae, one of the main limitations to current vaccine development. We then discuss the need for a new vaccine strategy based on proteic antigen candidates discovered in silico. Describing specifical...

journal_title：Vaccine

authors： Barocchi MA,Censini S,Rappuoli R

更新日期：2007-04-20 00:00:00

abstract：:Conflicting findings regarding the level of protection offered by seasonal influenza vaccination against pandemic influenza H1N1 have been reported. We performed a test-negative case control study using sentinel patients from general practices in Victoria to estimate seasonal influenza vaccine effectiveness against la...

journal_title：Vaccine

authors： Kelly HA,Grant KA,Fielding JE,Carville KS,Looker CO,Tran T,Jacoby P

更新日期：2011-08-26 00:00:00

abstract：:Different subsets of dendritic cells (DC) elicit qualitatively different immune responses. In mice, two lymphoid tissue-resident subsets, CD8α(+) and CD8α(-), have been implicated in the induction of T helper 1 (Th1) or Th2 responses, respectively. Moreover, CD8α(+) DC appear to play a major role in priming CD8(+) T l...

journal_title：Vaccine

authors： Suleman M,Galea S,Gavard F,Merillon N,Klonjkowski B,Tartour E,Richardson J

更新日期：2011-08-11 00:00:00

abstract：:The ability of ALVAC- or fowlpox-based simian immunodeficiency virus (SIV) vaccines to boost SIV-specific CD4+ and CD8+ T-cell responses was tested in 10 vaccinia-experienced macaques infected with SIVmac251. The CD8+ T-cell response to the dominant Gag(181-189) CM9 was quantitated in seven Mamu-A*01-positive macaques...

journal_title：Vaccine

authors： Nacsa J,Radaelli A,Edghill-Smith Y,Venzon D,Tsai WP,Morghen Cde G,Panicali D,Tartaglia J,Franchini G

更新日期：2004-01-26 00:00:00

abstract：:Hepatitis B is a parenterally and sexually transmitted disease of global importance. It associates with hepatitis D in a consistent proportion of cases. The disease most frequently runs a subclinical and anicteric course, with a significant number of cases that become chronic. Chronic hepatitis may progress to cirrhos...

journal_title：Vaccine

authors： Nisini R,Rizzetto M

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Vaccination coverage in Bosnia and Herzegovina has been declining over recent years. A World Health Organization Tailoring Immunization Programmes (TIP) project is underway to gain insights into the underlying reasons for this, to develop tailored interventions. As part of TIP, this study aimed to investigat...

journal_title：Vaccine

authors： Musa S,Skrijelj V,Kulo A,Habersaat KB,Smjecanin M,Primorac E,Becirovic D,Jackson C

更新日期：2020-02-18 00:00:00

abstract：UNLABELLED:The Internet contains a large amount of useful information on many subjects, but also information of doubtful quality. To help identify Web sites on vaccine safety that fulfil good practice, the Global Advisory Committee on Vaccine Safety of the World Health Organization (WHO) has published criteria to which...

journal_title：Vaccine

authors： Martínez-Mora M,Alvarez-Pasquín MJ,Rodríguez-Salvanés F

更新日期：2008-12-09 00:00:00

abstract：:The main objective of this study was to assess the efficacy of a monovalent inactivated vaccine containing phase I Coxiella burnetii to prevent Coxiella shedding in susceptible dairy cows within infected herds in comparison to a placebo. A total of 336 dairy cows and heifers, from six spontaneously infected herds, wer...

journal_title：Vaccine

authors： Guatteo R,Seegers H,Joly A,Beaudeau F

更新日期：2008-08-12 00:00:00

abstract：:The purpose of this paper is to propose new evaluation criteria and an analytic hierarchy process (AHP) model to assess the expanded national immunization programs (ENIPs) and to evaluate two alternative health care policies. One of the alternative policies is that private clinics and hospitals would offer free vaccin...

journal_title：Vaccine

authors： Shin T,Kim CB,Ahn YH,Kim HY,Cha BH,Uh Y,Lee JH,Hyun SJ,Lee DH,Go UY

更新日期：2009-01-29 00:00:00

abstract：:DNA immunization with HIV envelope plasmids induce only moderate levels of specific antibodies which may in part be due to limitations in expression influenced by a species-specific and biased HIV codon usage. We compared antibody levels, Th1/Th2 type and CTL responses induced by synthetic genes encoding membrane boun...

journal_title：Vaccine

authors： Vinner L,Nielsen HV,Bryder K,Corbet S,Nielsen C,Fomsgaard A

更新日期：1999-04-23 00:00:00

abstract：:Measles, mumps, rubella and varicella are viral infections which can implicate seriously long-term sequelae of infected individuals or even the unborn child. Vaccines against the individual diseases have long been available. Global measles vaccination is estimated to have prevented more than 20million deaths during 20...

journal_title：Vaccine

authors： Kowalzik F,Faber J,Knuf M

更新日期：2018-08-28 00:00:00

abstract：:110 children who were given the complete course of the inactivated hepatitis A vaccine (Havrix) were followed up 10 years later. Age-matched healthy children who were not inoculated served as controls. One month after two primary injections, all children were positive for serum antibody. After 10 years, 99.09% of inoc...

journal_title：Vaccine

authors： Bian GL,Ma R,Dong HJ,Ni HX,Hu FJ,Chen YR,Chen JQ,Zhou SY,Lin YX,Xu GZ

更新日期：2010-07-05 00:00:00

abstract：INTRODUCTION:Vaccination of pregnant women protects both women and their newborns against some infectious diseases. Thailand implemented tetanus toxoid (TT) vaccination of pregnant women in 1977, which was replaced by tetanus-diphtheria toxoid (dT) vaccination in 2005. The tetanus-diphtheria-acellular pertussis (Tdap) ...

journal_title：Vaccine

authors： Wanlapakorn N,Maertens K,Thongmee T,Srimuan D,Thatsanathorn T,Van Damme P,Leuridan E,Poovorawan Y

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:Streptococcus pyogenes (group A Streptococcus, Strep A) is a widespread pathogen that continues to pose a significant threat to human health. The development of a Strep A vaccine remains an unmet global health need. One of the major vaccine strategies is the use of M protein, which is a primary virulence det...

journal_title：Vaccine

authors： Pastural É,McNeil SA,MacKinnon-Cameron D,Ye L,Langley JM,Stewart R,Martin LH,Hurley GJ,Salehi S,Penfound TA,Halperin S,Dale JB

更新日期：2020-02-05 00:00:00

abstract：:The safety and immunogenicity of two conjugate Haemophilus influenzae type B (Hib) vaccines administered either mixed with, or in separate limbs to, a whole-cell DTP vaccine, was compared in infants vaccinated at 2, 3 and 4 months of age. Antibody titres to purified polyribosylribitol phosphate, diphtheria, and to per...

journal_title：Vaccine

authors： Begg NT,Miller E,Fairley CK,Chapel HM,Griffiths H,Waight PA,Ashworth LA

更新日期：1995-11-01 00:00:00

abstract：:Two hundred health care workers in England and Wales were vaccinated with the Lister/Elstree strain of the vaccinia virus, and completed health diaries for 21 days or until the lesion had scabbed over. Pain and temperature were measured daily, and all other symptoms recorded freehand by the vaccinee. One hundred and f...

journal_title：Vaccine

authors： Auckland C,Cowlishaw A,Morgan D,Miller E

更新日期：2005-07-14 00:00:00

abstract：:Small fusions to the N-terminal end of the host-protective antigen (VP2) of infectious bursal disease virus lead to stable expression of VP2 in Escherichia coli and yeast, and reduce the levels of inclusion body formation in E. coli in comparison to VP2 constructs with larger N-terminal fusions. VP2 produced with smal...

journal_title：Vaccine

authors： Azad AA,McKern NM,Macreadie IG,Failla P,Heine HG,Chapman A,Ward CW,Fahey KJ

更新日期：1991-10-01 00:00:00

abstract：:DNA vaccines contribute to a promising new approach for the generation of cytotoxic T lymphocytes (CTL). DNA vaccines do have several disadvantages, including poor immunogenicity and oncogene expression. We used the natural killer T-cell (NKT) ligand α-galactosylceramide (α-GalCer) as an adjuvant to prime initial DNA ...

journal_title：Vaccine

authors： Kim D,Hung CF,Wu TC,Park YM

更新日期：2010-10-21 00:00:00

abstract：:Pneumococcal infection is a leading cause of adult morbidity and mortality in the United States. Immunization against this infection is a valuable strategy in preventive medicine. An effective pneumococcal vaccine has been available in this country for over a decade, but it remains poorly utilized. The purpose of the ...

journal_title：Vaccine

authors： Rushton TC,Ganguly R,Sinnott JT 4th,Banerji M

更新日期：1994-10-01 00:00:00

abstract：INTRODUCTION:Since the launch of the Global Polio Eradication Initiative (GPEI) in 1988, there has been a tremendous progress in the reduction of cases of poliomyelitis. The world is on the verge of achieving global polio eradication and in May 2013, the 66th World Health Assembly endorsed the Polio Eradication and End...

journal_title：Vaccine

authors： Mwengee W,Okeibunor J,Poy A,Shaba K,Mbulu Kinuani L,Minkoulou E,Yahaya A,Gaturuku P,Landoh DE,Nsubuga P,Salla M,Mihigo R,Mkanda P

更新日期：2016-10-10 00:00:00

abstract：:Since 2000, there has been a legal requirement in the UK that dogs and cats should have an effective rabies vaccination with demonstrable sero-conversion if their owners wish to avoid quarantine on re-entry to the UK. In 2002, 10,483 rabies titres were determined on dogs at the VLA. Statistical analyses assessed the e...

journal_title：Vaccine

authors： Kennedy LJ,Lunt M,Barnes A,McElhinney L,Fooks AR,Baxter DN,Ollier WE

更新日期：2007-12-12 00:00:00