Immune responses and protective efficacy of a recombinant swinepox virus expressing HA1 against swine H1N1 influenza virus in mice and pigs.

abstract：:The baculovirus-insect cell expression system is a well known tool for the production of complex proteins. The technology is also used for commercial manufacture of various veterinary and human vaccines. This review paper provides an overview of how this technology can be applied to produce a multitude of vaccine cand...

journal_title：Vaccine

authors： Cox MM

更新日期：2012-02-27 00:00:00

abstract：OBJECTIVES:Adoption of human papillomavirus (HPV) vaccination in the US has been slow. In 2011, HPV vaccination of boys was recommended by CDC for routine use at ages 11-12. We conducted and evaluated a social marketing intervention with parents and providers to stimulate HPV vaccination among preteen boys. METHODS:We...

journal_title：Vaccine

authors： Cates JR,Diehl SJ,Crandell JL,Coyne-Beasley T

更新日期：2014-07-16 00:00:00

abstract：INTRODUCTION:In 2005, in Finland, the whole-cell pertussis vaccine was replaced by acellular given at 3-5-12months, and boosters at 4 and 11-15years of age. From July 2012, military conscripts have been offered a pertussis booster dose. Conscription is mandatory for Finnish men, and >95% were 19-21years old when enroll...

journal_title：Vaccine

authors： Zöldi V,Sane J,Nohynek H,Virkki M,Hannila-Handelberg T,Mertsola J

更新日期：2017-09-18 00:00:00

abstract：:Liposome and cholera toxin (CT) are considered to be effective antigen delivery vehicles and adjuvants for mucosal vaccines. The effect of these antigen delivery systems on adjuvant responses to mucosally administered pneumococcal polysaccharide (Pnup) was investigated in this study. Both mucosal (e.g. oral) and syste...

journal_title：Vaccine

authors： VanCott JL,Kobayashi T,Yamamoto M,Pillai S,McGhee JR,Kiyono H

更新日期：1996-04-01 00:00:00

abstract：:To generate CD4+ T-helper cell lines, lymphocytes from HIV-seronegative subjects were primed in vitro with peptides derived from the V3 loop of HIV-1 gp120. Antigen-specific reactivity was inhibited by an anti-DR monoclonal antibody, indicating HLA-class II dependency, but peptides could be recognized in different HLA...

journal_title：Vaccine

authors： Billaud JN,Yagello M,Gluckman JC

更新日期：1994-01-01 00:00:00

abstract：:Since 1992, hepatitis B vaccine has been an integrated part of Thailand's expanded programme on immunisation (EPI). Based on the data from five representative provinces, we have evaluated its impact on the countrywide prevalence of HBV infection and carrier rate. The population studied comprised 400-488 healthy and im...

journal_title：Vaccine

authors： Poovorawan Y,Theamboonlers A,Vimolket T,Sinlaparatsamee S,Chaiear K,Siraprapasiri T,Khwanjaipanich S,Owatanapanich S,Hirsch P,Chunsuttiwat S

更新日期：2000-11-22 00:00:00

abstract：BACKGROUND:Influenza vaccination is recommended for immunocompromised patients. METHODS:Children (6 months to 21 years) with cancer, HIV infection, or sickle cell disease (SCD) received 1 or 2 doses of pandemic 2009 H1N1 monovalent influenza vaccine (H1N1 MIV). Safety and tolerability, hemagglutination inhibition (HI)...

journal_title：Vaccine

authors： Hakim H,Allison KJ,Van De Velde LA,Li Y,Flynn PM,McCullers JA

更新日期：2012-01-20 00:00:00

abstract：:Interferon-gamma (IFN-gamma) has potent immune stimulatory activity, but purifying recombinant protein is expensive, soluble cytokine delivery is inefficient, and high doses of IFN-gamma cause adverse systemic effects. We've shown, however, that chemically fixed, amended recombinant Pseudomonas fluorescens cells (ARCs...

journal_title：Vaccine

authors： Gaertner FH,Babiuk LA,Mutwiri G,Armstrong JM,Griebel PJ

更新日期：2009-02-25 00:00:00

abstract：:Effects of cholera toxin B subunits supplemented with 0.1% cholera toxin (CTB*) on systemic IgE antibody responses to ovalbumin (OVA) were examined in BDFI (H-2b/d), Balb/c (H-2d) and C3H (H-2k) mice given OVA intragastrically or intranasally. Two successive doses of OVA intragastrically administered to Balb/c and C3H...

journal_title：Vaccine

authors： Tamura S,Shoji Y,Hasiguchi K,Aizawa C,Kurata T

更新日期：1994-10-01 00:00:00

abstract：:Previously, we showed that intracutaneous vaccination of rabbits with DNA vectors encoding ubiquitin-fused versions of the cottontail rabbit papillomavirus (CRPV) early proteins E1, E2, E6 and E7 protected against subsequent challenge with CRPV. Here, we tested the immunotherapeutic activity of a vaccine composed of t...

journal_title：Vaccine

authors： Brandsma JL,Shlyankevich M,Zelterman D,Su Y

更新日期：2007-08-14 00:00:00

abstract：:Rhesus-human rotavirus reassortants incorporating the gene expressing the VP7 surface protein of human rotavirus serotypes 1 or 2, and the remaining ten genes from rhesus rotavirus (RRV) were evaluated as candidate oral vaccines in 2-4-month-old infants. A single dose of the serotype 1 reassortant vaccine which had a ...

journal_title：Vaccine

authors： Vesikari T,Varis T,Green K,Flores J,Kapikian AZ

更新日期：1991-05-01 00:00:00

abstract：:Development of effective new mucosal vaccine adjuvants has become a priority with the increase in emerging viral and bacterial pathogens. We previously reported that cationic liposomes complexed with non-coding plasmid DNA (CLDC) were effective parenteral vaccine adjuvants. However, little is known regarding the abili...

journal_title：Vaccine

authors： Henderson A,Propst K,Kedl R,Dow S

更新日期：2011-07-18 00:00:00

abstract：:Potential endpoints for blood stage malaria vaccine efficacy trials include uncomplicated malaria disease, which is hard to differentiate from other febrile illnesses, and mortality, which requires prohibitively large sample sizes. Strictly defined severe malaria predicts malaria-associated mortality where case fatali...

journal_title：Vaccine

authors： Lyke KE,Dicko A,Kone A,Coulibaly D,Guindo A,Cissoko Y,Traoré K,Plowe CV,Doumbo OK

更新日期：2004-08-13 00:00:00

abstract：:Neuromuscular diseases (NMDs) encompass a broad spectrum of conditions. Because infections may be relevant to the final prognosis of most NMDs, vaccination appears to be the simplest and most effective solution for protecting NMD patients from vaccine-preventable infections. However, very few studies have evaluated th...

journal_title：Vaccine

authors： Esposito S,Bruno C,Berardinelli A,Filosto M,Mongini T,Morandi L,Musumeci O,Pegoraro E,Siciliano G,Tonin P,Marrosu G,Minetti C,Servida M,Fiorillo C,Conforti G,Scapolan S,Ansaldi F,Vianello A,Castaldi S,Principi N,T

更新日期：2014-10-14 00:00:00

abstract：:Pneumococcal and Salmonella typhi infections are two major diseases for children in developing countries. For typhoid fever, licensed Vi polysaccharide vaccines are ineffective in children <2-year old. While investigational Vi conjugate vaccines have been shown effective in clinical trials, they are currently only ava...

journal_title：Vaccine

authors： Lu YJ,Zhang F,Sayeed S,Thompson CM,Szu S,Anderson PW,Malley R

更新日期：2012-05-14 00:00:00

abstract：:Seasonal influenza vaccines represent a positive intervention to limit the spread of the virus and protect public health. Yet continual influenza evolution and its ability to evade immunity pose a constant threat. For these reasons, vaccines with improved potency and breadth of protection remain an important need. We ...

journal_title：Vaccine

authors： Rudicell RS,Garinot M,Kanekiyo M,Kamp HD,Swanson K,Chou TH,Dai S,Bedel O,Simard D,Gillespie RA,Yang K,Reardon M,Avila LZ,Besev M,Dhal PK,Dharanipragada R,Zheng L,Duan X,Dinapoli J,Vogel TU,Kleanthous H,Mascola J

更新日期：2019-09-30 00:00:00

abstract：:A conjugate vaccine against meningococcus A and C was prepared using the non-toxic mutant of diphtheria toxin CRM 197 as a carrier protein. Capsular polysaccharides of Neisseria meningitidis group A and C were hydrolysed and the resulting oligosaccharides were then coupled to CRM 197 in order to obtain conjugates with...

journal_title：Vaccine

authors： Costantino P,Viti S,Podda A,Velmonte MA,Nencioni L,Rappuoli R

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Despite being committed to the immunization agenda set by the WHO, Italy is currently experiencing decreasing vaccination rates and increasing incidence of vaccine-preventable diseases. Our aim is to analyze Italian online debates on pediatric immunizations through a content analytic approach in order to qua...

journal_title：Vaccine

authors： Fadda M,Allam A,Schulz PJ

更新日期：2015-12-16 00:00:00

abstract：:Nucleic acid vaccination has many potential advantages over traditional methods, but suffers from the fact that DNA vaccines tend to be relatively poorly immunogenic. Attempts to enhance DNA vaccine immunogenicity have included the addition of cytokine-encoding plasmids into the formulation, as well as the use of hete...

journal_title：Vaccine

authors： Nimal S,McCormick AL,Thomas MS,Heath AW

更新日期：2005-06-10 00:00:00

abstract：:Leishmania donovani promastigote soluble antigens (sLAg) were encapsulated in non-phosphatidylcholine (non-PC) liposomes (escheriosomes) prepared from E. coli lipids. The escheriosome-based vaccine was investigated for its potential to elicit a protective immune response against experimental visceral leishmaniasis. Th...

journal_title：Vaccine

authors： Sharma SK,Dube A,Nadeem A,Khan S,Saleem I,Garg R,Mohammad O

更新日期：2006-03-10 00:00:00

abstract：:Human metapneumovirus (HMPV) is an important cause of acute respiratory tract disease for which the development of vaccine candidates is warranted. We have previously described the generation of an iscom matrix-adjuvanted HMPV fusion protein subunit vaccine (Fsol) and a live-attenuated vaccine (HMPVM11). Here, we eval...

journal_title：Vaccine

authors： Herfst S,Schrauwen EJ,de Graaf M,van Amerongen G,van den Hoogen BG,de Swart RL,Osterhaus AD,Fouchier RA

更新日期：2008-08-05 00:00:00

abstract：:Purified tetanus toxoid, a high-molecular-weight protein, was entrapped within poly(L-lactic acid) (PLA) and poly(D,L-lactic/glycolic acid) (PLGA) microspheres prepared by either a solvent extraction or a solvent evaporation method carried out in a multiple emulsion system (water-in-oil-in-water). The physical integri...

journal_title：Vaccine

authors： Alonso MJ,Gupta RK,Min C,Siber GR,Langer R

更新日期：1994-03-01 00:00:00

abstract：:Cattle produce specific serum antibody mainly of the IgG1 isotype in response to infection with the liver fluke, Fasciola hepatica. In these animals a positive correlation between fluke-specific serum IgG1 levels and fluke-burden in non-immunized infected animals was observed. In contrast, immunization of cattle with ...

journal_title：Vaccine

authors： Mulcahy G,O'Connor F,McGonigle S,Dowd A,Clery DG,Andrews SJ,Dalton JP

更新日期：1998-05-01 00:00:00

abstract：:This study compared responses of bison calves to 10(10)CFU of Brucella abortus strain RB51 (SRB51) delivered by parenteral or ballistic methods. Two types of biobullet payloads were evaluated; compacted SRB51 pellets or SRB51 encapsulated in photopolymerized poly(ethylene glycol) hydrogels. Bison were vaccinated with ...

journal_title：Vaccine

authors： Olsen SC,Christie RJ,Grainger DW,Stoffregen WS

更新日期：2006-02-27 00:00:00

abstract：:The prevalence of hepatitis B virus (HBV) infection and its sequelae vary widely in the different populations living in the Asian-Pacific region. Horizontal transmission plays an important role in the spread of the disease; in East Asia, however, maternal transmission is particularly significant since a high portion o...

journal_title：Vaccine

authors： Sung JL

更新日期：1990-03-01 00:00:00

abstract：:Smallpox eradication, coordinated by the WHO and certified 40 years ago, led to the cessation of routine smallpox vaccination in most countries. It is estimated that over 70% of the world's population is no longer protected against smallpox, and through cross-immunity, to closely related orthopox viruses such as monke...

journal_title：Vaccine

authors： Simpson K,Heymann D,Brown CS,Edmunds WJ,Elsgaard J,Fine P,Hochrein H,Hoff NA,Green A,Ihekweazu C,Jones TC,Lule S,Maclennan J,McCollum A,Mühlemann B,Nightingale E,Ogoina D,Ogunleye A,Petersen B,Powell J,Quantick O

更新日期：2020-07-14 00:00:00

abstract：:We have previously shown that vaccination of BALB/c mice with a combination of BCG plus killed Leishmania promastigotes, applied by the i.p. route 10 and 3 days before Trypanosoma cruzi inoculation, prolonged their survival and decreased their parasitaemia. In the present study we show that the BCG-Leishmania vaccine ...

journal_title：Vaccine

authors： Araujo Z,Heremans H,Stordeur P,Wissing M,Goldman M,Castes M,Carlier Y

更新日期：2000-03-06 00:00:00

abstract：:Evidence has accumulated supporting the relationship between the use of 7-valent pneumococcal conjugate vaccine (PCV7) in children and a decline in invasive pneumococcal disease (IPD) in the elderly. We conducted a state-level analysis of vaccination coverage rates among children 19-35 months of age and IPD hospitaliz...

journal_title：Vaccine

authors： McBean AM,Jung K,Hebert PL

更新日期：2006-07-07 00:00:00

abstract：:African horse sickness is a lethal viral disease of equids transmitted by biting midges of the Genus Culicoides. The disease is endemic to sub-Saharan Africa but outbreaks of high mortality and economic impact have occurred in the past in non-endemic regions of Africa, Asia and Southern Europe. Vaccination is critical...

journal_title：Vaccine

authors： Manning NM,Bachanek-Bankowska K,Mertens PPC,Castillo-Olivares J

更新日期：2017-10-20 00:00:00

abstract：:Human papillomavirus (HPV)-related morbidity and mortality from cervical cancer primarily occurs in the developing world, where, unfortunately, access to vaccines in general, and expensive newer vaccines in particular, is often more limited than in the industrialized world. In addition, secondary prevention methods su...

journal_title：Vaccine

authors： Kane MA,Sherris J,Coursaget P,Aguado T,Cutts F

更新日期：2006-08-31 00:00:00