Dyshormonal disorders in gout: experimental and clinical studies.

abstract：:Carbacholine reduced, while baclofen and norepinephrine increased resting membrane potential in earthworm somatic muscle cells. In the presence of carbacholine, neither norepinephrine, nor baclofen hyperpolarized the membrane. Ouabain decreased resting potential and abolished the effects of carbacholine, norepinephrin...

journal_title：Bulletin of experimental biology and medicine

authors： Volkov EM,Sabirova AR,Volkov ME,Zefirov AL

更新日期：2007-08-01 00:00:00

abstract：:Study of the early embryogenesis process based on the previously suggested scheme of epithelial cambial cell work has shown that cambial (or stem) cells originate from the primary ectoderm and intensely express RhoA protein and slightly express Src kinase. This explains their stem properties and the absence of differe...

journal_title：Bulletin of experimental biology and medicine

authors： Yavisheva TM,Shcherbakov SD

更新日期：2012-05-01 00:00:00

abstract：:We studied the effects of optical (dd-, ll-, dl-, and ld-dipeptides with alpha-bond, EW) structural isomers and cyclic (dd-, ll-, dl-, and ld-dipeptides with gamma-bond, iEW) analogs of Glu-Trp synthetic dipeptide on the population of normal hemopoietic stem cells. Dipeptides containing lGlu (lGlu-lTrp, lGlu-dTrp) inj...

journal_title：Bulletin of experimental biology and medicine

authors： Semina OV,Semenets TN,Zamulaeva IA,Selivanova EI,Malyutina YV,Saenko AS,Deigin VI

更新日期：2006-02-01 00:00:00

abstract：:The effect of epithalamin on circadian rhythms of thymic serum factor titers and melatonin concentrations in the blood of elderly people was studied. Course treatment with epithalamin modulated the rhythm of the thymic endocrine function. The increase in the titer of thymic serum factor at night coincided with the inc...

journal_title：Bulletin of experimental biology and medicine

authors： Labunets IF,Butenko GM,Magdich LV,Korkushko OV,Khavinson VKh,Shatilo VB

更新日期：2004-05-01 00:00:00

abstract：:We performed morphofunctional analysis of cultured rabbit buccal epithelial cells in the primary culture, during passaging, and upon interaction with collagen substrates. Three different morphological types were identified. It was demonstrated that precursors of rabbit buccal epithelium were characterized by high prol...

journal_title：Bulletin of experimental biology and medicine

authors： Chentsova EV,Konyushko OI,Makarov MS,Egorova NS,Zinov'ev MY,Borovkova NV

更新日期：2015-05-01 00:00:00

abstract：:Polymorphic variants of CYP1A2 and CYP2D6 genes of the cytochrome P450 system were studied in patients with schizophrenia with drug-induced motor disorders and hyperprolactinemia against the background of long-term neuroleptic therapy. We revealed an association of polymorphic variant C-163A CYP1A2*1F of CYP1A2 gene w...

journal_title：Bulletin of experimental biology and medicine

authors： Ivanova SA,Filipenko ML,Vyalova NM,Voronina EN,Pozhidaev IV,Osmanova DZ,Ivanov MV,Fedorenko OY,Semke AV,Bokhan NA

更新日期：2016-03-01 00:00:00

abstract：:Treadmill training of spinalized rats creates conditions for early appearance of rhythmic locomotor movements of the hind limbs. Recovery of the movements was paralleled by an appropriate structural organization of neurons in the anterior horns of the distal compartment of the spinal cord. ...

journal_title：Bulletin of experimental biology and medicine

authors： Moshonkina TR,Gilerovich EG,Fedorova EA,Avelev VD,Gerasimenko YP,Otellin VA

更新日期：2004-08-01 00:00:00

abstract：:Delivery of plasmid DNA and interfering RNA into adipose tissue stromal cells was carried out by the methods of lipofection, calcium phosphate method, and by electroporation. The percent of transfected cells after delivery of plasmid DNA by the calcium phosphate method and lipofection was 0 and 15%, respectively, vs. ...

journal_title：Bulletin of experimental biology and medicine

authors： Lopatina TV,Kalinina NI,Parfyonova EV

更新日期：2009-04-01 00:00:00

abstract：:We studied mesenchymal stem cells from human bone marrow, adipose tissue, skin, placenta, and thymus. Morphological study and cytofluorometrical analysis by the main marker genes (CD10, CD13, CD31, CD44, CD90, CD105) were carried out. Mesemchymal stem cells of the studied tissues during isolation and culturing were mo...

journal_title：Bulletin of experimental biology and medicine

authors： Musina RA,Bekchanova ES,Sukhikh GT

更新日期：2005-04-01 00:00:00

abstract：:Comparative analysis of the efficiency of PCR and microbiological methods for deciphering of the etiological structure of non-nosocomial pneumonias demonstrated the diagnostic significance of detecting Streptococcus pneumoniae DNA in the blood, but not sputum. Mechanisms of penetration of S. pneumoniae into the blood ...

journal_title：Bulletin of experimental biology and medicine

authors： Artemova LV,Beskhlebnaya VA,Ezhova LG,Kirillov MY,Kravtsov EG,Dalin MV

更新日期：2003-10-01 00:00:00

abstract：:The peculiarities of the histological structure and morphometrical parameters of the dentition in ISIAH rats (inherited stress-induced arterial hypertension) before stress and after modeling of everyday life stress regimen (chronic stress) were compared with those in WAG rats. The area of blood vessels of the periodon...

journal_title：Bulletin of experimental biology and medicine

authors： Kolesnikova LR,Darenskaya MA,Kolesnikova LI,Grebenkina LA,Korytov LI,Batoroev YK,Belinskaya EI,Mikhalevich IM,Kolesnikov SI

更新日期：2019-05-01 00:00:00

abstract：:We studied erythropoiesis in newborn infants delivered by mothers with normal pregnancy and gestosis. The effects of placental extracts on hemopoiesis in JCR mice were also evaluated. Our results suggest that the placenta is involved in the regulation of fetal erythropoiesis. The placenta activates fetal erythropoiesi...

journal_title：Bulletin of experimental biology and medicine

authors： Evseenko DA,Tsirel'nikov NI

更新日期：2001-11-01 00:00:00

abstract：:Chinese hamster cells in culture were blocked in prometaphase by the addition of chloral hydrate. After 2 h the chloral hydrate was removed and the ultrastructural changes in the kinetochore studied during recovery of mitosis. The kinetochore in the blocked cells is a disc measuring 300-350 nm in diameter and 30-35 nm...

journal_title：Bulletin of experimental biology and medicine

authors： Alov IA,Lyubskii SL

更新日期：1975-01-01 00:00:00

abstract：:Circadian dynamics of rectal reactivity was studied in humans with regular and irregular rhythms of bowel evacuation function by chronoenterography. In individuals with regular rhythm of this function (stool 7 days per week) the acrophase of circadian rhythm of rectal reactivity was observed in morning hours, while in...

journal_title：Bulletin of experimental biology and medicine

authors： Shemerovskii KA

更新日期：2002-12-01 00:00:00

abstract：:Delayed consequences of acute hypoxia were studied in 60-day-old rat pups. The animals were exposed to acute hypobaric hypoxia on day 10 of embryogenesis. The offspring of intact females served as the control. Reactivity of mesenteric lymphatic vessels to norepinephrine was studied by vital microscopy. The frequency a...

journal_title：Bulletin of experimental biology and medicine

authors： Sanzhieva LTs,Graf AS,Maslova MV,Lelekova TV,Sokolova NA

更新日期：2004-07-01 00:00:00

abstract：:We developed wound coating based on natural biopolymer chitosan with additional components (ceruloplasmin, L-asparaginic acid, and glycerol). Experiments on albino male rats demonstrated its regeneratory, antioxidant, and antibacterial effects on wounds involving all layers of the skin. Due to chemical composition and...

journal_title：Bulletin of experimental biology and medicine

authors： Gladkova EV,Babushkina IV,Norkin IA,Mamonova IA,Puchin'yan DM,Konyuchenko EA

更新日期：2016-03-01 00:00:00

abstract：:Activation of free radical oxidation and inhibition of antioxidant activity in mouse myocardium after long-term dipyridamole treatment were demonstrated using chemiluminescent techniques. At the same time, dipyridamole 10-fold inhibited free radical oxidation and slightly increased antioxidant activity in the plasma. ...

journal_title：Bulletin of experimental biology and medicine

authors： Ivasenko IN,Shlyakhto EV

更新日期：2001-06-01 00:00:00

abstract：:We studied the effect of constant illumination for 1 month on female GC (genetic catalepsy) and Wistar rats (control). Light exposure decreased the degree of cataleptic freezing in female GC rats (compared to the control). Norepinephrine concentration in cataleptic rats returned to normal under these conditions: this ...

journal_title：Bulletin of experimental biology and medicine

authors： Klotchkov DV,Alekhina TA,Ukolova TN,Rjazanova MA

更新日期：2008-07-01 00:00:00

abstract：:We studied high-resolution (1)H nuclear magnetic resonance spectra of the serum and serum albumin from patients with the first episode of schizophrenia and healthy individuals. A relative increase in signal intensities of CH(2) protons in serum LDL and VLDL in schizophrenia was demonstrated. Higher intensities of CH(2...

journal_title：Bulletin of experimental biology and medicine

authors： Babushkina TA,Klimova TP,Peregudov AS,Gryzunov YA,Smolina NV,Dobretsov GE,Uzbekov MG

更新日期：2012-04-01 00:00:00

abstract：:In mature rats, electrical stimulation of the retrotrapezoid nucleus increased the amplitude and frequency of the high-frequency peak in the firing spectrum of the phrenic nerve, while the amplitude of medium-frequency peak and the amplitude ratio of medium- to high-frequency peaks decreased. These changes in spectral...

journal_title：Bulletin of experimental biology and medicine

authors： Tatarnikov VS

更新日期：2004-08-01 00:00:00

abstract：:The rats were divided into groups demonstrating extremely high and low stress reactivity depending on the results of testing for the nociceptive threshold and thermolability in response to bacterial lipopolysaccharide administration. Specific structural features of the nucleus and mitochondria were revealed in neurons...

journal_title：Bulletin of experimental biology and medicine

authors： Potanin MB,Tumanov VP,Pisarev VB

更新日期：2007-11-01 00:00:00

abstract：:We studied the effects of SNK-411, a new 5-pyrimidinol derivative, on serum cytokine profile of C57Bl/6 mice with Lewis lung carcinoma. The compound was injected intraperitoneally in doses of 25 and 50 mg/kg. A significant (by 3.5 times) increase in serum IL-4 content was detected in mice with tumors on day 9 of tumor...

journal_title：Bulletin of experimental biology and medicine

authors： Kuznetsova OS,Tallerova AV,Nikitin SV,Kovalenko LP

更新日期：2016-02-01 00:00:00

abstract：:The inotropic response of the myocardium to extrasystolic treatment was studied on isolated perfused papillary muscles from rats with postinfarction cardiosclerosis. The development of postinfarction cardiosclerosis was accompanied by a decrease in myocardial excitability. The amplitude of extrasystolic contractions i...

journal_title：Bulletin of experimental biology and medicine

authors： Kondrat'eva DS,Afanas'ev SA,Falaleeva LP,Shakhov VP

更新日期：2005-06-01 00:00:00

abstract：:In some patients with stable and unstable angina pectoris and in some donors without clinical manifestations of cardiovascular diseases and other pathologies, spontaneous platelet aggregation was completely suppressed by glycoprotein IIb-IIIa antagonists blocking the interaction of this glycoprotein with fibrinogen. A...

journal_title：Bulletin of experimental biology and medicine

authors： Sirotkina OV,Zabotina AM,Taraskina AE,Sivachenko EB,Zueva EE,Kadinskaya MI,Buryachkovskaya LI,Uchitel' IA,Khaspekova SG,Vavilova TV,Shvartsman AL,Mazurov AV

更新日期：2007-04-01 00:00:00

abstract：:Tenoten is a new anxiolytic and antidepressant based on antibodies to brain-specific protein S-100B. Experimental studies demonstrated the effect of tenoten on mechanisms of neuronal plasticity and manifestations of higher nervous activity. Tenoten is clinically comparable with amitryptiline, sertraline, and phenazepa...

journal_title：Bulletin of experimental biology and medicine

authors： Duma SA,Shishkin SV

更新日期：2009-08-01 00:00:00

abstract：:Penetration of pegylated (enveloped in polyethylene glycol) gold nanoparticles 5 and 30 nm in diameter through the placental barrier was studied in pregnant rats injected intravenously with these particles in a dose of about 0.8 mg Au/kg on day 10 of gestation. The particles were visualized in tissues by silver nitrat...

journal_title：Bulletin of experimental biology and medicine

authors： Tsyganova NA,Khairullin RM,Terentyuk GS,Khlebtsov BN,Bogatyrev VA,Dykman LA,Erykov SN,Khlebtsov NG

更新日期：2014-07-01 00:00:00

abstract：:Over many years, tick-borne infections remain one of the most serious threats to human health worldwide. The immune response to these infections in a human after confirmed bite by an infected carrier at the early stages of infection in the absence of clinical symptoms can be the first indicator of the presence of the ...

journal_title：Bulletin of experimental biology and medicine

authors： Danchinova GA,Khasnatinov MA,Lyapunova NA,Solovarov IS,Manzarova EL,Lyapunov AV,Petrova IV

更新日期：2019-03-01 00:00:00

abstract：:We estimated the percentage of CD4+ lymphocytes synthesizing IFN-gamma and IL-4 in the peripheral blood and measured the concentrations of IL-1, IL-6, and TNF-alpha in lochia of patients with postpartum endometritis. T lymphocytes with intracellular IFN-gamma prevailed in women with physiological course of the postpar...

journal_title：Bulletin of experimental biology and medicine

authors： Sukhikh GT,Kasabulatov NM,Van'ko LV,Ordzhonikidze NV,Veryasov VN,Danelyan SZh

更新日期：2005-12-01 00:00:00

abstract：:In rat sinoatrial node, NAD(+) (10 μM) reduced the rate of spontaneous action potentials, duration of action potentials, and the velocity of slow diastolic depolarization, but the rate of action potential front propagation increases. In passed rabbit Purkinje fibers, NAD(+) (10 μM) reduced the duration of action poten...

journal_title：Bulletin of experimental biology and medicine

authors： Pustovit KB,Kuz'min VS,Sukhova GS

更新日期：2015-06-01 00:00:00

abstract：:Immunohistochemical and morphometric analysis of the microcirculatory bed in the tumor and non-tumor parenchyma of the prostate was carried out with the use of endothelial cell marker CD34 in patients treated by high-intensity focused ultrasound (HIFU). The numerical density of microvessels in the adenocarcinoma focus...

journal_title：Bulletin of experimental biology and medicine

authors： Bakarev MA,Levin VP,Kachesov IV,Abdullaev NA,Neimark AI

更新日期：2018-09-01 00:00:00