Introduction: innate recognition of bacteria and protozoan parasites.

Abstract:

:Major advances have recently been achieved in the area of microbial recognition by the innate immune system. In this Forum, we discuss important issues related to innate recognition of bacteria and protozoan parasites. In particular, we highlight the structural characterization of pathogen-associated molecular patterns (PAMPs); the definition of the receptors required for recognition of PAMPs, especially the Toll-like receptors (TLRs); the signaling pathways triggered by PAMPs/PAMPs receptor interaction; and the functional consequences of these interactions for pathogenesis during microbial infection.

journal_name

Microbes Infect

journal_title

Microbes and infection

authors

Teixeira MM,Almeida IC,Gazzinelli RT

doi

10.1016/s1286-4579(02)01625-8

subject

Has Abstract

pub_date

2002-07-01 00:00:00

pages

883-6

issue

9

eissn

1286-4579

issn

1769-714X

pii

S1286457902016258

journal_volume

4

pub_type

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