Abstract:
:Major advances have recently been achieved in the area of microbial recognition by the innate immune system. In this Forum, we discuss important issues related to innate recognition of bacteria and protozoan parasites. In particular, we highlight the structural characterization of pathogen-associated molecular patterns (PAMPs); the definition of the receptors required for recognition of PAMPs, especially the Toll-like receptors (TLRs); the signaling pathways triggered by PAMPs/PAMPs receptor interaction; and the functional consequences of these interactions for pathogenesis during microbial infection.
journal_name
Microbes Infectjournal_title
Microbes and infectionauthors
Teixeira MM,Almeida IC,Gazzinelli RTdoi
10.1016/s1286-4579(02)01625-8subject
Has Abstractpub_date
2002-07-01 00:00:00pages
883-6issue
9eissn
1286-4579issn
1769-714Xpii
S1286457902016258journal_volume
4pub_type
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