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Regulation of the generation and maintenance of T-cell memory: a direct, default pathway from effectors to memory cells.

Abstract：

:Memory T cells are derived directly from effector cells without need for additional antigen, TcR triggering or induced cytokines. A large fraction of effectors can become memory cells without division, supporting a default pathway with little further differentiation. This suggests that the same signals during infection/vaccination determine the extent and nature of both effector and memory cell development.

journal_name

Microbes Infect

journal_title

Microbes and infection

authors

Swain SL

doi

10.1016/s1286-4579(03)00013-3

subject

Has Abstract

pub_date

2003-03-01 00:00:00

pages

213-9

issue

3

eissn

1286-4579

issn

1769-714X

pii

S1286457903000133

journal_volume

5

pub_type

杂志文章,评审

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